Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs Transcription factors Other IDs Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	23175
Gene name Gene Name - the full gene name approved by the HGNC.	Lipin 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	LPIN1
Synonyms (NCBI Gene) Gene synonyms aliases	PAP1
Chromosome Chromosome number	2
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	2p25.1
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is re

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SNP ID	Visualize variation	Clinical significance	Consequence
rs119480071	G>T	Pathogenic	Non coding transcript variant, stop gained, coding sequence variant
rs119480072	C>T	Pathogenic	Non coding transcript variant, stop gained, coding sequence variant
rs119480073	C>A,T	Pathogenic	Non coding transcript variant, coding sequence variant, stop gained, genic downstream transcript variant, synonymous variant
rs730880306	T>C	Pathogenic	Splice donor variant, downstream transcript variant, genic downstream transcript variant
rs886041544	->GA	Pathogenic	Coding sequence variant, frameshift variant, non coding transcript variant, 3 prime UTR variant
rs1572770217	G>-	Pathogenic	Coding sequence variant, non coding transcript variant, frameshift variant
rs1572931008	->GTGTCACCACGCAGTACCA	Likely-pathogenic	Coding sequence variant, non coding transcript variant, genic downstream transcript variant, frameshift variant

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miRTarBase ID	miRNA	Experiments	Reference
MIRT018934	hsa-miR-335-5p	Microarray	18185580
MIRT050981	hsa-miR-17-5p	CLASH	23622248
MIRT049016	hsa-miR-92a-3p	CLASH	23622248
MIRT437695	hsa-miR-27a-3p	Microarray, qRT-PCR	22815788
MIRT437704	hsa-miR-27b-3p	Microarray, qRT-PCR	22815788
MIRT440316	hsa-miR-485-5p	HITS-CLIP	24374217
MIRT440317	hsa-miR-432-3p	HITS-CLIP	24374217
MIRT440316	hsa-miR-485-5p	HITS-CLIP	24374217
MIRT440317	hsa-miR-432-3p	HITS-CLIP	24374217
MIRT1116256	hsa-miR-105	CLIP-seq
MIRT1116257	hsa-miR-106a	CLIP-seq
MIRT1116258	hsa-miR-106b	CLIP-seq
MIRT1116259	hsa-miR-122	CLIP-seq
MIRT1116260	hsa-miR-1237	CLIP-seq
MIRT1116261	hsa-miR-1271	CLIP-seq
MIRT1116262	hsa-miR-1286	CLIP-seq
MIRT1116263	hsa-miR-130a	CLIP-seq
MIRT1116264	hsa-miR-130b	CLIP-seq
MIRT1116265	hsa-miR-137	CLIP-seq
MIRT1116266	hsa-miR-142-5p	CLIP-seq
MIRT1116267	hsa-miR-17	CLIP-seq
MIRT1116268	hsa-miR-182	CLIP-seq
MIRT1116269	hsa-miR-199a-3p	CLIP-seq
MIRT1116270	hsa-miR-199b-3p	CLIP-seq
MIRT1116271	hsa-miR-20a	CLIP-seq
MIRT1116272	hsa-miR-20b	CLIP-seq
MIRT1116273	hsa-miR-218	CLIP-seq
MIRT1116274	hsa-miR-2278	CLIP-seq
MIRT1116275	hsa-miR-25	CLIP-seq
MIRT1116276	hsa-miR-27a	CLIP-seq
MIRT1116277	hsa-miR-27b	CLIP-seq
MIRT1116278	hsa-miR-300	CLIP-seq
MIRT1116279	hsa-miR-301a	CLIP-seq
MIRT1116280	hsa-miR-301b	CLIP-seq
MIRT1116281	hsa-miR-3123	CLIP-seq
MIRT1116282	hsa-miR-3129-5p	CLIP-seq
MIRT1116283	hsa-miR-3135	CLIP-seq
MIRT1116284	hsa-miR-3135b	CLIP-seq
MIRT1116285	hsa-miR-3159	CLIP-seq
MIRT1116286	hsa-miR-3163	CLIP-seq
MIRT1116287	hsa-miR-32	CLIP-seq
MIRT1116288	hsa-miR-324-5p	CLIP-seq
MIRT1116289	hsa-miR-3545-3p	CLIP-seq
MIRT1116290	hsa-miR-3607-5p	CLIP-seq
MIRT1116291	hsa-miR-3609	CLIP-seq
MIRT1116292	hsa-miR-363	CLIP-seq
MIRT1116293	hsa-miR-3646	CLIP-seq
MIRT1116294	hsa-miR-3652	CLIP-seq
MIRT1116295	hsa-miR-3664-5p	CLIP-seq
MIRT1116296	hsa-miR-3666	CLIP-seq
MIRT1116297	hsa-miR-367	CLIP-seq
MIRT1116298	hsa-miR-381	CLIP-seq
MIRT1116299	hsa-miR-3910	CLIP-seq
MIRT1116300	hsa-miR-4269	CLIP-seq
MIRT1116301	hsa-miR-4282	CLIP-seq
