Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs Transcription factors Other IDs Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	5717
Gene name Gene Name - the full gene name approved by the HGNC.	Proteasome 26S subunit, non-ATPase 11
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	PSMD11
Synonyms (NCBI Gene) Gene synonyms aliases	Rpn6, S9, p44.5
Chromosome Chromosome number	17
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	17q11.2
Summary Summary of gene provided in NCBI Entrez Gene.	The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits a

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miRTarBase ID	miRNA	Experiments	Reference
MIRT027649	hsa-miR-98-5p	Microarray	19088304
MIRT031677	hsa-miR-16-5p	Proteomics	18668040
MIRT048989	hsa-miR-92a-3p	CLASH	23622248
MIRT048802	hsa-miR-93-5p	CLASH	23622248
MIRT047502	hsa-miR-10b-5p	CLASH	23622248
MIRT044706	hsa-miR-320a	CLASH	23622248
MIRT043061	hsa-miR-324-5p	CLASH	23622248
MIRT037727	hsa-miR-744-5p	CLASH	23622248
MIRT037338	hsa-miR-877-5p	CLASH	23622248
MIRT037010	hsa-miR-877-3p	CLASH	23622248
MIRT036621	hsa-miR-940	CLASH	23622248
MIRT036255	hsa-miR-1236-3p	CLASH	23622248
MIRT616002	hsa-miR-449b-3p	HITS-CLIP	23824327
MIRT616001	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT616000	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT609054	hsa-miR-744-3p	HITS-CLIP	24906430
MIRT470182	hsa-miR-6873-5p	PAR-CLIP	24398324
MIRT470181	hsa-miR-6888-5p	PAR-CLIP	24398324
MIRT470180	hsa-miR-4433b-3p	PAR-CLIP	24398324
MIRT470179	hsa-miR-6760-5p	PAR-CLIP	24398324
MIRT470178	hsa-miR-4419a	PAR-CLIP	24398324
MIRT470177	hsa-miR-4510	PAR-CLIP	24398324
MIRT470176	hsa-miR-6127	PAR-CLIP	24398324
MIRT470175	hsa-miR-6129	PAR-CLIP	24398324
MIRT470174	hsa-miR-6130	PAR-CLIP	24398324
MIRT470173	hsa-miR-6133	PAR-CLIP	24398324
MIRT470172	hsa-miR-4481	PAR-CLIP	24398324
MIRT470171	hsa-miR-4745-5p	PAR-CLIP	24398324
MIRT470170	hsa-miR-765	PAR-CLIP	24398324
MIRT470168	hsa-miR-6878-5p	PAR-CLIP	24398324
MIRT470169	hsa-miR-6731-5p	PAR-CLIP	24398324
MIRT470167	hsa-miR-8085	PAR-CLIP	24398324
MIRT470166	hsa-miR-1233-5p	PAR-CLIP	24398324
MIRT470165	hsa-miR-6778-5p	PAR-CLIP	24398324
MIRT470164	hsa-miR-30c-1-3p	PAR-CLIP	24398324
MIRT470163	hsa-miR-30c-2-3p	PAR-CLIP	24398324
MIRT470162	hsa-miR-6788-5p	PAR-CLIP	24398324
MIRT492540	hsa-miR-4476	PAR-CLIP	23592263
MIRT492539	hsa-miR-6876-5p	PAR-CLIP	23592263
MIRT492538	hsa-miR-6801-3p	PAR-CLIP	23592263
MIRT492537	hsa-miR-6810-3p	PAR-CLIP	23592263
MIRT492536	hsa-miR-331-3p	PAR-CLIP	23592263
MIRT492534	hsa-miR-4308	PAR-CLIP	23592263
MIRT492535	hsa-miR-4254	PAR-CLIP	23592263
MIRT492533	hsa-miR-605-3p	PAR-CLIP	23592263
MIRT492532	hsa-miR-766-5p	PAR-CLIP	23592263
MIRT470169	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT470167	hsa-miR-8085	PAR-CLIP	23592263
MIRT492531	hsa-miR-4728-5p	PAR-CLIP	23592263
MIRT492530	hsa-miR-6515-5p	PAR-CLIP	23592263
MIRT470196	hsa-miR-141-3p	PAR-CLIP	23592263
