Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs Other IDs
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	5563
Gene name Gene Name - the full gene name approved by the HGNC.	Protein kinase AMP-activated catalytic subunit alpha 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	PRKAA2
Synonyms (NCBI Gene) Gene synonyms aliases	AMPK, AMPK2, AMPKa2, PRKAA
Chromosome Chromosome number	1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	1p32.2
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that

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miRTarBase ID	miRNA	Experiments	Reference
MIRT026874	hsa-miR-192-5p	Microarray	19074876
MIRT027841	hsa-miR-98-5p	Microarray	19088304
MIRT052107	hsa-let-7b-5p	CLASH	23622248
MIRT047217	hsa-miR-182-5p	CLASH	23622248
MIRT700623	hsa-miR-495-5p	HITS-CLIP	23313552
MIRT700622	hsa-miR-4761-5p	HITS-CLIP	23313552
MIRT700621	hsa-miR-8060	HITS-CLIP	23313552
MIRT700620	hsa-miR-494-3p	HITS-CLIP	23313552
MIRT700619	hsa-miR-3166	HITS-CLIP	23313552
MIRT700618	hsa-miR-4771	HITS-CLIP	23313552
MIRT700617	hsa-miR-3653-3p	HITS-CLIP	23313552
MIRT700616	hsa-miR-7154-5p	HITS-CLIP	23313552
MIRT700615	hsa-miR-1273h-3p	HITS-CLIP	23313552
MIRT700614	hsa-miR-3678-3p	HITS-CLIP	23313552
MIRT700613	hsa-miR-3658	HITS-CLIP	23313552
MIRT654776	hsa-miR-141-3p	HITS-CLIP	23824327
MIRT654775	hsa-miR-200a-3p	HITS-CLIP	23824327
MIRT654774	hsa-miR-500a-5p	HITS-CLIP	23824327
MIRT654773	hsa-miR-382-3p	HITS-CLIP	23824327
MIRT654772	hsa-miR-4719	HITS-CLIP	23824327
MIRT654771	hsa-miR-4729	HITS-CLIP	23824327
MIRT654770	hsa-miR-6734-3p	HITS-CLIP	23824327
MIRT654769	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT449658	hsa-miR-5696	HITS-CLIP	23824327
MIRT654768	hsa-miR-302c-5p	HITS-CLIP	23824327
MIRT555220	hsa-miR-7844-5p	PAR-CLIP	21572407
MIRT281967	hsa-miR-4804-3p	PAR-CLIP	21572407
MIRT281965	hsa-miR-4720-3p	PAR-CLIP	21572407
MIRT449663	hsa-miR-1250-3p	PAR-CLIP	22100165
MIRT449662	hsa-miR-153-5p	PAR-CLIP	22100165
MIRT449661	hsa-miR-26b-3p	PAR-CLIP	22100165
MIRT449660	hsa-miR-4635	PAR-CLIP	22100165
MIRT449659	hsa-miR-1206	PAR-CLIP	22100165
MIRT449657	hsa-miR-6853-3p	PAR-CLIP	22100165
MIRT449658	hsa-miR-5696	PAR-CLIP	22100165
MIRT449656	hsa-miR-579-3p	PAR-CLIP	22100165
MIRT449655	hsa-miR-664b-3p	PAR-CLIP	22100165
MIRT449654	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT449653	hsa-miR-578	PAR-CLIP	22100165
MIRT449652	hsa-miR-510-3p	PAR-CLIP	22100165
MIRT731819	hsa-miR-27a-3p	Luciferase reporter assay, Western blot	27779715
MIRT731819	hsa-miR-27a-3p	Luciferase reporter assay, Western blot	27779715
MIRT734738	hsa-miR-124-3p	Luciferase reporter assay, Microarray	33681194
MIRT700623	hsa-miR-495-5p	HITS-CLIP	23313552
MIRT700622	hsa-miR-4761-5p	HITS-CLIP	23313552
MIRT700621	hsa-miR-8060	HITS-CLIP	23313552
MIRT700620	hsa-miR-494-3p	HITS-CLIP	23313552
MIRT700619	hsa-miR-3166	HITS-CLIP	23313552
MIRT700618	hsa-miR-4771	HITS-CLIP	23313552
MIRT700617	hsa-miR-3653-3p	HITS-CLIP	23313552
MIRT700616	hsa-miR-7154-5p	HITS-CLIP	23313552
MIRT700615	hsa-miR-1273h-3p	HITS-CLIP	23313552
MIRT700614	hsa-miR-3678-3p	HITS-CLIP	23313552
MIRT700613	hsa-miR-3658	HITS-CLIP	23313552
MIRT654776	hsa-miR-141-3p	HITS-CLIP	23824327
MIRT654775	hsa-miR-200a-3p	HITS-CLIP	23824327
MIRT654774	hsa-miR-500a-5p	HITS-CLIP	23824327
MIRT654773	hsa-miR-382-3p	HITS-CLIP	23824327
MIRT654772	hsa-miR-4719	HITS-CLIP	23824327
MIRT654771	hsa-miR-4729	HITS-CLIP	23824327
MIRT654770	hsa-miR-6734-3p	HITS-CLIP	23824327
