Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs Other IDs Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	57494
Gene name Gene Name - the full gene name approved by the HGNC.	Ribosomal modification protein rimK like family member B
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	RIMKLB
Synonyms (NCBI Gene) Gene synonyms aliases	FAM80B, NAAGS, NAAGS-I
Chromosome Chromosome number	12
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	12p13.31

Show/Hide all(267)

miRTarBase ID	miRNA	Experiments	Reference
MIRT700188	hsa-miR-4323	HITS-CLIP	23313552
MIRT700187	hsa-miR-520f-5p	HITS-CLIP	23313552
MIRT700186	hsa-miR-4667-5p	HITS-CLIP	23313552
MIRT700185	hsa-miR-4700-5p	HITS-CLIP	23313552
MIRT700184	hsa-miR-8089	HITS-CLIP	23313552
MIRT700183	hsa-miR-5699-5p	HITS-CLIP	23313552
MIRT700182	hsa-miR-4758-3p	HITS-CLIP	23313552
MIRT700181	hsa-miR-4450	HITS-CLIP	23313552
MIRT700180	hsa-miR-6895-3p	HITS-CLIP	23313552
MIRT700179	hsa-miR-593-3p	HITS-CLIP	23313552
MIRT700178	hsa-miR-513b-5p	HITS-CLIP	23313552
MIRT700177	hsa-miR-181b-2-3p	HITS-CLIP	23313552
MIRT700176	hsa-miR-181b-3p	HITS-CLIP	23313552
MIRT700175	hsa-miR-4420	HITS-CLIP	23313552
MIRT700174	hsa-miR-653-3p	HITS-CLIP	23313552
MIRT700173	hsa-miR-6857-5p	HITS-CLIP	23313552
MIRT700172	hsa-miR-6818-3p	HITS-CLIP	23313552
MIRT067440	hsa-miR-8066	PAR-CLIP	22100165
MIRT441937	hsa-miR-636	PAR-CLIP	22100165
MIRT441936	hsa-miR-1273e	PAR-CLIP	22100165
MIRT441935	hsa-miR-218-5p	PAR-CLIP	22100165
MIRT067440	hsa-miR-8066	PAR-CLIP	22100165
MIRT446290	hsa-miR-3973	PAR-CLIP	22100165
MIRT446289	hsa-miR-520g-3p	PAR-CLIP	22100165
MIRT446288	hsa-miR-520h	PAR-CLIP	22100165
MIRT441937	hsa-miR-636	PAR-CLIP	22100165
MIRT441936	hsa-miR-1273e	PAR-CLIP	22100165
MIRT441935	hsa-miR-218-5p	PAR-CLIP	22100165
MIRT441940	hsa-miR-3184-3p	PAR-CLIP	22100165
MIRT441939	hsa-miR-3691-3p	PAR-CLIP	22100165
MIRT441938	hsa-miR-4480	PAR-CLIP	22100165
MIRT441937	hsa-miR-636	PAR-CLIP	22100165
MIRT441936	hsa-miR-1273e	PAR-CLIP	22100165
MIRT441935	hsa-miR-218-5p	PAR-CLIP	22100165
MIRT700188	hsa-miR-4323	HITS-CLIP	23313552
MIRT700187	hsa-miR-520f-5p	HITS-CLIP	23313552
MIRT700186	hsa-miR-4667-5p	HITS-CLIP	23313552
MIRT700185	hsa-miR-4700-5p	HITS-CLIP	23313552
MIRT700184	hsa-miR-8089	HITS-CLIP	23313552
MIRT700183	hsa-miR-5699-5p	HITS-CLIP	23313552
MIRT700182	hsa-miR-4758-3p	HITS-CLIP	23313552
MIRT700181	hsa-miR-4450	HITS-CLIP	23313552
MIRT700180	hsa-miR-6895-3p	HITS-CLIP	23313552
MIRT700179	hsa-miR-593-3p	HITS-CLIP	23313552
MIRT700178	hsa-miR-513b-5p	HITS-CLIP	23313552
MIRT700177	hsa-miR-181b-2-3p	HITS-CLIP	23313552
MIRT700176	hsa-miR-181b-3p	HITS-CLIP	23313552