MIRT470195	hsa-miR-200a-3p	PAR-CLIP	23592263
MIRT470193	hsa-miR-4688	PAR-CLIP	23592263
MIRT470194	hsa-miR-6743-5p	PAR-CLIP	23592263
MIRT470192	hsa-miR-4768-3p	PAR-CLIP	23592263
MIRT470191	hsa-miR-1253	PAR-CLIP	23592263
MIRT470190	hsa-miR-3184-5p	PAR-CLIP	23592263
MIRT470189	hsa-miR-423-5p	PAR-CLIP	23592263
MIRT470188	hsa-miR-873-5p	PAR-CLIP	23592263
MIRT470187	hsa-miR-1286	PAR-CLIP	23592263
MIRT470186	hsa-miR-4722-5p	PAR-CLIP	23592263
MIRT470185	hsa-miR-4434	PAR-CLIP	23592263
MIRT470184	hsa-miR-4516	PAR-CLIP	23592263
MIRT470183	hsa-miR-5703	PAR-CLIP	23592263
MIRT470182	hsa-miR-6873-5p	PAR-CLIP	23592263
MIRT470181	hsa-miR-6888-5p	PAR-CLIP	23592263
MIRT470180	hsa-miR-4433b-3p	PAR-CLIP	23592263
MIRT470179	hsa-miR-6760-5p	PAR-CLIP	23592263
MIRT470178	hsa-miR-4419a	PAR-CLIP	23592263
MIRT470177	hsa-miR-4510	PAR-CLIP	23592263
MIRT470176	hsa-miR-6127	PAR-CLIP	23592263
MIRT470175	hsa-miR-6129	PAR-CLIP	23592263
MIRT470174	hsa-miR-6130	PAR-CLIP	23592263
MIRT470173	hsa-miR-6133	PAR-CLIP	23592263
MIRT470172	hsa-miR-4481	PAR-CLIP	23592263
MIRT470171	hsa-miR-4745-5p	PAR-CLIP	23592263
MIRT470170	hsa-miR-765	PAR-CLIP	23592263
MIRT470168	hsa-miR-6878-5p	PAR-CLIP	23592263
MIRT470169	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT470167	hsa-miR-8085	PAR-CLIP	23592263
MIRT470166	hsa-miR-1233-5p	PAR-CLIP	23592263
MIRT470165	hsa-miR-6778-5p	PAR-CLIP	23592263
MIRT470164	hsa-miR-30c-1-3p	PAR-CLIP	23592263
MIRT470163	hsa-miR-30c-2-3p	PAR-CLIP	23592263
MIRT470162	hsa-miR-6788-5p	PAR-CLIP	23592263
MIRT439883	hsa-miR-142-3p	HITS-CLIP	22473208
MIRT439883	hsa-miR-142-3p	HITS-CLIP	22473208
MIRT616002	hsa-miR-449b-3p	HITS-CLIP	23824327
MIRT616001	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT616000	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT470182	hsa-miR-6873-5p	PAR-CLIP	24398324
MIRT470181	hsa-miR-6888-5p	PAR-CLIP	24398324
MIRT470180	hsa-miR-4433b-3p	PAR-CLIP	24398324
MIRT470179	hsa-miR-6760-5p	PAR-CLIP	24398324
MIRT470178	hsa-miR-4419a	PAR-CLIP	24398324
MIRT470177	hsa-miR-4510	PAR-CLIP	24398324
MIRT470176	hsa-miR-6127	PAR-CLIP	24398324
MIRT470175	hsa-miR-6129	PAR-CLIP	24398324
MIRT470174	hsa-miR-6130	PAR-CLIP	24398324
MIRT470173	hsa-miR-6133	PAR-CLIP	24398324
MIRT470172	hsa-miR-4481	PAR-CLIP	24398324
MIRT470171	hsa-miR-4745-5p	PAR-CLIP	24398324
MIRT470170	hsa-miR-765	PAR-CLIP	24398324
MIRT470168	hsa-miR-6878-5p	PAR-CLIP	24398324
MIRT470169	hsa-miR-6731-5p	PAR-CLIP	24398324
MIRT470167	hsa-miR-8085	PAR-CLIP	24398324
MIRT470166	hsa-miR-1233-5p	PAR-CLIP	24398324
MIRT470165	hsa-miR-6778-5p	PAR-CLIP	24398324
MIRT470164	hsa-miR-30c-1-3p	PAR-CLIP	24398324
MIRT470163	hsa-miR-30c-2-3p	PAR-CLIP	24398324
MIRT470162	hsa-miR-6788-5p	PAR-CLIP	24398324
MIRT492540	hsa-miR-4476	PAR-CLIP	23592263
MIRT492539	hsa-miR-6876-5p	PAR-CLIP	23592263
MIRT492538	hsa-miR-6801-3p	PAR-CLIP	23592263
MIRT492537	hsa-miR-6810-3p	PAR-CLIP	23592263
MIRT492536	hsa-miR-331-3p	PAR-CLIP	23592263
MIRT492534	hsa-miR-4308	PAR-CLIP	23592263
