Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs Transcription factors Other IDs Associated diseases
Entrez ID	5581
Gene name	Protein kinase C epsilon
Gene symbol	PRKCE
Synonyms (NCBI Gene)	PKCEnPKC-epsilon
Chromosome	2
Chromosome location	2p21
Summary	Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved

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miRTarBase ID	miRNA	Experiments	Reference
MIRT003667	hsa-miR-205-5p	immunoblotqRT-PCR	19244118
MIRT007205	hsa-miR-1-3p	Luciferase reporter assay	23226300
MIRT007286	hsa-miR-31-5p	Luciferase reporter assay	23364795
MIRT027937	hsa-miR-96-5p	Sequencing	20371350
MIRT030913	hsa-miR-21-5p	Microarray	18591254
MIRT043664	hsa-miR-342-3p	CLASH	23622248
MIRT052955	hsa-miR-107	5.0	22158047
MIRT052955	hsa-miR-107	5.0	22158047
MIRT052955	hsa-miR-107	5.0	22158047
MIRT052955	hsa-miR-107	5.0	22158047
MIRT052955	hsa-miR-107	Luciferase reporter assayqRT-PCRWestern blot	22158047
MIRT438113	hsa-miR-146a-5p	Luciferase reporter assay	23457043
MIRT438113	hsa-miR-146a-5p	Luciferase reporter assay	23457043
MIRT438113	hsa-miR-146a-5p	Luciferase reporter assay	23457043
MIRT438113	hsa-miR-146a-5p	Luciferase reporter assay	23457043
MIRT438113	hsa-miR-146a-5p	qRT-PCRLuciferase reporter assayWestern blot	25308712
MIRT438113	hsa-miR-146a-5p	qRT-PCRLuciferase reporter assayWestern blot	25308712
MIRT438113	hsa-miR-146a-5p	qRT-PCRLuciferase reporter assayWestern blot	25308712
MIRT438113	hsa-miR-146a-5p	qRT-PCRLuciferase reporter assayWestern blot	25308712
MIRT1263108	hsa-miR-101	CLIP-seq
MIRT1263109	hsa-miR-103a	CLIP-seq
MIRT1263110	hsa-miR-105	CLIP-seq
MIRT1263111	hsa-miR-1207-3p	CLIP-seq
MIRT1263112	hsa-miR-1208	CLIP-seq
MIRT1263113	hsa-miR-1227	CLIP-seq
MIRT1263114	hsa-miR-1271	CLIP-seq
MIRT1263115	hsa-miR-129-5p	CLIP-seq
MIRT1263116	hsa-miR-1301	CLIP-seq
MIRT1263117	hsa-miR-139-5p	CLIP-seq
MIRT1263118	hsa-miR-141	CLIP-seq
MIRT1263119	hsa-miR-144	CLIP-seq
MIRT1263120	hsa-miR-1470	CLIP-seq
MIRT1263121	hsa-miR-181a	CLIP-seq
MIRT1263122	hsa-miR-181b	CLIP-seq
MIRT1263123	hsa-miR-181c	CLIP-seq
MIRT1263124	hsa-miR-181d	CLIP-seq
MIRT1263125	hsa-miR-182	CLIP-seq
MIRT1263126	hsa-miR-186	CLIP-seq
MIRT1263127	hsa-miR-200a	CLIP-seq
MIRT1263128	hsa-miR-205	CLIP-seq
MIRT1263129	hsa-miR-216a	CLIP-seq
MIRT1263130	hsa-miR-2278	CLIP-seq
MIRT1263131	hsa-miR-23a	CLIP-seq
MIRT1263132	hsa-miR-23b	CLIP-seq
MIRT1263133	hsa-miR-23c	CLIP-seq
MIRT1263134	hsa-miR-25	CLIP-seq
MIRT1263135	hsa-miR-2909	CLIP-seq
MIRT1263136	hsa-miR-300	CLIP-seq
MIRT1263137	hsa-miR-3064-3p	CLIP-seq
MIRT1263138	hsa-miR-31	CLIP-seq
MIRT1263139	hsa-miR-3121-3p	CLIP-seq
MIRT1263140	hsa-miR-3146	CLIP-seq
MIRT1263141	hsa-miR-3151	CLIP-seq
MIRT1263142	hsa-miR-3153	CLIP-seq
MIRT1263143	hsa-miR-3180-5p	CLIP-seq
MIRT1263144	hsa-miR-3192	CLIP-seq
MIRT1263145	hsa-miR-32	CLIP-seq
MIRT1263146	hsa-miR-326	CLIP-seq
MIRT1263147	hsa-miR-329	CLIP-seq