MIRT700175	hsa-miR-4420	HITS-CLIP	23313552
MIRT700174	hsa-miR-653-3p	HITS-CLIP	23313552
MIRT700173	hsa-miR-6857-5p	HITS-CLIP	23313552
MIRT700172	hsa-miR-6818-3p	HITS-CLIP	23313552
MIRT067440	hsa-miR-8066	PAR-CLIP	22100165
MIRT441937	hsa-miR-636	PAR-CLIP	22100165
MIRT441936	hsa-miR-1273e	PAR-CLIP	22100165
MIRT441935	hsa-miR-218-5p	PAR-CLIP	22100165
MIRT067440	hsa-miR-8066	PAR-CLIP	22100165
MIRT446290	hsa-miR-3973	PAR-CLIP	22100165
MIRT446289	hsa-miR-520g-3p	PAR-CLIP	22100165
MIRT446288	hsa-miR-520h	PAR-CLIP	22100165
MIRT441937	hsa-miR-636	PAR-CLIP	22100165
MIRT441936	hsa-miR-1273e	PAR-CLIP	22100165
MIRT441935	hsa-miR-218-5p	PAR-CLIP	22100165
MIRT441940	hsa-miR-3184-3p	PAR-CLIP	22100165
MIRT441939	hsa-miR-3691-3p	PAR-CLIP	22100165
MIRT441938	hsa-miR-4480	PAR-CLIP	22100165
MIRT441937	hsa-miR-636	PAR-CLIP	22100165
MIRT441936	hsa-miR-1273e	PAR-CLIP	22100165
MIRT441935	hsa-miR-218-5p	PAR-CLIP	22100165
MIRT1306865	hsa-miR-1200	CLIP-seq
MIRT1306866	hsa-miR-1206	CLIP-seq
MIRT1306867	hsa-miR-1244	CLIP-seq
MIRT1306868	hsa-miR-1245b-3p	CLIP-seq
MIRT1306869	hsa-miR-1251	CLIP-seq
MIRT1306870	hsa-miR-1252	CLIP-seq
MIRT1306871	hsa-miR-1270	CLIP-seq
MIRT1306872	hsa-miR-137	CLIP-seq
MIRT1306873	hsa-miR-142-3p	CLIP-seq
MIRT1306874	hsa-miR-185	CLIP-seq
MIRT1306875	hsa-miR-200b	CLIP-seq
MIRT1306876	hsa-miR-200c	CLIP-seq
MIRT1306877	hsa-miR-202	CLIP-seq
MIRT1306878	hsa-miR-203	CLIP-seq
MIRT1306879	hsa-miR-2053	CLIP-seq
MIRT1306880	hsa-miR-2117	CLIP-seq
MIRT1306881	hsa-miR-218	CLIP-seq
MIRT1306882	hsa-miR-2681	CLIP-seq
MIRT1306883	hsa-miR-297	CLIP-seq
MIRT1306884	hsa-miR-300	CLIP-seq
MIRT1306885	hsa-miR-3074-5p	CLIP-seq
MIRT1306886	hsa-miR-31	CLIP-seq
MIRT1306887	hsa-miR-3148	CLIP-seq
MIRT1306888	hsa-miR-3152-5p	CLIP-seq
MIRT1306889	hsa-miR-325	CLIP-seq
MIRT1306890	hsa-miR-3607-5p	CLIP-seq
MIRT1306891	hsa-miR-3613-3p	CLIP-seq
MIRT1306892	hsa-miR-3620	CLIP-seq
MIRT1306893	hsa-miR-3659	CLIP-seq
MIRT1306894	hsa-miR-3680	CLIP-seq
MIRT1306895	hsa-miR-371-5p	CLIP-seq
MIRT1306896	hsa-miR-371b-5p	CLIP-seq
MIRT1306897	hsa-miR-374c	CLIP-seq
MIRT1306898	hsa-miR-381	CLIP-seq
MIRT1306899	hsa-miR-3924	CLIP-seq
MIRT1306900	hsa-miR-3974	CLIP-seq
MIRT1306901	hsa-miR-4257	CLIP-seq
MIRT1306902	hsa-miR-4273	CLIP-seq
MIRT1306903	hsa-miR-429	CLIP-seq
MIRT1306904	hsa-miR-4297	CLIP-seq
MIRT1306905	hsa-miR-4306	CLIP-seq
MIRT1306906	hsa-miR-4307	CLIP-seq
MIRT1306907	hsa-miR-4422	CLIP-seq
MIRT1306908	hsa-miR-4434	CLIP-seq
MIRT1306909	hsa-miR-4438	CLIP-seq
MIRT1306910	hsa-miR-4477a	CLIP-seq
MIRT1306911	hsa-miR-4477b	CLIP-seq
MIRT1306912	hsa-miR-4501	CLIP-seq
MIRT1306913	hsa-miR-4516	CLIP-seq
