Gene Gene information from NCBI Gene database.
Entrez ID 5501
Gene name Protein phosphatase 1 catalytic subunit gamma
Gene symbol PPP1CC
Synonyms (NCBI Gene)
PP-1GPP1CPPP1G
Chromosome 12
Chromosome location 12q24.11
Summary The protein encoded by this gene belongs to the protein phosphatase family, PP1 subfamily. PP1 is an ubiquitous serine/threonine phosphatase that regulates many cellular processes, including cell division. It is expressed in mammalian cells as three close
miRNA miRNA information provided by mirtarbase database.
580
miRTarBase ID miRNA Experiments Reference
MIRT028665 hsa-miR-30a-5p Proteomics 18668040
MIRT050065 hsa-miR-26a-5p CLASH 23622248
MIRT050049 hsa-miR-26b-5p CLASH 23622248
MIRT049174 hsa-miR-92a-3p CLASH 23622248
MIRT046498 hsa-miR-15b-5p CLASH 23622248
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
69
GO ID Ontology Definition Evidence Reference
GO:0000070 Process Mitotic sister chromatid segregation TAS
GO:0000165 Process MAPK cascade TAS
GO:0000775 Component Chromosome, centromeric region IEA
GO:0000776 Component Kinetochore IEA
GO:0000781 Component Chromosome, telomeric region IDA 24270157
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
176914 9283 ENSG00000186298
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P36873
Protein name Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Protein function Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets (PubMed:17936702, PubMed:25012651). Protein phosphatase 1 (PP1) is essential for cell
PDB 1IT6 , 1JK7 , 1U32 , 2BCD , 2BDX , 4UT2 , 4UT3 , 5INB , 5J28 , 7SD0 , 8B5R
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF16891 STPPase_N 9 56 Serine-threonine protein phosphatase N-terminal domain Family
PF00149 Metallophos 57 252 Calcineurin-like phosphoesterase Domain
Sequence
Sequence length 323
Interactions View interactions