Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
9491
Gene name Gene Name - the full gene name approved by the HGNC.
Proteasome inhibitor subunit 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
PSMF1
Synonyms (NCBI Gene) Gene synonyms aliases
PI31
Chromosome Chromosome number
20
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
20p13
Summary Summary of gene provided in NCBI Entrez Gene.
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits a
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT049749 hsa-miR-92a-3p CLASH 23622248
MIRT044684 hsa-miR-320a CLASH 23622248
MIRT043618 hsa-miR-151a-3p CLASH 23622248
MIRT039672 hsa-miR-615-3p CLASH 23622248
MIRT718204 hsa-miR-451b HITS-CLIP 19536157
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000165 Process MAPK cascade TAS
GO:0000209 Process Protein polyubiquitination TAS
GO:0002223 Process Stimulatory C-type lectin receptor signaling pathway TAS
GO:0002479 Process Antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent TAS
GO:0004866 Function Endopeptidase inhibitor activity NAS 10764772
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
617858 9571 ENSG00000125818
Protein
UniProt ID Q92530
Protein name Proteasome inhibitor PI31 subunit (hPI31)
Protein function Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28. {ECO
PDB 2VT8 , 4OUH
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF11566 PI31_Prot_N 11 149 PI31 proteasome regulator N-terminal Family
PF08577 PI31_Prot_C 153 248 PI31 proteasome regulator Family
Sequence
Sequence length 271
Interactions View interactions