MIRT1263148	hsa-miR-330-5p	CLIP-seq
MIRT1263149	hsa-miR-331-5p	CLIP-seq
MIRT1263150	hsa-miR-361-3p	CLIP-seq
MIRT1263151	hsa-miR-362-3p	CLIP-seq
MIRT1263152	hsa-miR-362-5p	CLIP-seq
MIRT1263153	hsa-miR-363	CLIP-seq
MIRT1263154	hsa-miR-3652	CLIP-seq
MIRT1263155	hsa-miR-3663-5p	CLIP-seq
MIRT1263156	hsa-miR-367	CLIP-seq
MIRT1263157	hsa-miR-3675-3p	CLIP-seq
MIRT1263158	hsa-miR-3690	CLIP-seq
MIRT1263159	hsa-miR-369-3p	CLIP-seq
MIRT1263160	hsa-miR-371-3p	CLIP-seq
MIRT1263161	hsa-miR-371-5p	CLIP-seq
MIRT1263162	hsa-miR-371b-3p	CLIP-seq
MIRT1263163	hsa-miR-371b-5p	CLIP-seq
MIRT1263164	hsa-miR-374a	CLIP-seq
MIRT1263165	hsa-miR-374b	CLIP-seq
MIRT1263166	hsa-miR-381	CLIP-seq
MIRT1263167	hsa-miR-3914	CLIP-seq
MIRT1263168	hsa-miR-3919	CLIP-seq
MIRT1263169	hsa-miR-3925-5p	CLIP-seq
MIRT1263170	hsa-miR-3926	CLIP-seq
MIRT1263171	hsa-miR-3938	CLIP-seq
MIRT1263172	hsa-miR-3978	CLIP-seq
MIRT1263173	hsa-miR-4252	CLIP-seq
MIRT1263174	hsa-miR-4255	CLIP-seq
MIRT1263175	hsa-miR-4261	CLIP-seq
MIRT1263176	hsa-miR-4262	CLIP-seq
MIRT1263177	hsa-miR-4277	CLIP-seq
MIRT1263178	hsa-miR-4278	CLIP-seq
MIRT1263179	hsa-miR-4282	CLIP-seq
MIRT1263180	hsa-miR-4283	CLIP-seq
MIRT1263181	hsa-miR-4287	CLIP-seq
MIRT1263182	hsa-miR-4289	CLIP-seq
MIRT1263183	hsa-miR-4314	CLIP-seq
MIRT1263184	hsa-miR-4320	CLIP-seq
MIRT1263185	hsa-miR-4422	CLIP-seq
MIRT1263186	hsa-miR-4430	CLIP-seq
MIRT1263187	hsa-miR-4432	CLIP-seq
MIRT1263188	hsa-miR-4457	CLIP-seq
MIRT1263189	hsa-miR-4459	CLIP-seq
MIRT1263190	hsa-miR-4469	CLIP-seq
MIRT1263191	hsa-miR-4473	CLIP-seq
MIRT1263192	hsa-miR-4489	CLIP-seq
MIRT1263193	hsa-miR-4492	CLIP-seq
MIRT1263194	hsa-miR-4498	CLIP-seq
MIRT1263195	hsa-miR-4638-3p	CLIP-seq
MIRT1263196	hsa-miR-4643	CLIP-seq
MIRT1263197	hsa-miR-4646-5p	CLIP-seq
MIRT1263198	hsa-miR-4651	CLIP-seq
MIRT1263199	hsa-miR-466	CLIP-seq
MIRT1263200	hsa-miR-4662a-5p	CLIP-seq
MIRT1263201	hsa-miR-4666-3p	CLIP-seq
MIRT1263202	hsa-miR-4667-3p	CLIP-seq
MIRT1263203	hsa-miR-4668-5p	CLIP-seq
MIRT1263204	hsa-miR-4671-3p	CLIP-seq
MIRT1263205	hsa-miR-4685-3p	CLIP-seq
MIRT1263206	hsa-miR-4688	CLIP-seq
MIRT1263207	hsa-miR-4700-3p	CLIP-seq
MIRT1263208	hsa-miR-4712-3p	CLIP-seq
MIRT1263209	hsa-miR-4715-3p	CLIP-seq
MIRT1263210	hsa-miR-4731-3p	CLIP-seq
MIRT1263211	hsa-miR-4766-5p	CLIP-seq
MIRT1263212	hsa-miR-4773	CLIP-seq
MIRT1263213	hsa-miR-4776-3p	CLIP-seq
MIRT1263214	hsa-miR-4789-3p	CLIP-seq
MIRT1263215	hsa-miR-4789-5p	CLIP-seq
MIRT1263216	hsa-miR-4790-3p	CLIP-seq
MIRT1263217	hsa-miR-4795-3p	CLIP-seq
MIRT1263218	hsa-miR-4797-5p	CLIP-seq
MIRT1263219	hsa-miR-4801	CLIP-seq
MIRT1263220	hsa-miR-486-3p	CLIP-seq
MIRT1263221	hsa-miR-491-3p	CLIP-seq
MIRT1263222	hsa-miR-494	CLIP-seq
MIRT1263223	hsa-miR-496	CLIP-seq
MIRT1263224	hsa-miR-499-5p	CLIP-seq
MIRT1263225	hsa-miR-500b	CLIP-seq
MIRT1263226	hsa-miR-501-5p	CLIP-seq
MIRT1263227	hsa-miR-5047	CLIP-seq
MIRT1263228	hsa-miR-513b	CLIP-seq
MIRT1263229	hsa-miR-515-3p	CLIP-seq
