Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs Transcription factors Other IDs Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	2194
Gene name Gene Name - the full gene name approved by the HGNC.	Fatty acid synthase
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	FASN
Synonyms (NCBI Gene) Gene synonyms aliases	FAS, OA-519, SDR27X1
Chromosome Chromosome number	17
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	17q25.3
Summary Summary of gene provided in NCBI Entrez Gene.	The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this pro

Show/Hide all(1)

SNP ID	Visualize variation	Clinical significance	Consequence
rs145515446	G>A	Conflicting-interpretations-of-pathogenicity	Coding sequence variant, missense variant

Show/Hide all(540)

miRTarBase ID	miRNA	Experiments	Reference
MIRT051341	hsa-miR-15a-5p	CLASH	23622248
MIRT050921	hsa-miR-17-5p	CLASH	23622248
MIRT050182	hsa-miR-26a-5p	CLASH	23622248
MIRT049363	hsa-miR-92a-3p	CLASH	23622248
MIRT048815	hsa-miR-93-5p	CLASH	23622248
MIRT048070	hsa-miR-197-3p	CLASH	23622248
MIRT047715	hsa-miR-10a-5p	CLASH	23622248
MIRT047454	hsa-miR-10b-5p	CLASH	23622248
MIRT046667	hsa-miR-222-3p	CLASH	23622248
MIRT046177	hsa-miR-27b-3p	CLASH	23622248
MIRT046177	hsa-miR-27b-3p	CLASH	23622248
MIRT044920	hsa-miR-186-5p	CLASH	23622248
MIRT044920	hsa-miR-186-5p	CLASH	23622248
MIRT043627	hsa-miR-326	CLASH	23622248
MIRT043627	hsa-miR-326	CLASH	23622248
MIRT043370	hsa-miR-331-3p	CLASH	23622248
MIRT042890	hsa-miR-324-3p	CLASH	23622248
MIRT042639	hsa-miR-423-3p	CLASH	23622248
MIRT041844	hsa-miR-484	CLASH	23622248
MIRT041844	hsa-miR-484	CLASH	23622248
MIRT041844	hsa-miR-484	CLASH	23622248
MIRT041844	hsa-miR-484	CLASH	23622248
MIRT041844	hsa-miR-484	CLASH	23622248
MIRT041353	hsa-miR-193b-3p	CLASH	23622248
MIRT041353	hsa-miR-193b-3p	CLASH	23622248
MIRT040657	hsa-miR-92b-3p	CLASH	23622248
MIRT039824	hsa-miR-615-3p	CLASH	23622248
MIRT039824	hsa-miR-615-3p	CLASH	23622248
MIRT039824	hsa-miR-615-3p	CLASH	23622248
MIRT039824	hsa-miR-615-3p	CLASH	23622248
MIRT038318	hsa-miR-130b-5p	CLASH	23622248
MIRT037647	hsa-miR-744-5p	CLASH	23622248
MIRT037647	hsa-miR-744-5p	CLASH	23622248
MIRT036832	hsa-miR-877-3p	CLASH	23622248
MIRT036557	hsa-miR-942-5p	CLASH	23622248
MIRT035891	hsa-miR-1303	CLASH	23622248
MIRT035847	hsa-miR-1268a	CLASH	23622248
MIRT035759	hsa-miR-2110	CLASH	23622248
MIRT053106	hsa-miR-424-5p	Luciferase reporter assay, Western blot	23599729
MIRT053228	hsa-miR-195-5p	Luciferase reporter assay, qRT-PCR, Western blot	23162665
MIRT054707	hsa-miR-1-3p	qRT-PCR, Western blot	24310399
MIRT658284	hsa-miR-6771-3p	HITS-CLIP	23824327
MIRT658283	hsa-miR-1264	HITS-CLIP	23824327
MIRT658282	hsa-miR-6861-5p	HITS-CLIP	23824327
MIRT658281	hsa-miR-6776-5p	HITS-CLIP	23824327
MIRT658280	hsa-miR-3182	HITS-CLIP	23824327
MIRT658279	hsa-miR-6740-3p	HITS-CLIP	23824327
MIRT658278	hsa-miR-4314	HITS-CLIP	23824327
MIRT658277	hsa-miR-4774-3p	HITS-CLIP	23824327