MIRT654769	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT449658	hsa-miR-5696	HITS-CLIP	23824327
MIRT654768	hsa-miR-302c-5p	HITS-CLIP	23824327
MIRT555220	hsa-miR-7844-5p	PAR-CLIP	21572407
MIRT281967	hsa-miR-4804-3p	PAR-CLIP	21572407
MIRT281965	hsa-miR-4720-3p	PAR-CLIP	21572407
MIRT449663	hsa-miR-1250-3p	PAR-CLIP	22100165
MIRT449662	hsa-miR-153-5p	PAR-CLIP	22100165
MIRT449661	hsa-miR-26b-3p	PAR-CLIP	22100165
MIRT449660	hsa-miR-4635	PAR-CLIP	22100165
MIRT449659	hsa-miR-1206	PAR-CLIP	22100165
MIRT449657	hsa-miR-6853-3p	PAR-CLIP	22100165
MIRT449658	hsa-miR-5696	PAR-CLIP	22100165
MIRT449656	hsa-miR-579-3p	PAR-CLIP	22100165
MIRT449655	hsa-miR-664b-3p	PAR-CLIP	22100165
MIRT449654	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT449653	hsa-miR-578	PAR-CLIP	22100165
MIRT449652	hsa-miR-510-3p	PAR-CLIP	22100165
MIRT739556	hsa-miR-10a	CLIP-seq
MIRT739555	hsa-miR-10b	CLIP-seq
MIRT1261931	hsa-miR-1208	CLIP-seq
MIRT1261932	hsa-miR-1265	CLIP-seq
MIRT1261933	hsa-miR-1267	CLIP-seq
MIRT1261934	hsa-miR-128	CLIP-seq
MIRT1261935	hsa-miR-1283	CLIP-seq
MIRT1261936	hsa-miR-1286	CLIP-seq
MIRT1261937	hsa-miR-1288	CLIP-seq
MIRT1261938	hsa-miR-129-5p	CLIP-seq
MIRT1261939	hsa-miR-130a	CLIP-seq
MIRT1261940	hsa-miR-130b	CLIP-seq
MIRT1261941	hsa-miR-134	CLIP-seq
MIRT1261942	hsa-miR-137	CLIP-seq
MIRT1261943	hsa-miR-1827	CLIP-seq
MIRT1261944	hsa-miR-186	CLIP-seq
MIRT1261945	hsa-miR-1915	CLIP-seq
MIRT739557	hsa-miR-203	CLIP-seq
MIRT1261946	hsa-miR-2053	CLIP-seq
MIRT1261947	hsa-miR-214	CLIP-seq
MIRT1261948	hsa-miR-216b	CLIP-seq
MIRT1261949	hsa-miR-218	CLIP-seq
MIRT1261950	hsa-miR-2392	CLIP-seq
MIRT1261951	hsa-miR-25	CLIP-seq
MIRT1261952	hsa-miR-27a	CLIP-seq
MIRT1261953	hsa-miR-27b	CLIP-seq
MIRT1261954	hsa-miR-301a	CLIP-seq
MIRT1261955	hsa-miR-301b	CLIP-seq
MIRT1261956	hsa-miR-3118	CLIP-seq
MIRT1261957	hsa-miR-3157-3p	CLIP-seq
MIRT1261958	hsa-miR-3164	CLIP-seq
MIRT1261959	hsa-miR-3169	CLIP-seq
MIRT1261960	hsa-miR-3173-3p	CLIP-seq
MIRT1261961	hsa-miR-32	CLIP-seq
MIRT1261962	hsa-miR-320a	CLIP-seq
MIRT1261963	hsa-miR-320b	CLIP-seq
MIRT1261964	hsa-miR-320c	CLIP-seq
MIRT1261965	hsa-miR-320d	CLIP-seq
MIRT1261966	hsa-miR-323-3p	CLIP-seq
MIRT1261967	hsa-miR-330-3p	CLIP-seq
MIRT1261968	hsa-miR-335	CLIP-seq
MIRT1261969	hsa-miR-34c-3p	CLIP-seq
MIRT1261970	hsa-miR-3591-3p	CLIP-seq
MIRT1261971	hsa-miR-3611	CLIP-seq
MIRT1261972	hsa-miR-3612	CLIP-seq
MIRT1261973	hsa-miR-3613-3p	CLIP-seq
MIRT1261974	hsa-miR-3619-5p	CLIP-seq
MIRT1261975	hsa-miR-3622b-5p	CLIP-seq
MIRT1261976	hsa-miR-362-5p	CLIP-seq
MIRT1261977	hsa-miR-363	CLIP-seq
MIRT1261978	hsa-miR-3646	CLIP-seq
MIRT1261979	hsa-miR-3666	CLIP-seq
MIRT1261980	hsa-miR-367	CLIP-seq
MIRT1261981	hsa-miR-3672	CLIP-seq
MIRT1261982	hsa-miR-3674	CLIP-seq
MIRT1261983	hsa-miR-3685	CLIP-seq
MIRT1261984	hsa-miR-3691-3p	CLIP-seq
MIRT1261985	hsa-miR-376a	CLIP-seq
MIRT1261986	hsa-miR-376b	CLIP-seq
MIRT1261987	hsa-miR-3919	CLIP-seq
MIRT1261988	hsa-miR-410	CLIP-seq
MIRT1261989	hsa-miR-4266	CLIP-seq
MIRT1261990	hsa-miR-4282	CLIP-seq
MIRT1261991	hsa-miR-4295	CLIP-seq
MIRT1261992	hsa-miR-4326	CLIP-seq
MIRT1261993	hsa-miR-4427	CLIP-seq
MIRT1261994	hsa-miR-4428	CLIP-seq
MIRT1261995	hsa-miR-4429	CLIP-seq
MIRT1261996	hsa-miR-4477a	CLIP-seq
MIRT1261997	hsa-miR-4501	CLIP-seq
MIRT1261998	hsa-miR-4521	CLIP-seq
MIRT1261999	hsa-miR-454	CLIP-seq
MIRT1262000	hsa-miR-4671-3p	CLIP-seq
MIRT1262001	hsa-miR-4680-3p	CLIP-seq
MIRT1262002	hsa-miR-4694-3p	CLIP-seq
MIRT1262003	hsa-miR-4694-5p	CLIP-seq
MIRT1262004	hsa-miR-4695-5p	CLIP-seq
MIRT1262005	hsa-miR-4709-3p	CLIP-seq