MIRT1263230	hsa-miR-519e	CLIP-seq
MIRT1263231	hsa-miR-520a-5p	CLIP-seq
MIRT1263232	hsa-miR-525-5p	CLIP-seq
MIRT1263233	hsa-miR-545	CLIP-seq
MIRT1263234	hsa-miR-548c-3p	CLIP-seq
MIRT1263235	hsa-miR-548s	CLIP-seq
MIRT1263236	hsa-miR-589	CLIP-seq
MIRT1263237	hsa-miR-598	CLIP-seq
MIRT1263238	hsa-miR-600	CLIP-seq
MIRT1263239	hsa-miR-608	CLIP-seq
MIRT1263240	hsa-miR-616	CLIP-seq
MIRT1263241	hsa-miR-619	CLIP-seq
MIRT1263242	hsa-miR-670	CLIP-seq
MIRT1263243	hsa-miR-762	CLIP-seq
MIRT1263244	hsa-miR-875-3p	CLIP-seq
MIRT1263245	hsa-miR-92a	CLIP-seq
MIRT1263246	hsa-miR-92b	CLIP-seq
MIRT1263247	hsa-miR-96	CLIP-seq
MIRT2077448	hsa-miR-1	CLIP-seq
MIRT1263109	hsa-miR-103a	CLIP-seq
MIRT1263110	hsa-miR-105	CLIP-seq
MIRT1263111	hsa-miR-1207-3p	CLIP-seq
MIRT1263113	hsa-miR-1227	CLIP-seq
MIRT2077449	hsa-miR-1323	CLIP-seq
MIRT1263118	hsa-miR-141	CLIP-seq
MIRT2077450	hsa-miR-146a	CLIP-seq
MIRT2077451	hsa-miR-146b-5p	CLIP-seq
MIRT2077452	hsa-miR-1911	CLIP-seq
MIRT2077453	hsa-miR-199a-3p	CLIP-seq
MIRT2077454	hsa-miR-199b-3p	CLIP-seq
MIRT1263127	hsa-miR-200a	CLIP-seq
MIRT2077455	hsa-miR-206	CLIP-seq
MIRT1263129	hsa-miR-216a	CLIP-seq
MIRT1263135	hsa-miR-2909	CLIP-seq
MIRT1263137	hsa-miR-3064-3p	CLIP-seq
MIRT1263138	hsa-miR-31	CLIP-seq
MIRT2077456	hsa-miR-3129-5p	CLIP-seq
MIRT2077457	hsa-miR-3148	CLIP-seq
MIRT1263142	hsa-miR-3153	CLIP-seq
MIRT2077458	hsa-miR-3673	CLIP-seq
MIRT1263159	hsa-miR-369-3p	CLIP-seq
MIRT1263161	hsa-miR-371-5p	CLIP-seq
MIRT1263163	hsa-miR-371b-5p	CLIP-seq
MIRT1263164	hsa-miR-374a	CLIP-seq
MIRT1263165	hsa-miR-374b	CLIP-seq
MIRT2077459	hsa-miR-376a	CLIP-seq
MIRT2077460	hsa-miR-376b	CLIP-seq
MIRT2077461	hsa-miR-377	CLIP-seq
MIRT1263169	hsa-miR-3925-5p	CLIP-seq
MIRT1263173	hsa-miR-4252	CLIP-seq
MIRT1263178	hsa-miR-4278	CLIP-seq
MIRT1263179	hsa-miR-4282	CLIP-seq
MIRT1263188	hsa-miR-4457	CLIP-seq
MIRT2077462	hsa-miR-4517	CLIP-seq
MIRT2077463	hsa-miR-4633-5p	CLIP-seq
MIRT1263196	hsa-miR-4643	CLIP-seq
MIRT1263197	hsa-miR-4646-5p	CLIP-seq
MIRT2077464	hsa-miR-4652-3p	CLIP-seq
MIRT1263203	hsa-miR-4668-5p	CLIP-seq
MIRT1263206	hsa-miR-4688	CLIP-seq
MIRT1263209	hsa-miR-4715-3p	CLIP-seq
MIRT1263213	hsa-miR-4776-3p	CLIP-seq
MIRT1263216	hsa-miR-4790-3p	CLIP-seq
MIRT1263218	hsa-miR-4797-5p	CLIP-seq
MIRT1263220	hsa-miR-486-3p	CLIP-seq
MIRT1263222	hsa-miR-494	CLIP-seq
MIRT2077465	hsa-miR-5096	CLIP-seq
MIRT1263228	hsa-miR-513b	CLIP-seq
MIRT2077466	hsa-miR-532-5p	CLIP-seq
MIRT2077467	hsa-miR-548a-3p	CLIP-seq
MIRT2077468	hsa-miR-548e	CLIP-seq
MIRT2077469	hsa-miR-548f	CLIP-seq
MIRT2077470	hsa-miR-548o	CLIP-seq
MIRT2077471	hsa-miR-561	CLIP-seq
MIRT2077472	hsa-miR-613	CLIP-seq
MIRT2077473	hsa-miR-875-5p	CLIP-seq
MIRT2077474	hsa-miR-944	CLIP-seq
MIRT2077448	hsa-miR-1	CLIP-seq
MIRT1263108	hsa-miR-101	CLIP-seq
MIRT1263109	hsa-miR-103a	CLIP-seq
MIRT1263110	hsa-miR-105	CLIP-seq
MIRT1263111	hsa-miR-1207-3p	CLIP-seq
MIRT1263113	hsa-miR-1227	CLIP-seq