MIRT548285	hsa-miR-497-5p	PAR-CLIP	20371350
MIRT548284	hsa-miR-6838-5p	PAR-CLIP	20371350
MIRT548283	hsa-miR-16-5p	PAR-CLIP	20371350
MIRT548282	hsa-miR-15b-5p	PAR-CLIP	20371350
MIRT053106	hsa-miR-424-5p	PAR-CLIP	20371350
MIRT051341	hsa-miR-15a-5p	PAR-CLIP	20371350
MIRT053228	hsa-miR-195-5p	PAR-CLIP	20371350
MIRT548281	hsa-miR-4668-3p	PAR-CLIP	20371350
MIRT548280	hsa-miR-15b-3p	PAR-CLIP	20371350
MIRT548285	hsa-miR-497-5p	PAR-CLIP	20371350
MIRT548284	hsa-miR-6838-5p	PAR-CLIP	20371350
MIRT548283	hsa-miR-16-5p	PAR-CLIP	20371350
MIRT548282	hsa-miR-15b-5p	PAR-CLIP	20371350
MIRT053106	hsa-miR-424-5p	PAR-CLIP	20371350
MIRT051341	hsa-miR-15a-5p	PAR-CLIP	20371350
MIRT053228	hsa-miR-195-5p	PAR-CLIP	20371350
MIRT548281	hsa-miR-4668-3p	PAR-CLIP	20371350
MIRT548280	hsa-miR-15b-3p	PAR-CLIP	20371350
MIRT548285	hsa-miR-497-5p	PAR-CLIP	21572407
MIRT548284	hsa-miR-6838-5p	PAR-CLIP	21572407
MIRT548283	hsa-miR-16-5p	PAR-CLIP	21572407
MIRT548282	hsa-miR-15b-5p	PAR-CLIP	21572407
MIRT053106	hsa-miR-424-5p	PAR-CLIP	21572407
MIRT051341	hsa-miR-15a-5p	PAR-CLIP	21572407
MIRT053228	hsa-miR-195-5p	PAR-CLIP	21572407
MIRT548281	hsa-miR-4668-3p	PAR-CLIP	21572407
MIRT548280	hsa-miR-15b-3p	PAR-CLIP	21572407
MIRT756169	hsa-miR-532-5p	qRT-PCR, Western blot	25983556
MIRT047715	hsa-miR-10a-5p	Luciferase reporter assay, Western blotting, qRT-PCR	33128541
MIRT735807	hsa-miR-27a-3p	Luciferase reporter assay, Western blotting, qRT-PCR	32975270
MIRT658284	hsa-miR-6771-3p	HITS-CLIP	23824327
MIRT658283	hsa-miR-1264	HITS-CLIP	23824327
MIRT658282	hsa-miR-6861-5p	HITS-CLIP	23824327
MIRT658281	hsa-miR-6776-5p	HITS-CLIP	23824327
MIRT658280	hsa-miR-3182	HITS-CLIP	23824327
MIRT658279	hsa-miR-6740-3p	HITS-CLIP	23824327
MIRT658278	hsa-miR-4314	HITS-CLIP	23824327
MIRT658277	hsa-miR-4774-3p	HITS-CLIP	23824327
MIRT548285	hsa-miR-497-5p	PAR-CLIP	20371350
MIRT548284	hsa-miR-6838-5p	PAR-CLIP	20371350
MIRT548283	hsa-miR-16-5p	PAR-CLIP	20371350
MIRT548282	hsa-miR-15b-5p	PAR-CLIP	20371350
MIRT053106	hsa-miR-424-5p	PAR-CLIP	20371350
MIRT051341	hsa-miR-15a-5p	PAR-CLIP	20371350
MIRT053228	hsa-miR-195-5p	PAR-CLIP	20371350
MIRT548281	hsa-miR-4668-3p	PAR-CLIP	20371350
MIRT548280	hsa-miR-15b-3p	PAR-CLIP	20371350
MIRT548285	hsa-miR-497-5p	PAR-CLIP	20371350
MIRT548284	hsa-miR-6838-5p	PAR-CLIP	20371350
MIRT548283	hsa-miR-16-5p	PAR-CLIP	20371350
MIRT548282	hsa-miR-15b-5p	PAR-CLIP	20371350
MIRT053106	hsa-miR-424-5p	PAR-CLIP	20371350
MIRT051341	hsa-miR-15a-5p	PAR-CLIP	20371350
MIRT053228	hsa-miR-195-5p	PAR-CLIP	20371350
MIRT548281	hsa-miR-4668-3p	PAR-CLIP	20371350
MIRT548280	hsa-miR-15b-3p	PAR-CLIP	20371350
MIRT548285	hsa-miR-497-5p	PAR-CLIP	21572407
MIRT548284	hsa-miR-6838-5p	PAR-CLIP	21572407
MIRT548283	hsa-miR-16-5p	PAR-CLIP	21572407
MIRT548282	hsa-miR-15b-5p	PAR-CLIP	21572407
MIRT053106	hsa-miR-424-5p	PAR-CLIP	21572407
MIRT051341	hsa-miR-15a-5p	PAR-CLIP	21572407
MIRT053228	hsa-miR-195-5p	PAR-CLIP	21572407
MIRT548281	hsa-miR-4668-3p	PAR-CLIP	21572407
