IFNA17 (interferon alpha 17)

Gene
Gene SNPs Other IDs Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
3451
Gene name Gene Name - the full gene name approved by the HGNC.
Interferon alpha 17
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
IFNA17
Synonyms (NCBI Gene) Gene synonyms aliases
IFN-alphaI, IFNA, INFA, LEIF2C1
Chromosome Chromosome number
9
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
9p21.3
miRNA miRNA information provided by mirtarbase database.
Gene SNPs Other IDs Associated diseases
Show/Hide all(2)
miRTarBase ID miRNA Experiments Reference
MIRT1060628 hsa-miR-3121-3p CLIP-seq
MIRT1060629 hsa-miR-3913-3p CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene SNPs Other IDs Associated diseases
Show/Hide all(21)
GO ID Ontology Definition Evidence Reference
GO:0002250 Process Adaptive immune response IBA
GO:0002286 Process T cell activation involved in immune response IBA
GO:0002312 Process B cell activation involved in immune response IBA
GO:0002323 Process Natural killer cell activation involved in immune response IBA
GO:0005125 Function Cytokine activity IBA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene SNPs Other IDs Associated diseases
MIM HGNC e!Ensembl
147583 5422 ENSG00000234829
Protein
Gene SNPs Other IDs Associated diseases
UniProt ID P01571
Protein name Interferon alpha-17 (IFN-alpha-17) (Interferon alpha-88) (Interferon alpha-I') (LeIF I) (Interferon alpha-T)
Protein function Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00143 Interferon 26 → 185 Interferon alpha/beta domain Domain
Sequence
Sequence length 189
Interactions View interactions
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Gene SNPs Other IDs Associated diseases
Show/Hide Unknown Diseases (1)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Systemic lupus erythematosus Systemic lupus erythematosus N/A N/A GWAS
Show/Hide Text Mining Associations (13)
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Brain Neoplasms Associate 31729458
Carcinoma Intraductal Noninfiltrating Associate 38615592
Erdheim Chester Disease Inhibit 37335698
Hereditary Breast and Ovarian Cancer Syndrome Stimulate 38615592
Infections Stimulate 38101522
Inflammation Associate 26202481, 29800615, 30536330, 37232357
Leukemia Associate 9219533
Neoplasms Associate 32431053, 8751858
Nevus Epithelioid and Spindle Cell Associate 32431053
Prostatic Neoplasms Stimulate 20808670