Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs Transcription factors Other IDs Associated diseases
Entrez ID	5770
Gene name	Protein tyrosine phosphatase non-receptor type 1
Gene symbol	PTPN1
Synonyms (NCBI Gene)	PTP1B
Chromosome	20
Chromosome location	20q13.13
Summary	The protein encoded by this gene is the founding member of the protein tyrosine phosphatase (PTP) family, which was isolated and identified based on its enzymatic activity and amino acid sequence. PTPs catalyze the hydrolysis of the phosphate monoesters s

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SNP ID	Visualize variation	Clinical significance	Consequence
rs16989673	->G	Risk-factor	3 prime UTR variant

714

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miRTarBase ID	miRNA	Experiments	Reference
MIRT003154	hsa-miR-210-3p	2DGEimmunoprecipitaionLuciferase reporter assayMass spectrometryMicroarrayqRT-PCRWestern blot	19826008
MIRT007007	hsa-miR-122-5p	Luciferase reporter assay	22807119
MIRT007351	hsa-miR-362-3p	Western blot	23280316
MIRT007351	hsa-miR-362-3p	Western blot	23280316
MIRT007351	hsa-miR-362-3p	Western blot	23280316
MIRT007351	hsa-miR-362-3p	Western blot	23280316
MIRT019939	hsa-miR-375	Microarray	20215506
MIRT023987	hsa-miR-1-3p	Proteomics	18668040
MIRT029981	hsa-miR-26b-5p	Microarray	19088304
MIRT756270	hsa-miR-135a-5p	Luciferase reporter assayWestern blottingqRT-PCR	35610725
MIRT756299	hsa-miR-125a-5p	Luciferase reporter assayImmunofluorescence	35401562
MIRT1274644	hsa-miR-1	CLIP-seq
MIRT1274645	hsa-miR-1179	CLIP-seq
MIRT1274646	hsa-miR-1185	CLIP-seq
MIRT1274647	hsa-miR-1206	CLIP-seq
MIRT1274648	hsa-miR-122	CLIP-seq
MIRT1274649	hsa-miR-1226	CLIP-seq
MIRT1274650	hsa-miR-1229	CLIP-seq
MIRT1274651	hsa-miR-1236	CLIP-seq
MIRT1274652	hsa-miR-1246	CLIP-seq
MIRT1274653	hsa-miR-1257	CLIP-seq
MIRT1274654	hsa-miR-1273g	CLIP-seq
MIRT1274655	hsa-miR-129-3p	CLIP-seq
MIRT1274656	hsa-miR-1294	CLIP-seq
MIRT1274657	hsa-miR-130a	CLIP-seq
MIRT1274658	hsa-miR-130b	CLIP-seq
MIRT1274659	hsa-miR-1321	CLIP-seq
MIRT1274660	hsa-miR-135a	CLIP-seq
MIRT1274661	hsa-miR-135b	CLIP-seq
MIRT1274662	hsa-miR-140-3p	CLIP-seq
MIRT1274663	hsa-miR-146a	CLIP-seq
MIRT1274664	hsa-miR-146b-5p	CLIP-seq
MIRT1274665	hsa-miR-185	CLIP-seq
MIRT1274666	hsa-miR-1908	CLIP-seq
MIRT1274667	hsa-miR-198	CLIP-seq
MIRT1274668	hsa-miR-203	CLIP-seq
MIRT1274669	hsa-miR-206	CLIP-seq
MIRT1274670	hsa-miR-2110	CLIP-seq
MIRT1274671	hsa-miR-214	CLIP-seq
MIRT1274672	hsa-miR-216a	CLIP-seq
MIRT1274673	hsa-miR-216b	CLIP-seq
MIRT1274674	hsa-miR-224	CLIP-seq
MIRT1274675	hsa-miR-2467-3p	CLIP-seq
MIRT1274676	hsa-miR-28-3p	CLIP-seq
MIRT1274677	hsa-miR-2861	CLIP-seq
MIRT1274678	hsa-miR-298	CLIP-seq
MIRT1274679	hsa-miR-299-5p	CLIP-seq
MIRT1274680	hsa-miR-301a	CLIP-seq
MIRT1274681	hsa-miR-301b	CLIP-seq
MIRT1274682	hsa-miR-3120-3p	CLIP-seq
MIRT1274683	hsa-miR-3146	CLIP-seq
MIRT1274684	hsa-miR-3148	CLIP-seq
MIRT1274685	hsa-miR-3150a-3p	CLIP-seq
MIRT1274686	hsa-miR-3161	CLIP-seq
MIRT1274687	hsa-miR-3180	CLIP-seq
MIRT1274688	hsa-miR-3180-3p	CLIP-seq
MIRT1274689	hsa-miR-3180-5p	CLIP-seq
MIRT1274690	hsa-miR-3183	CLIP-seq
MIRT1274691	hsa-miR-3184	CLIP-seq
MIRT1274692	hsa-miR-3187-3p	CLIP-seq
MIRT1274693	hsa-miR-3194-3p	CLIP-seq
MIRT1274694	hsa-miR-3196	CLIP-seq
MIRT1274695	hsa-miR-323-3p	CLIP-seq
MIRT1274696	hsa-miR-329	CLIP-seq
MIRT1274697	hsa-miR-338-3p	CLIP-seq
MIRT1274698	hsa-miR-338-5p	CLIP-seq
MIRT1274699	hsa-miR-342-3p	CLIP-seq
MIRT1274700	hsa-miR-34c-3p	CLIP-seq
MIRT1274701	hsa-miR-3591-5p	CLIP-seq
MIRT1274702	hsa-miR-3605-5p	CLIP-seq
MIRT1274703	hsa-miR-3613-3p	CLIP-seq
MIRT1274704	hsa-miR-3614-3p	CLIP-seq
MIRT1274705	hsa-miR-3619-5p	CLIP-seq
MIRT1274706	hsa-miR-3661	CLIP-seq
MIRT1274707	hsa-miR-3665	CLIP-seq
MIRT1274708	hsa-miR-3666	CLIP-seq
MIRT1274709	hsa-miR-3667-5p	CLIP-seq
MIRT1274710	hsa-miR-3673	CLIP-seq
MIRT1274711	hsa-miR-3679-5p	CLIP-seq
MIRT1274712	hsa-miR-370	CLIP-seq
MIRT1274713	hsa-miR-371b-5p	CLIP-seq
MIRT1274714	hsa-miR-374c	CLIP-seq
MIRT1274715	hsa-miR-380	CLIP-seq
MIRT1274716	hsa-miR-3913-3p	CLIP-seq
MIRT1274717	hsa-miR-3914	CLIP-seq
MIRT1274718	hsa-miR-3929	CLIP-seq
MIRT1274719	hsa-miR-3941	CLIP-seq
MIRT1274720	hsa-miR-423-5p	CLIP-seq
MIRT1274721	hsa-miR-4260	CLIP-seq
MIRT1274722	hsa-miR-4266	CLIP-seq
MIRT1274723	hsa-miR-4267	CLIP-seq
MIRT1274724	hsa-miR-4270	CLIP-seq
MIRT1274725	hsa-miR-4271	CLIP-seq