MIRT548280	hsa-miR-15b-3p	PAR-CLIP	21572407
MIRT756169	hsa-miR-532-5p	Luciferase reporter assay, Immunoprecipitaion (IP)	35499057
MIRT548285	hsa-miR-497-5p	Luciferase reporter assay, Western blotting, qRT-PCR	34789312
MIRT548285	hsa-miR-497-5p	Luciferase reporter assay, Western blotting, qRT-PCR	34789312
MIRT989500	hsa-miR-101	CLIP-seq
MIRT989501	hsa-miR-103a	CLIP-seq
MIRT989502	hsa-miR-107	CLIP-seq
MIRT989503	hsa-miR-1207-5p	CLIP-seq
MIRT989504	hsa-miR-1224-3p	CLIP-seq
MIRT989505	hsa-miR-1260	CLIP-seq
MIRT989506	hsa-miR-1260b	CLIP-seq
MIRT989507	hsa-miR-1270	CLIP-seq
MIRT989508	hsa-miR-1280	CLIP-seq
MIRT989509	hsa-miR-1286	CLIP-seq
MIRT989510	hsa-miR-1293	CLIP-seq
MIRT989511	hsa-miR-1302	CLIP-seq
MIRT989512	hsa-miR-144	CLIP-seq
MIRT989513	hsa-miR-147b	CLIP-seq
MIRT989514	hsa-miR-1539	CLIP-seq
MIRT989515	hsa-miR-15a	CLIP-seq
MIRT989516	hsa-miR-15b	CLIP-seq
MIRT989517	hsa-miR-16	CLIP-seq
MIRT989518	hsa-miR-195	CLIP-seq
MIRT989519	hsa-miR-198	CLIP-seq
MIRT989520	hsa-miR-2278	CLIP-seq
MIRT989521	hsa-miR-3065-3p	CLIP-seq
MIRT989522	hsa-miR-3074-5p	CLIP-seq
MIRT989523	hsa-miR-3136-3p	CLIP-seq
MIRT989524	hsa-miR-3138	CLIP-seq
MIRT989525	hsa-miR-3150b-3p	CLIP-seq
MIRT989526	hsa-miR-3177-5p	CLIP-seq
MIRT989527	hsa-miR-3193	CLIP-seq
MIRT989528	hsa-miR-3195	CLIP-seq
MIRT989529	hsa-miR-34a	CLIP-seq
MIRT989530	hsa-miR-34c-5p	CLIP-seq
MIRT989531	hsa-miR-3591-3p	CLIP-seq
MIRT989532	hsa-miR-3656	CLIP-seq
MIRT989533	hsa-miR-3657	CLIP-seq
MIRT989534	hsa-miR-3660	CLIP-seq
MIRT989535	hsa-miR-3687	CLIP-seq
MIRT989536	hsa-miR-3689a-3p	CLIP-seq
MIRT989537	hsa-miR-3689c	CLIP-seq
MIRT989538	hsa-miR-3908	CLIP-seq
MIRT989539	hsa-miR-3929	CLIP-seq
MIRT989540	hsa-miR-3945	CLIP-seq
MIRT989541	hsa-miR-3960	CLIP-seq
MIRT989542	hsa-miR-424	CLIP-seq
MIRT989543	hsa-miR-4265	CLIP-seq
MIRT989544	hsa-miR-4286	CLIP-seq
MIRT989545	hsa-miR-4294	CLIP-seq
MIRT989546	hsa-miR-4296	CLIP-seq
MIRT989547	hsa-miR-4298	CLIP-seq
MIRT989548	hsa-miR-4299	CLIP-seq
MIRT989549	hsa-miR-4310	CLIP-seq
MIRT989550	hsa-miR-4322	CLIP-seq
MIRT989551	hsa-miR-4419b	CLIP-seq
MIRT989552	hsa-miR-4436b-3p	CLIP-seq
MIRT989553	hsa-miR-4442	CLIP-seq
MIRT989554	hsa-miR-4455	CLIP-seq
MIRT989555	hsa-miR-4456	CLIP-seq
MIRT989556	hsa-miR-4467	CLIP-seq
MIRT989557	hsa-miR-4478	CLIP-seq
MIRT989558	hsa-miR-4483	CLIP-seq
MIRT989559	hsa-miR-4488	CLIP-seq
MIRT989560	hsa-miR-449a	CLIP-seq
MIRT989561	hsa-miR-449b	CLIP-seq
MIRT989562	hsa-miR-4520a-3p	CLIP-seq
MIRT989563	hsa-miR-4524	CLIP-seq
MIRT989564	hsa-miR-4526	CLIP-seq
MIRT989565	hsa-miR-4635	CLIP-seq
MIRT989566	hsa-miR-4645-3p	CLIP-seq
MIRT989567	hsa-miR-4648	CLIP-seq
MIRT989568	hsa-miR-4650-5p	CLIP-seq
MIRT989569	hsa-miR-4653-3p	CLIP-seq
MIRT989570	hsa-miR-4654	CLIP-seq
MIRT989571	hsa-miR-4660	CLIP-seq
MIRT989572	hsa-miR-4683	CLIP-seq
MIRT989573	hsa-miR-4684-5p	CLIP-seq
MIRT989574	hsa-miR-4687-3p	CLIP-seq
MIRT989575	hsa-miR-4689	CLIP-seq
MIRT989576	hsa-miR-4690-3p	CLIP-seq