MIRT1116302	hsa-miR-4284	CLIP-seq
MIRT1116303	hsa-miR-4295	CLIP-seq
MIRT1116304	hsa-miR-4310	CLIP-seq
MIRT1116305	hsa-miR-4311	CLIP-seq
MIRT1116306	hsa-miR-4317	CLIP-seq
MIRT1116307	hsa-miR-4323	CLIP-seq
MIRT1116308	hsa-miR-4430	CLIP-seq
MIRT1116309	hsa-miR-4436b-3p	CLIP-seq
MIRT1116310	hsa-miR-4464	CLIP-seq
MIRT1116311	hsa-miR-4470	CLIP-seq
MIRT1116312	hsa-miR-4501	CLIP-seq
MIRT1116313	hsa-miR-4504	CLIP-seq
MIRT1116314	hsa-miR-4514	CLIP-seq
MIRT1116315	hsa-miR-4521	CLIP-seq
MIRT1116316	hsa-miR-4528	CLIP-seq
MIRT1116317	hsa-miR-454	CLIP-seq
MIRT1116318	hsa-miR-4635	CLIP-seq
MIRT1116319	hsa-miR-4638-5p	CLIP-seq
MIRT1116320	hsa-miR-4642	CLIP-seq
MIRT1116321	hsa-miR-4666-3p	CLIP-seq
MIRT1116322	hsa-miR-4671-3p	CLIP-seq
MIRT1116323	hsa-miR-4692	CLIP-seq
MIRT1116324	hsa-miR-4711-5p	CLIP-seq
MIRT1116325	hsa-miR-4712-3p	CLIP-seq
MIRT1116326	hsa-miR-4712-5p	CLIP-seq
MIRT1116327	hsa-miR-4714-5p	CLIP-seq
MIRT1116328	hsa-miR-4717-3p	CLIP-seq
MIRT1116329	hsa-miR-4727-5p	CLIP-seq
MIRT1116330	hsa-miR-4729	CLIP-seq
MIRT1116331	hsa-miR-4738-3p	CLIP-seq
MIRT1116332	hsa-miR-4742-5p	CLIP-seq
MIRT1116333	hsa-miR-4748	CLIP-seq
MIRT1116334	hsa-miR-4753-3p	CLIP-seq
MIRT1116335	hsa-miR-4753-5p	CLIP-seq
MIRT1116336	hsa-miR-4761-3p	CLIP-seq
MIRT1116337	hsa-miR-4772-3p	CLIP-seq
MIRT1116338	hsa-miR-4796-3p	CLIP-seq
MIRT1116339	hsa-miR-4803	CLIP-seq
MIRT1116340	hsa-miR-488	CLIP-seq
MIRT1116341	hsa-miR-511	CLIP-seq
MIRT1116342	hsa-miR-513a-5p	CLIP-seq
MIRT1116343	hsa-miR-515-5p	CLIP-seq
MIRT1116344	hsa-miR-518a-3p	CLIP-seq
MIRT1116345	hsa-miR-518a-5p	CLIP-seq
MIRT1116346	hsa-miR-518b	CLIP-seq
MIRT1116347	hsa-miR-518c	CLIP-seq
MIRT1116348	hsa-miR-518d-3p	CLIP-seq
MIRT1116349	hsa-miR-518f	CLIP-seq
MIRT1116350	hsa-miR-519d	CLIP-seq
MIRT1116351	hsa-miR-526b	CLIP-seq
MIRT1116352	hsa-miR-527	CLIP-seq
MIRT1116353	hsa-miR-539	CLIP-seq
MIRT1116354	hsa-miR-542-3p	CLIP-seq
MIRT1116355	hsa-miR-548ah	CLIP-seq
MIRT1116356	hsa-miR-548an	CLIP-seq
MIRT1116357	hsa-miR-550b	CLIP-seq
MIRT1116358	hsa-miR-556-5p	CLIP-seq
MIRT1116359	hsa-miR-562	CLIP-seq
MIRT1116360	hsa-miR-577	CLIP-seq
MIRT1116361	hsa-miR-579	CLIP-seq
MIRT1116362	hsa-miR-582-5p	CLIP-seq
MIRT1116363	hsa-miR-587	CLIP-seq
MIRT1116364	hsa-miR-595	CLIP-seq
MIRT1116365	hsa-miR-600	CLIP-seq
MIRT1116366	hsa-miR-610	CLIP-seq
MIRT1116367	hsa-miR-636	CLIP-seq
MIRT1116368	hsa-miR-640	CLIP-seq
MIRT1116369	hsa-miR-648	CLIP-seq
MIRT1116370	hsa-miR-664	CLIP-seq
MIRT1116371	hsa-miR-668	CLIP-seq
MIRT1116372	hsa-miR-770-5p	CLIP-seq
MIRT1116373	hsa-miR-891b	CLIP-seq
MIRT1116374	hsa-miR-924	CLIP-seq
MIRT1116375	hsa-miR-92a	CLIP-seq
MIRT1116376	hsa-miR-92b	CLIP-seq
MIRT1116377	hsa-miR-93	CLIP-seq
MIRT1116378	hsa-miR-940	CLIP-seq
MIRT1116379	hsa-miR-944	CLIP-seq
MIRT1116380	hsa-miR-96	CLIP-seq
MIRT1116259	hsa-miR-122	CLIP-seq
MIRT2032810	hsa-miR-1272	CLIP-seq
MIRT1116262	hsa-miR-1286	CLIP-seq
MIRT2032811	hsa-miR-1302	CLIP-seq
MIRT1116263	hsa-miR-130a	CLIP-seq
MIRT1116264	hsa-miR-130b	CLIP-seq
MIRT2032812	hsa-miR-1909	CLIP-seq
MIRT1116269	hsa-miR-199a-3p	CLIP-seq
MIRT1116270	hsa-miR-199b-3p	CLIP-seq
MIRT2032813	hsa-miR-2467-3p	CLIP-seq
MIRT1116276	hsa-miR-27a	CLIP-seq
MIRT1116277	hsa-miR-27b	CLIP-seq
MIRT2032814	hsa-miR-29a	CLIP-seq
MIRT2032815	hsa-miR-29b	CLIP-seq
MIRT2032816	hsa-miR-29c	CLIP-seq
MIRT1116279	hsa-miR-301a	CLIP-seq
MIRT1116280	hsa-miR-301b	CLIP-seq
MIRT2032817	hsa-miR-3065-3p	CLIP-seq
MIRT2032818	hsa-miR-31	CLIP-seq
MIRT2032819	hsa-miR-3122	CLIP-seq
MIRT2032820	hsa-miR-3128	CLIP-seq
MIRT1116282	hsa-miR-3129-5p	CLIP-seq
MIRT1116284	hsa-miR-3135b	CLIP-seq