MIRT1274726	hsa-miR-4273	CLIP-seq
MIRT1274727	hsa-miR-4279	CLIP-seq
MIRT1274728	hsa-miR-4282	CLIP-seq
MIRT1274729	hsa-miR-4291	CLIP-seq
MIRT1274730	hsa-miR-4295	CLIP-seq
MIRT1274731	hsa-miR-4297	CLIP-seq
MIRT1274732	hsa-miR-4306	CLIP-seq
MIRT1274733	hsa-miR-4417	CLIP-seq
MIRT1274734	hsa-miR-4419b	CLIP-seq
MIRT1274735	hsa-miR-4424	CLIP-seq
MIRT1274736	hsa-miR-4426	CLIP-seq
MIRT1274737	hsa-miR-4436a	CLIP-seq
MIRT1274738	hsa-miR-4437	CLIP-seq
MIRT1274739	hsa-miR-4438	CLIP-seq
MIRT1274740	hsa-miR-4441	CLIP-seq
MIRT1274741	hsa-miR-4447	CLIP-seq
MIRT1274742	hsa-miR-4461	CLIP-seq
MIRT1274743	hsa-miR-4470	CLIP-seq
MIRT1274744	hsa-miR-4472	CLIP-seq
MIRT1274745	hsa-miR-4473	CLIP-seq
MIRT1274746	hsa-miR-4477a	CLIP-seq
MIRT1274747	hsa-miR-4478	CLIP-seq
MIRT1274748	hsa-miR-4488	CLIP-seq
MIRT1274749	hsa-miR-4502	CLIP-seq
MIRT1274750	hsa-miR-4505	CLIP-seq
MIRT1274751	hsa-miR-4519	CLIP-seq
MIRT1274752	hsa-miR-451b	CLIP-seq
MIRT1274753	hsa-miR-4528	CLIP-seq
MIRT1274754	hsa-miR-4529-5p	CLIP-seq
MIRT1274755	hsa-miR-4530	CLIP-seq
MIRT1274756	hsa-miR-454	CLIP-seq
MIRT1274757	hsa-miR-4639-3p	CLIP-seq
MIRT1274758	hsa-miR-4641	CLIP-seq
MIRT1274759	hsa-miR-4644	CLIP-seq
MIRT1274760	hsa-miR-4647	CLIP-seq
MIRT1274761	hsa-miR-4662b	CLIP-seq
MIRT1274762	hsa-miR-4668-5p	CLIP-seq
MIRT1274763	hsa-miR-4671-3p	CLIP-seq
MIRT1274764	hsa-miR-4674	CLIP-seq
MIRT1274765	hsa-miR-4677-5p	CLIP-seq
MIRT1274766	hsa-miR-4682	CLIP-seq
MIRT1274767	hsa-miR-4687-3p	CLIP-seq
MIRT1274768	hsa-miR-4690-5p	CLIP-seq
MIRT1274769	hsa-miR-4695-5p	CLIP-seq
MIRT1274770	hsa-miR-4696	CLIP-seq
MIRT1274771	hsa-miR-4697-5p	CLIP-seq
MIRT1274772	hsa-miR-4700-3p	CLIP-seq
MIRT1274773	hsa-miR-4708-3p	CLIP-seq
MIRT1274774	hsa-miR-4712-5p	CLIP-seq
MIRT1274775	hsa-miR-4718	CLIP-seq
MIRT1274776	hsa-miR-4720-3p	CLIP-seq
MIRT1274777	hsa-miR-4723-3p	CLIP-seq
MIRT1274778	hsa-miR-4723-5p	CLIP-seq
MIRT1274779	hsa-miR-4725-3p	CLIP-seq
MIRT1274780	hsa-miR-4725-5p	CLIP-seq
MIRT1274781	hsa-miR-4733-3p	CLIP-seq
MIRT1274782	hsa-miR-4733-5p	CLIP-seq
MIRT1274783	hsa-miR-4734	CLIP-seq
MIRT1274784	hsa-miR-4739	CLIP-seq
MIRT1274785	hsa-miR-4752	CLIP-seq
MIRT1274786	hsa-miR-4753-3p	CLIP-seq
MIRT1274787	hsa-miR-4755-3p	CLIP-seq
MIRT1274788	hsa-miR-4756-3p	CLIP-seq
MIRT1274789	hsa-miR-4756-5p	CLIP-seq
MIRT1274790	hsa-miR-4767	CLIP-seq
MIRT1274791	hsa-miR-4779	CLIP-seq
MIRT1274792	hsa-miR-4780	CLIP-seq
MIRT1274793	hsa-miR-4789-5p	CLIP-seq
MIRT1274794	hsa-miR-4795-3p	CLIP-seq
MIRT1274795	hsa-miR-489	CLIP-seq
MIRT1274796	hsa-miR-498	CLIP-seq
MIRT1274797	hsa-miR-504	CLIP-seq
MIRT1274798	hsa-miR-515-5p	CLIP-seq
MIRT1274799	hsa-miR-520a-5p	CLIP-seq
MIRT1274800	hsa-miR-520g	CLIP-seq
MIRT1274801	hsa-miR-520h	CLIP-seq
MIRT1274802	hsa-miR-525-5p	CLIP-seq
MIRT1274803	hsa-miR-532-5p	CLIP-seq
MIRT1274804	hsa-miR-544b	CLIP-seq
MIRT1274805	hsa-miR-545	CLIP-seq
MIRT1274806	hsa-miR-548ac	CLIP-seq
MIRT1274807	hsa-miR-548ae	CLIP-seq
MIRT1274808	hsa-miR-548aj	CLIP-seq
MIRT1274809	hsa-miR-548am	CLIP-seq
MIRT1274810	hsa-miR-548d-3p	CLIP-seq
MIRT1274811	hsa-miR-548h	CLIP-seq
MIRT1274812	hsa-miR-548j	CLIP-seq
MIRT1274813	hsa-miR-548x	CLIP-seq
MIRT1274814	hsa-miR-548z	CLIP-seq
MIRT1274815	hsa-miR-561	CLIP-seq
MIRT1274816	hsa-miR-580	CLIP-seq
MIRT1274817	hsa-miR-589	CLIP-seq
MIRT1274818	hsa-miR-590-3p	CLIP-seq
MIRT1274819	hsa-miR-595	CLIP-seq
MIRT1274820	hsa-miR-603	CLIP-seq
MIRT1274821	hsa-miR-606	CLIP-seq
MIRT1274822	hsa-miR-613	CLIP-seq
MIRT1274823	hsa-miR-617	CLIP-seq
MIRT1274824	hsa-miR-629	CLIP-seq
MIRT1274825	hsa-miR-631	CLIP-seq
MIRT1274826	hsa-miR-654-3p	CLIP-seq
MIRT1274827	hsa-miR-655	CLIP-seq
MIRT1274828	hsa-miR-656	CLIP-seq
MIRT1274829	hsa-miR-659	CLIP-seq
MIRT1274830	hsa-miR-662	CLIP-seq
MIRT1274831	hsa-miR-663	CLIP-seq
MIRT1274832	hsa-miR-760	CLIP-seq
MIRT1274833	hsa-miR-761	CLIP-seq
MIRT1274834	hsa-miR-764	CLIP-seq
MIRT1274835	hsa-miR-765	CLIP-seq
MIRT1274836	hsa-miR-770-5p	CLIP-seq
MIRT1274837	hsa-miR-939	CLIP-seq
MIRT1274838	hsa-miR-942	CLIP-seq
MIRT1274644	hsa-miR-1	CLIP-seq
MIRT2080797	hsa-miR-105	CLIP-seq
MIRT2080798	hsa-miR-1197	CLIP-seq
MIRT1274648	hsa-miR-122	CLIP-seq
MIRT2080799	hsa-miR-1228	CLIP-seq
MIRT1274650	hsa-miR-1229	CLIP-seq
MIRT1274651	hsa-miR-1236	CLIP-seq
MIRT1274653	hsa-miR-1257	CLIP-seq
MIRT2080800	hsa-miR-1260	CLIP-seq
MIRT2080801	hsa-miR-1260b	CLIP-seq
MIRT2080802	hsa-miR-1268	CLIP-seq
