Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs Other IDs Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	5529
Gene name Gene Name - the full gene name approved by the HGNC.	Protein phosphatase 2 regulatory subunit B'epsilon
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	PPP2R5E
Synonyms (NCBI Gene) Gene synonyms aliases	B56E, B56epsilon
Chromosome Chromosome number	14
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	14q23.2
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a co

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miRTarBase ID	miRNA	Experiments	Reference
MIRT006743	hsa-miR-19b-3p	Luciferase reporter assay	20190740
MIRT006743	hsa-miR-19b-3p	Luciferase reporter assay	20190740
MIRT051983	hsa-let-7b-5p	CLASH	23622248
MIRT051753	hsa-let-7c-5p	CLASH	23622248
MIRT045699	hsa-miR-125a-5p	CLASH	23622248
MIRT044037	hsa-miR-365a-3p	CLASH	23622248
MIRT054034	hsa-miR-23a-3p	GFP reporter assay, qRT-PCR, Western blot	24997345
MIRT054034	hsa-miR-23a-3p	GFP reporter assay, qRT-PCR, Western blot	24997345
MIRT710559	hsa-miR-2355-5p	HITS-CLIP	19536157
MIRT710558	hsa-miR-510-3p	HITS-CLIP	19536157
MIRT542106	hsa-miR-4662a-3p	HITS-CLIP	21572407
MIRT542104	hsa-miR-3163	HITS-CLIP	21572407
MIRT542105	hsa-miR-410-3p	HITS-CLIP	21572407
MIRT542102	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT542103	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT542101	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT542106	hsa-miR-4662a-3p	HITS-CLIP	21572407
MIRT542104	hsa-miR-3163	HITS-CLIP	21572407
MIRT542105	hsa-miR-410-3p	HITS-CLIP	21572407
MIRT542102	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT542103	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT542101	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT622614	hsa-miR-548ae-3p	HITS-CLIP	23824327
MIRT622613	hsa-miR-548ah-3p	HITS-CLIP	23824327
MIRT622612	hsa-miR-548aj-3p	HITS-CLIP	23824327
MIRT622611	hsa-miR-548am-3p	HITS-CLIP	23824327
MIRT622610	hsa-miR-548aq-3p	HITS-CLIP	23824327
MIRT622609	hsa-miR-548j-3p	HITS-CLIP	23824327
MIRT622608	hsa-miR-548x-3p	HITS-CLIP	23824327
MIRT622614	hsa-miR-548ae-3p	HITS-CLIP	23824327
MIRT622613	hsa-miR-548ah-3p	HITS-CLIP	23824327
MIRT622612	hsa-miR-548aj-3p	HITS-CLIP	23824327
MIRT622611	hsa-miR-548am-3p	HITS-CLIP	23824327
MIRT622610	hsa-miR-548aq-3p	HITS-CLIP	23824327
MIRT622609	hsa-miR-548j-3p	HITS-CLIP	23824327
MIRT622608	hsa-miR-548x-3p	HITS-CLIP	23824327
MIRT542106	hsa-miR-4662a-3p	PAR-CLIP	21572407
MIRT542104	hsa-miR-3163	PAR-CLIP	21572407
MIRT542105	hsa-miR-410-3p	PAR-CLIP	21572407
MIRT542102	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT542103	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT542101	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT470388	hsa-miR-19a-3p	PAR-CLIP	23592263
