PPAT (phosphoribosyl pyrophosphate amidotransferase)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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5471 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Phosphoribosyl pyrophosphate amidotransferase |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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PPAT |
Synonyms (NCBI Gene)
Gene synonyms aliases
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ATASE, GPAT, PRAT |
Chromosome
Chromosome number
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4 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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4q12 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. It is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosythetic pathway. This gene and PAICS/AIRC gene, a b |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | Q06203 | ||||||||||
Protein name | Amidophosphoribosyltransferase (ATase) (EC 2.4.2.14) (Glutamine phosphoribosylpyrophosphate amidotransferase) (GPAT) | ||||||||||
Protein function | Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | ||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Ubiquitously expressed. {ECO:0000269|PubMed:8380692}. | ||||||||||
Sequence |
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Sequence length | 517 | ||||||||||
Interactions | View interactions |
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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