MIRT2080803	hsa-miR-1268b	CLIP-seq
MIRT2080804	hsa-miR-1269	CLIP-seq
MIRT2080805	hsa-miR-1269b	CLIP-seq
MIRT2080806	hsa-miR-1273c	CLIP-seq
MIRT1274654	hsa-miR-1273g	CLIP-seq
MIRT2080807	hsa-miR-1278	CLIP-seq
MIRT1274656	hsa-miR-1294	CLIP-seq
MIRT1274657	hsa-miR-130a	CLIP-seq
MIRT1274658	hsa-miR-130b	CLIP-seq
MIRT1274660	hsa-miR-135a	CLIP-seq
MIRT1274661	hsa-miR-135b	CLIP-seq
MIRT2080808	hsa-miR-137	CLIP-seq
MIRT1274662	hsa-miR-140-3p	CLIP-seq
MIRT1274663	hsa-miR-146a	CLIP-seq
MIRT1274664	hsa-miR-146b-5p	CLIP-seq
MIRT2080809	hsa-miR-188-3p	CLIP-seq
MIRT2080810	hsa-miR-193a-3p	CLIP-seq
MIRT2080811	hsa-miR-193b	CLIP-seq
MIRT1274668	hsa-miR-203	CLIP-seq
MIRT1274669	hsa-miR-206	CLIP-seq
MIRT1274671	hsa-miR-214	CLIP-seq
MIRT1274672	hsa-miR-216a	CLIP-seq
MIRT1274673	hsa-miR-216b	CLIP-seq
MIRT1274675	hsa-miR-2467-3p	CLIP-seq
MIRT1274676	hsa-miR-28-3p	CLIP-seq
MIRT1274680	hsa-miR-301a	CLIP-seq
MIRT1274681	hsa-miR-301b	CLIP-seq
MIRT2080812	hsa-miR-3130-3p	CLIP-seq
MIRT2080813	hsa-miR-3156-3p	CLIP-seq
MIRT1274689	hsa-miR-3180-5p	CLIP-seq
MIRT1274690	hsa-miR-3183	CLIP-seq
MIRT1274693	hsa-miR-3194-3p	CLIP-seq
MIRT1274696	hsa-miR-329	CLIP-seq
MIRT1274697	hsa-miR-338-3p	CLIP-seq
MIRT1274698	hsa-miR-338-5p	CLIP-seq
MIRT1274699	hsa-miR-342-3p	CLIP-seq
MIRT1274700	hsa-miR-34c-3p	CLIP-seq
MIRT1274701	hsa-miR-3591-5p	CLIP-seq
MIRT1274705	hsa-miR-3619-5p	CLIP-seq
MIRT2080814	hsa-miR-3663-5p	CLIP-seq
MIRT1274707	hsa-miR-3665	CLIP-seq
MIRT1274708	hsa-miR-3666	CLIP-seq
MIRT2080815	hsa-miR-3667-3p	CLIP-seq
MIRT1274709	hsa-miR-3667-5p	CLIP-seq
MIRT1274710	hsa-miR-3673	CLIP-seq
MIRT2080816	hsa-miR-3675-5p	CLIP-seq
MIRT1274714	hsa-miR-374c	CLIP-seq
MIRT1274719	hsa-miR-3941	CLIP-seq
MIRT1274722	hsa-miR-4266	CLIP-seq
MIRT1274725	hsa-miR-4271	CLIP-seq
MIRT1274726	hsa-miR-4273	CLIP-seq
MIRT1274730	hsa-miR-4295	CLIP-seq
MIRT1274733	hsa-miR-4417	CLIP-seq
MIRT2080817	hsa-miR-4423-3p	CLIP-seq
MIRT1274735	hsa-miR-4424	CLIP-seq
MIRT1274736	hsa-miR-4426	CLIP-seq
MIRT1274737	hsa-miR-4436a	CLIP-seq
MIRT1274738	hsa-miR-4437	CLIP-seq
MIRT1274745	hsa-miR-4473	CLIP-seq
MIRT1274746	hsa-miR-4477a	CLIP-seq
MIRT2080818	hsa-miR-4514	CLIP-seq
MIRT1274752	hsa-miR-451b	CLIP-seq
MIRT2080819	hsa-miR-4520a-3p	CLIP-seq
MIRT2080820	hsa-miR-4520b-3p	CLIP-seq
MIRT2080821	hsa-miR-4527	CLIP-seq
MIRT2080822	hsa-miR-4529-3p	CLIP-seq
MIRT1274755	hsa-miR-4530	CLIP-seq
MIRT1274756	hsa-miR-454	CLIP-seq
MIRT1274760	hsa-miR-4647	CLIP-seq
MIRT1274761	hsa-miR-4662b	CLIP-seq
MIRT2080823	hsa-miR-4663	CLIP-seq
MIRT2080824	hsa-miR-4666-5p	CLIP-seq
MIRT1274763	hsa-miR-4671-3p	CLIP-seq
MIRT1274764	hsa-miR-4674	CLIP-seq
MIRT1274765	hsa-miR-4677-5p	CLIP-seq
MIRT1274766	hsa-miR-4682	CLIP-seq
MIRT2080825	hsa-miR-4684-5p	CLIP-seq
MIRT2080826	hsa-miR-4692	CLIP-seq
MIRT1274769	hsa-miR-4695-5p	CLIP-seq
MIRT1274770	hsa-miR-4696	CLIP-seq
MIRT1274772	hsa-miR-4700-3p	CLIP-seq
MIRT1274774	hsa-miR-4712-5p	CLIP-seq
MIRT1274777	hsa-miR-4723-3p	CLIP-seq
MIRT1274778	hsa-miR-4723-5p	CLIP-seq
MIRT1274779	hsa-miR-4725-3p	CLIP-seq
MIRT1274780	hsa-miR-4725-5p	CLIP-seq
MIRT2080827	hsa-miR-4731-3p	CLIP-seq
MIRT1274783	hsa-miR-4734	CLIP-seq
MIRT2080828	hsa-miR-4736	CLIP-seq
MIRT2080829	hsa-miR-4750	CLIP-seq
MIRT1274788	hsa-miR-4756-3p	CLIP-seq
MIRT1274790	hsa-miR-4767	CLIP-seq
MIRT2080830	hsa-miR-4768-5p	CLIP-seq
MIRT1274791	hsa-miR-4779	CLIP-seq
MIRT1274793	hsa-miR-4789-5p	CLIP-seq
MIRT2080831	hsa-miR-4801	CLIP-seq
MIRT2080832	hsa-miR-4803	CLIP-seq
MIRT2080833	hsa-miR-486-3p	CLIP-seq
MIRT1274796	hsa-miR-498	CLIP-seq
MIRT1274797	hsa-miR-504	CLIP-seq
MIRT1274800	hsa-miR-520g	CLIP-seq
MIRT1274801	hsa-miR-520h	CLIP-seq
MIRT2080834	hsa-miR-548a-3p	CLIP-seq
MIRT1274806	hsa-miR-548ac	CLIP-seq
MIRT1274807	hsa-miR-548ae	CLIP-seq
MIRT1274808	hsa-miR-548aj	CLIP-seq
MIRT1274809	hsa-miR-548am	CLIP-seq
MIRT1274810	hsa-miR-548d-3p	CLIP-seq
MIRT2080835	hsa-miR-548e	CLIP-seq
MIRT2080836	hsa-miR-548f	CLIP-seq
MIRT1274811	hsa-miR-548h	CLIP-seq
MIRT1274812	hsa-miR-548j	CLIP-seq
MIRT1274813	hsa-miR-548x	CLIP-seq
MIRT1274814	hsa-miR-548z	CLIP-seq
MIRT1274815	hsa-miR-561	CLIP-seq
MIRT2080837	hsa-miR-576-5p	CLIP-seq
MIRT2080838	hsa-miR-586	CLIP-seq
MIRT1274817	hsa-miR-589	CLIP-seq
MIRT1274819	hsa-miR-595	CLIP-seq
MIRT2080839	hsa-miR-600	CLIP-seq
MIRT2080840	hsa-miR-602	CLIP-seq
MIRT1274820	hsa-miR-603	CLIP-seq
MIRT1274821	hsa-miR-606	CLIP-seq
MIRT1274822	hsa-miR-613	CLIP-seq
