Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
91445
Gene name Gene Name - the full gene name approved by the HGNC.
Ring finger protein 185
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
RNF185
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
22
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
22q12.2
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT042563 hsa-miR-423-3p CLASH 23622248
MIRT040228 hsa-miR-615-3p CLASH 23622248
MIRT499677 hsa-miR-551b-5p PAR-CLIP 24398324
MIRT205530 hsa-miR-3125 PAR-CLIP 24398324
MIRT205532 hsa-miR-3916 PAR-CLIP 24398324
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 19549727, 21931693, 24019521, 25416956, 28514442, 31515488, 32296183
GO:0005741 Component Mitochondrial outer membrane IEA
GO:0005783 Component Endoplasmic reticulum IDA 24019521, 27485036
GO:0005789 Component Endoplasmic reticulum membrane NAS 24019521
GO:0005789 Component Endoplasmic reticulum membrane TAS
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
620096 26783 ENSG00000138942
Protein
UniProt ID Q96GF1
Protein name E3 ubiquitin-protein ligase RNF185 (EC 2.3.2.27) (RING finger protein 185)
Protein function E3 ubiquitin-protein ligase that regulates selective mitochondrial autophagy by mediating 'Lys-63'-linked polyubiquitination of BNIP1 (PubMed:21931693). Acts in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway, which targets
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF13920 zf-C3HC4_3 35 85 Domain
Tissue specificity TISSUE SPECIFICITY: Ubiquitously expressed. {ECO:0000269|PubMed:27485036}.
Sequence
MASKGPSASASPENSSAGGPSGSSNGAGESGGQDSTFECNICLDTAKDAVISLCGHLFCW
PCLHQWLETRPNRQVCPVCKAGISR
DKVIPLYGRGSTGQQDPREKTPPRPQGQRPEPENR
GGFQGFGFGDGGFQMSFGIGAFPFGIFATAFNINDGRPPPAVPGTPQYVDEQFLSRLFLF
VALVIMFWLLIA
Sequence length 192
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Unknown
Disease term Disease name Evidence References Source
Tremor Tremor GWAS
Associations from Text Mining
Disease Name Relationship Type References
Glioblastoma Associate 35183197
Glioma Inhibit 35183197
Lupus Erythematosus Systemic Stimulate 28273161
Neoplasms Inhibit 35183197