MIRT989577	hsa-miR-4697-5p	CLIP-seq
MIRT989578	hsa-miR-4698	CLIP-seq
MIRT989579	hsa-miR-4706	CLIP-seq
MIRT989580	hsa-miR-4717-3p	CLIP-seq
MIRT989581	hsa-miR-4728-5p	CLIP-seq
MIRT989582	hsa-miR-4734	CLIP-seq
MIRT989583	hsa-miR-4736	CLIP-seq
MIRT989584	hsa-miR-4743	CLIP-seq
MIRT989585	hsa-miR-4749-5p	CLIP-seq
MIRT989586	hsa-miR-4763-3p	CLIP-seq
MIRT989587	hsa-miR-4767	CLIP-seq
MIRT989588	hsa-miR-4769-5p	CLIP-seq
MIRT989589	hsa-miR-4784	CLIP-seq
MIRT989590	hsa-miR-4787-5p	CLIP-seq
MIRT989591	hsa-miR-4802-3p	CLIP-seq
MIRT989592	hsa-miR-485-5p	CLIP-seq
MIRT989593	hsa-miR-495	CLIP-seq
MIRT989594	hsa-miR-497	CLIP-seq
MIRT989595	hsa-miR-503	CLIP-seq
MIRT989596	hsa-miR-512-5p	CLIP-seq
MIRT989597	hsa-miR-513a-3p	CLIP-seq
MIRT989598	hsa-miR-526b	CLIP-seq
MIRT989599	hsa-miR-544b	CLIP-seq
MIRT989600	hsa-miR-548q	CLIP-seq
MIRT989601	hsa-miR-564	CLIP-seq
MIRT989602	hsa-miR-571	CLIP-seq
MIRT989603	hsa-miR-578	CLIP-seq
MIRT989604	hsa-miR-582-5p	CLIP-seq
MIRT989605	hsa-miR-607	CLIP-seq
MIRT989606	hsa-miR-609	CLIP-seq
MIRT989607	hsa-miR-615-5p	CLIP-seq
MIRT989608	hsa-miR-620	CLIP-seq
MIRT989609	hsa-miR-634	CLIP-seq
MIRT989610	hsa-miR-637	CLIP-seq
MIRT989611	hsa-miR-646	CLIP-seq
MIRT989612	hsa-miR-661	CLIP-seq
MIRT989613	hsa-miR-711	CLIP-seq
MIRT989614	hsa-miR-744	CLIP-seq
MIRT989615	hsa-miR-759	CLIP-seq
MIRT989616	hsa-miR-924	CLIP-seq
MIRT989617	hsa-miR-935	CLIP-seq
MIRT989500	hsa-miR-101	CLIP-seq
MIRT989501	hsa-miR-103a	CLIP-seq
MIRT989502	hsa-miR-107	CLIP-seq
MIRT989503	hsa-miR-1207-5p	CLIP-seq
MIRT989504	hsa-miR-1224-3p	CLIP-seq
MIRT989505	hsa-miR-1260	CLIP-seq
MIRT989506	hsa-miR-1260b	CLIP-seq
MIRT1993284	hsa-miR-1262	CLIP-seq
MIRT989507	hsa-miR-1270	CLIP-seq
MIRT989508	hsa-miR-1280	CLIP-seq
MIRT989509	hsa-miR-1286	CLIP-seq
MIRT1993285	hsa-miR-1291	CLIP-seq
MIRT989510	hsa-miR-1293	CLIP-seq
MIRT989511	hsa-miR-1302	CLIP-seq
MIRT989512	hsa-miR-144	CLIP-seq
MIRT1993286	hsa-miR-146b-3p	CLIP-seq
MIRT989515	hsa-miR-15a	CLIP-seq
MIRT989516	hsa-miR-15b	CLIP-seq
MIRT989517	hsa-miR-16	CLIP-seq
MIRT1993287	hsa-miR-1908	CLIP-seq
MIRT1993288	hsa-miR-1909	CLIP-seq
MIRT1993289	hsa-miR-1914	CLIP-seq
MIRT989518	hsa-miR-195	CLIP-seq
MIRT989519	hsa-miR-198	CLIP-seq
MIRT1993290	hsa-miR-214	CLIP-seq
MIRT989520	hsa-miR-2278	CLIP-seq
MIRT1993291	hsa-miR-27a	CLIP-seq
MIRT1993292	hsa-miR-27b	CLIP-seq
MIRT989524	hsa-miR-3138	CLIP-seq
MIRT989525	hsa-miR-3150b-3p	CLIP-seq
MIRT989526	hsa-miR-3177-5p	CLIP-seq
MIRT1993293	hsa-miR-342-5p	CLIP-seq
MIRT989529	hsa-miR-34a	CLIP-seq
MIRT989530	hsa-miR-34c-5p	CLIP-seq
MIRT989531	hsa-miR-3591-3p	CLIP-seq
MIRT1993294	hsa-miR-3619-5p	CLIP-seq
MIRT1993295	hsa-miR-3646	CLIP-seq
MIRT989532	hsa-miR-3656	CLIP-seq
MIRT989533	hsa-miR-3657	CLIP-seq
MIRT989534	hsa-miR-3660	CLIP-seq
MIRT1993296	hsa-miR-3662	CLIP-seq
MIRT989535	hsa-miR-3687	CLIP-seq
MIRT989536	hsa-miR-3689a-3p	CLIP-seq
MIRT989537	hsa-miR-3689c	CLIP-seq
MIRT1993297	hsa-miR-3691-3p	CLIP-seq
MIRT989538	hsa-miR-3908	CLIP-seq