MIRT1274823	hsa-miR-617	CLIP-seq
MIRT2080841	hsa-miR-628-5p	CLIP-seq
MIRT1274824	hsa-miR-629	CLIP-seq
MIRT1274826	hsa-miR-654-3p	CLIP-seq
MIRT1274827	hsa-miR-655	CLIP-seq
MIRT2080842	hsa-miR-657	CLIP-seq
MIRT1274832	hsa-miR-760	CLIP-seq
MIRT1274833	hsa-miR-761	CLIP-seq
MIRT1274834	hsa-miR-764	CLIP-seq
MIRT1274835	hsa-miR-765	CLIP-seq
MIRT2080843	hsa-miR-767-3p	CLIP-seq
MIRT1274836	hsa-miR-770-5p	CLIP-seq
MIRT2080844	hsa-miR-890	CLIP-seq
MIRT2080845	hsa-miR-892b	CLIP-seq
MIRT2080846	hsa-miR-940	CLIP-seq
MIRT1274838	hsa-miR-942	CLIP-seq
MIRT1274644	hsa-miR-1	CLIP-seq
MIRT1274645	hsa-miR-1179	CLIP-seq
MIRT1274646	hsa-miR-1185	CLIP-seq
MIRT2080798	hsa-miR-1197	CLIP-seq
MIRT1274647	hsa-miR-1206	CLIP-seq
MIRT1274649	hsa-miR-1226	CLIP-seq
MIRT1274650	hsa-miR-1229	CLIP-seq
MIRT2306834	hsa-miR-124	CLIP-seq
MIRT1274652	hsa-miR-1246	CLIP-seq
MIRT1274653	hsa-miR-1257	CLIP-seq
MIRT2306835	hsa-miR-1263	CLIP-seq
MIRT2080804	hsa-miR-1269	CLIP-seq
MIRT2080805	hsa-miR-1269b	CLIP-seq
MIRT2080806	hsa-miR-1273c	CLIP-seq
MIRT2080807	hsa-miR-1278	CLIP-seq
MIRT2306836	hsa-miR-1286	CLIP-seq
MIRT2306837	hsa-miR-1290	CLIP-seq
MIRT1274655	hsa-miR-129-3p	CLIP-seq
MIRT1274656	hsa-miR-1294	CLIP-seq
MIRT1274657	hsa-miR-130a	CLIP-seq
MIRT1274658	hsa-miR-130b	CLIP-seq
MIRT1274659	hsa-miR-1321	CLIP-seq
MIRT1274660	hsa-miR-135a	CLIP-seq
MIRT1274661	hsa-miR-135b	CLIP-seq
MIRT1274662	hsa-miR-140-3p	CLIP-seq
MIRT1274663	hsa-miR-146a	CLIP-seq
MIRT1274664	hsa-miR-146b-5p	CLIP-seq
MIRT1274665	hsa-miR-185	CLIP-seq
MIRT1274666	hsa-miR-1908	CLIP-seq
MIRT2306838	hsa-miR-194	CLIP-seq
MIRT1274667	hsa-miR-198	CLIP-seq
MIRT1274668	hsa-miR-203	CLIP-seq
MIRT2306839	hsa-miR-204	CLIP-seq
MIRT1274669	hsa-miR-206	CLIP-seq
MIRT2306840	hsa-miR-211	CLIP-seq
MIRT2306841	hsa-miR-2115	CLIP-seq
MIRT1274671	hsa-miR-214	CLIP-seq
MIRT1274672	hsa-miR-216a	CLIP-seq
MIRT1274673	hsa-miR-216b	CLIP-seq
MIRT1274674	hsa-miR-224	CLIP-seq
MIRT1274675	hsa-miR-2467-3p	CLIP-seq
MIRT1274677	hsa-miR-2861	CLIP-seq
MIRT2306842	hsa-miR-29a	CLIP-seq
MIRT2306843	hsa-miR-29b	CLIP-seq
MIRT2306844	hsa-miR-29c	CLIP-seq
MIRT1274680	hsa-miR-301a	CLIP-seq
MIRT1274681	hsa-miR-301b	CLIP-seq
MIRT2306845	hsa-miR-3121-5p	CLIP-seq
MIRT1274683	hsa-miR-3146	CLIP-seq
MIRT2306846	hsa-miR-3158-5p	CLIP-seq
MIRT1274686	hsa-miR-3161	CLIP-seq
MIRT2306847	hsa-miR-3167	CLIP-seq
MIRT2306848	hsa-miR-3179	CLIP-seq
MIRT1274687	hsa-miR-3180	CLIP-seq
MIRT1274688	hsa-miR-3180-3p	CLIP-seq
MIRT1274690	hsa-miR-3183	CLIP-seq
MIRT1274692	hsa-miR-3187-3p	CLIP-seq
MIRT2306849	hsa-miR-3190	CLIP-seq
MIRT1274693	hsa-miR-3194-3p	CLIP-seq
MIRT1274694	hsa-miR-3196	CLIP-seq
MIRT2306850	hsa-miR-3202	CLIP-seq
MIRT1274695	hsa-miR-323-3p	CLIP-seq
MIRT1274696	hsa-miR-329	CLIP-seq
MIRT1274698	hsa-miR-338-5p	CLIP-seq
MIRT1274699	hsa-miR-342-3p	CLIP-seq
MIRT1274700	hsa-miR-34c-3p	CLIP-seq
MIRT1274702	hsa-miR-3605-5p	CLIP-seq
MIRT1274704	hsa-miR-3614-3p	CLIP-seq
MIRT1274705	hsa-miR-3619-5p	CLIP-seq
MIRT2306851	hsa-miR-3657	CLIP-seq
MIRT1274706	hsa-miR-3661	CLIP-seq
MIRT2306852	hsa-miR-3663-3p	CLIP-seq
MIRT2080814	hsa-miR-3663-5p	CLIP-seq
MIRT1274708	hsa-miR-3666	CLIP-seq
MIRT2080815	hsa-miR-3667-3p	CLIP-seq
MIRT1274710	hsa-miR-3673	CLIP-seq
MIRT2080816	hsa-miR-3675-5p	CLIP-seq
MIRT1274711	hsa-miR-3679-5p	CLIP-seq
MIRT2306853	hsa-miR-3691-5p	CLIP-seq
MIRT2306854	hsa-miR-3714	CLIP-seq
MIRT1274714	hsa-miR-374c	CLIP-seq
MIRT1274715	hsa-miR-380	CLIP-seq
MIRT2306855	hsa-miR-383	CLIP-seq
MIRT2306856	hsa-miR-3910	CLIP-seq
MIRT1274717	hsa-miR-3914	CLIP-seq
MIRT1274719	hsa-miR-3941	CLIP-seq
MIRT1274722	hsa-miR-4266	CLIP-seq
MIRT1274724	hsa-miR-4270	CLIP-seq
MIRT1274726	hsa-miR-4273	CLIP-seq
MIRT1274728	hsa-miR-4282	CLIP-seq
MIRT1274729	hsa-miR-4291	CLIP-seq
MIRT1274730	hsa-miR-4295	CLIP-seq
MIRT1274731	hsa-miR-4297	CLIP-seq
MIRT1274732	hsa-miR-4306	CLIP-seq
MIRT2080817	hsa-miR-4423-3p	CLIP-seq
MIRT1274737	hsa-miR-4436a	CLIP-seq
MIRT1274739	hsa-miR-4438	CLIP-seq
MIRT1274740	hsa-miR-4441	CLIP-seq
MIRT1274742	hsa-miR-4461	CLIP-seq
MIRT1274743	hsa-miR-4470	CLIP-seq
MIRT1274746	hsa-miR-4477a	CLIP-seq
MIRT1274748	hsa-miR-4488	CLIP-seq
MIRT1274749	hsa-miR-4502	CLIP-seq
MIRT1274750	hsa-miR-4505	CLIP-seq
MIRT2080818	hsa-miR-4514	CLIP-seq
MIRT1274751	hsa-miR-4519	CLIP-seq
MIRT2080819	hsa-miR-4520a-3p	CLIP-seq
MIRT2080820	hsa-miR-4520b-3p	CLIP-seq
MIRT2080821	hsa-miR-4527	CLIP-seq
