SDC2 (syndecan 2)

Gene

• Entrez ID: 6383
• Gene name: Syndecan 2
• Gene symbol: SDC2
• Synonyms (NCBI Gene): CD362, HSPG, HSPG1, SYND2
• Chromosome: 8
• Chromosome location: 8q22.1
• Summary: The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are req

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT468760	hsa-miR-495-3p	PAR-CLIP	23592263
MIRT468759	hsa-miR-5688	PAR-CLIP	23592263
MIRT468758	hsa-miR-7-1-3p	PAR-CLIP	23592263
MIRT468757	hsa-miR-7-2-3p	PAR-CLIP	23592263
MIRT468756	hsa-miR-3125	PAR-CLIP	23592263
MIRT468755	hsa-miR-3916	PAR-CLIP	23592263
MIRT468754	hsa-miR-6859-5p	PAR-CLIP	23592263
MIRT468753	hsa-miR-577	PAR-CLIP	23592263
MIRT468752	hsa-miR-4476	PAR-CLIP	23592263
MIRT468751	hsa-miR-6876-5p	PAR-CLIP	23592263
MIRT468750	hsa-miR-4436b-3p	PAR-CLIP	23592263
MIRT468749	hsa-miR-4632-5p	PAR-CLIP	23592263
MIRT468748	hsa-miR-6735-5p	PAR-CLIP	23592263
MIRT468747	hsa-miR-6879-5p	PAR-CLIP	23592263
MIRT468746	hsa-miR-7843-5p	PAR-CLIP	23592263
MIRT468745	hsa-miR-6847-5p	PAR-CLIP	23592263
MIRT468744	hsa-miR-3179	PAR-CLIP	23592263
MIRT468743	hsa-miR-3150b-3p	PAR-CLIP	23592263
MIRT468742	hsa-miR-4784	PAR-CLIP	23592263
MIRT468741	hsa-miR-3616-3p	PAR-CLIP	23592263
MIRT468740	hsa-miR-2467-3p	PAR-CLIP	23592263
MIRT468739	hsa-miR-3202	PAR-CLIP	23592263
MIRT468760	hsa-miR-495-3p	PAR-CLIP	23592263
MIRT468759	hsa-miR-5688	PAR-CLIP	23592263
MIRT468758	hsa-miR-7-1-3p	PAR-CLIP	23592263
MIRT468757	hsa-miR-7-2-3p	PAR-CLIP	23592263
MIRT468756	hsa-miR-3125	PAR-CLIP	23592263
MIRT468755	hsa-miR-3916	PAR-CLIP	23592263
MIRT468754	hsa-miR-6859-5p	PAR-CLIP	23592263
MIRT468753	hsa-miR-577	PAR-CLIP	23592263
MIRT468752	hsa-miR-4476	PAR-CLIP	23592263
MIRT468751	hsa-miR-6876-5p	PAR-CLIP	23592263
MIRT468750	hsa-miR-4436b-3p	PAR-CLIP	23592263
MIRT468749	hsa-miR-4632-5p	PAR-CLIP	23592263
MIRT468748	hsa-miR-6735-5p	PAR-CLIP	23592263
MIRT468747	hsa-miR-6879-5p	PAR-CLIP	23592263
MIRT468746	hsa-miR-7843-5p	PAR-CLIP	23592263
MIRT468745	hsa-miR-6847-5p	PAR-CLIP	23592263
MIRT468744	hsa-miR-3179	PAR-CLIP	23592263
MIRT468743	hsa-miR-3150b-3p	PAR-CLIP	23592263
MIRT468742	hsa-miR-4784	PAR-CLIP	23592263
MIRT468741	hsa-miR-3616-3p	PAR-CLIP	23592263
MIRT468740	hsa-miR-2467-3p	PAR-CLIP	23592263
MIRT468739	hsa-miR-3202	PAR-CLIP	23592263
MIRT1331299	hsa-miR-1271	CLIP-seq
MIRT1331300	hsa-miR-182	CLIP-seq
MIRT1331301	hsa-miR-3190	CLIP-seq