MIRT492535	hsa-miR-4254	PAR-CLIP	23592263
MIRT492533	hsa-miR-605-3p	PAR-CLIP	23592263
MIRT492532	hsa-miR-766-5p	PAR-CLIP	23592263
MIRT470169	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT470167	hsa-miR-8085	PAR-CLIP	23592263
MIRT492531	hsa-miR-4728-5p	PAR-CLIP	23592263
MIRT492530	hsa-miR-6515-5p	PAR-CLIP	23592263
MIRT470196	hsa-miR-141-3p	PAR-CLIP	23592263
MIRT470195	hsa-miR-200a-3p	PAR-CLIP	23592263
MIRT470193	hsa-miR-4688	PAR-CLIP	23592263
MIRT470194	hsa-miR-6743-5p	PAR-CLIP	23592263
MIRT470192	hsa-miR-4768-3p	PAR-CLIP	23592263
MIRT470191	hsa-miR-1253	PAR-CLIP	23592263
MIRT470190	hsa-miR-3184-5p	PAR-CLIP	23592263
MIRT470189	hsa-miR-423-5p	PAR-CLIP	23592263
MIRT470188	hsa-miR-873-5p	PAR-CLIP	23592263
MIRT470187	hsa-miR-1286	PAR-CLIP	23592263
MIRT470186	hsa-miR-4722-5p	PAR-CLIP	23592263
MIRT470185	hsa-miR-4434	PAR-CLIP	23592263
MIRT470184	hsa-miR-4516	PAR-CLIP	23592263
MIRT470183	hsa-miR-5703	PAR-CLIP	23592263
MIRT470182	hsa-miR-6873-5p	PAR-CLIP	23592263
MIRT470181	hsa-miR-6888-5p	PAR-CLIP	23592263
MIRT470180	hsa-miR-4433b-3p	PAR-CLIP	23592263
MIRT470179	hsa-miR-6760-5p	PAR-CLIP	23592263
MIRT470178	hsa-miR-4419a	PAR-CLIP	23592263
MIRT470177	hsa-miR-4510	PAR-CLIP	23592263
MIRT470176	hsa-miR-6127	PAR-CLIP	23592263
MIRT470175	hsa-miR-6129	PAR-CLIP	23592263
MIRT470174	hsa-miR-6130	PAR-CLIP	23592263
MIRT470173	hsa-miR-6133	PAR-CLIP	23592263
MIRT470172	hsa-miR-4481	PAR-CLIP	23592263
MIRT470171	hsa-miR-4745-5p	PAR-CLIP	23592263
MIRT470170	hsa-miR-765	PAR-CLIP	23592263
MIRT470168	hsa-miR-6878-5p	PAR-CLIP	23592263
MIRT470169	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT470167	hsa-miR-8085	PAR-CLIP	23592263
MIRT470166	hsa-miR-1233-5p	PAR-CLIP	23592263
MIRT470165	hsa-miR-6778-5p	PAR-CLIP	23592263
MIRT470164	hsa-miR-30c-1-3p	PAR-CLIP	23592263
MIRT470163	hsa-miR-30c-2-3p	PAR-CLIP	23592263
MIRT470162	hsa-miR-6788-5p	PAR-CLIP	23592263
MIRT1270435	hsa-miR-4639-3p	CLIP-seq
MIRT1270436	hsa-miR-515-5p	CLIP-seq
MIRT1270437	hsa-miR-548v	CLIP-seq
MIRT1270438	hsa-miR-603	CLIP-seq
MIRT2079461	hsa-miR-1185	CLIP-seq
MIRT2079462	hsa-miR-1228	CLIP-seq
MIRT2079463	hsa-miR-150	CLIP-seq
MIRT2079464	hsa-miR-3147	CLIP-seq
MIRT2079465	hsa-miR-3605-5p	CLIP-seq
MIRT2079466	hsa-miR-361-3p	CLIP-seq
MIRT2079467	hsa-miR-3652	CLIP-seq
MIRT2079468	hsa-miR-3679-3p	CLIP-seq
MIRT2079469	hsa-miR-3679-5p	CLIP-seq
MIRT2079470	hsa-miR-4258	CLIP-seq
MIRT2079471	hsa-miR-4259	CLIP-seq
MIRT2079472	hsa-miR-4286	CLIP-seq
MIRT2079473	hsa-miR-4430	CLIP-seq
MIRT2079474	hsa-miR-4446-5p	CLIP-seq
MIRT2079475	hsa-miR-4505	CLIP-seq
MIRT1270435	hsa-miR-4639-3p	CLIP-seq
MIRT2079476	hsa-miR-4640-5p	CLIP-seq
MIRT2079477	hsa-miR-4726-5p	CLIP-seq
MIRT2079478	hsa-miR-501-3p	CLIP-seq
MIRT2079479	hsa-miR-502-3p	CLIP-seq
MIRT1270436	hsa-miR-515-5p	CLIP-seq
MIRT1270437	hsa-miR-548v	CLIP-seq
MIRT1270438	hsa-miR-603	CLIP-seq
MIRT2079480	hsa-miR-647	CLIP-seq
MIRT2079481	hsa-miR-767-5p	CLIP-seq
MIRT2079462	hsa-miR-1228	CLIP-seq
