PSMF1 (proteasome inhibitor subunit 1)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 9491 |
| Gene name | Proteasome inhibitor subunit 1 |
| Gene symbol | PSMF1 |
| Synonyms (NCBI Gene) |
PI31
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| Chromosome | 20 |
| Chromosome location | 20p13 |
| Summary | The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits a |
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miRNA
miRNA information provided by mirtarbase database.
469
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
20
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q92530 | |||||||||||||||
| Protein name | Proteasome inhibitor PI31 subunit (hPI31) | |||||||||||||||
| Protein function | Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28. {ECO | |||||||||||||||
| PDB | 2VT8 , 4OUH | |||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 271 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
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