MIRT2304017	hsa-miR-1245b-5p	CLIP-seq
MIRT2304018	hsa-miR-1246	CLIP-seq
MIRT2304019	hsa-miR-1248	CLIP-seq
MIRT1263114	hsa-miR-1271	CLIP-seq
MIRT1263116	hsa-miR-1301	CLIP-seq
MIRT1263118	hsa-miR-141	CLIP-seq
MIRT1263119	hsa-miR-144	CLIP-seq
MIRT1263121	hsa-miR-181a	CLIP-seq
MIRT1263122	hsa-miR-181b	CLIP-seq
MIRT1263123	hsa-miR-181c	CLIP-seq
MIRT1263124	hsa-miR-181d	CLIP-seq
MIRT1263125	hsa-miR-182	CLIP-seq
MIRT1263127	hsa-miR-200a	CLIP-seq
MIRT2077455	hsa-miR-206	CLIP-seq
MIRT1263131	hsa-miR-23a	CLIP-seq
MIRT1263132	hsa-miR-23b	CLIP-seq
MIRT1263133	hsa-miR-23c	CLIP-seq
MIRT1263134	hsa-miR-25	CLIP-seq
MIRT1263137	hsa-miR-3064-3p	CLIP-seq
MIRT1263138	hsa-miR-31	CLIP-seq
MIRT2304020	hsa-miR-3127-3p	CLIP-seq
MIRT2304021	hsa-miR-3130-3p	CLIP-seq
MIRT2304022	hsa-miR-3142	CLIP-seq
MIRT1263142	hsa-miR-3153	CLIP-seq
MIRT1263144	hsa-miR-3192	CLIP-seq
MIRT1263145	hsa-miR-32	CLIP-seq
MIRT1263146	hsa-miR-326	CLIP-seq
MIRT1263148	hsa-miR-330-5p	CLIP-seq
MIRT1263149	hsa-miR-331-5p	CLIP-seq
MIRT1263153	hsa-miR-363	CLIP-seq
MIRT1263156	hsa-miR-367	CLIP-seq
MIRT2077458	hsa-miR-3673	CLIP-seq
MIRT1263158	hsa-miR-3690	CLIP-seq
MIRT2304023	hsa-miR-3692	CLIP-seq
MIRT1263160	hsa-miR-371-3p	CLIP-seq
MIRT1263162	hsa-miR-371b-3p	CLIP-seq
MIRT1263171	hsa-miR-3938	CLIP-seq
MIRT1263173	hsa-miR-4252	CLIP-seq
MIRT2304024	hsa-miR-4259	CLIP-seq
MIRT1263175	hsa-miR-4261	CLIP-seq
MIRT1263176	hsa-miR-4262	CLIP-seq
MIRT1263177	hsa-miR-4277	CLIP-seq
MIRT2304025	hsa-miR-4294	CLIP-seq
MIRT1263183	hsa-miR-4314	CLIP-seq
MIRT1263184	hsa-miR-4320	CLIP-seq
MIRT1263188	hsa-miR-4457	CLIP-seq
MIRT1263191	hsa-miR-4473	CLIP-seq
MIRT1263195	hsa-miR-4638-3p	CLIP-seq
MIRT1263196	hsa-miR-4643	CLIP-seq
MIRT1263197	hsa-miR-4646-5p	CLIP-seq
MIRT2304026	hsa-miR-4650-5p	CLIP-seq
MIRT2304027	hsa-miR-4659a-5p	CLIP-seq
MIRT2304028	hsa-miR-4659b-5p	CLIP-seq
MIRT1263199	hsa-miR-466	CLIP-seq
MIRT1263203	hsa-miR-4668-5p	CLIP-seq
MIRT1263204	hsa-miR-4671-3p	CLIP-seq
MIRT1263209	hsa-miR-4715-3p	CLIP-seq
MIRT2304029	hsa-miR-4715-5p	CLIP-seq
MIRT1263213	hsa-miR-4776-3p	CLIP-seq
MIRT1263214	hsa-miR-4789-3p	CLIP-seq
MIRT1263216	hsa-miR-4790-3p	CLIP-seq
MIRT2304030	hsa-miR-4793-3p	CLIP-seq
MIRT1263217	hsa-miR-4795-3p	CLIP-seq
MIRT1263218	hsa-miR-4797-5p	CLIP-seq
MIRT2304031	hsa-miR-485-3p	CLIP-seq
MIRT1263220	hsa-miR-486-3p	CLIP-seq
MIRT1263222	hsa-miR-494	CLIP-seq
MIRT1263223	hsa-miR-496	CLIP-seq
MIRT1263226	hsa-miR-501-5p	CLIP-seq
MIRT1263227	hsa-miR-5047	CLIP-seq
MIRT1263228	hsa-miR-513b	CLIP-seq
MIRT1263229	hsa-miR-515-3p	CLIP-seq
MIRT1263230	hsa-miR-519e	CLIP-seq
MIRT1263233	hsa-miR-545	CLIP-seq
MIRT1263238	hsa-miR-600	CLIP-seq
MIRT2077472	hsa-miR-613	CLIP-seq
MIRT1263241	hsa-miR-619	CLIP-seq
MIRT2077473	hsa-miR-875-5p	CLIP-seq
MIRT2304032	hsa-miR-891a	CLIP-seq
MIRT2304033	hsa-miR-924	CLIP-seq
MIRT1263245	hsa-miR-92a	CLIP-seq
MIRT1263246	hsa-miR-92b	CLIP-seq