MIRT1306914	hsa-miR-4531	CLIP-seq
MIRT1306915	hsa-miR-4637	CLIP-seq
MIRT1306916	hsa-miR-4644	CLIP-seq
MIRT1306917	hsa-miR-4652-3p	CLIP-seq
MIRT1306918	hsa-miR-4658	CLIP-seq
MIRT1306919	hsa-miR-4666-3p	CLIP-seq
MIRT1306920	hsa-miR-4678	CLIP-seq
MIRT1306921	hsa-miR-4699-5p	CLIP-seq
MIRT1306922	hsa-miR-4712-3p	CLIP-seq
MIRT1306923	hsa-miR-4724-5p	CLIP-seq
MIRT1306924	hsa-miR-4731-3p	CLIP-seq
MIRT1306925	hsa-miR-4789-5p	CLIP-seq
MIRT1306926	hsa-miR-4795-3p	CLIP-seq
MIRT1306927	hsa-miR-4798-3p	CLIP-seq
MIRT1306928	hsa-miR-4801	CLIP-seq
MIRT1306929	hsa-miR-495	CLIP-seq
MIRT1306930	hsa-miR-513b	CLIP-seq
MIRT1306931	hsa-miR-513c	CLIP-seq
MIRT1306932	hsa-miR-514b-5p	CLIP-seq
MIRT1306933	hsa-miR-520g	CLIP-seq
MIRT1306934	hsa-miR-532-5p	CLIP-seq
MIRT1306935	hsa-miR-548g	CLIP-seq
MIRT1306936	hsa-miR-548l	CLIP-seq
MIRT1306937	hsa-miR-548n	CLIP-seq
MIRT1306938	hsa-miR-548u	CLIP-seq
MIRT1306939	hsa-miR-567	CLIP-seq
MIRT1306940	hsa-miR-569	CLIP-seq
MIRT1306941	hsa-miR-574-5p	CLIP-seq
MIRT1306942	hsa-miR-593	CLIP-seq
MIRT1306943	hsa-miR-606	CLIP-seq
MIRT1306944	hsa-miR-607	CLIP-seq
MIRT1306945	hsa-miR-620	CLIP-seq
MIRT1306946	hsa-miR-628-3p	CLIP-seq
MIRT1306947	hsa-miR-655	CLIP-seq
MIRT1306948	hsa-miR-889	CLIP-seq
MIRT1306887	hsa-miR-3148	CLIP-seq
MIRT1306879	hsa-miR-2053	CLIP-seq
MIRT2090996	hsa-miR-2276	CLIP-seq
MIRT2090997	hsa-miR-3908	CLIP-seq
MIRT2090998	hsa-miR-3942-5p	CLIP-seq
MIRT1306901	hsa-miR-4257	CLIP-seq
MIRT2090999	hsa-miR-452	CLIP-seq
MIRT1306919	hsa-miR-4666-3p	CLIP-seq
MIRT2091000	hsa-miR-4676-3p	CLIP-seq
MIRT2091001	hsa-miR-4703-5p	CLIP-seq
MIRT2091002	hsa-miR-4762-5p	CLIP-seq
MIRT2091003	hsa-miR-4766-3p	CLIP-seq
MIRT2091004	hsa-miR-4772-3p	CLIP-seq
MIRT1306925	hsa-miR-4789-5p	CLIP-seq
MIRT2091005	hsa-miR-544	CLIP-seq
MIRT2315698	hsa-miR-1273f	CLIP-seq
MIRT2315699	hsa-miR-1276	CLIP-seq
MIRT2315700	hsa-miR-1289	CLIP-seq
MIRT2315701	hsa-miR-1321	CLIP-seq
MIRT2315702	hsa-miR-136	CLIP-seq
MIRT1306872	hsa-miR-137	CLIP-seq
MIRT2315703	hsa-miR-142-5p	CLIP-seq
MIRT2315704	hsa-miR-144	CLIP-seq
MIRT1306875	hsa-miR-200b	CLIP-seq
MIRT1306876	hsa-miR-200c	CLIP-seq
MIRT1306879	hsa-miR-2053	CLIP-seq
MIRT2315705	hsa-miR-2278	CLIP-seq
MIRT1306883	hsa-miR-297	CLIP-seq
MIRT2315706	hsa-miR-3138	CLIP-seq
MIRT1306887	hsa-miR-3148	CLIP-seq
MIRT2315707	hsa-miR-3158-3p	CLIP-seq
MIRT2315708	hsa-miR-3162-5p	CLIP-seq
MIRT2315709	hsa-miR-3187-3p	CLIP-seq
MIRT2315710	hsa-miR-3198	CLIP-seq
MIRT2315711	hsa-miR-324-5p	CLIP-seq
MIRT2315712	hsa-miR-340	CLIP-seq
MIRT1306891	hsa-miR-3613-3p	CLIP-seq
MIRT2315713	hsa-miR-3688-3p	CLIP-seq
MIRT1306897	hsa-miR-374c	CLIP-seq
MIRT2315714	hsa-miR-412	CLIP-seq