MIRT1274753	hsa-miR-4528	CLIP-seq
MIRT2080822	hsa-miR-4529-3p	CLIP-seq
MIRT1274754	hsa-miR-4529-5p	CLIP-seq
MIRT2306857	hsa-miR-4533	CLIP-seq
MIRT1274756	hsa-miR-454	CLIP-seq
MIRT1274758	hsa-miR-4641	CLIP-seq
MIRT1274759	hsa-miR-4644	CLIP-seq
MIRT2080824	hsa-miR-4666-5p	CLIP-seq
MIRT1274763	hsa-miR-4671-3p	CLIP-seq
MIRT1274765	hsa-miR-4677-5p	CLIP-seq
MIRT2306858	hsa-miR-4688	CLIP-seq
MIRT1274768	hsa-miR-4690-5p	CLIP-seq
MIRT2080826	hsa-miR-4692	CLIP-seq
MIRT1274769	hsa-miR-4695-5p	CLIP-seq
MIRT1274771	hsa-miR-4697-5p	CLIP-seq
MIRT1274772	hsa-miR-4700-3p	CLIP-seq
MIRT1274774	hsa-miR-4712-5p	CLIP-seq
MIRT1274776	hsa-miR-4720-3p	CLIP-seq
MIRT2306859	hsa-miR-4722-5p	CLIP-seq
MIRT1274777	hsa-miR-4723-3p	CLIP-seq
MIRT1274778	hsa-miR-4723-5p	CLIP-seq
MIRT2080827	hsa-miR-4731-3p	CLIP-seq
MIRT1274781	hsa-miR-4733-3p	CLIP-seq
MIRT1274783	hsa-miR-4734	CLIP-seq
MIRT2080828	hsa-miR-4736	CLIP-seq
MIRT1274784	hsa-miR-4739	CLIP-seq
MIRT1274785	hsa-miR-4752	CLIP-seq
MIRT1274787	hsa-miR-4755-3p	CLIP-seq
MIRT2306860	hsa-miR-4755-5p	CLIP-seq
MIRT1274788	hsa-miR-4756-3p	CLIP-seq
MIRT1274789	hsa-miR-4756-5p	CLIP-seq
MIRT2306861	hsa-miR-4761-5p	CLIP-seq
MIRT1274790	hsa-miR-4767	CLIP-seq
MIRT2306862	hsa-miR-4772-5p	CLIP-seq
MIRT1274791	hsa-miR-4779	CLIP-seq
MIRT1274792	hsa-miR-4780	CLIP-seq
MIRT1274794	hsa-miR-4795-3p	CLIP-seq
MIRT2306863	hsa-miR-4796-3p	CLIP-seq
MIRT2080831	hsa-miR-4801	CLIP-seq
MIRT2080832	hsa-miR-4803	CLIP-seq
MIRT2080833	hsa-miR-486-3p	CLIP-seq
MIRT1274796	hsa-miR-498	CLIP-seq
MIRT2306864	hsa-miR-506	CLIP-seq
MIRT2306865	hsa-miR-516a-3p	CLIP-seq
MIRT1274799	hsa-miR-520a-5p	CLIP-seq
MIRT1274800	hsa-miR-520g	CLIP-seq
MIRT1274801	hsa-miR-520h	CLIP-seq
MIRT1274802	hsa-miR-525-5p	CLIP-seq
MIRT1274804	hsa-miR-544b	CLIP-seq
MIRT1274805	hsa-miR-545	CLIP-seq
MIRT2080834	hsa-miR-548a-3p	CLIP-seq
MIRT2080835	hsa-miR-548e	CLIP-seq
MIRT2080836	hsa-miR-548f	CLIP-seq
MIRT1274811	hsa-miR-548h	CLIP-seq
MIRT1274812	hsa-miR-548j	CLIP-seq
MIRT2306866	hsa-miR-548n	CLIP-seq
MIRT1274815	hsa-miR-561	CLIP-seq
MIRT2080837	hsa-miR-576-5p	CLIP-seq
MIRT1274816	hsa-miR-580	CLIP-seq
MIRT2080838	hsa-miR-586	CLIP-seq
MIRT1274817	hsa-miR-589	CLIP-seq
MIRT1274818	hsa-miR-590-3p	CLIP-seq
MIRT2080840	hsa-miR-602	CLIP-seq
MIRT1274820	hsa-miR-603	CLIP-seq
MIRT1274821	hsa-miR-606	CLIP-seq
MIRT1274822	hsa-miR-613	CLIP-seq
MIRT1274823	hsa-miR-617	CLIP-seq
MIRT2306867	hsa-miR-623	CLIP-seq
MIRT2306868	hsa-miR-624	CLIP-seq
MIRT1274825	hsa-miR-631	CLIP-seq
MIRT1274827	hsa-miR-655	CLIP-seq
MIRT1274828	hsa-miR-656	CLIP-seq
MIRT2080842	hsa-miR-657	CLIP-seq
MIRT1274829	hsa-miR-659	CLIP-seq
MIRT1274830	hsa-miR-662	CLIP-seq
MIRT1274831	hsa-miR-663	CLIP-seq
MIRT1274833	hsa-miR-761	CLIP-seq
MIRT1274835	hsa-miR-765	CLIP-seq
MIRT2306869	hsa-miR-767-5p	CLIP-seq
MIRT1274836	hsa-miR-770-5p	CLIP-seq
MIRT2306870	hsa-miR-876-5p	CLIP-seq
MIRT2306871	hsa-miR-888	CLIP-seq
MIRT2080844	hsa-miR-890	CLIP-seq
MIRT1274837	hsa-miR-939	CLIP-seq
MIRT2080846	hsa-miR-940	CLIP-seq
MIRT1274838	hsa-miR-942	CLIP-seq
MIRT1274668	hsa-miR-203	CLIP-seq
MIRT1274672	hsa-miR-216a	CLIP-seq
MIRT1274673	hsa-miR-216b	CLIP-seq
MIRT1274696	hsa-miR-329	CLIP-seq
MIRT1274698	hsa-miR-338-5p	CLIP-seq
MIRT1274699	hsa-miR-342-3p	CLIP-seq
MIRT1274714	hsa-miR-374c	CLIP-seq
MIRT1274719	hsa-miR-3941	CLIP-seq
MIRT1274722	hsa-miR-4266	CLIP-seq
MIRT1274769	hsa-miR-4695-5p	CLIP-seq
MIRT1274774	hsa-miR-4712-5p	CLIP-seq
MIRT1274791	hsa-miR-4779	CLIP-seq
MIRT1274793	hsa-miR-4789-5p	CLIP-seq
MIRT2080833	hsa-miR-486-3p	CLIP-seq
MIRT1274798	hsa-miR-515-5p	CLIP-seq
MIRT1274811	hsa-miR-548h	CLIP-seq
MIRT1274812	hsa-miR-548j	CLIP-seq
MIRT1274820	hsa-miR-603	CLIP-seq
MIRT1274821	hsa-miR-606	CLIP-seq
MIRT1274827	hsa-miR-655	CLIP-seq
MIRT1274836	hsa-miR-770-5p	CLIP-seq
MIRT2080844	hsa-miR-890	CLIP-seq
MIRT2080802	hsa-miR-1268	CLIP-seq
MIRT2080803	hsa-miR-1268b	CLIP-seq
MIRT1274663	hsa-miR-146a	CLIP-seq
MIRT1274664	hsa-miR-146b-5p	CLIP-seq
MIRT1274675	hsa-miR-2467-3p	CLIP-seq
MIRT1274676	hsa-miR-28-3p	CLIP-seq
MIRT1274693	hsa-miR-3194-3p	CLIP-seq
MIRT2439707	hsa-miR-4304	CLIP-seq
MIRT1274733	hsa-miR-4417	CLIP-seq
MIRT1274737	hsa-miR-4436a	CLIP-seq
MIRT1274738	hsa-miR-4437	CLIP-seq
MIRT1274764	hsa-miR-4674	CLIP-seq
MIRT2080825	hsa-miR-4684-5p	CLIP-seq
MIRT1274774	hsa-miR-4712-5p	CLIP-seq
MIRT1274783	hsa-miR-4734	CLIP-seq
MIRT2080829	hsa-miR-4750	CLIP-seq
