Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
2524
Gene name Gene Name - the full gene name approved by the HGNC.
Fucosyltransferase 2 (H blood group)
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
FUT2
Synonyms (NCBI Gene) Gene synonyms aliases
B12QTL1, SE, SEC2, Se2, sej
Chromosome Chromosome number
19
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
19q13.33
Summary Summary of gene provided in NCBI Entrez Gene.
The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the soluble A and B antigen synthesis pathway. This gene is one of two encoding th
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT437485 hsa-miR-15b-5p Luciferase reporter assay, qRT-PCR, Western blot 24122375
MIRT690897 hsa-miR-21-3p HITS-CLIP 23313552
MIRT690896 hsa-miR-3591-3p HITS-CLIP 23313552
MIRT690895 hsa-miR-383-3p HITS-CLIP 23313552
MIRT690894 hsa-miR-5693 HITS-CLIP 23313552
Transcription factors
Transcription factor Regulation Reference
CDX2 Activation 22547830
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0001936 Process Regulation of endothelial cell proliferation ISS
GO:0005515 Function Protein binding IPI 32814053
GO:0005794 Component Golgi apparatus TAS 11698403
GO:0005975 Process Carbohydrate metabolic process TAS 7876235
GO:0006486 Process Protein glycosylation IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
182100 4013 ENSG00000176920
Protein
UniProt ID Q10981
Protein name Galactoside alpha-(1,2)-fucosyltransferase 2 (Alpha(1,2)FT 2) (Fucosyltransferase 2) (GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 2) (SE2) (Secretor blood group alpha-2-fucosyltransferase) (Secretor factor) (Se) (Type 1 galactoside alpha-
Protein function Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the terminal galactose on both O- and N-linked glycans chains of cell surface glycoproteins and glycolipids and the resulting epitope regulates several processes
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01531 Glyco_transf_11 21 334 Glycosyl transferase family 11 Family
Tissue specificity TISSUE SPECIFICITY: Small intestine, colon and lung.
Sequence
Sequence length 343
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Unknown
Disease term Disease name Evidence References Source
Psoriasis Psoriasis GWAS
Diabetes Diabetes GWAS
Crohn Disease Crohn Disease GWAS
Multiple Sclerosis Multiple Sclerosis GWAS
Associations from Text Mining
Disease Name Relationship Type References
Acute Disease Associate 26643031
Anemia Megaloblastic Associate 39350204
Asthma Associate 33328473
Autism Spectrum Disorder Associate 31595719
Autoimmune Diseases Associate 22025780, 29182645
Bacteremia Associate 26643031
Behcet Syndrome Associate 28166214
Blood Coagulation Disorders Associate 37085521
Bronchiolitis Associate 30376117
Caliciviridae Infections Associate 16306606, 25744498, 27284939, 32448707, 36121297