MIRT2032821	hsa-miR-3143	CLIP-seq
MIRT2032822	hsa-miR-3155	CLIP-seq
MIRT2032823	hsa-miR-3155b	CLIP-seq
MIRT2032824	hsa-miR-3194-3p	CLIP-seq
MIRT1116288	hsa-miR-324-5p	CLIP-seq
MIRT2032825	hsa-miR-3606	CLIP-seq
MIRT1116294	hsa-miR-3652	CLIP-seq
MIRT1116295	hsa-miR-3664-5p	CLIP-seq
MIRT1116296	hsa-miR-3666	CLIP-seq
MIRT2032826	hsa-miR-3714	CLIP-seq
MIRT2032827	hsa-miR-3913-5p	CLIP-seq
MIRT1116300	hsa-miR-4269	CLIP-seq
MIRT1116302	hsa-miR-4284	CLIP-seq
MIRT1116303	hsa-miR-4295	CLIP-seq
MIRT2032828	hsa-miR-4298	CLIP-seq
MIRT1116308	hsa-miR-4430	CLIP-seq
MIRT1116313	hsa-miR-4504	CLIP-seq
MIRT2032829	hsa-miR-4506	CLIP-seq
MIRT1116314	hsa-miR-4514	CLIP-seq
MIRT1116317	hsa-miR-454	CLIP-seq
MIRT1116319	hsa-miR-4638-5p	CLIP-seq
MIRT1116322	hsa-miR-4671-3p	CLIP-seq
MIRT1116323	hsa-miR-4692	CLIP-seq
MIRT1116327	hsa-miR-4714-5p	CLIP-seq
MIRT1116332	hsa-miR-4742-5p	CLIP-seq
MIRT2032830	hsa-miR-4759	CLIP-seq
MIRT1116337	hsa-miR-4772-3p	CLIP-seq
MIRT2032831	hsa-miR-4793-3p	CLIP-seq
MIRT2032832	hsa-miR-484	CLIP-seq
MIRT1116342	hsa-miR-513a-5p	CLIP-seq
MIRT1116345	hsa-miR-518a-5p	CLIP-seq
MIRT1116352	hsa-miR-527	CLIP-seq
MIRT2032833	hsa-miR-543	CLIP-seq
MIRT1116357	hsa-miR-550b	CLIP-seq
MIRT1116378	hsa-miR-940	CLIP-seq
MIRT1116379	hsa-miR-944	CLIP-seq
MIRT1116256	hsa-miR-105	CLIP-seq
MIRT2263175	hsa-miR-1179	CLIP-seq
MIRT1116259	hsa-miR-122	CLIP-seq
MIRT2263176	hsa-miR-1254	CLIP-seq
MIRT2263177	hsa-miR-1270	CLIP-seq
MIRT1116261	hsa-miR-1271	CLIP-seq
MIRT1116263	hsa-miR-130a	CLIP-seq
MIRT1116264	hsa-miR-130b	CLIP-seq
MIRT2263178	hsa-miR-147	CLIP-seq
MIRT2263179	hsa-miR-150	CLIP-seq
MIRT2263180	hsa-miR-1537	CLIP-seq
MIRT1116268	hsa-miR-182	CLIP-seq
MIRT2263181	hsa-miR-185	CLIP-seq
MIRT2263182	hsa-miR-186	CLIP-seq
MIRT1116269	hsa-miR-199a-3p	CLIP-seq
MIRT2263183	hsa-miR-199a-5p	CLIP-seq
MIRT1116270	hsa-miR-199b-3p	CLIP-seq
MIRT2263184	hsa-miR-199b-5p	CLIP-seq
MIRT2263185	hsa-miR-200b	CLIP-seq
MIRT2263186	hsa-miR-200c	CLIP-seq
MIRT2263187	hsa-miR-203	CLIP-seq
MIRT2263188	hsa-miR-21	CLIP-seq
MIRT2263189	hsa-miR-23a	CLIP-seq
MIRT2263190	hsa-miR-23b	CLIP-seq
MIRT2263191	hsa-miR-23c	CLIP-seq
MIRT1116276	hsa-miR-27a	CLIP-seq
MIRT1116277	hsa-miR-27b	CLIP-seq
MIRT1116279	hsa-miR-301a	CLIP-seq
MIRT1116280	hsa-miR-301b	CLIP-seq
MIRT2032818	hsa-miR-31	CLIP-seq
MIRT2263192	hsa-miR-3116	CLIP-seq
MIRT2263193	hsa-miR-3120-3p	CLIP-seq
MIRT2263194	hsa-miR-3121-5p	CLIP-seq
MIRT2032820	hsa-miR-3128	CLIP-seq
MIRT1116282	hsa-miR-3129-5p	CLIP-seq
MIRT1116284	hsa-miR-3135b	CLIP-seq
MIRT2032822	hsa-miR-3155	CLIP-seq
MIRT2032823	hsa-miR-3155b	CLIP-seq
MIRT1116285	hsa-miR-3159	CLIP-seq
MIRT1116288	hsa-miR-324-5p	CLIP-seq
MIRT2263195	hsa-miR-338-3p	CLIP-seq
MIRT1116294	hsa-miR-3652	CLIP-seq
MIRT2263196	hsa-miR-3662	CLIP-seq
MIRT1116295	hsa-miR-3664-5p	CLIP-seq
MIRT1116296	hsa-miR-3666	CLIP-seq
MIRT2263197	hsa-miR-3672	CLIP-seq
MIRT1116299	hsa-miR-3910	CLIP-seq
MIRT2263198	hsa-miR-3911	CLIP-seq
MIRT2263199	hsa-miR-4273	CLIP-seq
MIRT1116301	hsa-miR-4282	CLIP-seq
MIRT2263200	hsa-miR-429	CLIP-seq
MIRT1116303	hsa-miR-4295	CLIP-seq
MIRT2263201	hsa-miR-4306	CLIP-seq
MIRT1116304	hsa-miR-4310	CLIP-seq
MIRT1116308	hsa-miR-4430	CLIP-seq
MIRT1116309	hsa-miR-4436b-3p	CLIP-seq
MIRT1116311	hsa-miR-4470	CLIP-seq
MIRT1116313	hsa-miR-4504	CLIP-seq
MIRT1116316	hsa-miR-4528	CLIP-seq
MIRT2263202	hsa-miR-4530	CLIP-seq
MIRT2263203	hsa-miR-4531	CLIP-seq
MIRT2263204	hsa-miR-4539	CLIP-seq
MIRT1116317	hsa-miR-454	CLIP-seq
MIRT2263205	hsa-miR-4641	CLIP-seq
MIRT1116320	hsa-miR-4642	CLIP-seq
MIRT2263206	hsa-miR-4644	CLIP-seq
