GNAI3 (G protein subunit alpha i3)
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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2773 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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G protein subunit alpha i3 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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GNAI3 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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87U6, ARCND1, ARCODS, HG1A |
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Chromosome
Chromosome number
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1 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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1p13.3 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling pathways. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes an alpha subunit and belongs to the G-alph |
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SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | P08754 | ||||||||||
| Protein name | Guanine nucleotide-binding protein G(i) subunit alpha-3 (G(i) alpha-3) | ||||||||||
| Protein function | Heterotrimeric guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates | ||||||||||
| PDB | 2IHB , 2ODE , 2V4Z , 4G5O , 4G5R , 4G5S , 7E9H , 7KH0 , 7RA3 , 7RGP , 7T10 , 7T11 , 7X6I , 8GVX , 8JD6 , 8K9L , 8OY1 , 8SZH , 8SZI , 8WGB , 9AVL | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 354 | ||||||||||
| Interactions | View interactions | ||||||||||
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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