MIRT1306901	hsa-miR-4257	CLIP-seq
MIRT1306903	hsa-miR-429	CLIP-seq
MIRT2315715	hsa-miR-4294	CLIP-seq
MIRT1306906	hsa-miR-4307	CLIP-seq
MIRT2315716	hsa-miR-4309	CLIP-seq
MIRT2315717	hsa-miR-4311	CLIP-seq
MIRT2315718	hsa-miR-4435	CLIP-seq
MIRT2315719	hsa-miR-4446-3p	CLIP-seq
MIRT2315720	hsa-miR-4493	CLIP-seq
MIRT2315721	hsa-miR-4520a-3p	CLIP-seq
MIRT2315722	hsa-miR-4529-5p	CLIP-seq
MIRT2315723	hsa-miR-4643	CLIP-seq
MIRT2315724	hsa-miR-4645-3p	CLIP-seq
MIRT2315725	hsa-miR-4659a-3p	CLIP-seq
MIRT2315726	hsa-miR-4659b-3p	CLIP-seq
MIRT2315727	hsa-miR-466	CLIP-seq
MIRT2315728	hsa-miR-4666-5p	CLIP-seq
MIRT2315729	hsa-miR-4668-5p	CLIP-seq
MIRT2315730	hsa-miR-4691-5p	CLIP-seq
MIRT2315731	hsa-miR-4701-5p	CLIP-seq
MIRT2315732	hsa-miR-4720-3p	CLIP-seq
MIRT2315733	hsa-miR-4729	CLIP-seq
MIRT2315734	hsa-miR-4739	CLIP-seq
MIRT2315735	hsa-miR-4756-5p	CLIP-seq
MIRT2315736	hsa-miR-4789-3p	CLIP-seq
MIRT1306926	hsa-miR-4795-3p	CLIP-seq
MIRT1306933	hsa-miR-520g	CLIP-seq
MIRT2315737	hsa-miR-548a-3p	CLIP-seq
MIRT2315738	hsa-miR-548ae	CLIP-seq
MIRT2315739	hsa-miR-548aj	CLIP-seq
MIRT2315740	hsa-miR-548am	CLIP-seq
MIRT2315741	hsa-miR-548e	CLIP-seq
MIRT2315742	hsa-miR-548f	CLIP-seq
MIRT1306935	hsa-miR-548g	CLIP-seq
MIRT2315743	hsa-miR-548s	CLIP-seq
MIRT2315744	hsa-miR-548x	CLIP-seq
MIRT1306939	hsa-miR-567	CLIP-seq
MIRT2315745	hsa-miR-583	CLIP-seq
MIRT2315746	hsa-miR-586	CLIP-seq
MIRT2315747	hsa-miR-588	CLIP-seq
MIRT2315748	hsa-miR-625	CLIP-seq
MIRT1306947	hsa-miR-655	CLIP-seq
MIRT1306874	hsa-miR-185	CLIP-seq
MIRT1306886	hsa-miR-31	CLIP-seq
MIRT2315707	hsa-miR-3158-3p	CLIP-seq
MIRT1306905	hsa-miR-4306	CLIP-seq
MIRT1306916	hsa-miR-4644	CLIP-seq
MIRT2458240	hsa-miR-561	CLIP-seq
MIRT2458241	hsa-miR-624	CLIP-seq
MIRT2315700	hsa-miR-1289	CLIP-seq
MIRT2611862	hsa-miR-18a	CLIP-seq
MIRT2611863	hsa-miR-18b	CLIP-seq
MIRT2315710	hsa-miR-3198	CLIP-seq
MIRT1306892	hsa-miR-3620	CLIP-seq
MIRT2315715	hsa-miR-4294	CLIP-seq
MIRT1306906	hsa-miR-4307	CLIP-seq
MIRT2315716	hsa-miR-4309	CLIP-seq
MIRT1306911	hsa-miR-4477b	CLIP-seq
MIRT2611864	hsa-miR-4735-3p	CLIP-seq
MIRT2611865	hsa-miR-570	CLIP-seq
MIRT2611866	hsa-miR-875-5p	CLIP-seq
MIRT2611867	hsa-miR-934	CLIP-seq
MIRT2315700	hsa-miR-1289	CLIP-seq
MIRT2611862	hsa-miR-18a	CLIP-seq
MIRT2611863	hsa-miR-18b	CLIP-seq
MIRT2315710	hsa-miR-3198	CLIP-seq
MIRT1306892	hsa-miR-3620	CLIP-seq
MIRT2315715	hsa-miR-4294	CLIP-seq
MIRT1306906	hsa-miR-4307	CLIP-seq
MIRT2315716	hsa-miR-4309	CLIP-seq
MIRT1306911	hsa-miR-4477b	CLIP-seq
MIRT2611864	hsa-miR-4735-3p	CLIP-seq
MIRT2611865	hsa-miR-570	CLIP-seq
MIRT2611866	hsa-miR-875-5p	CLIP-seq
MIRT2611867	hsa-miR-934	CLIP-seq

