PTPRF (protein tyrosine phosphatase receptor type F)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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5792 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Protein tyrosine phosphatase receptor type F |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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PTPRF |
Synonyms (NCBI Gene)
Gene synonyms aliases
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BNAH2, LAR |
Disease Acronyms (UniProt)
Disease acronyms from UniProt database
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BNAH2 |
Chromosome
Chromosome number
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1 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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1p34.2 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic tran |
SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
UniProt ID | P10586 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Protein name | Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) (Leukocyte common antigen related) (LAR) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Protein function | Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase) and dephosphorylates EPHA2 regulating its activity.; The first PTPase domain has enzymatic activity, while the second one seems t | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
PDB | 1LAR , 2DJU , 2DN7 , 2EDX , 2EDY , 2YD5 , 2YD8 , 4N5U , 6KR4 , 6TPT , 6TPU , 6TPV , 6TPW | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Family and domains |
Pfam
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Sequence | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sequence length | 1907 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Interactions | View interactions |
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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