MIRT1331302	hsa-miR-3200-5p	CLIP-seq
MIRT1331303	hsa-miR-331-3p	CLIP-seq
MIRT1331304	hsa-miR-3622b-5p	CLIP-seq
MIRT1331305	hsa-miR-3646	CLIP-seq
MIRT1331306	hsa-miR-3647-3p	CLIP-seq
MIRT1331307	hsa-miR-3941	CLIP-seq
MIRT1331308	hsa-miR-4251	CLIP-seq
MIRT1331309	hsa-miR-4257	CLIP-seq
MIRT1331310	hsa-miR-4329	CLIP-seq
MIRT1331311	hsa-miR-4642	CLIP-seq
MIRT1331312	hsa-miR-4643	CLIP-seq
MIRT1331313	hsa-miR-466	CLIP-seq
MIRT1331314	hsa-miR-4670-3p	CLIP-seq
MIRT1331315	hsa-miR-4672	CLIP-seq
MIRT1331316	hsa-miR-4704-5p	CLIP-seq
MIRT1331317	hsa-miR-4719	CLIP-seq
MIRT1331318	hsa-miR-4728-3p	CLIP-seq
MIRT1331319	hsa-miR-4775	CLIP-seq
MIRT1331320	hsa-miR-4789-3p	CLIP-seq
MIRT1331321	hsa-miR-4789-5p	CLIP-seq
MIRT1331322	hsa-miR-494	CLIP-seq
MIRT1331323	hsa-miR-499a-5p	CLIP-seq
MIRT1331324	hsa-miR-561	CLIP-seq
MIRT1331325	hsa-miR-590-3p	CLIP-seq
MIRT1331326	hsa-miR-605	CLIP-seq
MIRT1331327	hsa-miR-628-5p	CLIP-seq
MIRT1331328	hsa-miR-642b	CLIP-seq
MIRT1331329	hsa-miR-885-3p	CLIP-seq
MIRT1331330	hsa-miR-96	CLIP-seq
MIRT1553262	hsa-miR-3148	CLIP-seq
MIRT1553263	hsa-miR-3149	CLIP-seq
MIRT1553264	hsa-miR-4496	CLIP-seq
MIRT1331316	hsa-miR-4704-5p	CLIP-seq
MIRT1553265	hsa-miR-4762-5p	CLIP-seq
MIRT1331319	hsa-miR-4775	CLIP-seq
MIRT1331321	hsa-miR-4789-5p	CLIP-seq
MIRT1553266	hsa-miR-4796-3p	CLIP-seq
MIRT1331325	hsa-miR-590-3p	CLIP-seq
MIRT1553267	hsa-miR-627	CLIP-seq
MIRT1331319	hsa-miR-4775	CLIP-seq
MIRT2322548	hsa-miR-103a	CLIP-seq
MIRT2322549	hsa-miR-107	CLIP-seq
MIRT2322550	hsa-miR-1184	CLIP-seq
MIRT2322551	hsa-miR-1205	CLIP-seq
MIRT2322552	hsa-miR-1283	CLIP-seq
MIRT2322553	hsa-miR-25	CLIP-seq
MIRT1553262	hsa-miR-3148	CLIP-seq
MIRT1553263	hsa-miR-3149	CLIP-seq
MIRT2322554	hsa-miR-3158-5p	CLIP-seq
MIRT2322555	hsa-miR-32	CLIP-seq
MIRT1331302	hsa-miR-3200-5p	CLIP-seq
MIRT2322556	hsa-miR-363	CLIP-seq
MIRT1331305	hsa-miR-3646	CLIP-seq
MIRT2322557	hsa-miR-367	CLIP-seq
MIRT2322558	hsa-miR-4307	CLIP-seq
MIRT1553264	hsa-miR-4496	CLIP-seq
MIRT2322559	hsa-miR-4666-3p	CLIP-seq
MIRT2322560	hsa-miR-4680-3p	CLIP-seq
MIRT1331317	hsa-miR-4719	CLIP-seq
MIRT2322561	hsa-miR-4781-3p	CLIP-seq
MIRT1331321	hsa-miR-4789-5p	CLIP-seq
MIRT1331322	hsa-miR-494	CLIP-seq
MIRT1553267	hsa-miR-627	CLIP-seq
MIRT1331328	hsa-miR-642b	CLIP-seq
MIRT2322562	hsa-miR-659	CLIP-seq
MIRT2322563	hsa-miR-767-5p	CLIP-seq
MIRT2322564	hsa-miR-891b	CLIP-seq