Show/Hide all(16)

GO ID	Ontology	Definition	Evidence
GO:0000166	Function	Nucleotide binding	IEA
GO:0005524	Function	ATP binding	IEA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	ISS
GO:0005829	Component	Cytosol	TAS
GO:0009064	Process	Glutamine family amino acid metabolic process	IEA
GO:0009064	Process	Glutamine family amino acid metabolic process	TAS
GO:0016874	Function	Ligase activity	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0072590	Function	N-acetyl-L-aspartate-L-glutamate ligase activity	IBA
GO:0072590	Function	N-acetyl-L-aspartate-L-glutamate ligase activity	IEA
GO:0072590	Function	N-acetyl-L-aspartate-L-glutamate ligase activity	ISS
GO:0072590	Function	N-acetyl-L-aspartate-L-glutamate ligase activity	TAS
GO:0072591	Function	Citrate-L-glutamate ligase activity	IEA
GO:0072591	Function	Citrate-L-glutamate ligase activity	ISS

MIM	HGNC	e!Ensembl
614054	29228	ENSG00000166532

Protein

UniProt ID

Q9ULI2

Protein name

Beta-citrylglutamate synthase B (EC 6.3.1.17) (N-acetyl-aspartylglutamate synthetase B) (NAAG synthetase B) (NAAGS) (EC 6.3.2.41) (Ribosomal protein S6 modification-like protein B)

Protein function

Catalyzes the synthesis of beta-citryl-L-glutamate and N-acetyl-L-aspartyl-L-glutamate. Beta-citryl-L-glutamate is synthesized more efficiently than N-acetyl-L-aspartyl-L-glutamate.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF08443	RimK	112 → 303	RimK-like ATP-grasp domain	Domain

Sequence

MCSSVAAKLWFLTDRRIREDYPQKEILRALKAKCCEEELDFRAVVMDEVVLTIEQGNLGL
RINGELITAYPQVVVVRVPTPWVQSDSDITVLRHLEKMGCRLMNRPQAILNCVNKFWTFQ
ELAGHGVPLPDTFSYGGHENFAKMIDEAEVLEFPMVVKNTRGHRGKAVFLARDKHHLADL
SHLIRHEAPYLFQKYVKESHGRDVRVIVVGGRVVGTMLRCSTDGRMQSNCSLGGVGMMCS
LSEQGKQLAIQVSNILGMDVCGIDLLMKDDGSFCVCEANANVGFIAFDKACNLDVAGIIA
DYAASLLPSGRLTRRMSLLSVVSTASETSEPELGPPASTAVDNMSASSSSVDSDPESTER
ELLTKLPGGLFNMNQLLANEIKLLVD

Sequence length

386

Interactions

View interactions

Show/Hide Unknown Diseases (2)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Hypertension	Hypertension (confirmatory factor analysis Factor 12)	N/A	N/A	GWAS
Oligodendroglioma	Oligodendroglioma	N/A	N/A	GWAS

Show/Hide Text Mining Associations (2)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Colonic Neoplasms	Associate	35712285, 36181111
Colorectal Neoplasms	Associate	38167072, 38466182

RIMKLB (ribosomal modification protein rimK like family member B)