MIRT006743	hsa-miR-19b-3p	PAR-CLIP	23592263
MIRT470387	hsa-miR-181b-5p	PAR-CLIP	23592263
MIRT470386	hsa-miR-4262	PAR-CLIP	23592263
MIRT470385	hsa-miR-181d-5p	PAR-CLIP	23592263
MIRT470384	hsa-miR-181c-5p	PAR-CLIP	23592263
MIRT470383	hsa-miR-181a-5p	PAR-CLIP	23592263
MIRT470382	hsa-miR-4731-3p	PAR-CLIP	23592263
MIRT470381	hsa-miR-4801	PAR-CLIP	23592263
MIRT470380	hsa-miR-510-5p	PAR-CLIP	23592263
MIRT470379	hsa-miR-576-3p	PAR-CLIP	23592263
MIRT470378	hsa-miR-1265	PAR-CLIP	23592263
MIRT470377	hsa-miR-101-5p	PAR-CLIP	23592263
MIRT470376	hsa-miR-5586-5p	PAR-CLIP	23592263
MIRT470375	hsa-miR-6504-3p	PAR-CLIP	23592263
MIRT470374	hsa-miR-4272	PAR-CLIP	23592263
MIRT470373	hsa-miR-6847-5p	PAR-CLIP	23592263
MIRT470372	hsa-miR-873-5p	PAR-CLIP	23592263
MIRT470371	hsa-miR-3664-3p	PAR-CLIP	23592263
MIRT470370	hsa-miR-3605-5p	PAR-CLIP	23592263
MIRT470369	hsa-miR-548aj-5p	PAR-CLIP	23592263
MIRT470368	hsa-miR-548f-5p	PAR-CLIP	23592263
MIRT470367	hsa-miR-548g-5p	PAR-CLIP	23592263
MIRT470366	hsa-miR-548x-5p	PAR-CLIP	23592263
MIRT470365	hsa-miR-1468-3p	PAR-CLIP	23592263
MIRT470364	hsa-miR-6894-5p	PAR-CLIP	23592263
MIRT470363	hsa-miR-3138	PAR-CLIP	23592263
MIRT470362	hsa-miR-3941	PAR-CLIP	23592263
MIRT470361	hsa-miR-4672	PAR-CLIP	23592263
MIRT470360	hsa-miR-466	PAR-CLIP	23592263
MIRT470359	hsa-miR-101-3p	PAR-CLIP	23592263
MIRT470358	hsa-miR-582-5p	PAR-CLIP	23592263
MIRT470357	hsa-miR-520a-5p	PAR-CLIP	23592263
MIRT470356	hsa-miR-525-5p	PAR-CLIP	23592263
MIRT470355	hsa-miR-548aw	PAR-CLIP	23592263
MIRT470354	hsa-miR-548l	PAR-CLIP	23592263
MIRT470353	hsa-miR-4712-3p	PAR-CLIP	23592263
MIRT470352	hsa-miR-3973	PAR-CLIP	23592263
MIRT470351	hsa-miR-520g-3p	PAR-CLIP	23592263
MIRT470350	hsa-miR-520h	PAR-CLIP	23592263
MIRT470349	hsa-miR-143-3p	PAR-CLIP	23592263
MIRT470348	hsa-miR-4770	PAR-CLIP	23592263
MIRT470347	hsa-miR-6088	PAR-CLIP	23592263
MIRT470346	hsa-miR-4708-5p	PAR-CLIP	23592263
MIRT470345	hsa-miR-1273f	PAR-CLIP	23592263
MIRT470344	hsa-miR-6794-3p	PAR-CLIP	23592263
MIRT470342	hsa-miR-4452	PAR-CLIP	23592263
MIRT470343	hsa-miR-1273e	PAR-CLIP	23592263
MIRT470341	hsa-miR-1262	PAR-CLIP	23592263
MIRT470339	hsa-miR-4701-3p	PAR-CLIP	23592263
MIRT470340	hsa-miR-6736-5p	PAR-CLIP	23592263
MIRT439912	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT439912	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT006743	hsa-miR-19b-3p	Luciferase reporter assay	27720936
MIRT710559	hsa-miR-2355-5p	HITS-CLIP	19536157
MIRT710558	hsa-miR-510-3p	HITS-CLIP	19536157
MIRT542106	hsa-miR-4662a-3p	HITS-CLIP	21572407
MIRT542104	hsa-miR-3163	HITS-CLIP	21572407
MIRT542105	hsa-miR-410-3p	HITS-CLIP	21572407
