PPP2R3A (protein phosphatase 2 regulatory subunit B''alpha)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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5523 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Protein phosphatase 2 regulatory subunit B''alpha |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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PPP2R3A |
Synonyms (NCBI Gene)
Gene synonyms aliases
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PPP2R3, PR130, PR72 |
Chromosome
Chromosome number
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3 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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3q22.2-q22.3 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes one of the regulatory subunits of the protein phosphatase 2. Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phos |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||||||||||||||||
UniProt ID | Q06190 | |||||||||||||||
Protein name | Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha (PP2A subunit B isoform PR72/PR130) (PP2A subunit B isoform R3 isoform) (PP2A subunit B isoforms B''-PR72/PR130) (PP2A subunit B isoforms B72/B130) (Serine/threonine-protein phos | |||||||||||||||
Protein function | The B regulatory subunit might modulate substrate selectivity and catalytic activity, and might also direct the localization of the catalytic enzyme to a particular subcellular compartment. | |||||||||||||||
PDB | 4I5J , 4I5K | |||||||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Expressed in heart, brain, placenta, lung, muscle and kidney. | |||||||||||||||
Sequence |
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Sequence length | 1150 | |||||||||||||||
Interactions | View interactions |
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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