Gene Gene information from NCBI Gene database.
Entrez ID 117178
Gene name SSX family member 2 interacting protein
Gene symbol SSX2IP
Synonyms (NCBI Gene)
ADIPhMsd1
Chromosome 1
Chromosome location 1p22.3
Summary This gene encodes a protein that binds the cancer-testis antigen Synovial Sarcoma X breakpoint 2 protein. The encoded protein may regulate the activity of Synovial Sarcoma X breakpoint 2 protein in malignant cells. Alternate splicing results in multiple t
miRNA miRNA information provided by mirtarbase database.
423
miRTarBase ID miRNA Experiments Reference
MIRT016383 hsa-miR-193b-3p Microarray 20304954
MIRT020713 hsa-miR-155-5p Reporter assay;Other 20584899
MIRT049125 hsa-miR-92a-3p CLASH 23622248
MIRT042758 hsa-miR-339-5p CLASH 23622248
MIRT053144 hsa-miR-222-3p Luciferase reporter assayqRT-PCR 23776679
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
25
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 12007189, 21516116, 21988832, 22458338, 24397932, 25416956, 25910212, 26545777, 26638075, 26675238, 26871637, 28514442, 31515488, 32296183, 33060197, 33961781, 36217029, 36931259
GO:0005634 Component Nucleus IEA
GO:0005737 Component Cytoplasm IEA
GO:0005813 Component Centrosome IDA
GO:0005856 Component Cytoskeleton IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
608690 16509 ENSG00000117155
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9Y2D8
Protein name Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain-interacting protein) (SSX2-interacting protein)
Protein function Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E-cadherin-catenin system through alpha-actinin and may be in
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF11559 ADIP 63 214 Afadin- and alpha -actinin-Binding Coiled-coil
Tissue specificity TISSUE SPECIFICITY: Widely expressed, with the highest expression in brain, intermediate expression in kidney, testis, spinal cord, liver, heart, lung, skeletal muscle, ovary, fetal liver and fetal brain, and little to no expression in pancreas and spleen
Sequence
MGDWMTVTDPGLSSESKTISQYTSETKMSPSSLYSQQVLCSSIPLSKNVHSFFSAFCTED
NIEQSISYLDQELTTFGFPSLYEESKGKETKRELNIVAVLNCMNELLVLQRKNLLAQENV
ETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEV
QKLQNIIASRATQYNHDMKRKEREYNKLKERLHQ
LVMNKKDKKIAMDILNYVGRADGKRG
SWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKKKPR
ERVDDSTGTVISDVEEDAGELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQV
SKVHLEGFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSLL
RDCYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAAIRLGLERKAFEEERASWLKQQFL
NMTTFDHQNSENVKLFSAFSGSSDWDNLIVHSRQPQKKPHSVSNGSPVCMSKLTKSLPAS
PSTSDFCQTRSCISEHSSINVLNITAEEIKPNQVGGECTNQKWSVASRPGSQEGCYSGCS
LSYTNSHVEKDDLP
Sequence length 614
Interactions View interactions