MIRT542102	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT542103	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT542101	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT542106	hsa-miR-4662a-3p	HITS-CLIP	21572407
MIRT542104	hsa-miR-3163	HITS-CLIP	21572407
MIRT542105	hsa-miR-410-3p	HITS-CLIP	21572407
MIRT542102	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT542103	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT542101	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT622614	hsa-miR-548ae-3p	HITS-CLIP	23824327
MIRT622613	hsa-miR-548ah-3p	HITS-CLIP	23824327
MIRT622612	hsa-miR-548aj-3p	HITS-CLIP	23824327
MIRT622611	hsa-miR-548am-3p	HITS-CLIP	23824327
MIRT622610	hsa-miR-548aq-3p	HITS-CLIP	23824327
MIRT622609	hsa-miR-548j-3p	HITS-CLIP	23824327
MIRT622608	hsa-miR-548x-3p	HITS-CLIP	23824327
MIRT622614	hsa-miR-548ae-3p	HITS-CLIP	23824327
MIRT622613	hsa-miR-548ah-3p	HITS-CLIP	23824327
MIRT622612	hsa-miR-548aj-3p	HITS-CLIP	23824327
MIRT622611	hsa-miR-548am-3p	HITS-CLIP	23824327
MIRT622610	hsa-miR-548aq-3p	HITS-CLIP	23824327
MIRT622609	hsa-miR-548j-3p	HITS-CLIP	23824327
MIRT622608	hsa-miR-548x-3p	HITS-CLIP	23824327
MIRT542106	hsa-miR-4662a-3p	PAR-CLIP	21572407
MIRT542104	hsa-miR-3163	PAR-CLIP	21572407
MIRT542105	hsa-miR-410-3p	PAR-CLIP	21572407
MIRT542102	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT542103	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT542101	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT470388	hsa-miR-19a-3p	PAR-CLIP	23592263
MIRT006743	hsa-miR-19b-3p	PAR-CLIP	23592263
MIRT470387	hsa-miR-181b-5p	PAR-CLIP	23592263
MIRT470386	hsa-miR-4262	PAR-CLIP	23592263
MIRT470385	hsa-miR-181d-5p	PAR-CLIP	23592263
MIRT470384	hsa-miR-181c-5p	PAR-CLIP	23592263
MIRT470383	hsa-miR-181a-5p	PAR-CLIP	23592263
MIRT470382	hsa-miR-4731-3p	PAR-CLIP	23592263
MIRT470381	hsa-miR-4801	PAR-CLIP	23592263
MIRT470380	hsa-miR-510-5p	PAR-CLIP	23592263
MIRT470379	hsa-miR-576-3p	PAR-CLIP	23592263
MIRT470378	hsa-miR-1265	PAR-CLIP	23592263
MIRT470377	hsa-miR-101-5p	PAR-CLIP	23592263
MIRT470376	hsa-miR-5586-5p	PAR-CLIP	23592263
MIRT470375	hsa-miR-6504-3p	PAR-CLIP	23592263
MIRT470374	hsa-miR-4272	PAR-CLIP	23592263
MIRT470373	hsa-miR-6847-5p	PAR-CLIP	23592263
MIRT470372	hsa-miR-873-5p	PAR-CLIP	23592263
MIRT470371	hsa-miR-3664-3p	PAR-CLIP	23592263
MIRT470370	hsa-miR-3605-5p	PAR-CLIP	23592263
MIRT470369	hsa-miR-548aj-5p	PAR-CLIP	23592263
MIRT470368	hsa-miR-548f-5p	PAR-CLIP	23592263
MIRT470367	hsa-miR-548g-5p	PAR-CLIP	23592263
MIRT470366	hsa-miR-548x-5p	PAR-CLIP	23592263
MIRT470365	hsa-miR-1468-3p	PAR-CLIP	23592263
MIRT470364	hsa-miR-6894-5p	PAR-CLIP	23592263
MIRT470363	hsa-miR-3138	PAR-CLIP	23592263
MIRT470362	hsa-miR-3941	PAR-CLIP	23592263
MIRT470361	hsa-miR-4672	PAR-CLIP	23592263
MIRT470360	hsa-miR-466	PAR-CLIP	23592263
MIRT470359	hsa-miR-101-3p	PAR-CLIP	23592263