MIRT2439708	hsa-miR-4763-5p	CLIP-seq
MIRT1274790	hsa-miR-4767	CLIP-seq
MIRT1274817	hsa-miR-589	CLIP-seq
MIRT1274832	hsa-miR-760	CLIP-seq
MIRT1274835	hsa-miR-765	CLIP-seq
MIRT1274836	hsa-miR-770-5p	CLIP-seq
MIRT2439709	hsa-miR-938	CLIP-seq
MIRT2306836	hsa-miR-1286	CLIP-seq
MIRT2306842	hsa-miR-29a	CLIP-seq
MIRT2306843	hsa-miR-29b	CLIP-seq
MIRT2306844	hsa-miR-29c	CLIP-seq
MIRT2306852	hsa-miR-3663-3p	CLIP-seq
MIRT1274772	hsa-miR-4700-3p	CLIP-seq
MIRT2306859	hsa-miR-4722-5p	CLIP-seq
MIRT2306869	hsa-miR-767-5p	CLIP-seq
MIRT2604526	hsa-miR-1184	CLIP-seq
MIRT2604527	hsa-miR-1205	CLIP-seq
MIRT2604528	hsa-miR-1224-3p	CLIP-seq
MIRT2080799	hsa-miR-1228	CLIP-seq
MIRT1274651	hsa-miR-1236	CLIP-seq
MIRT2080800	hsa-miR-1260	CLIP-seq
MIRT2080801	hsa-miR-1260b	CLIP-seq
MIRT1274654	hsa-miR-1273g	CLIP-seq
MIRT2604529	hsa-miR-1280	CLIP-seq
MIRT1274659	hsa-miR-1321	CLIP-seq
MIRT1274662	hsa-miR-140-3p	CLIP-seq
MIRT1274663	hsa-miR-146a	CLIP-seq
MIRT1274664	hsa-miR-146b-5p	CLIP-seq
MIRT2080809	hsa-miR-188-3p	CLIP-seq
MIRT2604530	hsa-miR-1909	CLIP-seq
MIRT2080810	hsa-miR-193a-3p	CLIP-seq
MIRT2080811	hsa-miR-193b	CLIP-seq
MIRT1274671	hsa-miR-214	CLIP-seq
MIRT1274672	hsa-miR-216a	CLIP-seq
MIRT1274673	hsa-miR-216b	CLIP-seq
MIRT1274676	hsa-miR-28-3p	CLIP-seq
MIRT2604531	hsa-miR-31	CLIP-seq
MIRT2604532	hsa-miR-3128	CLIP-seq
MIRT2080813	hsa-miR-3156-3p	CLIP-seq
MIRT2306846	hsa-miR-3158-5p	CLIP-seq
MIRT1274689	hsa-miR-3180-5p	CLIP-seq
MIRT1274690	hsa-miR-3183	CLIP-seq
MIRT1274693	hsa-miR-3194-3p	CLIP-seq
MIRT1274697	hsa-miR-338-3p	CLIP-seq
MIRT1274699	hsa-miR-342-3p	CLIP-seq
MIRT1274704	hsa-miR-3614-3p	CLIP-seq
MIRT1274705	hsa-miR-3619-5p	CLIP-seq
MIRT2604533	hsa-miR-3647-3p	CLIP-seq
MIRT1274707	hsa-miR-3665	CLIP-seq
MIRT1274724	hsa-miR-4270	CLIP-seq
MIRT1274731	hsa-miR-4297	CLIP-seq
MIRT1274740	hsa-miR-4441	CLIP-seq
MIRT1274743	hsa-miR-4470	CLIP-seq
MIRT2080821	hsa-miR-4527	CLIP-seq
MIRT1274755	hsa-miR-4530	CLIP-seq
MIRT1274758	hsa-miR-4641	CLIP-seq
MIRT1274767	hsa-miR-4687-3p	CLIP-seq
MIRT1274768	hsa-miR-4690-5p	CLIP-seq
MIRT2604534	hsa-miR-4698	CLIP-seq
MIRT1274777	hsa-miR-4723-3p	CLIP-seq
MIRT1274784	hsa-miR-4739	CLIP-seq
MIRT1274789	hsa-miR-4756-5p	CLIP-seq
MIRT2080830	hsa-miR-4768-5p	CLIP-seq
MIRT1274796	hsa-miR-498	CLIP-seq
MIRT2604535	hsa-miR-548an	CLIP-seq
MIRT1274811	hsa-miR-548h	CLIP-seq
MIRT1274812	hsa-miR-548j	CLIP-seq
MIRT1274817	hsa-miR-589	CLIP-seq
MIRT1274819	hsa-miR-595	CLIP-seq
MIRT1274833	hsa-miR-761	CLIP-seq
MIRT1274834	hsa-miR-764	CLIP-seq
MIRT1274835	hsa-miR-765	CLIP-seq
MIRT2080843	hsa-miR-767-3p	CLIP-seq
MIRT2080845	hsa-miR-892b	CLIP-seq
MIRT1274644	hsa-miR-1	CLIP-seq
MIRT2604528	hsa-miR-1224-3p	CLIP-seq
MIRT2080799	hsa-miR-1228	CLIP-seq
MIRT1274651	hsa-miR-1236	CLIP-seq
MIRT2080800	hsa-miR-1260	CLIP-seq
MIRT2080801	hsa-miR-1260b	CLIP-seq
MIRT1274654	hsa-miR-1273g	CLIP-seq
MIRT2604529	hsa-miR-1280	CLIP-seq
MIRT1274662	hsa-miR-140-3p	CLIP-seq
MIRT2080809	hsa-miR-188-3p	CLIP-seq
MIRT2080810	hsa-miR-193a-3p	CLIP-seq
MIRT2080811	hsa-miR-193b	CLIP-seq
MIRT1274669	hsa-miR-206	CLIP-seq
MIRT1274671	hsa-miR-214	CLIP-seq
MIRT2604531	hsa-miR-31	CLIP-seq
MIRT2604532	hsa-miR-3128	CLIP-seq
MIRT2080813	hsa-miR-3156-3p	CLIP-seq
MIRT1274689	hsa-miR-3180-5p	CLIP-seq
MIRT1274690	hsa-miR-3183	CLIP-seq
MIRT1274697	hsa-miR-338-3p	CLIP-seq
MIRT1274705	hsa-miR-3619-5p	CLIP-seq
MIRT2604533	hsa-miR-3647-3p	CLIP-seq
MIRT2689060	hsa-miR-3659	CLIP-seq
MIRT1274707	hsa-miR-3665	CLIP-seq
MIRT1274710	hsa-miR-3673	CLIP-seq
MIRT1274718	hsa-miR-3929	CLIP-seq
MIRT2689061	hsa-miR-4300	CLIP-seq
MIRT1274734	hsa-miR-4419b	CLIP-seq
MIRT1274747	hsa-miR-4478	CLIP-seq
MIRT2080821	hsa-miR-4527	CLIP-seq
MIRT1274755	hsa-miR-4530	CLIP-seq
MIRT2689062	hsa-miR-4633-3p	CLIP-seq
MIRT1274767	hsa-miR-4687-3p	CLIP-seq
MIRT2604534	hsa-miR-4698	CLIP-seq
MIRT1274777	hsa-miR-4723-3p	CLIP-seq
MIRT2689063	hsa-miR-4730	CLIP-seq
MIRT1274782	hsa-miR-4733-5p	CLIP-seq
MIRT2080830	hsa-miR-4768-5p	CLIP-seq
MIRT2689064	hsa-miR-485-5p	CLIP-seq
MIRT1274796	hsa-miR-498	CLIP-seq
MIRT2604535	hsa-miR-548an	CLIP-seq
MIRT1274819	hsa-miR-595	CLIP-seq
MIRT1274822	hsa-miR-613	CLIP-seq
MIRT2689065	hsa-miR-658	CLIP-seq
MIRT1274833	hsa-miR-761	CLIP-seq
MIRT1274834	hsa-miR-764	CLIP-seq
MIRT2080843	hsa-miR-767-3p	CLIP-seq
MIRT2080844	hsa-miR-890	CLIP-seq
MIRT2080845	hsa-miR-892b	CLIP-seq
MIRT2689066	hsa-miR-920	CLIP-seq