MIRT1116322	hsa-miR-4671-3p	CLIP-seq
MIRT2263207	hsa-miR-4676-5p	CLIP-seq
MIRT2263208	hsa-miR-4677-5p	CLIP-seq
MIRT1116326	hsa-miR-4712-5p	CLIP-seq
MIRT1116327	hsa-miR-4714-5p	CLIP-seq
MIRT1116336	hsa-miR-4761-3p	CLIP-seq
MIRT2032831	hsa-miR-4793-3p	CLIP-seq
MIRT2032832	hsa-miR-484	CLIP-seq
MIRT1116342	hsa-miR-513a-5p	CLIP-seq
MIRT1116345	hsa-miR-518a-5p	CLIP-seq
MIRT1116352	hsa-miR-527	CLIP-seq
MIRT2263209	hsa-miR-545	CLIP-seq
MIRT2263210	hsa-miR-548aa	CLIP-seq
MIRT1116356	hsa-miR-548an	CLIP-seq
MIRT2263211	hsa-miR-548c-3p	CLIP-seq
MIRT1116358	hsa-miR-556-5p	CLIP-seq
MIRT1116359	hsa-miR-562	CLIP-seq
MIRT2263212	hsa-miR-575	CLIP-seq
MIRT1116361	hsa-miR-579	CLIP-seq
MIRT1116362	hsa-miR-582-5p	CLIP-seq
MIRT1116363	hsa-miR-587	CLIP-seq
MIRT2263213	hsa-miR-590-5p	CLIP-seq
MIRT1116364	hsa-miR-595	CLIP-seq
MIRT2263214	hsa-miR-620	CLIP-seq
MIRT2263215	hsa-miR-644	CLIP-seq
MIRT1116369	hsa-miR-648	CLIP-seq
MIRT1116370	hsa-miR-664	CLIP-seq
MIRT1116371	hsa-miR-668	CLIP-seq
MIRT1116372	hsa-miR-770-5p	CLIP-seq
MIRT1116373	hsa-miR-891b	CLIP-seq
MIRT2263216	hsa-miR-9	CLIP-seq
MIRT1116380	hsa-miR-96	CLIP-seq
MIRT1116259	hsa-miR-122	CLIP-seq
MIRT2390302	hsa-miR-1299	CLIP-seq
MIRT1116263	hsa-miR-130a	CLIP-seq
MIRT1116264	hsa-miR-130b	CLIP-seq
MIRT2390303	hsa-miR-134	CLIP-seq
MIRT1116269	hsa-miR-199a-3p	CLIP-seq
MIRT1116270	hsa-miR-199b-3p	CLIP-seq
MIRT2032814	hsa-miR-29a	CLIP-seq
MIRT2032815	hsa-miR-29b	CLIP-seq
MIRT2032816	hsa-miR-29c	CLIP-seq
MIRT1116279	hsa-miR-301a	CLIP-seq
MIRT1116280	hsa-miR-301b	CLIP-seq
MIRT2032817	hsa-miR-3065-3p	CLIP-seq
MIRT2390304	hsa-miR-3118	CLIP-seq
MIRT1116282	hsa-miR-3129-5p	CLIP-seq
MIRT1116284	hsa-miR-3135b	CLIP-seq
MIRT2390305	hsa-miR-3164	CLIP-seq
MIRT1116294	hsa-miR-3652	CLIP-seq
MIRT1116295	hsa-miR-3664-5p	CLIP-seq
MIRT1116296	hsa-miR-3666	CLIP-seq
MIRT2390306	hsa-miR-3978	CLIP-seq
MIRT1116303	hsa-miR-4295	CLIP-seq
MIRT1116308	hsa-miR-4430	CLIP-seq
MIRT1116317	hsa-miR-454	CLIP-seq
MIRT1116322	hsa-miR-4671-3p	CLIP-seq
MIRT1116326	hsa-miR-4712-5p	CLIP-seq
MIRT2390307	hsa-miR-4782-5p	CLIP-seq
MIRT2390308	hsa-miR-516b	CLIP-seq
MIRT1116361	hsa-miR-579	CLIP-seq
MIRT1116372	hsa-miR-770-5p	CLIP-seq
MIRT2390309	hsa-miR-875-3p	CLIP-seq
MIRT2430847	hsa-miR-489	CLIP-seq
MIRT2430848	hsa-miR-514	CLIP-seq
MIRT2453250	hsa-miR-3665	CLIP-seq
MIRT2032826	hsa-miR-3714	CLIP-seq
MIRT2453251	hsa-miR-3934	CLIP-seq
MIRT2453252	hsa-miR-3942-3p	CLIP-seq
MIRT2453253	hsa-miR-4736	CLIP-seq
MIRT2453254	hsa-miR-4786-3p	CLIP-seq
MIRT1116378	hsa-miR-940	CLIP-seq
MIRT2562553	hsa-miR-10a	CLIP-seq
MIRT2562554	hsa-miR-10b	CLIP-seq
MIRT2562555	hsa-miR-1183	CLIP-seq
MIRT1116259	hsa-miR-122	CLIP-seq
MIRT1116260	hsa-miR-1237	CLIP-seq
MIRT2263176	hsa-miR-1254	CLIP-seq
MIRT1116262	hsa-miR-1286	CLIP-seq
MIRT2562556	hsa-miR-1287	CLIP-seq
MIRT2390302	hsa-miR-1299	CLIP-seq
MIRT1116263	hsa-miR-130a	CLIP-seq
MIRT1116264	hsa-miR-130b	CLIP-seq
MIRT2562557	hsa-miR-1324	CLIP-seq
MIRT2390303	hsa-miR-134	CLIP-seq
MIRT2562558	hsa-miR-139-5p	CLIP-seq
MIRT2562559	hsa-miR-1908	CLIP-seq
MIRT2562560	hsa-miR-198	CLIP-seq
MIRT1116269	hsa-miR-199a-3p	CLIP-seq
MIRT1116270	hsa-miR-199b-3p	CLIP-seq
MIRT2263185	hsa-miR-200b	CLIP-seq
MIRT2263186	hsa-miR-200c	CLIP-seq
MIRT1116276	hsa-miR-27a	CLIP-seq
MIRT1116277	hsa-miR-27b	CLIP-seq
MIRT1116279	hsa-miR-301a	CLIP-seq
MIRT1116280	hsa-miR-301b	CLIP-seq
MIRT2263192	hsa-miR-3116	CLIP-seq
MIRT2390304	hsa-miR-3118	CLIP-seq
MIRT2562561	hsa-miR-3127-5p	CLIP-seq
MIRT1116282	hsa-miR-3129-5p	CLIP-seq
MIRT2562562	hsa-miR-3130-3p	CLIP-seq
MIRT1116283	hsa-miR-3135	CLIP-seq