MIRT470358	hsa-miR-582-5p	PAR-CLIP	23592263
MIRT470357	hsa-miR-520a-5p	PAR-CLIP	23592263
MIRT470356	hsa-miR-525-5p	PAR-CLIP	23592263
MIRT470355	hsa-miR-548aw	PAR-CLIP	23592263
MIRT470354	hsa-miR-548l	PAR-CLIP	23592263
MIRT470353	hsa-miR-4712-3p	PAR-CLIP	23592263
MIRT470352	hsa-miR-3973	PAR-CLIP	23592263
MIRT470351	hsa-miR-520g-3p	PAR-CLIP	23592263
MIRT470350	hsa-miR-520h	PAR-CLIP	23592263
MIRT470349	hsa-miR-143-3p	PAR-CLIP	23592263
MIRT470348	hsa-miR-4770	PAR-CLIP	23592263
MIRT470347	hsa-miR-6088	PAR-CLIP	23592263
MIRT470346	hsa-miR-4708-5p	PAR-CLIP	23592263
MIRT470345	hsa-miR-1273f	PAR-CLIP	23592263
MIRT470344	hsa-miR-6794-3p	PAR-CLIP	23592263
MIRT470342	hsa-miR-4452	PAR-CLIP	23592263
MIRT470343	hsa-miR-1273e	PAR-CLIP	23592263
MIRT470341	hsa-miR-1262	PAR-CLIP	23592263
MIRT470339	hsa-miR-4701-3p	PAR-CLIP	23592263
MIRT470340	hsa-miR-6736-5p	PAR-CLIP	23592263
MIRT1258104	hsa-miR-1303	CLIP-seq
MIRT1258105	hsa-miR-134	CLIP-seq
MIRT1258106	hsa-miR-3118	CLIP-seq
MIRT1258107	hsa-miR-3143	CLIP-seq
MIRT1258108	hsa-miR-3164	CLIP-seq
MIRT1258109	hsa-miR-326	CLIP-seq
MIRT1258110	hsa-miR-330-5p	CLIP-seq
MIRT1258111	hsa-miR-3616-5p	CLIP-seq
MIRT1258112	hsa-miR-3647-5p	CLIP-seq
MIRT1258113	hsa-miR-3658	CLIP-seq
MIRT1258114	hsa-miR-3674	CLIP-seq
MIRT1258115	hsa-miR-3908	CLIP-seq
MIRT1258116	hsa-miR-3942-5p	CLIP-seq
MIRT1258117	hsa-miR-409-3p	CLIP-seq
MIRT1258118	hsa-miR-421	CLIP-seq
MIRT1258119	hsa-miR-4263	CLIP-seq
MIRT1258120	hsa-miR-4445	CLIP-seq
MIRT1258121	hsa-miR-4490	CLIP-seq
MIRT1258122	hsa-miR-4524	CLIP-seq
MIRT1258123	hsa-miR-4645-3p	CLIP-seq
MIRT1258124	hsa-miR-4659a-3p	CLIP-seq
MIRT1258125	hsa-miR-4659b-3p	CLIP-seq
MIRT1258126	hsa-miR-4703-5p	CLIP-seq
MIRT1258127	hsa-miR-4709-5p	CLIP-seq
MIRT1258128	hsa-miR-4766-3p	CLIP-seq
MIRT1258129	hsa-miR-4774-5p	CLIP-seq
MIRT1258130	hsa-miR-4799-5p	CLIP-seq
MIRT1258131	hsa-miR-4803	CLIP-seq
MIRT1258132	hsa-miR-495	CLIP-seq
MIRT1258133	hsa-miR-512-3p	CLIP-seq
MIRT1258134	hsa-miR-513a-3p	CLIP-seq
MIRT1258135	hsa-miR-573	CLIP-seq
MIRT1258136	hsa-miR-576-5p	CLIP-seq
MIRT1258137	hsa-miR-590-3p	CLIP-seq
MIRT1258138	hsa-miR-616	CLIP-seq
MIRT2076042	hsa-miR-1179	CLIP-seq
MIRT2076043	hsa-miR-132	CLIP-seq
MIRT1258105	hsa-miR-134	CLIP-seq
MIRT2076044	hsa-miR-146a	CLIP-seq
MIRT2076045	hsa-miR-146b-5p	CLIP-seq
MIRT2076046	hsa-miR-199a-3p	CLIP-seq
MIRT2076047	hsa-miR-199b-3p	CLIP-seq
MIRT2076048	hsa-miR-200b	CLIP-seq
MIRT2076049	hsa-miR-200c	CLIP-seq
MIRT2076050	hsa-miR-212	CLIP-seq
MIRT1258106	hsa-miR-3118	CLIP-seq
MIRT2076051	hsa-miR-3129-5p	CLIP-seq
MIRT2076052	hsa-miR-3162-3p	CLIP-seq
MIRT1258108	hsa-miR-3164	CLIP-seq
MIRT2076053	hsa-miR-3180-5p	CLIP-seq
MIRT2076054	hsa-miR-374c	CLIP-seq
MIRT1258117	hsa-miR-409-3p	CLIP-seq
MIRT2076055	hsa-miR-4289	CLIP-seq