Show/Hide all (1)

Transcription factor	Regulation	Reference
AR	Unknown	22282656

103

Show/Hide all (103)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003084	Process	Positive regulation of systemic arterial blood pressure	IEA
GO:0003723	Function	RNA binding	HDA	22658674
GO:0004721	Function	Phosphoprotein phosphatase activity	IEA
GO:0004725	Function	Protein tyrosine phosphatase activity	IDA	18074158, 21707536, 22169477
GO:0004725	Function	Protein tyrosine phosphatase activity	IEA
GO:0004725	Function	Protein tyrosine phosphatase activity	TAS
GO:0004726	Function	Non-membrane spanning protein tyrosine phosphatase activity	IBA
GO:0005158	Function	Insulin receptor binding	IEA
GO:0005515	Function	Protein binding	IPI	8702689, 8940134, 8999839, 9050838, 9355745, 9407132, 9418872, 9566916, 9600099, 10660596, 10889023, 11007774, 11106648, 11163213, 11506178, 11579209, 11694501, 11970898, 12023880, 12176037, 12237455, 12614164, 12634852, 12857726, 12907755, 14527337, 14722096, 15588987, 15821101, 158
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	ISS
GO:0005759	Component	Mitochondrial matrix	IEA
GO:0005769	Component	Early endosome	IBA
GO:0005769	Component	Early endosome	IDA	21135139
GO:0005769	Component	Early endosome	IEA
GO:0005769	Component	Early endosome	ISS
GO:0005783	Component	Endoplasmic reticulum	IBA
GO:0005783	Component	Endoplasmic reticulum	IDA
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	IDA	21135139
GO:0006470	Process	Protein dephosphorylation	IMP	22045810
GO:0008270	Function	Zinc ion binding	IDA	18074158
GO:0008285	Process	Negative regulation of cell population proliferation	IEA
GO:0008286	Process	Insulin receptor signaling pathway	IEA
GO:0009966	Process	Regulation of signal transduction	IMP	21135139
GO:0009968	Process	Negative regulation of signal transduction	TAS
GO:0010460	Process	Positive regulation of heart rate	IEA
GO:0010666	Process	Positive regulation of cardiac muscle cell apoptotic process	IEA
GO:0010812	Process	Negative regulation of cell-substrate adhesion	IEA
GO:0010977	Process	Negative regulation of neuron projection development	IEA
GO:0016020	Component	Membrane	IEA
GO:0016787	Function	Hydrolase activity	IEA
GO:0016791	Function	Phosphatase activity	IEA
GO:0019899	Function	Enzyme binding	IPI	22169477
GO:0019901	Function	Protein kinase binding	IBA
GO:0019901	Function	Protein kinase binding	IPI	22169477
GO:0030036	Process	Actin cytoskeleton organization	IMP	21135139
GO:0030061	Component	Mitochondrial crista	IEA
GO:0030100	Process	Regulation of endocytosis	IDA	21135139
GO:0030162	Process	Regulation of proteolysis	IEA
GO:0030948	Process	Negative regulation of vascular endothelial growth factor receptor signaling pathway	IEA
GO:0030948	Process	Negative regulation of vascular endothelial growth factor receptor signaling pathway	ISS
GO:0030968	Process	Endoplasmic reticulum unfolded protein response	IDA	22169477
GO:0030971	Function	Receptor tyrosine kinase binding	IEA
GO:0030971	Function	Receptor tyrosine kinase binding	IPI	18819921
GO:0031667	Process	Response to nutrient levels	IEA
GO:0031904	Component	Endosome lumen	IEA
GO:0032869	Process	Cellular response to insulin stimulus	IEA
GO:0032991	Component	Protein-containing complex	IDA	28246125
GO:0033157	Process	Regulation of intracellular protein transport	IMP	22045810
GO:0034620	Process	Cellular response to unfolded protein	TAS	22013210
GO:0034976	Process	Response to endoplasmic reticulum stress	IEA
GO:0035335	Process	Peptidyl-tyrosine dephosphorylation	IDA	21135139
GO:0035335	Process	Peptidyl-tyrosine dephosphorylation	IMP	14966296
GO:0035791	Process	Platelet-derived growth factor receptor-beta signaling pathway	IEA
GO:0035791	Process	Platelet-derived growth factor receptor-beta signaling pathway	IMP	14966296
GO:0036120	Process	Cellular response to platelet-derived growth factor stimulus	IEA
GO:0036498	Process	IRE1-mediated unfolded protein response	IEA
GO:0036498	Process	IRE1-mediated unfolded protein response	ISS
GO:0038020	Process	Insulin receptor recycling	IEA
GO:0043407	Process	Negative regulation of MAP kinase activity	IMP	22045810
GO:0044344	Process	Cellular response to fibroblast growth factor stimulus	IEA
GO:0045296	Function	Cadherin binding	HDA	25468996
GO:0046330	Process	Positive regulation of JNK cascade	IEA
GO:0046330	Process	Positive regulation of JNK cascade	ISS
GO:0046626	Process	Regulation of insulin receptor signaling pathway	IEA
GO:0046627	Process	Negative regulation of insulin receptor signaling pathway	NAS	11742412
GO:0046875	Function	Ephrin receptor binding	IPI	21135139
GO:0051721	Function	Protein phosphatase 2A binding	IEA
GO:0051898	Process	Negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	IEA
GO:0060338	Process	Regulation of type I interferon-mediated signaling pathway	IEA
GO:0060338	Process	Regulation of type I interferon-mediated signaling pathway	TAS
GO:0060397	Process	Growth hormone receptor signaling pathway via JAK-STAT	TAS
GO:0070373	Process	Negative regulation of ERK1 and ERK2 cascade	IBA
GO:0070373	Process	Negative regulation of ERK1 and ERK2 cascade	IEA
GO:0070373	Process	Negative regulation of ERK1 and ERK2 cascade	ISS
GO:0071456	Process	Cellular response to hypoxia	IEA
GO:0071732	Process	Cellular response to nitric oxide	IEA
GO:0097443	Component	Sorting endosome	IEA
GO:0097443	Component	Sorting endosome	ISS
GO:0097706	Process	Vascular endothelial cell response to oscillatory fluid shear stress	TAS
GO:0098554	Component	Cytoplasmic side of endoplasmic reticulum membrane	IDA	1739967
GO:0098794	Component	Postsynapse	IEA
GO:0098978	Component	Glutamatergic synapse	IEA
GO:0150052	Process	Regulation of postsynapse assembly	IEA
GO:1902202	Process	Regulation of hepatocyte growth factor receptor signaling pathway	IEA
GO:1902202	Process	Regulation of hepatocyte growth factor receptor signaling pathway	IMP	18819921
GO:1902236	Process	Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	IEA
GO:1902236	Process	Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	ISS
GO:1903896	Process	Positive regulation of IRE1-mediated unfolded protein response	TAS	22013210
GO:1903898	Process	Negative regulation of PERK-mediated unfolded protein response	IBA
GO:1903898	Process	Negative regulation of PERK-mediated unfolded protein response	IDA	21216966
GO:1903898	Process	Negative regulation of PERK-mediated unfolded protein response	IEA
GO:1904385	Process	Cellular response to angiotensin	IEA
GO:1904753	Process	Negative regulation of vascular associated smooth muscle cell migration	IEA
GO:1990090	Process	Cellular response to nerve growth factor stimulus	IEA
GO:1990776	Process	Response to angiotensin	IEA
GO:2000353	Process	Positive regulation of endothelial cell apoptotic process	IEA
GO:2000646	Process	Positive regulation of receptor catabolic process	IMP	22045810