MIRT1262006	hsa-miR-4726-3p	CLIP-seq
MIRT1262007	hsa-miR-4738-3p	CLIP-seq
MIRT1262008	hsa-miR-4756-3p	CLIP-seq
MIRT1262009	hsa-miR-4764-5p	CLIP-seq
MIRT1262010	hsa-miR-4768-3p	CLIP-seq
MIRT1262011	hsa-miR-4775	CLIP-seq
MIRT1262012	hsa-miR-4779	CLIP-seq
MIRT1262013	hsa-miR-4793-5p	CLIP-seq
MIRT1262014	hsa-miR-4803	CLIP-seq
MIRT1262015	hsa-miR-494	CLIP-seq
MIRT1262016	hsa-miR-500b	CLIP-seq
MIRT1262017	hsa-miR-501-5p	CLIP-seq
MIRT1262018	hsa-miR-513a-5p	CLIP-seq
MIRT1262019	hsa-miR-548ae	CLIP-seq
MIRT1262020	hsa-miR-548ag	CLIP-seq
MIRT1262021	hsa-miR-548ai	CLIP-seq
MIRT1262022	hsa-miR-548aj	CLIP-seq
MIRT1262023	hsa-miR-548am	CLIP-seq
MIRT1262024	hsa-miR-548c-3p	CLIP-seq
MIRT1262025	hsa-miR-548x	CLIP-seq
MIRT1262026	hsa-miR-569	CLIP-seq
MIRT1262027	hsa-miR-579	CLIP-seq
MIRT1262028	hsa-miR-581	CLIP-seq
MIRT1262029	hsa-miR-589	CLIP-seq
MIRT1262030	hsa-miR-599	CLIP-seq
MIRT1262031	hsa-miR-606	CLIP-seq
MIRT1262032	hsa-miR-616	CLIP-seq
MIRT1262033	hsa-miR-642b	CLIP-seq
MIRT1262034	hsa-miR-650	CLIP-seq
MIRT1262035	hsa-miR-670	CLIP-seq
MIRT1262036	hsa-miR-758	CLIP-seq
MIRT1262037	hsa-miR-761	CLIP-seq
MIRT1262038	hsa-miR-92a	CLIP-seq
MIRT1262039	hsa-miR-92b	CLIP-seq
MIRT1262040	hsa-miR-944	CLIP-seq
MIRT2077186	hsa-miR-1246	CLIP-seq
MIRT2077187	hsa-miR-1290	CLIP-seq
MIRT1261938	hsa-miR-129-5p	CLIP-seq
MIRT2077188	hsa-miR-1299	CLIP-seq
MIRT739557	hsa-miR-203	CLIP-seq
MIRT1261947	hsa-miR-214	CLIP-seq
MIRT1261958	hsa-miR-3164	CLIP-seq
MIRT2077189	hsa-miR-3167	CLIP-seq
MIRT1261974	hsa-miR-3619-5p	CLIP-seq
MIRT1261975	hsa-miR-3622b-5p	CLIP-seq
MIRT2077190	hsa-miR-375	CLIP-seq
MIRT2077191	hsa-miR-3977	CLIP-seq
MIRT2077192	hsa-miR-4291	CLIP-seq
MIRT2077193	hsa-miR-4307	CLIP-seq
MIRT1261992	hsa-miR-4326	CLIP-seq
MIRT2077194	hsa-miR-4503	CLIP-seq
MIRT2077195	hsa-miR-4691-5p	CLIP-seq
MIRT2077196	hsa-miR-4720-5p	CLIP-seq
MIRT1262011	hsa-miR-4775	CLIP-seq
MIRT2077197	hsa-miR-4799-3p	CLIP-seq
MIRT2077198	hsa-miR-548aa	CLIP-seq
MIRT2077199	hsa-miR-548ac	CLIP-seq
MIRT1262019	hsa-miR-548ae	CLIP-seq
MIRT1262022	hsa-miR-548aj	CLIP-seq
MIRT1262023	hsa-miR-548am	CLIP-seq
MIRT2077200	hsa-miR-548d-3p	CLIP-seq
MIRT1262025	hsa-miR-548x	CLIP-seq
MIRT2077201	hsa-miR-548z	CLIP-seq
MIRT2077202	hsa-miR-561	CLIP-seq
MIRT2077203	hsa-miR-582-3p	CLIP-seq
MIRT2077204	hsa-miR-607	CLIP-seq
MIRT1262037	hsa-miR-761	CLIP-seq
MIRT2077205	hsa-miR-876-5p	CLIP-seq
MIRT2077206	hsa-miR-922	CLIP-seq
MIRT2303658	hsa-let-7a	CLIP-seq
MIRT2303659	hsa-let-7b	CLIP-seq
MIRT2303660	hsa-let-7c	CLIP-seq
MIRT2303661	hsa-let-7d	CLIP-seq
MIRT2303662	hsa-let-7e	CLIP-seq
MIRT2303663	hsa-let-7f	CLIP-seq
MIRT2303664	hsa-let-7g	CLIP-seq
MIRT2303665	hsa-let-7i	CLIP-seq
MIRT2303666	hsa-miR-106a	CLIP-seq
MIRT2303667	hsa-miR-106b	CLIP-seq
MIRT1261932	hsa-miR-1265	CLIP-seq
MIRT2303668	hsa-miR-1284	CLIP-seq
MIRT1261936	hsa-miR-1286	CLIP-seq
MIRT1261937	hsa-miR-1288	CLIP-seq
MIRT2303669	hsa-miR-1294	CLIP-seq
MIRT1261939	hsa-miR-130a	CLIP-seq
MIRT1261940	hsa-miR-130b	CLIP-seq
MIRT2303670	hsa-miR-141	CLIP-seq
MIRT2303671	hsa-miR-142-5p	CLIP-seq
MIRT2303672	hsa-miR-154	CLIP-seq
MIRT2303673	hsa-miR-17	CLIP-seq
MIRT2303674	hsa-miR-181a	CLIP-seq
MIRT2303675	hsa-miR-181b	CLIP-seq
MIRT2303676	hsa-miR-181c	CLIP-seq
MIRT2303677	hsa-miR-181d	CLIP-seq
MIRT2303678	hsa-miR-200a	CLIP-seq
MIRT2303679	hsa-miR-202	CLIP-seq
MIRT2303680	hsa-miR-20a	CLIP-seq
MIRT2303681	hsa-miR-20b	CLIP-seq
MIRT1261947	hsa-miR-214	CLIP-seq
MIRT1261950	hsa-miR-2392	CLIP-seq
MIRT2303682	hsa-miR-23a	CLIP-seq
MIRT2303683	hsa-miR-23b	CLIP-seq