MIRT2304034	hsa-miR-942	CLIP-seq
MIRT1263247	hsa-miR-96	CLIP-seq
MIRT2077449	hsa-miR-1323	CLIP-seq
MIRT2077457	hsa-miR-3148	CLIP-seq
MIRT2304023	hsa-miR-3692	CLIP-seq
MIRT2393025	hsa-miR-4443	CLIP-seq
MIRT1263218	hsa-miR-4797-5p	CLIP-seq
MIRT2077465	hsa-miR-5096	CLIP-seq
MIRT2077470	hsa-miR-548o	CLIP-seq
MIRT2393026	hsa-miR-765	CLIP-seq
MIRT1263134	hsa-miR-25	CLIP-seq
MIRT1263145	hsa-miR-32	CLIP-seq
MIRT1263153	hsa-miR-363	CLIP-seq
MIRT1263156	hsa-miR-367	CLIP-seq
MIRT1263158	hsa-miR-3690	CLIP-seq
MIRT1263195	hsa-miR-4638-3p	CLIP-seq
MIRT1263217	hsa-miR-4795-3p	CLIP-seq
MIRT1263218	hsa-miR-4797-5p	CLIP-seq
MIRT1263223	hsa-miR-496	CLIP-seq
MIRT1263241	hsa-miR-619	CLIP-seq
MIRT1263245	hsa-miR-92a	CLIP-seq
MIRT1263246	hsa-miR-92b	CLIP-seq
MIRT1263108	hsa-miR-101	CLIP-seq
MIRT1263112	hsa-miR-1208	CLIP-seq
MIRT2600907	hsa-miR-1226	CLIP-seq
MIRT2600908	hsa-miR-1237	CLIP-seq
MIRT1263114	hsa-miR-1271	CLIP-seq
MIRT1263117	hsa-miR-139-5p	CLIP-seq
MIRT1263118	hsa-miR-141	CLIP-seq
MIRT1263119	hsa-miR-144	CLIP-seq
MIRT1263121	hsa-miR-181a	CLIP-seq
MIRT1263122	hsa-miR-181b	CLIP-seq
MIRT1263123	hsa-miR-181c	CLIP-seq
MIRT1263124	hsa-miR-181d	CLIP-seq
MIRT1263125	hsa-miR-182	CLIP-seq
MIRT2600909	hsa-miR-188-5p	CLIP-seq
MIRT1263127	hsa-miR-200a	CLIP-seq
MIRT2600910	hsa-miR-218	CLIP-seq
MIRT2600911	hsa-miR-219-1-3p	CLIP-seq
MIRT1263131	hsa-miR-23a	CLIP-seq
MIRT1263132	hsa-miR-23b	CLIP-seq
MIRT1263133	hsa-miR-23c	CLIP-seq
MIRT1263134	hsa-miR-25	CLIP-seq
MIRT1263139	hsa-miR-3121-3p	CLIP-seq
MIRT2600912	hsa-miR-3123	CLIP-seq
MIRT2600913	hsa-miR-3138	CLIP-seq
MIRT2600914	hsa-miR-3150b-3p	CLIP-seq
MIRT2600915	hsa-miR-3160-3p	CLIP-seq
MIRT1263144	hsa-miR-3192	CLIP-seq
MIRT1263145	hsa-miR-32	CLIP-seq
MIRT2600916	hsa-miR-339-3p	CLIP-seq
MIRT1263150	hsa-miR-361-3p	CLIP-seq
MIRT1263153	hsa-miR-363	CLIP-seq
MIRT1263155	hsa-miR-3663-5p	CLIP-seq
MIRT1263156	hsa-miR-367	CLIP-seq
MIRT1263157	hsa-miR-3675-3p	CLIP-seq
MIRT2600917	hsa-miR-3689a-3p	CLIP-seq
MIRT2600918	hsa-miR-3689c	CLIP-seq
MIRT2600919	hsa-miR-3689d	CLIP-seq
MIRT1263158	hsa-miR-3690	CLIP-seq
MIRT1263159	hsa-miR-369-3p	CLIP-seq
MIRT1263164	hsa-miR-374a	CLIP-seq
MIRT1263165	hsa-miR-374b	CLIP-seq
MIRT2077459	hsa-miR-376a	CLIP-seq
MIRT2077460	hsa-miR-376b	CLIP-seq
MIRT2077461	hsa-miR-377	CLIP-seq
MIRT2600920	hsa-miR-3925-3p	CLIP-seq
MIRT1263172	hsa-miR-3978	CLIP-seq
MIRT1263176	hsa-miR-4262	CLIP-seq
MIRT2600921	hsa-miR-4299	CLIP-seq
MIRT2600922	hsa-miR-4300	CLIP-seq
MIRT2600923	hsa-miR-4311	CLIP-seq
MIRT1263183	hsa-miR-4314	CLIP-seq
MIRT1263189	hsa-miR-4459	CLIP-seq
MIRT2600924	hsa-miR-4474-5p	CLIP-seq
MIRT2600925	hsa-miR-4523	CLIP-seq
MIRT1263195	hsa-miR-4638-3p	CLIP-seq
MIRT1263196	hsa-miR-4643	CLIP-seq
MIRT1263197	hsa-miR-4646-5p	CLIP-seq
MIRT2077464	hsa-miR-4652-3p	CLIP-seq
MIRT2304027	hsa-miR-4659a-5p	CLIP-seq
MIRT2304028	hsa-miR-4659b-5p	CLIP-seq
MIRT1263199	hsa-miR-466	CLIP-seq