MIRT1116284	hsa-miR-3135b	CLIP-seq
MIRT1116285	hsa-miR-3159	CLIP-seq
MIRT2390305	hsa-miR-3164	CLIP-seq
MIRT2562563	hsa-miR-3190	CLIP-seq
MIRT2032824	hsa-miR-3194-3p	CLIP-seq
MIRT2562564	hsa-miR-3200-5p	CLIP-seq
MIRT2562565	hsa-miR-339-5p	CLIP-seq
MIRT2562566	hsa-miR-361-5p	CLIP-seq
MIRT1116294	hsa-miR-3652	CLIP-seq
MIRT1116296	hsa-miR-3666	CLIP-seq
MIRT2263197	hsa-miR-3672	CLIP-seq
MIRT2562567	hsa-miR-3676	CLIP-seq
MIRT2562568	hsa-miR-3690	CLIP-seq
MIRT2562569	hsa-miR-3691-3p	CLIP-seq
MIRT2032826	hsa-miR-3714	CLIP-seq
MIRT2562570	hsa-miR-374c	CLIP-seq
MIRT2562571	hsa-miR-3919	CLIP-seq
MIRT2562572	hsa-miR-3922-5p	CLIP-seq
MIRT2562573	hsa-miR-3936	CLIP-seq
MIRT2390306	hsa-miR-3978	CLIP-seq
MIRT2562574	hsa-miR-4251	CLIP-seq
MIRT1116300	hsa-miR-4269	CLIP-seq
MIRT1116301	hsa-miR-4282	CLIP-seq
MIRT1116302	hsa-miR-4284	CLIP-seq
MIRT2263200	hsa-miR-429	CLIP-seq
MIRT1116303	hsa-miR-4295	CLIP-seq
MIRT1116307	hsa-miR-4323	CLIP-seq
MIRT2562575	hsa-miR-4329	CLIP-seq
MIRT2562576	hsa-miR-4330	CLIP-seq
MIRT2562577	hsa-miR-4422	CLIP-seq
MIRT1116308	hsa-miR-4430	CLIP-seq
MIRT2562578	hsa-miR-4457	CLIP-seq
MIRT1116310	hsa-miR-4464	CLIP-seq
MIRT2562579	hsa-miR-4477b	CLIP-seq
MIRT2562580	hsa-miR-4480	CLIP-seq
MIRT2562581	hsa-miR-4491	CLIP-seq
MIRT1116314	hsa-miR-4514	CLIP-seq
MIRT1116317	hsa-miR-454	CLIP-seq
MIRT1116319	hsa-miR-4638-5p	CLIP-seq
MIRT2562582	hsa-miR-4645-3p	CLIP-seq
MIRT2562583	hsa-miR-4649-3p	CLIP-seq
MIRT2562584	hsa-miR-4650-5p	CLIP-seq
MIRT2562585	hsa-miR-4657	CLIP-seq
MIRT1116322	hsa-miR-4671-3p	CLIP-seq
MIRT2562586	hsa-miR-4687-5p	CLIP-seq
MIRT2562587	hsa-miR-4690-5p	CLIP-seq
MIRT1116323	hsa-miR-4692	CLIP-seq
MIRT2562588	hsa-miR-4693-3p	CLIP-seq
MIRT2562589	hsa-miR-4698	CLIP-seq
MIRT2562590	hsa-miR-4706	CLIP-seq
MIRT1116328	hsa-miR-4717-3p	CLIP-seq
MIRT2562591	hsa-miR-4725-5p	CLIP-seq
MIRT1116329	hsa-miR-4727-5p	CLIP-seq
MIRT1116332	hsa-miR-4742-5p	CLIP-seq
MIRT2562592	hsa-miR-4743	CLIP-seq
MIRT1116333	hsa-miR-4748	CLIP-seq
MIRT2562593	hsa-miR-4749-5p	CLIP-seq
MIRT1116334	hsa-miR-4753-3p	CLIP-seq
MIRT1116335	hsa-miR-4753-5p	CLIP-seq
MIRT2562594	hsa-miR-4755-3p	CLIP-seq
MIRT2562595	hsa-miR-4756-3p	CLIP-seq
MIRT2032830	hsa-miR-4759	CLIP-seq
MIRT1116337	hsa-miR-4772-3p	CLIP-seq
MIRT2390307	hsa-miR-4782-5p	CLIP-seq
MIRT2562596	hsa-miR-4783-3p	CLIP-seq
MIRT2562597	hsa-miR-4789-3p	CLIP-seq
MIRT2032831	hsa-miR-4793-3p	CLIP-seq
MIRT2562598	hsa-miR-499-3p	CLIP-seq
MIRT2562599	hsa-miR-499a-3p	CLIP-seq
MIRT2562600	hsa-miR-504	CLIP-seq
MIRT1116342	hsa-miR-513a-5p	CLIP-seq
MIRT2390308	hsa-miR-516b	CLIP-seq
MIRT1116345	hsa-miR-518a-5p	CLIP-seq
MIRT1116352	hsa-miR-527	CLIP-seq
MIRT2263209	hsa-miR-545	CLIP-seq
MIRT2562601	hsa-miR-548ag	CLIP-seq
MIRT2562602	hsa-miR-548ai	CLIP-seq
MIRT1116356	hsa-miR-548an	CLIP-seq
MIRT1116359	hsa-miR-562	CLIP-seq
MIRT2562603	hsa-miR-574-5p	CLIP-seq
MIRT1116361	hsa-miR-579	CLIP-seq
MIRT2562604	hsa-miR-642b	CLIP-seq
MIRT2562605	hsa-miR-655	CLIP-seq
MIRT2562606	hsa-miR-656	CLIP-seq
MIRT2562607	hsa-miR-663	CLIP-seq
MIRT1116370	hsa-miR-664	CLIP-seq
MIRT1116371	hsa-miR-668	CLIP-seq
MIRT2562608	hsa-miR-676	CLIP-seq
MIRT2562609	hsa-miR-711	CLIP-seq
MIRT2562610	hsa-miR-769-5p	CLIP-seq
MIRT2390309	hsa-miR-875-3p	CLIP-seq
MIRT2562611	hsa-miR-885-3p	CLIP-seq
MIRT2562612	hsa-miR-889	CLIP-seq
MIRT1116378	hsa-miR-940	CLIP-seq
MIRT1116379	hsa-miR-944	CLIP-seq
MIRT2562553	hsa-miR-10a	CLIP-seq
MIRT2562554	hsa-miR-10b	CLIP-seq
MIRT2562555	hsa-miR-1183	CLIP-seq
MIRT1116259	hsa-miR-122	CLIP-seq
MIRT1116260	hsa-miR-1237	CLIP-seq
MIRT2263176	hsa-miR-1254	CLIP-seq