MIRT2303684	hsa-miR-23c	CLIP-seq
MIRT1261951	hsa-miR-25	CLIP-seq
MIRT2303685	hsa-miR-300	CLIP-seq
MIRT1261954	hsa-miR-301a	CLIP-seq
MIRT1261955	hsa-miR-301b	CLIP-seq
MIRT2303686	hsa-miR-302a	CLIP-seq
MIRT2303687	hsa-miR-302b	CLIP-seq
MIRT2303688	hsa-miR-302c	CLIP-seq
MIRT2303689	hsa-miR-302d	CLIP-seq
MIRT2303690	hsa-miR-302e	CLIP-seq
MIRT2303691	hsa-miR-31	CLIP-seq
MIRT2303692	hsa-miR-3143	CLIP-seq
MIRT2303693	hsa-miR-3145-3p	CLIP-seq
MIRT2303694	hsa-miR-3163	CLIP-seq
MIRT1261958	hsa-miR-3164	CLIP-seq
MIRT1261959	hsa-miR-3169	CLIP-seq
MIRT2303695	hsa-miR-3194-5p	CLIP-seq
MIRT1261961	hsa-miR-32	CLIP-seq
MIRT1261962	hsa-miR-320a	CLIP-seq
MIRT1261963	hsa-miR-320b	CLIP-seq
MIRT1261964	hsa-miR-320c	CLIP-seq
MIRT1261965	hsa-miR-320d	CLIP-seq
MIRT2303696	hsa-miR-340	CLIP-seq
MIRT1261969	hsa-miR-34c-3p	CLIP-seq
MIRT1261974	hsa-miR-3619-5p	CLIP-seq
MIRT1261975	hsa-miR-3622b-5p	CLIP-seq
MIRT1261977	hsa-miR-363	CLIP-seq
MIRT1261979	hsa-miR-3666	CLIP-seq
MIRT1261980	hsa-miR-367	CLIP-seq
MIRT1261984	hsa-miR-3691-3p	CLIP-seq
MIRT2303697	hsa-miR-372	CLIP-seq
MIRT2303698	hsa-miR-373	CLIP-seq
MIRT2077190	hsa-miR-375	CLIP-seq
MIRT1261985	hsa-miR-376a	CLIP-seq
MIRT1261986	hsa-miR-376b	CLIP-seq
MIRT2303699	hsa-miR-381	CLIP-seq
MIRT2303700	hsa-miR-3945	CLIP-seq
MIRT2303701	hsa-miR-3973	CLIP-seq
MIRT2303702	hsa-miR-4262	CLIP-seq
MIRT2303703	hsa-miR-4276	CLIP-seq
MIRT1261990	hsa-miR-4282	CLIP-seq
MIRT1261991	hsa-miR-4295	CLIP-seq
MIRT2303704	hsa-miR-4311	CLIP-seq
MIRT2303705	hsa-miR-4316	CLIP-seq
MIRT2303706	hsa-miR-4420	CLIP-seq
MIRT1261995	hsa-miR-4429	CLIP-seq
MIRT2303707	hsa-miR-4458	CLIP-seq
MIRT2303708	hsa-miR-4464	CLIP-seq
MIRT2303709	hsa-miR-4495	CLIP-seq
MIRT2303710	hsa-miR-4500	CLIP-seq
MIRT2303711	hsa-miR-452	CLIP-seq
MIRT1261999	hsa-miR-454	CLIP-seq
MIRT2303712	hsa-miR-4642	CLIP-seq
MIRT2303713	hsa-miR-4666-3p	CLIP-seq
MIRT1262000	hsa-miR-4671-3p	CLIP-seq
MIRT2303714	hsa-miR-4676-3p	CLIP-seq
MIRT2303715	hsa-miR-4677-3p	CLIP-seq
MIRT2303716	hsa-miR-4677-5p	CLIP-seq
MIRT2303717	hsa-miR-4679	CLIP-seq
MIRT2303718	hsa-miR-4693-5p	CLIP-seq
MIRT2303719	hsa-miR-4704-3p	CLIP-seq
MIRT2303720	hsa-miR-4705	CLIP-seq
MIRT2077196	hsa-miR-4720-5p	CLIP-seq
MIRT1262007	hsa-miR-4738-3p	CLIP-seq
MIRT2303721	hsa-miR-4748	CLIP-seq
MIRT2303722	hsa-miR-4773	CLIP-seq
MIRT2303723	hsa-miR-4795-3p	CLIP-seq
MIRT2077197	hsa-miR-4799-3p	CLIP-seq
MIRT2303724	hsa-miR-512-3p	CLIP-seq
MIRT2303725	hsa-miR-519d	CLIP-seq
MIRT2303726	hsa-miR-520a-3p	CLIP-seq
MIRT2303727	hsa-miR-520b	CLIP-seq
MIRT2303728	hsa-miR-520c-3p	CLIP-seq
MIRT2303729	hsa-miR-520d-3p	CLIP-seq
MIRT2303730	hsa-miR-520e	CLIP-seq
MIRT2303731	hsa-miR-520g	CLIP-seq
MIRT2303732	hsa-miR-520h	CLIP-seq
MIRT1262024	hsa-miR-548c-3p	CLIP-seq
MIRT2303733	hsa-miR-548m	CLIP-seq
MIRT2303734	hsa-miR-633	CLIP-seq
MIRT2303735	hsa-miR-759	CLIP-seq
MIRT1262037	hsa-miR-761	CLIP-seq
MIRT1262038	hsa-miR-92a	CLIP-seq
MIRT1262039	hsa-miR-92b	CLIP-seq
MIRT2303736	hsa-miR-93	CLIP-seq
MIRT2303737	hsa-miR-98	CLIP-seq
MIRT2077188	hsa-miR-1299	CLIP-seq
MIRT2392964	hsa-miR-147	CLIP-seq
MIRT2392965	hsa-miR-4289	CLIP-seq
MIRT2392966	hsa-miR-4470	CLIP-seq
MIRT2392967	hsa-miR-4749-3p	CLIP-seq
MIRT2392968	hsa-miR-875-3p	CLIP-seq
MIRT2303722	hsa-miR-4773	CLIP-seq
MIRT1262019	hsa-miR-548ae	CLIP-seq
MIRT1262022	hsa-miR-548aj	CLIP-seq
MIRT1262023	hsa-miR-548am	CLIP-seq
MIRT1262025	hsa-miR-548x	CLIP-seq
MIRT2303674	hsa-miR-181a	CLIP-seq
MIRT2303675	hsa-miR-181b	CLIP-seq
MIRT2303676	hsa-miR-181c	CLIP-seq
MIRT2303677	hsa-miR-181d	CLIP-seq
