|
Unknown
Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
|
| Disease merge term |
Disease name |
Evidence |
References |
Source |
| Alzheimer disease |
Alzheimer's disease or family history of Alzheimer's disease |
N/A |
N/A |
GWAS |
| Diabetes Mellitus |
Type 2 diabetes mellitus |
N/A |
N/A |
ClinVar |
| Hypertension |
Hypertension |
N/A |
N/A |
GWAS |
| Multiple Sclerosis |
Multiple sclerosis |
N/A |
N/A |
GWAS |
|
|
Associations from Text Mining
Disease associations identified through Pubtator
|
| Disease Name |
Relationship Type |
References |
| Breast Neoplasms |
Associate
|
10950817, 34488531, 34525987 |
| Carcinogenesis |
Associate
|
33570246 |
| Carcinoma Non Small Cell Lung |
Associate
|
31180527, 37549925 |
| Cardiomegaly |
Stimulate
|
22028857 |
| Cardiomyopathy Hypertrophic |
Associate
|
32455814 |
| Colorectal Neoplasms |
Associate
|
29504525 |
| Coronary Disease |
Associate
|
35468725 |
| Dental Caries |
Associate
|
31261961 |
| Diabetes Gestational |
Stimulate
|
27981520 |
| Diabetes Gestational |
Associate
|
30805369, 35532201, 35712865 |
| Diabetes Mellitus |
Associate
|
16538490, 17107852, 28973736, 34360895, 37158952 |
| Diabetes Mellitus |
Stimulate
|
20602301, 27981520 |
| Diabetes Mellitus |
Inhibit
|
37174649 |
| Diabetes Mellitus Type 1 |
Associate
|
28973736 |
| Diabetes Mellitus Type 2 |
Associate
|
1918382, 20625434, 21796809, 22673408, 29382080, 30805369, 32851733, 33989714, 37520260 |
| Diabetes Mellitus Type 2 |
Inhibit
|
19816414, 1999488, 22114711, 28944847, 32455814, 35363363 |
| Diabetes Mellitus Type 2 |
Stimulate
|
20602301 |
| Diabetic Nephropathies |
Associate
|
36792603 |
| Diarrhea 5 With Tufting Enteropathy Congenital |
Associate
|
30049187 |
| Disease Progression |
Associate
|
22381410 |
| Drug Related Side Effects and Adverse Reactions |
Inhibit
|
26640142 |
| Gastrointestinal Stromal Tumors |
Associate
|
22381410, 34218261 |
| Harlequin type ichthyosis |
Inhibit
|
20011249 |
| Huntington Disease |
Associate
|
19118529 |
| Hyperglycemia |
Inhibit
|
22937169 |
| Hyperinsulinism |
Inhibit
|
35363363 |
| Hypertension |
Associate
|
24410986 |
| Hypogonadism |
Inhibit
|
26622051 |
| Hypoxia |
Associate
|
35711425 |
| Hypoxia |
Inhibit
|
37759548 |
| Hypoxia Brain |
Associate
|
23640464 |
| Inflammation |
Stimulate
|
19556978 |
| Inflammation |
Associate
|
26718495, 35485360 |
| Insulin Resistance |
Associate
|
16775236, 17227768, 21757715, 23805253, 26355033, 28944847, 29097553, 29333450, 30623452, 31389668, 32382742, 32662257, 32851733, 33509040, 35406631, 37453421 View all (1 more) |
| Insulin Resistance |
Stimulate
|
17986714 |
| Insulin Resistance |
Inhibit
|
22114711, 22403297, 23493574 |
| Leukemia Lymphocytic Chronic B Cell |
Associate
|
24828872 |
| Melanoma |
Associate
|
27786596 |
| Metabolic Diseases |
Associate
|
22381410 |
| Metabolic Syndrome |
Stimulate
|
23669880 |
| Metabolic Syndrome |
Associate
|
29504525, 37033267 |
| Multiple Myeloma |
Associate
|
22452979, 26640142, 35082341 |
| Multiple Sclerosis |
Inhibit
|
29504525 |
| Muscle Neoplasms |
Associate
|
29687616 |
| Muscular Diseases |
Associate
|
40141055 |
| Myopathies Structural Congenital |
Associate
|
36142275 |
| Neoplasm Metastasis |
Associate
|
27786596, 28061796, 29504525 |
| Neoplasms |
Associate
|
29382080, 29504525, 30419905, 36012230, 37549925 |
| Neoplasms |
Inhibit
|
34488531 |
| Neoplasms Adipose Tissue |
Associate
|
22309242 |
| Neurologic Manifestations |
Associate
|
19118529 |
| Obesity |
Inhibit
|
1999488, 22457223, 37174649 |
| Obesity |
Associate
|
27467133, 30813326, 32455814 |
| Obesity Morbid |
Inhibit
|
35363363 |
| Ovarian Neoplasms |
Associate
|
36012230 |
| Pancreatic Neoplasms |
Associate
|
9293784 |
| Pancreatitis |
Associate
|
9293784 |
| Polycystic Ovary Syndrome |
Inhibit
|
20011249, 23493574, 25064406 |
| Polycystic Ovary Syndrome |
Associate
|
30623452, 31874063, 32382742, 33228780, 35485360, 37047828 |
| Prostatic Neoplasms |
Associate
|
27121963, 31422041, 33619826 |
| Pulmonary Disease Chronic Obstructive |
Inhibit
|
18635880 |
| Sleep Apnea Obstructive |
Associate
|
24410986 |
| Squamous Cell Carcinoma of Head and Neck |
Associate
|
28061796, 30049187, 35920070, 37542344 |
| Stomach Neoplasms |
Associate
|
25925563, 31124603, 33570246 |
| Thyroid Cancer Papillary |
Inhibit
|
29978611 |
| Thyroid Cancer Papillary |
Associate
|
32425887 |
| Tremor |
Stimulate
|
31074654 |
|