MIRT2076056	hsa-miR-429	CLIP-seq
MIRT2076057	hsa-miR-4307	CLIP-seq
MIRT2076058	hsa-miR-4436a	CLIP-seq
MIRT2076059	hsa-miR-4477a	CLIP-seq
MIRT2076060	hsa-miR-4509	CLIP-seq
MIRT2076061	hsa-miR-455-3p	CLIP-seq
MIRT2076062	hsa-miR-4679	CLIP-seq
MIRT2076063	hsa-miR-4735-5p	CLIP-seq
MIRT2076064	hsa-miR-4764-3p	CLIP-seq
MIRT2076065	hsa-miR-4768-5p	CLIP-seq
MIRT2076066	hsa-miR-4775	CLIP-seq
MIRT2076067	hsa-miR-4795-3p	CLIP-seq
MIRT2076068	hsa-miR-510	CLIP-seq
MIRT2076069	hsa-miR-512-5p	CLIP-seq
MIRT2076070	hsa-miR-548a-3p	CLIP-seq
MIRT2076071	hsa-miR-548e	CLIP-seq
MIRT2076072	hsa-miR-548f	CLIP-seq
MIRT2076073	hsa-miR-548g	CLIP-seq
MIRT2076074	hsa-miR-583	CLIP-seq
MIRT2076075	hsa-miR-589	CLIP-seq
MIRT1258137	hsa-miR-590-3p	CLIP-seq
MIRT1258138	hsa-miR-616	CLIP-seq
MIRT2076076	hsa-miR-655	CLIP-seq
MIRT2076077	hsa-miR-936	CLIP-seq
MIRT2076078	hsa-miR-942	CLIP-seq
MIRT2302639	hsa-miR-1178	CLIP-seq
MIRT2076042	hsa-miR-1179	CLIP-seq
MIRT2076046	hsa-miR-199a-3p	CLIP-seq
MIRT2076047	hsa-miR-199b-3p	CLIP-seq
MIRT2302640	hsa-miR-2964a-5p	CLIP-seq
MIRT2076051	hsa-miR-3129-5p	CLIP-seq
MIRT1258114	hsa-miR-3674	CLIP-seq
MIRT2302641	hsa-miR-4446-5p	CLIP-seq
MIRT2076061	hsa-miR-455-3p	CLIP-seq
MIRT2076062	hsa-miR-4679	CLIP-seq
MIRT2302642	hsa-miR-4724-5p	CLIP-seq
MIRT2302643	hsa-miR-4760-3p	CLIP-seq
MIRT2302644	hsa-miR-4786-3p	CLIP-seq
MIRT2076077	hsa-miR-936	CLIP-seq
MIRT2392924	hsa-miR-494	CLIP-seq
MIRT2599306	hsa-miR-1183	CLIP-seq
MIRT2599307	hsa-miR-1287	CLIP-seq
MIRT2599308	hsa-miR-194	CLIP-seq
MIRT2599309	hsa-miR-204	CLIP-seq
MIRT2599310	hsa-miR-211	CLIP-seq
MIRT2599311	hsa-miR-221	CLIP-seq
MIRT2599312	hsa-miR-222	CLIP-seq
MIRT2599313	hsa-miR-3135b	CLIP-seq
MIRT2076052	hsa-miR-3162-3p	CLIP-seq
MIRT2599314	hsa-miR-3607-3p	CLIP-seq
MIRT2599315	hsa-miR-3938	CLIP-seq
MIRT2599316	hsa-miR-3975	CLIP-seq
MIRT2076057	hsa-miR-4307	CLIP-seq
MIRT2302641	hsa-miR-4446-5p	CLIP-seq
MIRT2076060	hsa-miR-4509	CLIP-seq
MIRT2076063	hsa-miR-4735-5p	CLIP-seq
MIRT2599317	hsa-miR-4755-5p	CLIP-seq
MIRT2076064	hsa-miR-4764-3p	CLIP-seq
MIRT2076065	hsa-miR-4768-5p	CLIP-seq
MIRT2076066	hsa-miR-4775	CLIP-seq
MIRT2076070	hsa-miR-548a-3p	CLIP-seq
MIRT2076071	hsa-miR-548e	CLIP-seq
MIRT2076072	hsa-miR-548f	CLIP-seq
MIRT2599318	hsa-miR-561	CLIP-seq
MIRT1258137	hsa-miR-590-3p	CLIP-seq
MIRT2599319	hsa-miR-623	CLIP-seq
MIRT2076078	hsa-miR-942	CLIP-seq
MIRT2599308	hsa-miR-194	CLIP-seq
MIRT2599309	hsa-miR-204	CLIP-seq
MIRT2599310	hsa-miR-211	CLIP-seq
MIRT2599311	hsa-miR-221	CLIP-seq
MIRT2599312	hsa-miR-222	CLIP-seq
MIRT2076052	hsa-miR-3162-3p	CLIP-seq
MIRT2599315	hsa-miR-3938	CLIP-seq
MIRT2599316	hsa-miR-3975	CLIP-seq
MIRT2076057	hsa-miR-4307	CLIP-seq
MIRT2302641	hsa-miR-4446-5p	CLIP-seq
MIRT2599317	hsa-miR-4755-5p	CLIP-seq
MIRT2599319	hsa-miR-623	CLIP-seq