MIRT2465908	hsa-miR-3938	CLIP-seq
MIRT2303702	hsa-miR-4262	CLIP-seq
MIRT2303658	hsa-let-7a	CLIP-seq
MIRT2303659	hsa-let-7b	CLIP-seq
MIRT2303660	hsa-let-7c	CLIP-seq
MIRT2303661	hsa-let-7d	CLIP-seq
MIRT2303662	hsa-let-7e	CLIP-seq
MIRT2303663	hsa-let-7f	CLIP-seq
MIRT2303664	hsa-let-7g	CLIP-seq
MIRT2303665	hsa-let-7i	CLIP-seq
MIRT1261931	hsa-miR-1208	CLIP-seq
MIRT2077186	hsa-miR-1246	CLIP-seq
MIRT2600382	hsa-miR-1255a	CLIP-seq
MIRT2600383	hsa-miR-1255b	CLIP-seq
MIRT2600384	hsa-miR-1256	CLIP-seq
MIRT1261933	hsa-miR-1267	CLIP-seq
MIRT2303669	hsa-miR-1294	CLIP-seq
MIRT1261942	hsa-miR-137	CLIP-seq
MIRT2600385	hsa-miR-139-5p	CLIP-seq
MIRT2303672	hsa-miR-154	CLIP-seq
MIRT2600386	hsa-miR-1913	CLIP-seq
MIRT1261945	hsa-miR-1915	CLIP-seq
MIRT2600387	hsa-miR-197	CLIP-seq
MIRT2303679	hsa-miR-202	CLIP-seq
MIRT739557	hsa-miR-203	CLIP-seq
MIRT1261948	hsa-miR-216b	CLIP-seq
MIRT1261951	hsa-miR-25	CLIP-seq
MIRT2600388	hsa-miR-3065-5p	CLIP-seq
MIRT2600389	hsa-miR-30a	CLIP-seq
MIRT2600390	hsa-miR-30b	CLIP-seq
MIRT2600391	hsa-miR-30c	CLIP-seq
MIRT2600392	hsa-miR-30d	CLIP-seq
MIRT2600393	hsa-miR-30e	CLIP-seq
MIRT2600394	hsa-miR-3133	CLIP-seq
MIRT2303692	hsa-miR-3143	CLIP-seq
MIRT2600395	hsa-miR-3148	CLIP-seq
MIRT2600396	hsa-miR-3155	CLIP-seq
MIRT2600397	hsa-miR-3155b	CLIP-seq
MIRT1261958	hsa-miR-3164	CLIP-seq
MIRT2600398	hsa-miR-3185	CLIP-seq
MIRT2600399	hsa-miR-3187-3p	CLIP-seq
MIRT2600400	hsa-miR-3199	CLIP-seq
MIRT1261961	hsa-miR-32	CLIP-seq
MIRT2600401	hsa-miR-324-3p	CLIP-seq
MIRT1261968	hsa-miR-335	CLIP-seq
MIRT2600402	hsa-miR-33a	CLIP-seq
MIRT2600403	hsa-miR-33b	CLIP-seq
MIRT2600404	hsa-miR-34a	CLIP-seq
MIRT1261969	hsa-miR-34c-3p	CLIP-seq
MIRT2600405	hsa-miR-34c-5p	CLIP-seq
MIRT1261973	hsa-miR-3613-3p	CLIP-seq
MIRT2600406	hsa-miR-361-5p	CLIP-seq
MIRT1261975	hsa-miR-3622b-5p	CLIP-seq
MIRT1261977	hsa-miR-363	CLIP-seq
MIRT1261978	hsa-miR-3646	CLIP-seq
MIRT2600407	hsa-miR-3663-5p	CLIP-seq
MIRT1261980	hsa-miR-367	CLIP-seq
MIRT2600408	hsa-miR-3688-3p	CLIP-seq
MIRT2600409	hsa-miR-374c	CLIP-seq
MIRT2600410	hsa-miR-377	CLIP-seq
MIRT2077191	hsa-miR-3977	CLIP-seq
MIRT2600411	hsa-miR-411	CLIP-seq
MIRT2600412	hsa-miR-4293	CLIP-seq
MIRT2600413	hsa-miR-4305	CLIP-seq
MIRT2303705	hsa-miR-4316	CLIP-seq
MIRT2600414	hsa-miR-4320	CLIP-seq
MIRT2600415	hsa-miR-4327	CLIP-seq
MIRT2600416	hsa-miR-4328	CLIP-seq
MIRT2600417	hsa-miR-4435	CLIP-seq
MIRT2600418	hsa-miR-4438	CLIP-seq
MIRT2600419	hsa-miR-4453	CLIP-seq
MIRT2303707	hsa-miR-4458	CLIP-seq
MIRT2600420	hsa-miR-4463	CLIP-seq
MIRT2600421	hsa-miR-4474-5p	CLIP-seq
MIRT2600422	hsa-miR-4475	CLIP-seq
MIRT2600423	hsa-miR-4477b	CLIP-seq
MIRT2600424	hsa-miR-4494	CLIP-seq
MIRT2600425	hsa-miR-449a	CLIP-seq
MIRT2600426	hsa-miR-449b	CLIP-seq
MIRT2303710	hsa-miR-4500	CLIP-seq
MIRT2077194	hsa-miR-4503	CLIP-seq
MIRT2600427	hsa-miR-4538	CLIP-seq
MIRT2600428	hsa-miR-4641	CLIP-seq
MIRT2600429	hsa-miR-4650-5p	CLIP-seq
MIRT2600430	hsa-miR-4668-3p	CLIP-seq
MIRT2303715	hsa-miR-4677-3p	CLIP-seq
MIRT2303717	hsa-miR-4679	CLIP-seq
MIRT2600431	hsa-miR-4684-3p	CLIP-seq
MIRT2600432	hsa-miR-4686	CLIP-seq
MIRT2600433	hsa-miR-4687-3p	CLIP-seq
MIRT2600434	hsa-miR-4698	CLIP-seq
MIRT2600435	hsa-miR-4701-5p	CLIP-seq
MIRT2600436	hsa-miR-4708-3p	CLIP-seq
MIRT2600437	hsa-miR-4716-5p	CLIP-seq
MIRT2077196	hsa-miR-4720-5p	CLIP-seq
MIRT1262006	hsa-miR-4726-3p	CLIP-seq
MIRT1262007	hsa-miR-4738-3p	CLIP-seq
MIRT1262010	hsa-miR-4768-3p	CLIP-seq
MIRT1262011	hsa-miR-4775	CLIP-seq
MIRT2600438	hsa-miR-4777-5p	CLIP-seq
MIRT2600439	hsa-miR-4781-3p	CLIP-seq