MIRT989539	hsa-miR-3929	CLIP-seq
MIRT1993298	hsa-miR-3944-5p	CLIP-seq
MIRT989541	hsa-miR-3960	CLIP-seq
MIRT1993299	hsa-miR-412	CLIP-seq
MIRT989542	hsa-miR-424	CLIP-seq
MIRT989543	hsa-miR-4265	CLIP-seq
MIRT989545	hsa-miR-4294	CLIP-seq
MIRT989546	hsa-miR-4296	CLIP-seq
MIRT989547	hsa-miR-4298	CLIP-seq
MIRT989548	hsa-miR-4299	CLIP-seq
MIRT989549	hsa-miR-4310	CLIP-seq
MIRT989550	hsa-miR-4322	CLIP-seq
MIRT989551	hsa-miR-4419b	CLIP-seq
MIRT1993300	hsa-miR-4433	CLIP-seq
MIRT989553	hsa-miR-4442	CLIP-seq
MIRT989554	hsa-miR-4455	CLIP-seq
MIRT989555	hsa-miR-4456	CLIP-seq
MIRT989556	hsa-miR-4467	CLIP-seq
MIRT989557	hsa-miR-4478	CLIP-seq
MIRT989558	hsa-miR-4483	CLIP-seq
MIRT989559	hsa-miR-4488	CLIP-seq
MIRT989560	hsa-miR-449a	CLIP-seq
MIRT989561	hsa-miR-449b	CLIP-seq
MIRT989562	hsa-miR-4520a-3p	CLIP-seq
MIRT989563	hsa-miR-4524	CLIP-seq
MIRT989564	hsa-miR-4526	CLIP-seq
MIRT1993301	hsa-miR-4530	CLIP-seq
MIRT989565	hsa-miR-4635	CLIP-seq
MIRT989566	hsa-miR-4645-3p	CLIP-seq
MIRT989567	hsa-miR-4648	CLIP-seq
MIRT989568	hsa-miR-4650-5p	CLIP-seq
MIRT1993302	hsa-miR-4651	CLIP-seq
MIRT989570	hsa-miR-4654	CLIP-seq
MIRT989571	hsa-miR-4660	CLIP-seq
MIRT1993303	hsa-miR-4664-5p	CLIP-seq
MIRT989572	hsa-miR-4683	CLIP-seq
MIRT989573	hsa-miR-4684-5p	CLIP-seq
MIRT989575	hsa-miR-4689	CLIP-seq
MIRT1993304	hsa-miR-4690-5p	CLIP-seq
MIRT989577	hsa-miR-4697-5p	CLIP-seq
MIRT989578	hsa-miR-4698	CLIP-seq
MIRT1993305	hsa-miR-4701-3p	CLIP-seq
MIRT1993306	hsa-miR-4707-3p	CLIP-seq
MIRT989580	hsa-miR-4717-3p	CLIP-seq
MIRT989581	hsa-miR-4728-5p	CLIP-seq
MIRT989583	hsa-miR-4736	CLIP-seq
MIRT989584	hsa-miR-4743	CLIP-seq
MIRT989586	hsa-miR-4763-3p	CLIP-seq
MIRT989588	hsa-miR-4769-5p	CLIP-seq
MIRT989589	hsa-miR-4784	CLIP-seq
MIRT989590	hsa-miR-4787-5p	CLIP-seq
MIRT989592	hsa-miR-485-5p	CLIP-seq
MIRT989593	hsa-miR-495	CLIP-seq
MIRT989594	hsa-miR-497	CLIP-seq
MIRT989595	hsa-miR-503	CLIP-seq
MIRT989597	hsa-miR-513a-3p	CLIP-seq
MIRT1993307	hsa-miR-513a-5p	CLIP-seq
MIRT1993308	hsa-miR-515-5p	CLIP-seq
MIRT989598	hsa-miR-526b	CLIP-seq
MIRT1993309	hsa-miR-542-5p	CLIP-seq
MIRT989599	hsa-miR-544b	CLIP-seq
MIRT1993310	hsa-miR-548c-3p	CLIP-seq
MIRT989600	hsa-miR-548q	CLIP-seq
MIRT1993311	hsa-miR-550a	CLIP-seq
MIRT989603	hsa-miR-578	CLIP-seq
MIRT989604	hsa-miR-582-5p	CLIP-seq
MIRT1993312	hsa-miR-604	CLIP-seq
MIRT989605	hsa-miR-607	CLIP-seq
MIRT1993313	hsa-miR-608	CLIP-seq
MIRT989606	hsa-miR-609	CLIP-seq
MIRT989607	hsa-miR-615-5p	CLIP-seq
MIRT989608	hsa-miR-620	CLIP-seq
MIRT989609	hsa-miR-634	CLIP-seq
MIRT989610	hsa-miR-637	CLIP-seq
MIRT1993314	hsa-miR-644	CLIP-seq
MIRT989611	hsa-miR-646	CLIP-seq
MIRT1993315	hsa-miR-647	CLIP-seq
MIRT989612	hsa-miR-661	CLIP-seq
MIRT1993316	hsa-miR-663	CLIP-seq
MIRT1993317	hsa-miR-663b	CLIP-seq
MIRT1993318	hsa-miR-665	CLIP-seq
MIRT989613	hsa-miR-711	CLIP-seq
MIRT989615	hsa-miR-759	CLIP-seq
MIRT1993319	hsa-miR-761	CLIP-seq
MIRT989616	hsa-miR-924	CLIP-seq
MIRT989617	hsa-miR-935	CLIP-seq
