Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
6517
Gene name Gene Name - the full gene name approved by the HGNC.
Solute carrier family 2 member 4
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
SLC2A4
Synonyms (NCBI Gene) Gene synonyms aliases
GLUT4
Chromosome Chromosome number
17
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
17p13.1
Summary Summary of gene provided in NCBI Entrez Gene.
This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is seque
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT006559 hsa-miR-223-3p Flow, Immunoblot, Immunofluorescence, Immunohistochemistry, Immunoprecipitaion, In situ hybridization, Luciferase reporter assay, Northern blot, qRT-PCR 20080987
MIRT019111 hsa-miR-335-5p Microarray 18185580
MIRT038921 hsa-miR-92a-1-5p CLASH 23622248
MIRT053085 hsa-miR-93-5p Luciferase reporter assay, qRT-PCR, Western blot 23493574
MIRT611339 hsa-miR-548ac HITS-CLIP 23824327
Transcription factors
Transcription factor Regulation Reference
HDAC4 Unknown 23899560
HDAC5 Repression 22991226
HDAC5 Unknown 23899560
MEF2A Activation 14630949;18198354
MEF2A Unknown 15294043
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005355 Function Glucose transmembrane transporter activity ISS
GO:0005515 Function Protein binding IPI 19478182, 25910212
GO:0005771 Component Multivesicular body IEA
GO:0005802 Component Trans-Golgi network IDA 12467732
GO:0005829 Component Cytosol IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
138190 11009 ENSG00000181856
Protein
UniProt ID P14672
Protein name Solute carrier family 2, facilitated glucose transporter member 4 (Glucose transporter type 4, insulin-responsive) (GLUT-4)
Protein function Insulin-regulated facilitative glucose transporter, which plays a key role in removal of glucose from circulation. Response to insulin is regulated by its intracellular localization: in the absence of insulin, it is efficiently retained intracel
PDB 7WSM , 7WSN
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00083 Sugar_tr 27 483 Sugar (and other) transporter Family
Tissue specificity TISSUE SPECIFICITY: Skeletal and cardiac muscles; brown and white fat.
Sequence
Sequence length 509
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Unknown
Disease term Disease name Evidence References Source
Multiple Sclerosis Multiple Sclerosis GWAS
Alzheimer disease Alzheimer disease GWAS
Hypertension Hypertension GWAS
Associations from Text Mining
Disease Name Relationship Type References
Breast Neoplasms Associate 10950817, 34488531, 34525987
Carcinogenesis Associate 33570246
Carcinoma Non Small Cell Lung Associate 31180527, 37549925
Cardiomegaly Stimulate 22028857
Cardiomyopathy Hypertrophic Associate 32455814
Colorectal Neoplasms Associate 29504525
Coronary Disease Associate 35468725
Dental Caries Associate 31261961
Diabetes Gestational Stimulate 27981520
Diabetes Gestational Associate 30805369, 35532201, 35712865