MIRT2303723	hsa-miR-4795-3p	CLIP-seq
MIRT2077197	hsa-miR-4799-3p	CLIP-seq
MIRT2600440	hsa-miR-484	CLIP-seq
MIRT2600441	hsa-miR-5095	CLIP-seq
MIRT2600442	hsa-miR-5096	CLIP-seq
MIRT2600443	hsa-miR-518a-5p	CLIP-seq
MIRT2600444	hsa-miR-518d-5p	CLIP-seq
MIRT2600445	hsa-miR-519b-5p	CLIP-seq
MIRT2600446	hsa-miR-519c-5p	CLIP-seq
MIRT2600447	hsa-miR-520c-5p	CLIP-seq
MIRT2600448	hsa-miR-526a	CLIP-seq
MIRT2600449	hsa-miR-527	CLIP-seq
MIRT2600450	hsa-miR-543	CLIP-seq
MIRT1262019	hsa-miR-548ae	CLIP-seq
MIRT1262022	hsa-miR-548aj	CLIP-seq
MIRT1262023	hsa-miR-548am	CLIP-seq
MIRT2600451	hsa-miR-548s	CLIP-seq
MIRT1262025	hsa-miR-548x	CLIP-seq
MIRT1262027	hsa-miR-579	CLIP-seq
MIRT2600452	hsa-miR-588	CLIP-seq
MIRT2600453	hsa-miR-590-3p	CLIP-seq
MIRT2600454	hsa-miR-618	CLIP-seq
MIRT2600455	hsa-miR-622	CLIP-seq
MIRT1262033	hsa-miR-642b	CLIP-seq
MIRT2600456	hsa-miR-655	CLIP-seq
MIRT1262038	hsa-miR-92a	CLIP-seq
MIRT1262039	hsa-miR-92b	CLIP-seq
MIRT2303737	hsa-miR-98	CLIP-seq
MIRT1261931	hsa-miR-1208	CLIP-seq
MIRT2600384	hsa-miR-1256	CLIP-seq
MIRT1261933	hsa-miR-1267	CLIP-seq
MIRT2600385	hsa-miR-139-5p	CLIP-seq
MIRT1261945	hsa-miR-1915	CLIP-seq
MIRT2600387	hsa-miR-197	CLIP-seq
MIRT739557	hsa-miR-203	CLIP-seq
MIRT1261948	hsa-miR-216b	CLIP-seq
MIRT2600389	hsa-miR-30a	CLIP-seq
MIRT2600390	hsa-miR-30b	CLIP-seq
MIRT2600391	hsa-miR-30c	CLIP-seq
MIRT2600392	hsa-miR-30d	CLIP-seq
MIRT2600393	hsa-miR-30e	CLIP-seq
MIRT2303692	hsa-miR-3143	CLIP-seq
MIRT2600399	hsa-miR-3187-3p	CLIP-seq
MIRT2600400	hsa-miR-3199	CLIP-seq
MIRT1261968	hsa-miR-335	CLIP-seq
MIRT2600404	hsa-miR-34a	CLIP-seq
MIRT1261969	hsa-miR-34c-3p	CLIP-seq
MIRT2600405	hsa-miR-34c-5p	CLIP-seq
MIRT1261975	hsa-miR-3622b-5p	CLIP-seq
MIRT2600407	hsa-miR-3663-5p	CLIP-seq
MIRT2600409	hsa-miR-374c	CLIP-seq
MIRT2600411	hsa-miR-411	CLIP-seq
MIRT2600412	hsa-miR-4293	CLIP-seq
MIRT2600413	hsa-miR-4305	CLIP-seq
MIRT2600414	hsa-miR-4320	CLIP-seq
MIRT2600415	hsa-miR-4327	CLIP-seq
MIRT2600417	hsa-miR-4435	CLIP-seq
MIRT2600418	hsa-miR-4438	CLIP-seq
MIRT2600419	hsa-miR-4453	CLIP-seq
MIRT2600420	hsa-miR-4463	CLIP-seq
MIRT2600422	hsa-miR-4475	CLIP-seq
MIRT2600423	hsa-miR-4477b	CLIP-seq
MIRT2600424	hsa-miR-4494	CLIP-seq
MIRT2600425	hsa-miR-449a	CLIP-seq
MIRT2600426	hsa-miR-449b	CLIP-seq
MIRT2600427	hsa-miR-4538	CLIP-seq
MIRT2600429	hsa-miR-4650-5p	CLIP-seq
MIRT2303717	hsa-miR-4679	CLIP-seq
MIRT2600435	hsa-miR-4701-5p	CLIP-seq
MIRT2600436	hsa-miR-4708-3p	CLIP-seq
MIRT2600437	hsa-miR-4716-5p	CLIP-seq
MIRT2077196	hsa-miR-4720-5p	CLIP-seq
MIRT1262006	hsa-miR-4726-3p	CLIP-seq
MIRT1262007	hsa-miR-4738-3p	CLIP-seq
MIRT1262011	hsa-miR-4775	CLIP-seq
MIRT2600438	hsa-miR-4777-5p	CLIP-seq
MIRT2600439	hsa-miR-4781-3p	CLIP-seq
MIRT2303723	hsa-miR-4795-3p	CLIP-seq
MIRT2077197	hsa-miR-4799-3p	CLIP-seq
MIRT2600441	hsa-miR-5095	CLIP-seq
MIRT2600442	hsa-miR-5096	CLIP-seq
MIRT2600443	hsa-miR-518a-5p	CLIP-seq
MIRT2600444	hsa-miR-518d-5p	CLIP-seq
MIRT2600445	hsa-miR-519b-5p	CLIP-seq
MIRT2600446	hsa-miR-519c-5p	CLIP-seq
MIRT2600447	hsa-miR-520c-5p	CLIP-seq
MIRT2600448	hsa-miR-526a	CLIP-seq
MIRT2600449	hsa-miR-527	CLIP-seq
MIRT2600450	hsa-miR-543	CLIP-seq
MIRT1262024	hsa-miR-548c-3p	CLIP-seq
MIRT2688587	hsa-miR-548g	CLIP-seq
MIRT2303733	hsa-miR-548m	CLIP-seq
MIRT2600451	hsa-miR-548s	CLIP-seq
MIRT1262027	hsa-miR-579	CLIP-seq
MIRT2600452	hsa-miR-588	CLIP-seq
MIRT2600453	hsa-miR-590-3p	CLIP-seq
MIRT2600454	hsa-miR-618	CLIP-seq
MIRT2600455	hsa-miR-622	CLIP-seq
MIRT1262033	hsa-miR-642b	CLIP-seq
MIRT2600456	hsa-miR-655	CLIP-seq