MIRT1116262	hsa-miR-1286	CLIP-seq
MIRT2562556	hsa-miR-1287	CLIP-seq
MIRT2390302	hsa-miR-1299	CLIP-seq
MIRT1116263	hsa-miR-130a	CLIP-seq
MIRT1116264	hsa-miR-130b	CLIP-seq
MIRT2562557	hsa-miR-1324	CLIP-seq
MIRT2390303	hsa-miR-134	CLIP-seq
MIRT2562559	hsa-miR-1908	CLIP-seq
MIRT2562560	hsa-miR-198	CLIP-seq
MIRT1116269	hsa-miR-199a-3p	CLIP-seq
MIRT1116270	hsa-miR-199b-3p	CLIP-seq
MIRT2263185	hsa-miR-200b	CLIP-seq
MIRT2263186	hsa-miR-200c	CLIP-seq
MIRT1116276	hsa-miR-27a	CLIP-seq
MIRT1116277	hsa-miR-27b	CLIP-seq
MIRT1116279	hsa-miR-301a	CLIP-seq
MIRT1116280	hsa-miR-301b	CLIP-seq
MIRT2263192	hsa-miR-3116	CLIP-seq
MIRT2390304	hsa-miR-3118	CLIP-seq
MIRT2562561	hsa-miR-3127-5p	CLIP-seq
MIRT1116282	hsa-miR-3129-5p	CLIP-seq
MIRT2562562	hsa-miR-3130-3p	CLIP-seq
MIRT1116283	hsa-miR-3135	CLIP-seq
MIRT1116284	hsa-miR-3135b	CLIP-seq
MIRT2390305	hsa-miR-3164	CLIP-seq
MIRT2562563	hsa-miR-3190	CLIP-seq
MIRT2032824	hsa-miR-3194-3p	CLIP-seq
MIRT2562564	hsa-miR-3200-5p	CLIP-seq
MIRT2562565	hsa-miR-339-5p	CLIP-seq
MIRT1116294	hsa-miR-3652	CLIP-seq
MIRT1116296	hsa-miR-3666	CLIP-seq
MIRT2263197	hsa-miR-3672	CLIP-seq
MIRT2562567	hsa-miR-3676	CLIP-seq
MIRT2562568	hsa-miR-3690	CLIP-seq
MIRT2562569	hsa-miR-3691-3p	CLIP-seq
MIRT2562570	hsa-miR-374c	CLIP-seq
MIRT2562572	hsa-miR-3922-5p	CLIP-seq
MIRT2562573	hsa-miR-3936	CLIP-seq
MIRT2390306	hsa-miR-3978	CLIP-seq
MIRT2562574	hsa-miR-4251	CLIP-seq
MIRT1116300	hsa-miR-4269	CLIP-seq
MIRT1116301	hsa-miR-4282	CLIP-seq
MIRT1116302	hsa-miR-4284	CLIP-seq
MIRT2263200	hsa-miR-429	CLIP-seq
MIRT1116303	hsa-miR-4295	CLIP-seq
MIRT1116307	hsa-miR-4323	CLIP-seq
MIRT2562575	hsa-miR-4329	CLIP-seq
MIRT2562577	hsa-miR-4422	CLIP-seq
MIRT1116308	hsa-miR-4430	CLIP-seq
MIRT2562578	hsa-miR-4457	CLIP-seq
MIRT1116310	hsa-miR-4464	CLIP-seq
MIRT2562579	hsa-miR-4477b	CLIP-seq
MIRT2562580	hsa-miR-4480	CLIP-seq
MIRT2562581	hsa-miR-4491	CLIP-seq
MIRT1116314	hsa-miR-4514	CLIP-seq
MIRT1116317	hsa-miR-454	CLIP-seq
MIRT1116319	hsa-miR-4638-5p	CLIP-seq
MIRT2562583	hsa-miR-4649-3p	CLIP-seq
MIRT2562584	hsa-miR-4650-5p	CLIP-seq
MIRT2562585	hsa-miR-4657	CLIP-seq
MIRT1116322	hsa-miR-4671-3p	CLIP-seq
MIRT2562586	hsa-miR-4687-5p	CLIP-seq
MIRT2562587	hsa-miR-4690-5p	CLIP-seq
MIRT1116323	hsa-miR-4692	CLIP-seq
MIRT2562588	hsa-miR-4693-3p	CLIP-seq
MIRT2562589	hsa-miR-4698	CLIP-seq
MIRT2562590	hsa-miR-4706	CLIP-seq
MIRT2684086	hsa-miR-4713-3p	CLIP-seq
MIRT2562591	hsa-miR-4725-5p	CLIP-seq
MIRT1116329	hsa-miR-4727-5p	CLIP-seq
MIRT1116332	hsa-miR-4742-5p	CLIP-seq
MIRT2562592	hsa-miR-4743	CLIP-seq
MIRT1116333	hsa-miR-4748	CLIP-seq
MIRT2562593	hsa-miR-4749-5p	CLIP-seq
MIRT1116334	hsa-miR-4753-3p	CLIP-seq
MIRT1116335	hsa-miR-4753-5p	CLIP-seq
MIRT2562594	hsa-miR-4755-3p	CLIP-seq
MIRT2032830	hsa-miR-4759	CLIP-seq
MIRT1116337	hsa-miR-4772-3p	CLIP-seq
MIRT2390307	hsa-miR-4782-5p	CLIP-seq
MIRT2562596	hsa-miR-4783-3p	CLIP-seq
MIRT2032831	hsa-miR-4793-3p	CLIP-seq
MIRT2562598	hsa-miR-499-3p	CLIP-seq
MIRT2562599	hsa-miR-499a-3p	CLIP-seq
MIRT2562600	hsa-miR-504	CLIP-seq
MIRT1116342	hsa-miR-513a-5p	CLIP-seq
MIRT2390308	hsa-miR-516b	CLIP-seq
MIRT1116345	hsa-miR-518a-5p	CLIP-seq
MIRT1116352	hsa-miR-527	CLIP-seq
MIRT2263209	hsa-miR-545	CLIP-seq
MIRT2562601	hsa-miR-548ag	CLIP-seq
MIRT2562602	hsa-miR-548ai	CLIP-seq
MIRT2562603	hsa-miR-574-5p	CLIP-seq
MIRT2562604	hsa-miR-642b	CLIP-seq
MIRT2562605	hsa-miR-655	CLIP-seq
MIRT2562607	hsa-miR-663	CLIP-seq
MIRT2562608	hsa-miR-676	CLIP-seq
MIRT2562609	hsa-miR-711	CLIP-seq
MIRT2390309	hsa-miR-875-3p	CLIP-seq
MIRT1116378	hsa-miR-940	CLIP-seq
MIRT1116379	hsa-miR-944	CLIP-seq