MIRT2322565	hsa-miR-9	CLIP-seq
MIRT2322566	hsa-miR-92a	CLIP-seq
MIRT2322567	hsa-miR-92b	CLIP-seq
MIRT2322552	hsa-miR-1283	CLIP-seq
MIRT2394131	hsa-miR-199a-3p	CLIP-seq
MIRT2394132	hsa-miR-199b-3p	CLIP-seq
MIRT2394133	hsa-miR-3129-5p	CLIP-seq
MIRT2394134	hsa-miR-936	CLIP-seq
MIRT2322552	hsa-miR-1283	CLIP-seq
MIRT2432940	hsa-miR-296-3p	CLIP-seq
MIRT1331305	hsa-miR-3646	CLIP-seq
MIRT1331306	hsa-miR-3647-3p	CLIP-seq
MIRT2432941	hsa-miR-3910	CLIP-seq
MIRT1331316	hsa-miR-4704-5p	CLIP-seq
MIRT1331317	hsa-miR-4719	CLIP-seq
MIRT1331321	hsa-miR-4789-5p	CLIP-seq
MIRT1331322	hsa-miR-494	CLIP-seq
MIRT2432942	hsa-miR-548an	CLIP-seq
MIRT1553267	hsa-miR-627	CLIP-seq
MIRT1331328	hsa-miR-642b	CLIP-seq
MIRT2440060	hsa-miR-3156-5p	CLIP-seq
MIRT1331305	hsa-miR-3646	CLIP-seq
MIRT1553264	hsa-miR-4496	CLIP-seq
MIRT1331317	hsa-miR-4719	CLIP-seq
MIRT1331322	hsa-miR-494	CLIP-seq
MIRT1553267	hsa-miR-627	CLIP-seq
MIRT1331328	hsa-miR-642b	CLIP-seq
MIRT2618679	hsa-miR-1245	CLIP-seq
MIRT2322552	hsa-miR-1283	CLIP-seq
MIRT2618680	hsa-miR-1321	CLIP-seq
MIRT2618681	hsa-miR-2277-3p	CLIP-seq
MIRT2432940	hsa-miR-296-3p	CLIP-seq
MIRT2618682	hsa-miR-300	CLIP-seq
MIRT2618683	hsa-miR-3117-5p	CLIP-seq
MIRT2618684	hsa-miR-3121-3p	CLIP-seq
MIRT1553262	hsa-miR-3148	CLIP-seq
MIRT1553263	hsa-miR-3149	CLIP-seq
MIRT2618685	hsa-miR-3154	CLIP-seq
MIRT1331301	hsa-miR-3190	CLIP-seq
MIRT1331305	hsa-miR-3646	CLIP-seq
MIRT2618686	hsa-miR-381	CLIP-seq
MIRT2432941	hsa-miR-3910	CLIP-seq
MIRT2618687	hsa-miR-3976	CLIP-seq
MIRT2618688	hsa-miR-4282	CLIP-seq
MIRT2618689	hsa-miR-4477b	CLIP-seq
MIRT1553264	hsa-miR-4496	CLIP-seq
MIRT2322559	hsa-miR-4666-3p	CLIP-seq
MIRT1331314	hsa-miR-4670-3p	CLIP-seq
MIRT2618690	hsa-miR-4695-3p	CLIP-seq
MIRT1331317	hsa-miR-4719	CLIP-seq
MIRT2618691	hsa-miR-4728-5p	CLIP-seq
MIRT2618692	hsa-miR-4739	CLIP-seq
MIRT2618693	hsa-miR-4756-5p	CLIP-seq
MIRT1331321	hsa-miR-4789-5p	CLIP-seq
MIRT1553266	hsa-miR-4796-3p	CLIP-seq
MIRT2618694	hsa-miR-4803	CLIP-seq
MIRT1331322	hsa-miR-494	CLIP-seq
MIRT2618695	hsa-miR-520d-5p	CLIP-seq
MIRT2618696	hsa-miR-520g	CLIP-seq
MIRT2618697	hsa-miR-520h	CLIP-seq
MIRT2618698	hsa-miR-524-5p	CLIP-seq
MIRT2432942	hsa-miR-548an	CLIP-seq
MIRT2618699	hsa-miR-548c-3p	CLIP-seq
MIRT2618700	hsa-miR-548n	CLIP-seq
MIRT2618701	hsa-miR-548t	CLIP-seq
MIRT1331324	hsa-miR-561	CLIP-seq
MIRT1553267	hsa-miR-627	CLIP-seq
MIRT1331328	hsa-miR-642b	CLIP-seq