Show/Hide all(65)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003682	Function	Chromatin binding	ISS
GO:0004672	Function	Protein kinase activity	TAS	7959015
GO:0004674	Function	Protein serine/threonine kinase activity	IBA	21873635
GO:0004674	Function	Protein serine/threonine kinase activity	ISS
GO:0004679	Function	AMP-activated protein kinase activity	IDA	18439900
GO:0004679	Function	AMP-activated protein kinase activity	ISS
GO:0004712	Function	Protein serine/threonine/tyrosine kinase activity	IDA	22797923
GO:0005515	Function	Protein binding	IPI	18439900, 19274086, 20562859, 20801214, 21072212, 21516116, 24722188, 25241761, 25416956, 28514442, 28561066, 29892012, 30886144, 31515488, 32296183, 32814053
GO:0005524	Function	ATP binding	IEA
GO:0005634	Component	Nucleus	IBA	21873635
GO:0005634	Component	Nucleus	TAS	21768291
GO:0005654	Component	Nucleoplasm	TAS
GO:0005737	Component	Cytoplasm	IBA	21873635
GO:0005794	Component	Golgi apparatus	IDA
GO:0005829	Component	Cytosol	TAS
GO:0006468	Process	Protein phosphorylation	IBA	21873635
GO:0006633	Process	Fatty acid biosynthetic process	IEA
GO:0006695	Process	Cholesterol biosynthetic process	IEA
GO:0006853	Process	Carnitine shuttle	TAS
GO:0007050	Process	Cell cycle arrest	TAS
GO:0007165	Process	Signal transduction	TAS	7959015
GO:0008610	Process	Lipid biosynthetic process	ISS
GO:0010494	Component	Cytoplasmic stress granule	ISS
GO:0010508	Process	Positive regulation of autophagy	ISS
GO:0010629	Process	Negative regulation of gene expression	ISS
GO:0014850	Process	Response to muscle activity	IEA
GO:0016055	Process	Wnt signaling pathway	IEA
GO:0016236	Process	Macroautophagy	TAS
GO:0016239	Process	Positive regulation of macroautophagy	TAS	25126726
GO:0016241	Process	Regulation of macroautophagy	ISS
GO:0016241	Process	Regulation of macroautophagy	TAS
GO:0016607	Component	Nuclear speck	IDA
GO:0030424	Component	Axon	ISS
GO:0030425	Component	Dendrite	ISS
GO:0031669	Process	Cellular response to nutrient levels	ISS
GO:0032007	Process	Negative regulation of TOR signaling	ISS
GO:0034599	Process	Cellular response to oxidative stress	ISS
GO:0035174	Function	Histone serine kinase activity	ISS
GO:0035404	Process	Histone-serine phosphorylation	IEA
GO:0035556	Process	Intracellular signal transduction	IBA	21873635
GO:0035690	Process	Cellular response to drug	IEA
GO:0042149	Process	Cellular response to glucose starvation	ISS
GO:0042304	Process	Regulation of fatty acid biosynthetic process	TAS
GO:0042593	Process	Glucose homeostasis	ISS
GO:0042752	Process	Regulation of circadian rhythm	ISS
GO:0043025	Component	Neuronal cell body	ISS
GO:0043066	Process	Negative regulation of apoptotic process	ISS
GO:0045821	Process	Positive regulation of glycolytic process	ISS
GO:0046872	Function	Metal ion binding	IEA
GO:0047322	Function	[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity	IEA
GO:0048511	Process	Rhythmic process	IEA
GO:0050405	Function	[acetyl-CoA carboxylase] kinase activity	IEA
GO:0055089	Process	Fatty acid homeostasis	ISS
GO:0062028	Process	Regulation of stress granule assembly	IEA
GO:0070507	Process	Regulation of microtubule cytoskeleton organization	ISS
GO:0071277	Process	Cellular response to calcium ion	ISS
GO:0071333	Process	Cellular response to glucose stimulus	ISS
GO:0071380	Process	Cellular response to prostaglandin E stimulus	IEA
GO:0097009	Process	Energy homeostasis	ISS
GO:0106310	Function	Protein serine kinase activity	IEA
GO:0106311	Function	Protein threonine kinase activity	IEA
GO:1901796	Process	Regulation of signal transduction by p53 class mediator	TAS
GO:1903829	Process	Positive regulation of cellular protein localization	ISS
GO:1904428	Process	Negative regulation of tubulin deacetylation	ISS
GO:2000758	Process	Positive regulation of peptidyl-lysine acetylation	ISS