MIM	HGNC	e!Ensembl
176885	9642	ENSG00000196396

P18031

Protein name

Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B)

Protein function

Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII-

PDB

1A5Y , 1AAX , 1BZC , 1BZH , 1BZJ , 1C83 , 1C84 , 1C85 , 1C86 , 1C87 , 1C88 , 1ECV , 1EEN , 1EEO , 1G1F , 1G1G , 1G1H , 1G7F , 1G7G , 1GFY , 1I57 , 1JF7 , 1KAK , 1KAV , 1L8G , 1LQF , 1NL9 , 1NNY , 1NO6 , 1NWE , 1NWL , 1NZ7 , 1OEM , 1OEO , 1OES , 1OET , 1OEU , 1OEV , 1ONY , 1ONZ , 1PA1 , 1PH0 , 1PTT , 1PTU , 1PTV , 1PTY , 1PXH , 1PYN , 1Q1M , 1Q6J , 1Q6M

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00102	Y_phosphatase	40 → 276	Protein-tyrosine phosphatase	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed in keratinocytes (at protein level). {ECO:0000269|PubMed:29043977}.

Sequence

MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLH
QEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLK
CAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWP
DFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKD
PSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDLE
PPPEHIPPPPRPPKRILEPHNGKCREFFPNHQWVKEETQEDKDCPIKEEKGSPLNAAPYG
IESMSQDTEVRSRVVGGSLRGAQAASPAKGEPSLPEKDEDHALSYWKPFLVNMCVATVLT
AGAYLCYRFLFNSNT

Sequence length

435

Interactions

View interactions

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Insulin resistance, susceptibility to	risk factor	rs16989673	RCV000014243
PTPN1-related disorder	Benign	rs35414863, rs74607837	RCV003915808 RCV003936142

Show/Hide Text Mining Associations (81)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Adenocarcinoma of Lung	Associate	32395869
Adenoma Chromophobe	Associate	36618415
Albuminuria	Associate	15189365
Anemia Aplastic	Associate	39179703
Behcet Syndrome	Associate	28166214, 29907633
Blood Coagulation Disorders	Associate	25042561
Breast Neoplasms	Associate	11007774, 18183590, 18332219, 19435911, 20952588, 23242616, 25590580, 27465552, 28378571, 28492548, 29183848, 36871762
Carcinogenesis	Associate	25590580, 38014992
Carcinoma Hepatocellular	Associate	26755347, 36618415
Carcinoma Hepatocellular	Stimulate	36741874
Carcinoma Renal Cell	Associate	21632985, 36618415
Colitis Ulcerative	Associate	35484353
Colorectal Neoplasms	Associate	26942883
Coronary Disease	Associate	15189365
Coronary Restenosis	Associate	35968900
Crohn Disease	Associate	28166214
Crohn Disease	Stimulate	28729389
Diabetes Complications	Associate	15189365
Diabetes Gestational	Associate	35449053
Diabetes Mellitus	Associate	11163213, 15189365, 15229188, 15715684, 21962515, 22688339, 28212750, 29348454, 30875760, 33400373, 36649358
Diabetes Mellitus Type 2	Associate	15189365, 15715684, 15866871, 15919835, 16407290, 16677372, 17674807, 24865376, 30729132
Diabetes Mellitus Type 2	Stimulate	22474028
Diabetic Foot	Associate	22688339
Dyslipidemias	Associate	16677372
Essential Hypertension	Associate	15229188
Gastrointestinal Stromal Tumors	Associate	30804049
Glioblastoma	Associate	38014992
Glioma	Associate	16319070
Glioma of Brain Familial	Associate	36618415
HAIR AN syndrome	Associate	36649358
Hereditary Breast and Ovarian Cancer Syndrome	Associate	31774495
Hodgkin Disease	Associate	21144060, 28082443, 29650799, 32079702, 33382412, 36723991
Hypertension	Associate	15189365, 15229188
Inflammation	Associate	28958600
Insulin Resistance	Associate	11136729, 11833006, 15229188, 17908551, 26193288, 26402673, 35449053, 36649358
Insulin Resistance	Stimulate	27516476
Intracranial Aneurysm	Associate	36451838
Kidney Diseases	Associate	36618415
Lead Poisoning Nervous System	Associate	26193288
Leprosy	Associate	28166214
Leukemia B Cell	Associate	15591113
Leukemia Lymphocytic Chronic B Cell	Associate	23348582
Leukemia Myelogenous Chronic BCR ABL Positive	Associate	19091943, 21795709, 36086954
Leukemia Myeloid Acute	Associate	36618415
Liver Failure	Inhibit	23867504
Lymphatic Metastasis	Associate	27465552, 33469269
Lymphatic Metastasis	Stimulate	28378571
Lymphoma	Associate	35806064
Lymphoma B Cell	Associate	26599546, 35806064
Malformations of Cortical Development Group I	Associate	24809452
Mercury Poisoning Nervous System	Associate	28958600
Metabolic Syndrome	Associate	15229188, 15866871
Mitochondrial Diseases	Associate	36649358
Myopathies Structural Congenital	Associate	27268263
Neoplasm Metastasis	Associate	26942883, 30804049, 31837707, 35661947
Neoplasm Metastasis	Inhibit	32395869
Neoplasms	Associate	19091943, 20504764, 23242616, 28212750, 28378571, 31774495, 33093643, 33469269, 35806064, 36012311, 36618415, 36973833, 38014992, 7949181
Neoplasms	Inhibit	24809452, 28492548
Neoplasms	Stimulate	36741874
Neoplasms Adipose Tissue	Associate	15919835, 36369476
Neuroblastoma	Associate	31837707
Neurologic Manifestations	Stimulate	28729389
Non alcoholic Fatty Liver Disease	Associate	36649358
Obesity	Associate	11163213, 15229188, 15866871, 16407290, 16677372, 17674807, 18846048, 21962515, 24865376, 28492548, 29348454, 30729132, 33400373, 33782530, 36369476, 9218523 View all (1 more)
Osteosarcoma	Associate	32851074
Ovarian Neoplasms	Associate	23814047, 29920310, 39179931
Precursor Cell Lymphoblastic Leukemia Lymphoma	Associate	28245838
Pulmonary Disease Chronic Obstructive	Associate	38162988
Recombinant chromosome 8 syndrome	Associate	36618415
Renal Insufficiency	Associate	36649358
Respiratory Sounds	Associate	37053215
Squamous Cell Carcinoma of Head and Neck	Associate	19430297
Stomach Diseases	Associate	25590580
Stomach Neoplasms	Associate	25590580, 35661947
Trigeminal Neuralgia	Associate	38158702
Triple Negative Breast Neoplasms	Associate	39819723
Turner Syndrome	Associate	23761422, 27651465
Urinary Bladder Neoplasms	Associate	24459064
Uterine Cervical Neoplasms	Associate	33469269
Uveal melanoma	Associate	36618415
Weight Loss	Associate	33400373

PTPN1 (protein tyrosine phosphatase non-receptor type 1)