MIRT989500	hsa-miR-101	CLIP-seq
MIRT989501	hsa-miR-103a	CLIP-seq
MIRT989502	hsa-miR-107	CLIP-seq
MIRT989503	hsa-miR-1207-5p	CLIP-seq
MIRT989504	hsa-miR-1224-3p	CLIP-seq
MIRT989505	hsa-miR-1260	CLIP-seq
MIRT989506	hsa-miR-1260b	CLIP-seq
MIRT1993284	hsa-miR-1262	CLIP-seq
MIRT989508	hsa-miR-1280	CLIP-seq
MIRT989509	hsa-miR-1286	CLIP-seq
MIRT989510	hsa-miR-1293	CLIP-seq
MIRT989511	hsa-miR-1302	CLIP-seq
MIRT989512	hsa-miR-144	CLIP-seq
MIRT989514	hsa-miR-1539	CLIP-seq
MIRT989515	hsa-miR-15a	CLIP-seq
MIRT989516	hsa-miR-15b	CLIP-seq
MIRT989517	hsa-miR-16	CLIP-seq
MIRT1993287	hsa-miR-1908	CLIP-seq
MIRT1993288	hsa-miR-1909	CLIP-seq
MIRT1993289	hsa-miR-1914	CLIP-seq
MIRT989518	hsa-miR-195	CLIP-seq
MIRT989519	hsa-miR-198	CLIP-seq
MIRT1993290	hsa-miR-214	CLIP-seq
MIRT989520	hsa-miR-2278	CLIP-seq
MIRT1993291	hsa-miR-27a	CLIP-seq
MIRT1993292	hsa-miR-27b	CLIP-seq
MIRT989521	hsa-miR-3065-3p	CLIP-seq
MIRT989522	hsa-miR-3074-5p	CLIP-seq
MIRT989524	hsa-miR-3138	CLIP-seq
MIRT989525	hsa-miR-3150b-3p	CLIP-seq
MIRT989526	hsa-miR-3177-5p	CLIP-seq
MIRT989527	hsa-miR-3193	CLIP-seq
MIRT989528	hsa-miR-3195	CLIP-seq
MIRT1993293	hsa-miR-342-5p	CLIP-seq
MIRT989531	hsa-miR-3591-3p	CLIP-seq
MIRT1993294	hsa-miR-3619-5p	CLIP-seq
MIRT1993295	hsa-miR-3646	CLIP-seq
MIRT989532	hsa-miR-3656	CLIP-seq
MIRT989534	hsa-miR-3660	CLIP-seq
MIRT1993296	hsa-miR-3662	CLIP-seq
MIRT989535	hsa-miR-3687	CLIP-seq
MIRT989536	hsa-miR-3689a-3p	CLIP-seq
MIRT989537	hsa-miR-3689c	CLIP-seq
MIRT989538	hsa-miR-3908	CLIP-seq
MIRT989539	hsa-miR-3929	CLIP-seq
MIRT1993298	hsa-miR-3944-5p	CLIP-seq
MIRT989540	hsa-miR-3945	CLIP-seq
MIRT989541	hsa-miR-3960	CLIP-seq
MIRT1993299	hsa-miR-412	CLIP-seq
MIRT989542	hsa-miR-424	CLIP-seq
MIRT989543	hsa-miR-4265	CLIP-seq
MIRT989545	hsa-miR-4294	CLIP-seq
MIRT989546	hsa-miR-4296	CLIP-seq
MIRT989547	hsa-miR-4298	CLIP-seq
MIRT989549	hsa-miR-4310	CLIP-seq
MIRT989550	hsa-miR-4322	CLIP-seq
MIRT989551	hsa-miR-4419b	CLIP-seq
MIRT989552	hsa-miR-4436b-3p	CLIP-seq
MIRT989553	hsa-miR-4442	CLIP-seq
MIRT989556	hsa-miR-4467	CLIP-seq
MIRT989557	hsa-miR-4478	CLIP-seq
MIRT989558	hsa-miR-4483	CLIP-seq
MIRT989562	hsa-miR-4520a-3p	CLIP-seq
MIRT989564	hsa-miR-4526	CLIP-seq
MIRT1993301	hsa-miR-4530	CLIP-seq
MIRT989566	hsa-miR-4645-3p	CLIP-seq
MIRT989567	hsa-miR-4648	CLIP-seq
MIRT989568	hsa-miR-4650-5p	CLIP-seq
MIRT1993302	hsa-miR-4651	CLIP-seq
MIRT989569	hsa-miR-4653-3p	CLIP-seq
MIRT989570	hsa-miR-4654	CLIP-seq
MIRT1993303	hsa-miR-4664-5p	CLIP-seq
MIRT989573	hsa-miR-4684-5p	CLIP-seq
MIRT989575	hsa-miR-4689	CLIP-seq
MIRT989576	hsa-miR-4690-3p	CLIP-seq
MIRT1993304	hsa-miR-4690-5p	CLIP-seq
MIRT989578	hsa-miR-4698	CLIP-seq
MIRT1993305	hsa-miR-4701-3p	CLIP-seq
MIRT1993306	hsa-miR-4707-3p	CLIP-seq
MIRT989581	hsa-miR-4728-5p	CLIP-seq
MIRT989582	hsa-miR-4734	CLIP-seq
MIRT989583	hsa-miR-4736	CLIP-seq
MIRT989584	hsa-miR-4743	CLIP-seq
MIRT989586	hsa-miR-4763-3p	CLIP-seq
MIRT989587	hsa-miR-4767	CLIP-seq
MIRT989588	hsa-miR-4769-5p	CLIP-seq