Transcription factors

Show/Hide all(4)

Transcription factor	Regulation	Reference
NFYA	Unknown	19553673
NFYB	Unknown	19553673
NFYC	Unknown	19553673
SREBF1	Unknown	19553673

Show/Hide all(26)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003713	Function	Transcription coactivator activity	IBA	21873635
GO:0005515	Function	Protein binding	IPI	32814053
GO:0005634	Component	Nucleus	IBA	21873635
GO:0005634	Component	Nucleus	ISS	11138012
GO:0005635	Component	Nuclear envelope	TAS
GO:0005654	Component	Nucleoplasm	TAS
GO:0005737	Component	Cytoplasm	ISS
GO:0005741	Component	Mitochondrial outer membrane	IBA	21873635
GO:0005789	Component	Endoplasmic reticulum membrane	TAS
GO:0005829	Component	Cytosol	IEA
GO:0006642	Process	Triglyceride mobilization	ISS
GO:0006646	Process	Phosphatidylethanolamine biosynthetic process	TAS
GO:0006656	Process	Phosphatidylcholine biosynthetic process	TAS
GO:0007077	Process	Mitotic nuclear envelope disassembly	TAS
GO:0008195	Function	Phosphatidate phosphatase activity	IBA	21873635
GO:0009062	Process	Fatty acid catabolic process	IBA	21873635
GO:0009062	Process	Fatty acid catabolic process	ISS
GO:0016311	Process	Dephosphorylation	IEA
GO:0019432	Process	Triglyceride biosynthetic process	IBA	21873635
GO:0019432	Process	Triglyceride biosynthetic process	TAS
GO:0031100	Process	Animal organ regeneration	IEA
GO:0031965	Component	Nuclear membrane	ISS
GO:0032869	Process	Cellular response to insulin stimulus	IBA	21873635
GO:0044255	Process	Cellular lipid metabolic process	IBA	21873635
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IBA	21873635
GO:0120162	Process	Positive regulation of cold-induced thermogenesis	ISS	23028044