MIM	HGNC	e!Ensembl
600497	9377	ENSG00000162409

Protein

UniProt ID

P54646

Protein name

5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31)

Protein function

Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism (PubMed:17307971, PubMed:17712357). In response to reduction of intracellular ATP levels, AM

PDB

2H6D , 2LTU , 2YZA , 3AQV , 4CFE , 4CFF , 4ZHX , 5EZV , 5ISO , 6B1U , 6B2E , 6BX6 , 7MYJ , 8BIK

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00069	Pkinase	16 → 268	Protein kinase domain	Domain
PF16579	AdenylateSensor	401 → 495	Adenylate sensor of SNF1-like protein kinase	Domain

Sequence

MAEKQKHDGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGK
IKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLF
QQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYA
APEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRS
VATLLMHMLQVDPLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKF
ECTESEVMNSLYSGDPQDQLAVAYHLIIDNRRIMNQASEFYLASSPPSGSFMDDSAMHIP
PGLKPHPERMPPLIADSPKARCPLDALNTTKPKSLAVKKAKWHLGIRSQSKPYDIMAEVY
RAMKQLDFEWKVVNAYHLRVRRKNPVTGNYVKMSLQLYLVDNRSYLLDFKSIDDEVVEQR
SGSSTPQRSCSAAGLHRPRSSFDSTTAESHSLSGSLTGSLTGSTLSSVSPRLGSHTMDFF
EMCASLITTLAR

Sequence length

552

Interactions

View interactions

PRKAA2 (protein kinase AMP-activated catalytic subunit alpha 2)