MIRT2600926	hsa-miR-4662a-3p	CLIP-seq
MIRT2600927	hsa-miR-4663	CLIP-seq
MIRT2600928	hsa-miR-4671-5p	CLIP-seq
MIRT1263207	hsa-miR-4700-3p	CLIP-seq
MIRT2600929	hsa-miR-4710	CLIP-seq
MIRT1263209	hsa-miR-4715-3p	CLIP-seq
MIRT2600930	hsa-miR-4716-3p	CLIP-seq
MIRT2600931	hsa-miR-4723-5p	CLIP-seq
MIRT2600932	hsa-miR-4728-5p	CLIP-seq
MIRT2600933	hsa-miR-4733-3p	CLIP-seq
MIRT2600934	hsa-miR-4738-3p	CLIP-seq
MIRT2600935	hsa-miR-4768-5p	CLIP-seq
MIRT1263213	hsa-miR-4776-3p	CLIP-seq
MIRT2600936	hsa-miR-4784	CLIP-seq
MIRT1263214	hsa-miR-4789-3p	CLIP-seq
MIRT2600937	hsa-miR-4792	CLIP-seq
MIRT1263217	hsa-miR-4795-3p	CLIP-seq
MIRT1263218	hsa-miR-4797-5p	CLIP-seq
MIRT1263220	hsa-miR-486-3p	CLIP-seq
MIRT1263222	hsa-miR-494	CLIP-seq
MIRT1263223	hsa-miR-496	CLIP-seq
MIRT1263226	hsa-miR-501-5p	CLIP-seq
MIRT2600938	hsa-miR-508-5p	CLIP-seq
MIRT2600939	hsa-miR-548b-3p	CLIP-seq
MIRT2600940	hsa-miR-571	CLIP-seq
MIRT2600941	hsa-miR-577	CLIP-seq
MIRT1263241	hsa-miR-619	CLIP-seq
MIRT2600942	hsa-miR-627	CLIP-seq
MIRT2600943	hsa-miR-636	CLIP-seq
MIRT2600944	hsa-miR-661	CLIP-seq
MIRT2393026	hsa-miR-765	CLIP-seq
MIRT2600945	hsa-miR-766	CLIP-seq
MIRT1263244	hsa-miR-875-3p	CLIP-seq
MIRT2600946	hsa-miR-888	CLIP-seq
MIRT2600947	hsa-miR-920	CLIP-seq
MIRT2304033	hsa-miR-924	CLIP-seq
MIRT1263245	hsa-miR-92a	CLIP-seq
MIRT1263246	hsa-miR-92b	CLIP-seq
MIRT2077474	hsa-miR-944	CLIP-seq
MIRT1263247	hsa-miR-96	CLIP-seq
MIRT1263108	hsa-miR-101	CLIP-seq
MIRT1263112	hsa-miR-1208	CLIP-seq
MIRT2600907	hsa-miR-1226	CLIP-seq
MIRT2600908	hsa-miR-1237	CLIP-seq
MIRT1263117	hsa-miR-139-5p	CLIP-seq
MIRT1263118	hsa-miR-141	CLIP-seq
MIRT1263119	hsa-miR-144	CLIP-seq
MIRT1263121	hsa-miR-181a	CLIP-seq
MIRT1263122	hsa-miR-181b	CLIP-seq
MIRT1263123	hsa-miR-181c	CLIP-seq
MIRT1263124	hsa-miR-181d	CLIP-seq
MIRT1263127	hsa-miR-200a	CLIP-seq
MIRT2600910	hsa-miR-218	CLIP-seq
MIRT1263131	hsa-miR-23a	CLIP-seq
MIRT1263132	hsa-miR-23b	CLIP-seq
MIRT1263133	hsa-miR-23c	CLIP-seq
MIRT2600916	hsa-miR-339-3p	CLIP-seq
MIRT1263155	hsa-miR-3663-5p	CLIP-seq
MIRT2600917	hsa-miR-3689a-3p	CLIP-seq
MIRT2600918	hsa-miR-3689c	CLIP-seq
MIRT2600919	hsa-miR-3689d	CLIP-seq
MIRT1263176	hsa-miR-4262	CLIP-seq
MIRT2600921	hsa-miR-4299	CLIP-seq
MIRT1263189	hsa-miR-4459	CLIP-seq
MIRT2600925	hsa-miR-4523	CLIP-seq
MIRT1263196	hsa-miR-4643	CLIP-seq
MIRT2077464	hsa-miR-4652-3p	CLIP-seq
MIRT1263199	hsa-miR-466	CLIP-seq
MIRT1263207	hsa-miR-4700-3p	CLIP-seq
MIRT2600929	hsa-miR-4710	CLIP-seq
MIRT2600930	hsa-miR-4716-3p	CLIP-seq
MIRT2600931	hsa-miR-4723-5p	CLIP-seq
MIRT2600932	hsa-miR-4728-5p	CLIP-seq
MIRT2600933	hsa-miR-4733-3p	CLIP-seq
MIRT1263214	hsa-miR-4789-3p	CLIP-seq
MIRT2600937	hsa-miR-4792	CLIP-seq
MIRT1263222	hsa-miR-494	CLIP-seq
MIRT1263226	hsa-miR-501-5p	CLIP-seq
MIRT2600939	hsa-miR-548b-3p	CLIP-seq
MIRT2600942	hsa-miR-627	CLIP-seq
MIRT2600943	hsa-miR-636	CLIP-seq
MIRT2393026	hsa-miR-765	CLIP-seq
MIRT2304033	hsa-miR-924	CLIP-seq