MIRT989589	hsa-miR-4784	CLIP-seq
MIRT989590	hsa-miR-4787-5p	CLIP-seq
MIRT989591	hsa-miR-4802-3p	CLIP-seq
MIRT989592	hsa-miR-485-5p	CLIP-seq
MIRT989594	hsa-miR-497	CLIP-seq
MIRT989597	hsa-miR-513a-3p	CLIP-seq
MIRT1993307	hsa-miR-513a-5p	CLIP-seq
MIRT1993309	hsa-miR-542-5p	CLIP-seq
MIRT989599	hsa-miR-544b	CLIP-seq
MIRT1993310	hsa-miR-548c-3p	CLIP-seq
MIRT1993311	hsa-miR-550a	CLIP-seq
MIRT989601	hsa-miR-564	CLIP-seq
MIRT989602	hsa-miR-571	CLIP-seq
MIRT989604	hsa-miR-582-5p	CLIP-seq
MIRT1993312	hsa-miR-604	CLIP-seq
MIRT989605	hsa-miR-607	CLIP-seq
MIRT1993313	hsa-miR-608	CLIP-seq
MIRT989607	hsa-miR-615-5p	CLIP-seq
MIRT989609	hsa-miR-634	CLIP-seq
MIRT989610	hsa-miR-637	CLIP-seq
MIRT1993315	hsa-miR-647	CLIP-seq
MIRT989612	hsa-miR-661	CLIP-seq
MIRT1993316	hsa-miR-663	CLIP-seq
MIRT1993318	hsa-miR-665	CLIP-seq
MIRT1993319	hsa-miR-761	CLIP-seq
MIRT989616	hsa-miR-924	CLIP-seq
MIRT989617	hsa-miR-935	CLIP-seq
MIRT989504	hsa-miR-1224-3p	CLIP-seq
MIRT989505	hsa-miR-1260	CLIP-seq
MIRT989506	hsa-miR-1260b	CLIP-seq
MIRT989508	hsa-miR-1280	CLIP-seq
MIRT989509	hsa-miR-1286	CLIP-seq
MIRT989515	hsa-miR-15a	CLIP-seq
MIRT989516	hsa-miR-15b	CLIP-seq
MIRT989517	hsa-miR-16	CLIP-seq
MIRT989518	hsa-miR-195	CLIP-seq
MIRT989521	hsa-miR-3065-3p	CLIP-seq
MIRT989528	hsa-miR-3195	CLIP-seq
MIRT989535	hsa-miR-3687	CLIP-seq
MIRT989540	hsa-miR-3945	CLIP-seq
MIRT989542	hsa-miR-424	CLIP-seq
MIRT989552	hsa-miR-4436b-3p	CLIP-seq
MIRT989553	hsa-miR-4442	CLIP-seq
MIRT989584	hsa-miR-4743	CLIP-seq
MIRT989594	hsa-miR-497	CLIP-seq
MIRT989533	hsa-miR-3657	CLIP-seq
MIRT989548	hsa-miR-4299	CLIP-seq
MIRT989555	hsa-miR-4456	CLIP-seq
MIRT989571	hsa-miR-4660	CLIP-seq
MIRT989600	hsa-miR-548q	CLIP-seq
MIRT989533	hsa-miR-3657	CLIP-seq
MIRT989548	hsa-miR-4299	CLIP-seq
MIRT989555	hsa-miR-4456	CLIP-seq
MIRT989571	hsa-miR-4660	CLIP-seq
MIRT989600	hsa-miR-548q	CLIP-seq
MIRT989500	hsa-miR-101	CLIP-seq
MIRT989503	hsa-miR-1207-5p	CLIP-seq
MIRT989512	hsa-miR-144	CLIP-seq
MIRT989515	hsa-miR-15a	CLIP-seq
MIRT989516	hsa-miR-15b	CLIP-seq
MIRT989517	hsa-miR-16	CLIP-seq
MIRT989518	hsa-miR-195	CLIP-seq
MIRT989525	hsa-miR-3150b-3p	CLIP-seq
MIRT989531	hsa-miR-3591-3p	CLIP-seq
MIRT989542	hsa-miR-424	CLIP-seq
MIRT989545	hsa-miR-4294	CLIP-seq
MIRT989565	hsa-miR-4635	CLIP-seq
MIRT989566	hsa-miR-4645-3p	CLIP-seq
MIRT989569	hsa-miR-4653-3p	CLIP-seq
MIRT989575	hsa-miR-4689	CLIP-seq
MIRT989578	hsa-miR-4698	CLIP-seq
MIRT989583	hsa-miR-4736	CLIP-seq
MIRT989586	hsa-miR-4763-3p	CLIP-seq
MIRT989589	hsa-miR-4784	CLIP-seq
MIRT989591	hsa-miR-4802-3p	CLIP-seq
MIRT989593	hsa-miR-495	CLIP-seq
MIRT989594	hsa-miR-497	CLIP-seq
MIRT989597	hsa-miR-513a-3p	CLIP-seq
MIRT989598	hsa-miR-526b	CLIP-seq
MIRT989599	hsa-miR-544b	CLIP-seq
MIRT989602	hsa-miR-571	CLIP-seq
MIRT989603	hsa-miR-578	CLIP-seq
MIRT989604	hsa-miR-582-5p	CLIP-seq
MIRT989605	hsa-miR-607	CLIP-seq
MIRT989612	hsa-miR-661	CLIP-seq
MIRT989616	hsa-miR-924	CLIP-seq
MIRT989617	hsa-miR-935	CLIP-seq