MIRT2079467	hsa-miR-3652	CLIP-seq
MIRT2079470	hsa-miR-4258	CLIP-seq
MIRT2079473	hsa-miR-4430	CLIP-seq
MIRT2079475	hsa-miR-4505	CLIP-seq
MIRT1270435	hsa-miR-4639-3p	CLIP-seq
MIRT2079478	hsa-miR-501-3p	CLIP-seq
MIRT2079479	hsa-miR-502-3p	CLIP-seq
MIRT1270436	hsa-miR-515-5p	CLIP-seq
MIRT1270437	hsa-miR-548v	CLIP-seq
MIRT1270438	hsa-miR-603	CLIP-seq
MIRT2079480	hsa-miR-647	CLIP-seq
MIRT2079481	hsa-miR-767-5p	CLIP-seq
MIRT2079462	hsa-miR-1228	CLIP-seq
MIRT2079467	hsa-miR-3652	CLIP-seq
MIRT2079470	hsa-miR-4258	CLIP-seq
MIRT2079473	hsa-miR-4430	CLIP-seq
MIRT2079475	hsa-miR-4505	CLIP-seq
MIRT1270435	hsa-miR-4639-3p	CLIP-seq
MIRT2079478	hsa-miR-501-3p	CLIP-seq
MIRT2079479	hsa-miR-502-3p	CLIP-seq
MIRT1270436	hsa-miR-515-5p	CLIP-seq
MIRT1270438	hsa-miR-603	CLIP-seq
MIRT2079480	hsa-miR-647	CLIP-seq
MIRT2079481	hsa-miR-767-5p	CLIP-seq
MIRT2603035	hsa-miR-1179	CLIP-seq
MIRT2079461	hsa-miR-1185	CLIP-seq
MIRT2079462	hsa-miR-1228	CLIP-seq
MIRT2603036	hsa-miR-186	CLIP-seq
MIRT2079465	hsa-miR-3605-5p	CLIP-seq
MIRT2079466	hsa-miR-361-3p	CLIP-seq
MIRT2079467	hsa-miR-3652	CLIP-seq
MIRT2079468	hsa-miR-3679-3p	CLIP-seq
MIRT2079469	hsa-miR-3679-5p	CLIP-seq
MIRT2079470	hsa-miR-4258	CLIP-seq
MIRT2079473	hsa-miR-4430	CLIP-seq
MIRT2079474	hsa-miR-4446-5p	CLIP-seq
MIRT2079475	hsa-miR-4505	CLIP-seq
MIRT1270435	hsa-miR-4639-3p	CLIP-seq
MIRT2603037	hsa-miR-4773	CLIP-seq
MIRT2079478	hsa-miR-501-3p	CLIP-seq
MIRT2079479	hsa-miR-502-3p	CLIP-seq
MIRT1270436	hsa-miR-515-5p	CLIP-seq
MIRT2603038	hsa-miR-548ac	CLIP-seq
MIRT2603039	hsa-miR-548ae	CLIP-seq
MIRT2603040	hsa-miR-548aj	CLIP-seq
MIRT2603041	hsa-miR-548am	CLIP-seq
MIRT2603042	hsa-miR-548d-3p	CLIP-seq
MIRT2603043	hsa-miR-548n	CLIP-seq
MIRT2603044	hsa-miR-548x	CLIP-seq
MIRT2603045	hsa-miR-548z	CLIP-seq
MIRT1270438	hsa-miR-603	CLIP-seq
MIRT2603046	hsa-miR-615-3p	CLIP-seq
MIRT2079480	hsa-miR-647	CLIP-seq
MIRT2079481	hsa-miR-767-5p	CLIP-seq
MIRT2603035	hsa-miR-1179	CLIP-seq
MIRT2079461	hsa-miR-1185	CLIP-seq
MIRT2079462	hsa-miR-1228	CLIP-seq
MIRT2603036	hsa-miR-186	CLIP-seq
MIRT2079465	hsa-miR-3605-5p	CLIP-seq
MIRT2079466	hsa-miR-361-3p	CLIP-seq
MIRT2079467	hsa-miR-3652	CLIP-seq
MIRT2079468	hsa-miR-3679-3p	CLIP-seq
MIRT2079469	hsa-miR-3679-5p	CLIP-seq
MIRT2079470	hsa-miR-4258	CLIP-seq
MIRT2079473	hsa-miR-4430	CLIP-seq
MIRT2079474	hsa-miR-4446-5p	CLIP-seq
MIRT2079475	hsa-miR-4505	CLIP-seq
MIRT1270435	hsa-miR-4639-3p	CLIP-seq
MIRT2603037	hsa-miR-4773	CLIP-seq
MIRT2079478	hsa-miR-501-3p	CLIP-seq
MIRT2079479	hsa-miR-502-3p	CLIP-seq
MIRT1270436	hsa-miR-515-5p	CLIP-seq
MIRT2603038	hsa-miR-548ac	CLIP-seq
MIRT2603039	hsa-miR-548ae	CLIP-seq
MIRT2603040	hsa-miR-548aj	CLIP-seq
MIRT2603041	hsa-miR-548am	CLIP-seq
MIRT2603042	hsa-miR-548d-3p	CLIP-seq
MIRT2603043	hsa-miR-548n	CLIP-seq
MIRT2603044	hsa-miR-548x	CLIP-seq
MIRT2603045	hsa-miR-548z	CLIP-seq
MIRT1270438	hsa-miR-603	CLIP-seq
MIRT2603046	hsa-miR-615-3p	CLIP-seq
MIRT2079480	hsa-miR-647	CLIP-seq
MIRT2079481	hsa-miR-767-5p	CLIP-seq

