RPS6KA5 (ribosomal protein S6 kinase A5)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 9252 |
| Gene name | Ribosomal protein S6 kinase A5 |
| Gene symbol | RPS6KA5 |
| Synonyms (NCBI Gene) |
MSK1MSPK1RLPK
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| Chromosome | 14 |
| Chromosome location | 14q32.11 |
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miRNA
miRNA information provided by mirtarbase database.
436
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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O75582 | ||||||||||||||||||||
| Protein name | Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 5) (Nuclear mitogen- and stress-activated protein kinase 1) (RSK-like protein kinase) (RSKL) | ||||||||||||||||||||
| Protein function | Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to | ||||||||||||||||||||
| PDB | 1VZO , 3KN5 , 3KN6 , 7UP4 , 7UP5 , 7UP6 , 7UP7 , 7UP8 | ||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Widely expressed with high levels in heart, brain and placenta. Less abundant in lung, kidney and liver. {ECO:0000269|PubMed:9687510, ECO:0000269|PubMed:9873047}. | ||||||||||||||||||||
| Sequence |
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| Sequence length | 802 | ||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
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