Gene Gene information from NCBI Gene database.
Entrez ID 5529
Gene name Protein phosphatase 2 regulatory subunit B'epsilon
Gene symbol PPP2R5E
Synonyms (NCBI Gene)
B56EB56epsilon
Chromosome 14
Chromosome location 14q23.2
Summary The protein encoded by this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a co
miRNA miRNA information provided by mirtarbase database.
313
miRTarBase ID miRNA Experiments Reference
MIRT006743 hsa-miR-19b-3p Luciferase reporter assay 20190740
MIRT006743 hsa-miR-19b-3p Luciferase reporter assay 20190740
MIRT051983 hsa-let-7b-5p CLASH 23622248
MIRT051753 hsa-let-7c-5p CLASH 23622248
MIRT045699 hsa-miR-125a-5p CLASH 23622248
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
12
GO ID Ontology Definition Evidence Reference
GO:0000159 Component Protein phosphatase type 2A complex IBA
GO:0000159 Component Protein phosphatase type 2A complex IEA
GO:0005515 Function Protein binding IPI 15380617, 17540176, 18201571, 18782753, 19156129, 21699783, 21878643, 23555304, 24705354, 26496610, 27173435, 28330616, 30595372, 32814053, 33961781
GO:0005634 Component Nucleus IBA
GO:0005737 Component Cytoplasm IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
601647 9313 ENSG00000154001
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q16537
Protein name Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform (PP2A B subunit isoform B'-epsilon) (PP2A B subunit isoform B56-epsilon) (PP2A B subunit isoform PR61-epsilon) (PP2A B subunit isoform R5-epsilon)
Protein function The B regulatory subunit might modulate substrate selectivity and catalytic activity, and might also direct the localization of the catalytic enzyme to a particular subcellular compartment.
PDB 8UWB
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01603 B56 48 453 Protein phosphatase 2A regulatory B subunit (B56 family) Family
Sequence
Sequence length 467
Interactions View interactions