Transcription factors

Show/Hide all(1)

Transcription factor	Regulation	Reference
FOXO4	Unknown	22972301

Show/Hide all(42)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000165	Process	MAPK cascade	TAS
GO:0000209	Process	Protein polyubiquitination	TAS
GO:0000502	Component	Proteasome complex	IDA	17323924
GO:0002223	Process	Stimulatory C-type lectin receptor signaling pathway	TAS
GO:0002479	Process	Antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	TAS
GO:0005198	Function	Structural molecule activity	IBA	21873635
GO:0005515	Function	Protein binding	IPI	23455924, 32296183
GO:0005576	Component	Extracellular region	TAS
GO:0005634	Component	Nucleus	HDA	21630459
GO:0005654	Component	Nucleoplasm	TAS
GO:0005829	Component	Cytosol	TAS
GO:0006511	Process	Ubiquitin-dependent protein catabolic process	IBA	21873635
GO:0006511	Process	Ubiquitin-dependent protein catabolic process	IMP	22972301
GO:0006521	Process	Regulation of cellular amino acid metabolic process	TAS
GO:0008541	Component	Proteasome regulatory particle, lid subcomplex	IBA	21873635
GO:0010972	Process	Negative regulation of G2/M transition of mitotic cell cycle	TAS
GO:0016020	Component	Membrane	HDA	19946888
GO:0016579	Process	Protein deubiquitination	TAS
GO:0022624	Component	Proteasome accessory complex	IDA	22972301
GO:0031145	Process	Anaphase-promoting complex-dependent catabolic process	TAS
GO:0031146	Process	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	TAS
GO:0033209	Process	Tumor necrosis factor-mediated signaling pathway	TAS
GO:0034774	Component	Secretory granule lumen	TAS
GO:0038061	Process	NIK/NF-kappaB signaling	TAS
GO:0038095	Process	Fc-epsilon receptor signaling pathway	TAS
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	TAS
GO:0043248	Process	Proteasome assembly	IBA	21873635
GO:0043248	Process	Proteasome assembly	IMP	22972301
GO:0043312	Process	Neutrophil degranulation	TAS
GO:0043488	Process	Regulation of mRNA stability	TAS
GO:0043687	Process	Post-translational protein modification	TAS
GO:0048863	Process	Stem cell differentiation	IMP	22972301
GO:0050852	Process	T cell receptor signaling pathway	TAS
GO:0055085	Process	Transmembrane transport	TAS
GO:0060071	Process	Wnt signaling pathway, planar cell polarity pathway	TAS
GO:0061418	Process	Regulation of transcription from RNA polymerase II promoter in response to hypoxia	TAS
GO:0070498	Process	Interleukin-1-mediated signaling pathway	TAS
GO:0090090	Process	Negative regulation of canonical Wnt signaling pathway	TAS
GO:0090263	Process	Positive regulation of canonical Wnt signaling pathway	TAS
GO:1901990	Process	Regulation of mitotic cell cycle phase transition	TAS
GO:1902036	Process	Regulation of hematopoietic stem cell differentiation	TAS
GO:1904813	Component	Ficolin-1-rich granule lumen	TAS

