IL17RC (interleukin 17 receptor C)

Gene
Gene SNPs Other IDs
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
84818
Gene name Gene Name - the full gene name approved by the HGNC.
Interleukin 17 receptor C
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
IL17RC
Synonyms (NCBI Gene) Gene synonyms aliases
CANDF9, IL17-RL, IL17RL
Disease Acronyms (UniProt) Disease acronyms from UniProt database
CANDF9
Chromosome Chromosome number
3
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
3p25.3|3p25.3-p24.1
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is
SNPs SNP information provided by dbSNP.
Gene SNPs Other IDs
Show/Hide all(3)
SNP ID Visualize variation Clinical significance Consequence
rs559955121 C>T Likely-pathogenic Coding sequence variant, stop gained, non coding transcript variant
rs773852926 C>T Pathogenic Non coding transcript variant, coding sequence variant, stop gained
rs1057518751 C>T Pathogenic Stop gained, non coding transcript variant, coding sequence variant
miRNA miRNA information provided by mirtarbase database.
Gene SNPs Other IDs
Show/Hide all(5)
miRTarBase ID miRNA Experiments Reference
MIRT028962 hsa-miR-26b-5p Microarray 19088304
MIRT052327 hsa-let-7b-5p CLASH 23622248
MIRT050548 hsa-miR-20a-5p CLASH 23622248
MIRT036625 hsa-miR-940 CLASH 23622248
MIRT036625 hsa-miR-940 CLASH 23622248
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene SNPs Other IDs
Show/Hide all(13)
GO ID Ontology Definition Evidence Reference
GO:0005102 Function Signaling receptor binding IEA
GO:0005515 Function Protein binding IPI 24120361, 28827714
GO:0005886 Component Plasma membrane TAS
GO:0006954 Process Inflammatory response IEA
GO:0009986 Component Cell surface IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene SNPs Other IDs
MIM HGNC e!Ensembl
610925 18358 ENSG00000163702
Protein
Gene SNPs Other IDs
UniProt ID Q8NAC3
Protein name Interleukin-17 receptor C (IL-17 receptor C) (IL-17RC) (Interleukin-17 receptor homolog) (IL17Rhom) (Interleukin-17 receptor-like protein) (IL-17RL) (ZcytoR14)
Protein function Receptor for IL17A and IL17F, major effector cytokines of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tissue integrity (By similarity). Receptor for IL17A and IL17F, major effector cytokines of inn
PDB 6HG4 , 6HG9 , 6HGA , 7UWN , 7ZAN
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF15037 IL17_R_N 142 → 530 Interleukin-17 receptor extracellular region Family
PF08357 SEFIR 584 → 737 SEFIR domain Family
Tissue specificity TISSUE SPECIFICITY: Expressed in prostate, skeletal muscle, kidney and placenta (at protein level) (PubMed:11706037). Expressed in brain, cartilage, colon, heart, intestine, kidney, liver, lung, muscle, placenta, and prostate (PubMed:11706037). Also detec
Sequence
Sequence length 791
Interactions View interactions