SEL1L (SEL1L adaptor subunit of SYVN1 ubiquitin ligase)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
6400 |
Gene name
Gene Name - the full gene name approved by the HGNC.
|
SEL1L adaptor subunit of SYVN1 ubiquitin ligase |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
|
SEL1L |
Synonyms (NCBI Gene)
Gene synonyms aliases
|
Hrd3, NEDGSAF, NEDHGFA, PRO1063, SEL1-LIKE, SEL1L1 |
Disease Acronyms (UniProt)
Disease acronyms from UniProt database
|
NEDGSAF, NEDHGFA |
Chromosome
Chromosome number
|
14 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
14q31.1 |
Summary
Summary of gene provided in NCBI Entrez Gene.
|
The protein encoded by this gene is part of a protein complex required for the retrotranslocation or dislocation of misfolded proteins from the endoplasmic reticulum lumen to the cytosol, where they are degraded by the proteasome in a ubiquitin-dependent |
miRNA
miRNA information provided by mirtarbase database.
|
|||||||||||||||||||||||||
|
Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
|
|||||||||||||||||||||||||||||||
|
Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
|
|||||||
|
Protein | |||||||||||||||||||||||||||||||||||||||||||||||||||
UniProt ID | Q9UBV2 | ||||||||||||||||||||||||||||||||||||||||||||||||||
Protein name | Protein sel-1 homolog 1 (Suppressor of lin-12-like protein 1) (Sel-1L) | ||||||||||||||||||||||||||||||||||||||||||||||||||
Protein function | Plays a role in the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins (PubMed:16186509, PubMed:29997207, PubMe | ||||||||||||||||||||||||||||||||||||||||||||||||||
PDB | 8KES , 8KET , 8KEV | ||||||||||||||||||||||||||||||||||||||||||||||||||
Family and domains |
Pfam
|
||||||||||||||||||||||||||||||||||||||||||||||||||
Tissue specificity | TISSUE SPECIFICITY: Highly expressed in pancreas. | ||||||||||||||||||||||||||||||||||||||||||||||||||
Sequence |
|
||||||||||||||||||||||||||||||||||||||||||||||||||
Sequence length | 794 | ||||||||||||||||||||||||||||||||||||||||||||||||||
Interactions | View interactions |