Show/Hide all(12)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000159	Component	Protein phosphatase type 2A complex	IBA	21873635
GO:0005515	Function	Protein binding	IPI	15380617, 17540176, 18201571, 18782753, 19156129, 21699783, 21878643, 23555304, 24705354, 26496610, 27173435, 28330616, 30595372, 32814053
GO:0005634	Component	Nucleus	IBA	21873635
GO:0005737	Component	Cytoplasm	TAS	8703017
GO:0005829	Component	Cytosol	IBA	21873635
GO:0005829	Component	Cytosol	IDA
GO:0006470	Process	Protein dephosphorylation	IBA	21873635
GO:0007165	Process	Signal transduction	IEA
GO:0019888	Function	Protein phosphatase regulator activity	TAS	8703017
GO:0031952	Process	Regulation of protein autophosphorylation	IBA	21873635
GO:0043666	Process	Regulation of phosphoprotein phosphatase activity	IEA
GO:0072542	Function	Protein phosphatase activator activity	IBA	21873635

MIM	HGNC	e!Ensembl
601647	9313	ENSG00000154001

Protein

UniProt ID

Q16537

Protein name

Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform (PP2A B subunit isoform B'-epsilon) (PP2A B subunit isoform B56-epsilon) (PP2A B subunit isoform PR61-epsilon) (PP2A B subunit isoform R5-epsilon)

Protein function

The B regulatory subunit might modulate substrate selectivity and catalytic activity, and might also direct the localization of the catalytic enzyme to a particular subcellular compartment.

PDB

8UWB

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01603	B56	48 → 453	Protein phosphatase 2A regulatory B subunit (B56 family)	Family

Sequence

MSSAPTTPPSVDKVDGFSRKSVRKARQKRSQSSSQFRSQGKPIELTPLPLLKDVPSSEQP
ELFLKKLQQCCVIFDFMDTLSDLKMKEYKRSTLNELVDYITISRGCLTEQTYPEVVRMVS
CNIFRTLPPSDSNEFDPEEDEPTLEASWPHLQLVYEFFIRFLESQEFQPSIAKKYIDQKF
VLQLLELFDSEDPRERDYLKTVLHRIYGKFLGLRAFIRKQINNIFLRFVYETEHFNGVAE
LLEILGSIINGFALPLKAEHKQFLVKVLIPLHTVRSLSLFHAQLAYCIVQFLEKDPSLTE
PVIRGLMKFWPKTCSQKEVMFLGELEEILDVIEPSQFVKIQEPLFKQIAKCVSSPHFQVA
ERALYYWNNEYIMSLIEENSNVILPIMFSSLYRISKEHWNPAIVALVYNVLKAFMEMNST
MFDELTATYKSDRQREKKKEKEREELWKKLEDLELKRGLRRDGIIPT

Sequence length

467

Interactions

View interactions

Show/Hide Unknown Diseases (2)

Disease term	Disease name	Source
Unknown
Schizophrenia	Schizophrenia	GWAS
Bronchitis	Bronchitis	GWAS

Show/Hide Text Mining Associations (8)

Disease Name	Relationship Type	References
Associations from Text Mining
Breast Neoplasms	Associate	19890961
Colorectal Neoplasms	Associate	37175484
Leukemia Lymphocytic Chronic B Cell	Associate	21659360
Lung Neoplasms	Associate	24204789
Lymphoma Large B Cell Diffuse	Associate	27720936
Neoplasm Metastasis	Associate	37272097
Neoplasms	Associate	21659360, 37272097
Rectal Neoplasms	Associate	37175484

PPP2R5E (protein phosphatase 2 regulatory subunit B'epsilon)