MIM	HGNC	e!Ensembl
605518	13345	ENSG00000134324

Protein

UniProt ID

Q14693

Protein name

Phosphatidate phosphatase LPIN1 (EC 3.1.3.4) (Lipin-1)

Protein function

Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis and therefore controls the me

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF04571	Lipin_N	1 → 107	lipin, N-terminal conserved region	Family
PF16876	Lipin_mid	464 → 557	Lipin/Ned1/Smp2 multi-domain protein middle domain	Family
PF08235	LNS2	626 → 851	LNS2 (Lipin/Ned1/Smp2)	Domain

Tissue specificity

TISSUE SPECIFICITY: Specifically expressed in skeletal muscle. Also abundant in adipose tissue. Lower levels in some portions of the digestive tract. {ECO:0000269|PubMed:17158099, ECO:0000269|PubMed:22134922}.

Sequence

MNYVGQLAGQVFVTVKELYKGLNPATLSGCIDIIVIRQPNGNLQCSPFHVRFGKMGVLRS
REKVVDIEINGESVDLHMKLGDNGEAFFVQETDNDQEVIPMHLATSPILSEGASRMECQL
KRGSVDRMRGLDPSTPAQVIAPSETPSSSSVVKKRRKRRRKSQLDSLKRDDNMNTSEDED
MFPIEMSSDEAMELLESSRTLPNDIPPFQDDIPEENLSLAVIYPQSASYPNSDREWSPTP
SPSGSRPSTPKSDSELVSKSTERTGQKNPEMLWLWGELPQAAKSSSPHKMKESSPLSSRK
ICDKSHFQAIHSESSDTFSDQSPTLVGGALLDQNKPQTEMQFVNEEDLETLGAAAPLLPM
IEELKPPSASVVQTANKTDSPSRKRDKRSRHLGADGVYLDDLTDMDPEVAALYFPKNGDP
SGLAKHASDNGARSANQSPQSVGSSGVDSGVESTSDGLRDLPSIAISLCGGLSDHREITK
DAFLEQAVSYQQFVDNPAIIDDPNLVVKIGSKYYNWTTAAPLLLAMQAFQKPLPKATVES
IMRDKMPKKGGRWWFSWRGRNTTIKEESKPEQCLAGKAHSTGEQPPQLSLATRVKHESSS
SDEERAAAKPSNAGHLPLLPNVSYKKTLRLTSEQLKSLKLKNGPNDVVFSVTTQYQGTCR
CEGTIYLWNWDDKVIISDIDGTITRSDTLGHILPTLGKDWTHQGIAKLYHKVSQNGYKFL
YCSARAIGMADMTRGYLHWVNERGTVLPQGPLLLSPSSLFSALHREVIEKKPEKFKVQCL
TDIKNLFFPNTEPFYAAFGNRPADVYSYKQVGVSLNRIFTVNPKGELVQEHAKTNISSYV
RLCEVVDHVFPLLKRSHSSDFPCSDTFSNFTFWREPLPPFENQDIHSASA

Sequence length

890

Interactions

View interactions

Show/Hide Unknown Diseases (1)

Disease term	Disease name	Evidence	References	Source
Unknown
Diabetes	Diabetes			GWAS

Show/Hide Text Mining Associations (33)

Disease Name	Relationship Type	References
Associations from Text Mining
Adenocarcinoma of Lung	Stimulate	29659171
Breast Neoplasms	Associate	25834103, 35184130
Carcinoma Hepatocellular	Associate	31162914
Colitis Ulcerative	Associate	39596612
Diabetes Mellitus Type 2	Associate	19543209
Esophageal Achalasia	Associate	34197731
Fatty Liver	Associate	18070763, 28717649
Hepatoblastoma	Associate	19553673
HIV Infections	Inhibit	25063777
Immunologic Deficiency Syndromes	Associate	18070763
Inflammation	Associate	23928362
Insulin Resistance	Associate	17035674, 20530740
Lipid Metabolism Disorders	Associate	23928362
Lipodystrophy	Associate	18070763, 26176221, 28986436
Lipodystrophy Familial Partial	Associate	26176221, 28986436
Lung Neoplasms	Associate	29659171
Metabolic Syndrome	Inhibit	17035674
Metabolic Syndrome	Associate	26276647
Muscular Diseases	Associate	18817903
Myoglobinuria	Associate	18817903, 20583302
Neoplasms	Associate	25834103, 29659171
Neoplasms Adipose Tissue	Associate	19543209
Non alcoholic Fatty Liver Disease	Associate	29732362
Obesity	Inhibit	17035674, 20530740
Obesity	Associate	18070763
Osteoporosis	Associate	36105394
Ovarian Neoplasms	Associate	32096176
Parkinson Disease	Associate	36918862
Prostatic Neoplasms	Stimulate	25834103
Prostatic Neoplasms	Associate	33596934
Renal cell carcinoma 1	Inhibit	23928362
Rhabdomyolysis	Associate	18817903, 20583302, 28986436, 31723421, 32978841, 33514355
Triple Negative Breast Neoplasms	Associate	28474731

LPIN1 (lipin 1)