TPM3 (tropomyosin 3)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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7170 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Tropomyosin 3 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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TPM3 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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CAPM1, CFTD, CMYO4A, CMYO4B, CMYP4A, CMYP4B, HEL-189, HEL-S-82p, NEM1, OK/SW-cl.5, TM-5, TM3, TM30, TM30nm, TM5, TPM3nu, TPMsk3, TRK, hscp30 |
Disease Acronyms (UniProt)
Disease acronyms from UniProt database
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CMYO4A, CMYO4B |
Chromosome
Chromosome number
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1 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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1q21.3 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the tropomyosin family of actin-binding proteins. Tropomyosins are dimers of coiled-coil proteins that provide stability to actin filaments and regulate access of other actin-binding proteins. Mutations in this gene result in |
SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | P06753 | ||||||||||
Protein name | Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3) (Tropomyosin-5) (hTM5) | ||||||||||
Protein function | Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by int | ||||||||||
PDB | 6OTN | ||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 285 | ||||||||||
Interactions | View interactions |
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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