MIM	HGNC	e!Ensembl
604449	9556	ENSG00000108671

Protein

UniProt ID

O00231

Protein name

26S proteasome non-ATPase regulatory subunit 11 (26S proteasome regulatory subunit RPN6) (26S proteasome regulatory subunit S9) (26S proteasome regulatory subunit p44.5)

Protein function

Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which

PDB

5GJQ , 5GJR , 5L4K , 5LN3 , 5M32 , 5T0C , 5T0G , 5T0H , 5T0I , 5T0J , 5VFP , 5VFQ , 5VFR , 5VFS , 5VFT , 5VFU , 5VGZ , 5VHF , 5VHH , 5VHI , 5VHS , 6MSB , 6MSD , 6MSE , 6MSG , 6MSH , 6MSJ , 6MSK , 6WJD , 6WJN , 7QXN , 7QXP , 7QXU , 7QXW , 7QXX , 7QY7 , 7QYA , 7QYB , 7W37 , 7W38 , 7W39 , 7W3A , 7W3B , 7W3C , 7W3F , 7W3G , 7W3H , 7W3I , 7W3J , 7W3K , 7W3M

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF18055	RPN6_N	12 → 129	26S proteasome regulatory subunit RPN6 N-terminal domain	Domain
PF01399	PCI	285 → 389	PCI domain	Domain
PF18503	RPN6_C_helix	393 → 419	26S proteasome subunit RPN6 C-terminal helix domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Highly expressed in embryonic stem cells (ESCs). Expression decreases as ESCs differentiate. {ECO:0000269|PubMed:22972301}.

Sequence

MAAAAVVEFQRAQSLLSTDREASIDILHSIVKRDIQENDEEAVQVKEQSILELGSLLAKT
GQAAELGGLLKYVRPFLNSISKAKAARLVRSLLDLFLDMEAATGQEVELCLECIEWAKSE
KRTFLRQALEARLVSLYFDTKRYQEALHLGSQLLRELKKMDDKALLVEVQLLESKTYHAL
SNLPKARAALTSARTTANAIYCPPKLQATLDMQSGIIHAAEEKDWKTAYSYFYEAFEGYD
SIDSPKAITSLKYMLLCKIMLNTPEDVQALVSGKLALRYAGRQTEALKCVAQASKNRSLA
DFEKALTDYRAELRDDPIISTHLAKLYDNLLEQNLIRVIEPFSRVQIEHISSLIKLSKAD
VERKLSQMILDKKFHGILDQGEGVLIIFDEPPVDKTYEAALETIQNMSKVVDSLYNKAKK
LT

Sequence length

422

Interactions

View interactions

Show/Hide Unknown Diseases (2)

Disease term	Disease name	Source
Unknown
Neurodevelopmental Disorders	complex neurodevelopmental disorder	GenCC
Schizophrenia	Schizophrenia	GWAS

Show/Hide Text Mining Associations (8)

Disease Name	Relationship Type	References
Associations from Text Mining
Amyotrophic Lateral Sclerosis	Associate	40033250
Breast Neoplasms	Associate	30670769
Carcinoma Pancreatic Ductal	Associate	33525943, 35459186
Lymphatic Metastasis	Associate	30670769
Neoplasm Metastasis	Associate	31173190
Neoplasms	Associate	36123629
Pancreatic Neoplasms	Associate	24105791
Spinal Cord Injuries	Associate	17218363

PSMD11 (proteasome 26S subunit, non-ATPase 11)