ICAM1 (intercellular adhesion molecule 1)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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3383 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Intercellular adhesion molecule 1 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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ICAM1 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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BB2, CD54, P3.58 |
Chromosome
Chromosome number
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19 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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19p13.2 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by Ref |
SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Transcription factors | |||||||||||||||||||
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | P05362 | ||||||||||
Protein name | Intercellular adhesion molecule 1 (ICAM-1) (Major group rhinovirus receptor) (CD antigen CD54) | ||||||||||
Protein function | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activati | ||||||||||
PDB | 1D3E , 1D3I , 1D3L , 1IAM , 1IC1 , 1MQ8 , 1P53 , 1Z7Z , 2OZ4 , 3TCX , 5MZA , 6EIT , 6S8U , 7BG7 | ||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 532 | ||||||||||
Interactions | View interactions |