Show/Hide all (3)

Transcription factor	Regulation	Reference
PAX5	Unknown	9190940
SP1	Repression	24825907
STAT1	Repression	24825907

Show/Hide all (96)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000165	Process	MAPK cascade	IEA
GO:0000166	Function	Nucleotide binding	IEA
GO:0002281	Process	Macrophage activation involved in immune response	IEA
GO:0002376	Process	Immune system process	IEA
GO:0003785	Function	Actin monomer binding	IEA
GO:0003785	Function	Actin monomer binding	ISS
GO:0004672	Function	Protein kinase activity	IDA	19542546, 34593629
GO:0004672	Function	Protein kinase activity	IEA
GO:0004674	Function	Protein serine/threonine kinase activity	IBA
GO:0004674	Function	Protein serine/threonine kinase activity	IDA	15695813
GO:0004674	Function	Protein serine/threonine kinase activity	IEA
GO:0004697	Function	Diacylglycerol-dependent serine/threonine kinase activity	IEA
GO:0004697	Function	Diacylglycerol-dependent serine/threonine kinase activity	TAS	1382605
GO:0004699	Function	Diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	IDA	18556656
GO:0004699	Function	Diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	IEA
GO:0005515	Function	Protein binding	IPI	16810323, 19542546, 19662078, 20353823, 21625473, 22939624, 24996056, 28934384, 31980649, 32814053, 34593629, 36931259
GO:0005524	Function	ATP binding	IEA
GO:0005634	Component	Nucleus	IEA
GO:0005737	Component	Cytoplasm	IDA	15632189, 19542546
GO:0005737	Component	Cytoplasm	IEA
GO:0005739	Component	Mitochondrion	IEA
GO:0005783	Component	Endoplasmic reticulum	IDA	18556656
GO:0005794	Component	Golgi apparatus	IEA
GO:0005794	Component	Golgi apparatus	ISS
GO:0005829	Component	Cytosol	IDA	17603037
GO:0005829	Component	Cytosol	IEA
GO:0005829	Component	Cytosol	TAS
GO:0005856	Component	Cytoskeleton	IEA
GO:0005886	Component	Plasma membrane	IDA	15632189, 17603037
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0006915	Process	Apoptotic process	TAS	10438519
GO:0007155	Process	Cell adhesion	IEA
GO:0007165	Process	Signal transduction	IEA
GO:0007165	Process	Signal transduction	TAS	1382605
GO:0008047	Function	Enzyme activator activity	IMP	18556656
GO:0008270	Function	Zinc ion binding	IEA
GO:0009407	Process	Toxin catabolic process	IDA	18556656
GO:0010634	Process	Positive regulation of epithelial cell migration	IMP	17603037
GO:0010763	Process	Positive regulation of fibroblast migration	IEA
GO:0010763	Process	Positive regulation of fibroblast migration	ISS
GO:0010811	Process	Positive regulation of cell-substrate adhesion	IEA
GO:0010959	Process	Regulation of metal ion transport	IEA
GO:0016020	Component	Membrane	IEA
GO:0016301	Function	Kinase activity	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0018105	Process	Peptidyl-serine phosphorylation	IDA	15695813
GO:0019216	Process	Regulation of lipid metabolic process	IEA
GO:0019899	Function	Enzyme binding	IPI	15632189, 18556656
GO:0030073	Process	Insulin secretion	IEA
GO:0030546	Function	Signaling receptor activator activity	IEA
GO:0030838	Process	Positive regulation of actin filament polymerization	IEA
GO:0030838	Process	Positive regulation of actin filament polymerization	ISS
GO:0031397	Process	Negative regulation of protein ubiquitination	IEA
GO:0031589	Process	Cell-substrate adhesion	IEA
GO:0031663	Process	Lipopolysaccharide-mediated signaling pathway	IEA
GO:0031663	Process	Lipopolysaccharide-mediated signaling pathway	ISS
GO:0032024	Process	Positive regulation of insulin secretion	IEA
GO:0032230	Process	Positive regulation of synaptic transmission, GABAergic	IEA
GO:0032467	Process	Positive regulation of cytokinesis	IMP	18604201
GO:0032930	Process	Positive regulation of superoxide anion generation	TAS	19193863
GO:0035276	Function	Ethanol binding	IEA
GO:0035556	Process	Intracellular signal transduction	IBA
GO:0035641	Process	Locomotory exploration behavior	IEA
GO:0035669	Process	TRAM-dependent toll-like receptor 4 signaling pathway	IEA
GO:0035669	Process	TRAM-dependent toll-like receptor 4 signaling pathway	ISS
GO:0038096	Process	Fc-gamma receptor signaling pathway involved in phagocytosis	TAS
GO:0042178	Process	Xenobiotic catabolic process	IMP	18556656
GO:0043123	Process	Positive regulation of canonical NF-kappaB signal transduction	IEA
GO:0043278	Process	Response to morphine	IEA
GO:0043410	Process	Positive regulation of MAPK cascade	IEA
GO:0045111	Component	Intermediate filament cytoskeleton	IDA
GO:0045202	Component	Synapse	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0048471	Component	Perinuclear region of cytoplasm	IEA
GO:0048471	Component	Perinuclear region of cytoplasm	ISS
GO:0050996	Process	Positive regulation of lipid catabolic process	IEA
GO:0051279	Process	Regulation of release of sequestered calcium ion into cytosol	IEA
GO:0051301	Process	Cell division	IEA
GO:0051649	Process	Establishment of localization in cell	IEA
GO:0051932	Process	Synaptic transmission, GABAergic	IEA
GO:0061178	Process	Regulation of insulin secretion involved in cellular response to glucose stimulus	IEA
GO:0070254	Process	Mucus secretion	IEA
GO:0070257	Process	Positive regulation of mucus secretion	IEA
GO:0071361	Process	Cellular response to ethanol	IEA
GO:0071380	Process	Cellular response to prostaglandin E stimulus	IEA
GO:0071456	Process	Cellular response to hypoxia	IEA
GO:0071889	Function	14-3-3 protein binding	IEA
GO:0071944	Component	Cell periphery	IEA
GO:0071944	Component	Cell periphery	ISS
GO:0090303	Process	Positive regulation of wound healing	IMP	17603037
GO:0106310	Function	Protein serine kinase activity	IEA
GO:1902306	Process	Negative regulation of sodium ion transmembrane transport	TAS	19193863
GO:1903078	Process	Positive regulation of protein localization to plasma membrane	IEA
GO:1903078	Process	Positive regulation of protein localization to plasma membrane	TAS	22732145
GO:1904062	Process	Regulation of monoatomic cation transmembrane transport	IEA