MIRT2322562	hsa-miR-659	CLIP-seq
MIRT2322552	hsa-miR-1283	CLIP-seq
MIRT2618680	hsa-miR-1321	CLIP-seq
MIRT2618681	hsa-miR-2277-3p	CLIP-seq
MIRT2432940	hsa-miR-296-3p	CLIP-seq
MIRT1553262	hsa-miR-3148	CLIP-seq
MIRT1553263	hsa-miR-3149	CLIP-seq
MIRT2618685	hsa-miR-3154	CLIP-seq
MIRT1331305	hsa-miR-3646	CLIP-seq
MIRT2432941	hsa-miR-3910	CLIP-seq
MIRT2618689	hsa-miR-4477b	CLIP-seq
MIRT1553264	hsa-miR-4496	CLIP-seq
MIRT1331317	hsa-miR-4719	CLIP-seq
MIRT2618692	hsa-miR-4739	CLIP-seq
MIRT2618693	hsa-miR-4756-5p	CLIP-seq
MIRT1331322	hsa-miR-494	CLIP-seq
MIRT2432942	hsa-miR-548an	CLIP-seq
MIRT2618700	hsa-miR-548n	CLIP-seq
MIRT2618701	hsa-miR-548t	CLIP-seq
MIRT1331324	hsa-miR-561	CLIP-seq
MIRT1553267	hsa-miR-627	CLIP-seq
MIRT1331328	hsa-miR-642b	CLIP-seq
MIRT2322562	hsa-miR-659	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	9660868, 11356864, 18093920, 22660413, 32296183, 32814053, 33961781
GO:0005788	Component	Endoplasmic reticulum lumen	TAS
GO:0005796	Component	Golgi lumen	TAS
GO:0005886	Component	Plasma membrane	IDA
GO:0005886	Component	Plasma membrane	TAS
GO:0007399	Process	Nervous system development	IEA
GO:0009986	Component	Cell surface	IBA
GO:0016020	Component	Membrane	IEA
GO:0016477	Process	Cell migration	IBA
GO:0030154	Process	Cell differentiation	IEA
GO:0030165	Function	PDZ domain binding	IPI	18256285
GO:0031012	Component	Extracellular matrix	HDA	27068509
GO:0042802	Function	Identical protein binding	IPI	18093920, 21988832
GO:0043202	Component	Lysosomal lumen	TAS
GO:0048813	Process	Dendrite morphogenesis	IBA
GO:0048814	Process	Regulation of dendrite morphogenesis	IEA
GO:0048814	Process	Regulation of dendrite morphogenesis	ISS

Other IDs

• MIM: 142460
• HGNC: 10659
• e!Ensembl: ENSG00000169439

Protein

• UniProt ID: P34741
• Protein name: Syndecan-2 (SYND2) (Fibroglycan) (Heparan sulfate proteoglycan core protein) (HSPG) (CD antigen CD362)
• Protein function: Cell surface proteoglycan which regulates dendritic arbor morphogenesis.
• PDB: 6ITH
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01034	Syndecan	138 → 199	Syndecan domain	Family

• Sequence:

  MRRAWILLTLGLVACVSAESRAELTSDKDMYLDNSSIEEASGVYPIDDDDYASASGSGAD
  EDVESPELTTSRPLPKILLTSAAPKVETTTLNIQNKIPAQTKSPEETDKEKVHLSDSERK
  MDPAEEDTNVYTEKHSDSLFKRTEVLAAVIAGGVIGFLFAIFLILLLVYRMRKKDEGSYD
  LGERKPSSAAYQKAPTKEFYA

• Sequence length: 201