MIM	HGNC	e!Ensembl
176975	9401	ENSG00000171132

Q02156

Protein name

Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)

Protein function

Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, m

PDB

2WH0 , 5LIH

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00168	C2	6 → 119	C2 domain	Domain
PF00130	C1_1	170 → 223	Phorbol esters/diacylglycerol binding domain (C1 domain)	Domain
PF00130	C1_1	243 → 295	Phorbol esters/diacylglycerol binding domain (C1 domain)	Domain
PF00069	Pkinase	408 → 668	Protein kinase domain	Domain
PF00433	Pkinase_C	689 → 730	Protein kinase C terminal domain	Family

Tissue specificity

TISSUE SPECIFICITY: Expressed in cumulus cells (at protein level). {ECO:0000269|PubMed:19542546}.

Sequence

MVVFNGLLKIKICEAVSLKPTAWSLRHAVGPRPQTFLLDPYIALNVDDSRIGQTATKQKT
NSPAWHDEFVTDVCNGRKIELAVFHDAPIGYDDFVANCTIQFEELLQNGSRHFEDWIDLE
PEGRVYVIIDLSGSSGEAPKDNEERVFRERMRPRKRQGAVRRRVHQVNGHKFMATYLRQP
TYCSHCRDFIWGVIGKQGYQCQVCTCVVHKRCHELIITKCAGLKKQETPDQVGSQRFSVN
MPHKFGIHNYKVPTFCDHCGSLLWGLLRQGLQCKVCKMNVHRRCETNVAPNCGVDARGIA
KVLADLGVTPDKITNSGQRRKKLIAGAESPQPASGSSPSEEDRSKSAPTSPCDQEIKELE
NNIRKALSFDNRGEEHRAASSPDGQLMSPGENGEVRQGQAKRLGLDEFNFIKVLGKGSFG
KVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALARKHPYLTQLYCCFQTKD
RLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRDLKLDNILL
DAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEM
MAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTKNPHKRLGCVASQNGED
AIKQHPFFKEIDWVLLEQKKIKPPFKPRIKTKRDVNNFDQDFTREEPVLTLVDEAIVKQI
NQEEFKGFSYFGEDLMP

Sequence length

737

Interactions

View interactions

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
See cases	Uncertain significance	rs765421914	RCV001198560

Show/Hide Text Mining Associations (67)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Adenocarcinoma of Lung	Associate	32741804
Alzheimer Disease	Associate	24848988, 34062866
Amyotrophic Lateral Sclerosis	Inhibit	37629005
Arthritis Psoriatic	Stimulate	29280140
Autism Spectrum Disorder	Associate	38057311
Blood Coagulation Disorders	Associate	35039944
Brain Diseases	Associate	35577881
Brain Neoplasms	Stimulate	35577881
Breast Neoplasms	Associate	12628005, 16785234, 19633292, 21720730, 23562764, 24825907, 32549199, 33490232, 34433666
Calcinosis Cutis	Associate	1988168
Carcinogenesis	Associate	32429937, 9683604
Carcinoma Hepatocellular	Associate	36782184
Carcinoma Non Small Cell Lung	Associate	12121973, 24070896, 31648598, 36897674
Carcinoma Ovarian Epithelial	Associate	26637171
Carcinoma Renal Cell	Associate	17760843, 20459627, 21955404
Carcinoma Squamous Cell	Associate	29636077
Cardiomyopathy Hypertrophic	Associate	27072078
Cartilage Diseases	Associate	27072078
COVID 19	Associate	35039944
Depressive Disorder Major	Associate	19573263
Developmental Disabilities	Associate	24372385
Diabetes Mellitus Type 2	Associate	31869513, 32993798
Diabetic Retinopathy	Associate	38194422
Epilepsy	Associate	24372385
Glioblastoma	Associate	26943771, 29439667
Glioma	Associate	16103081, 35577881
Gliosarcoma	Associate	29439667
Hashimoto Disease	Stimulate	29280140
Hearing Loss Noise Induced	Associate	30111769
Heart Arrest	Stimulate	24954177
Hypoxia	Associate	9727032
Inflammation	Associate	28286252, 38194422
Leiomyoma	Associate	35985686
Leukemia	Associate	7512966, 9727032
Leukemia Myeloid	Associate	19864212
Leukemia Myeloid Acute	Associate	18988868
Liver Failure	Stimulate	26212029
Ludwig's Angina	Associate	35577881
Lung Diseases	Associate	18342628
Lung Neoplasms	Associate	12121973, 24070896, 30923343
Lupus Erythematosus Systemic	Inhibit	15379867
Lymphoma Follicular	Associate	22102710
Melanoma	Associate	1988168, 22304920, 25728676, 7678596
Muscle Neoplasms	Associate	28286252
Myocardial Infarction	Stimulate	23071564, 30765820
Neoplasm Metastasis	Associate	24825907, 37833790
Neoplasms	Stimulate	12185081, 16508638, 24825907, 9916928
Neoplasms	Associate	15509588, 17760843, 21955404, 22381066, 25788289, 28417283, 30209539, 30923343, 31493422, 36897674, 37667176, 9683604
Nerve Degeneration	Inhibit	24848988
Neuroblastoma	Associate	15189345, 17697049, 18408015, 19077250
Neurotoxicity Syndromes	Associate	37336366
Non alcoholic Fatty Liver Disease	Associate	23931760, 29341352
Osteoarthritis	Inhibit	27072078
Ovarian Neoplasms	Associate	17678893
Ovarian Neoplasms	Inhibit	37833790
Primary Myelofibrosis	Associate	27081176
Prostatic Neoplasms	Associate	12185081, 20566643, 21824498, 23076676, 23826267, 30209539, 9916928
Prostatic Neoplasms	Stimulate	24825907
Psoriasis	Associate	29280140
Radiation Injuries	Associate	25054431
Renal Insufficiency Chronic	Associate	32046176
Small Cell Lung Carcinoma	Associate	12121973, 16810323
Squamous Cell Carcinoma of Head and Neck	Associate	17018591
Thrombocythemia Essential	Associate	27081176
Uterine Cervical Neoplasms	Associate	37667176
Uveal melanoma	Associate	22653968
Zellweger Syndrome	Associate	7535766

PRKCE (protein kinase C epsilon)