Transcription factors

Show/Hide all(2)

Transcription factor	Regulation	Reference
KLF5	Activation	18774944
SREBF1	Unknown	10520861;11790787;17449569

Show/Hide all(41)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001649	Process	Osteoblast differentiation	HDA	16210410
GO:0002068	Process	Glandular epithelial cell development	IEA
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0004313	Function	[acyl-carrier-protein] S-acetyltransferase activity	IEA
GO:0004314	Function	[acyl-carrier-protein] S-malonyltransferase activity	IEA
GO:0004315	Function	3-oxoacyl-[acyl-carrier-protein] synthase activity	IEA
GO:0004316	Function	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity	IEA
GO:0004317	Function	3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity	IEA
GO:0004320	Function	Oleoyl-[acyl-carrier-protein] hydrolase activity	IEA
GO:0005515	Function	Protein binding	IPI	18022563, 23427160, 25959826, 27478939, 32296183, 32814053
GO:0005794	Component	Golgi apparatus	IDA
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	IDA
GO:0006084	Process	Acetyl-CoA metabolic process	IEA
GO:0006631	Process	Fatty acid metabolic process	TAS	7835891
GO:0006633	Process	Fatty acid biosynthetic process	IEA
GO:0008611	Process	Ether lipid biosynthetic process	IEA
GO:0008659	Function	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity	IEA
GO:0008693	Function	3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity	IEA
GO:0016020	Component	Membrane	HDA	16210410, 19946888
GO:0016295	Function	Myristoyl-[acyl-carrier-protein] hydrolase activity	IEA
GO:0016296	Function	Palmitoyl-[acyl-carrier-protein] hydrolase activity	IEA
GO:0030223	Process	Neutrophil differentiation	IEA
GO:0030224	Process	Monocyte differentiation	IEA
GO:0030879	Process	Mammary gland development	IEA
GO:0031177	Function	Phosphopantetheine binding	IEA
GO:0031325	Process	Positive regulation of cellular metabolic process	TAS
GO:0042470	Component	Melanosome	IEA
GO:0042587	Component	Glycogen granule	IEA
GO:0042802	Function	Identical protein binding	IEA
GO:0045296	Function	Cadherin binding	HDA	25468996
GO:0045540	Process	Regulation of cholesterol biosynthetic process	TAS
GO:0046949	Process	Fatty-acyl-CoA biosynthetic process	TAS
GO:0047117	Function	Enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity	IEA
GO:0047451	Function	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity	IEA
GO:0070062	Component	Extracellular exosome	HDA	19056867, 20458337, 23533145
GO:0071353	Process	Cellular response to interleukin-4	IEA
GO:0090557	Process	Establishment of endothelial intestinal barrier	IEA
GO:0102131	Function	3-oxo-glutaryl-[acp] methyl ester reductase activity	IEA
GO:0102132	Function	3-oxo-pimeloyl-[acp] methyl ester reductase activity	IEA

MIM	HGNC	e!Ensembl
600212	3594	ENSG00000169710

Protein

UniProt ID

P49327

Protein name

Fatty acid synthase (EC 2.3.1.85) (Type I fatty acid synthase) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoac

Protein function

Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH. This multifunctional protein contains 7 catalytic ac

PDB

1XKT , 2CG5 , 2JFD , 2JFK , 2PX6 , 3HHD , 3TJM , 4PIV , 4W82 , 4W9N , 4Z49 , 5C37 , 6NNA , 7MHD , 7MHE , 8EYI , 8EYK , 8G7X , 8GKC , 8VF7 , 8VG4 , 8VLE , 8VLO , 8VLP , 8VM0 , 8VM5 , 8VM6 , 8VM7 , 8VMC , 8VMD , 9B7Z , 9B80 , 9MJ9

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00109	ketoacyl-synt	1 → 239	Beta-ketoacyl synthase, N-terminal domain	Domain
PF02801	Ketoacyl-synt_C	243 → 360	Beta-ketoacyl synthase, C-terminal domain	Domain
PF16197	KAsynt_C_assoc	362 → 472	Ketoacyl-synthetase C-terminal extension	Family
PF00698	Acyl_transf_1	493 → 810	Acyl transferase domain	Domain
PF14765	PS-DH	865 → 1108	Polyketide synthase dehydratase	Domain
PF08242	Methyltransf_12	1243 → 1342	Methyltransferase domain	Domain
PF00107	ADH_zinc_N	1679 → 1816	Zinc-binding dehydrogenase	Family
PF08659	KR	1885 → 2065	KR domain	Family
PF00550	PP-binding	2125 → 2192	Phosphopantetheine attachment site	Domain
PF00975	Thioesterase	2242 → 2501	Thioesterase domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Ubiquitous. Prominent expression in brain, lung, liver and mammary gland. {ECO:0000269|PubMed:7567999, ECO:0000269|PubMed:7595075}.

Sequence

MEEVVIAGMSGKLPESENLQEFWDNLIGGVDMVTDDDRRWKAGLYGLPRRSGKLKDLSRF
DASFFGVHPKQAHTMDPQLRLLLEVTYEAIVDGGINPDSLRGTHTGVWVGVSGSETSEAL
SRDPETLVGYSMVGCQRAMMANRLSFFFDFRGPSIALDTACSSSLMALQNAYQAIHSGQC
PAAIVGGINVLLKPNTSVQFLRLGMLSPEGTCKAFDTAGNGYCRSEGVVAVLLTKKSLAR
RVYATILNAGTNTDGFKEQGVTFPSGDIQEQLIRSLYQSAGVAPESFEYIEAHGTGTKVG
DPQELNGITRALCATRQEPLLIGSTKSNMGHPEPASGLAALAKVLLSLEHGLWAPNLHFH
SPNPEIPALLDGRLQVVDQPLPVRGGNVGINSFGFGGSNVHIILRPNTQPPPAPAPHATL
PRLLRASGRTPEAVQKLLEQGLRHSQDLAFLSMLNDIAAVPATAMPFRGYAVLGGERGGP
EVQQVPAGERPLWFICSGMGTQWRGMGLSLMRLDRFRDSILRSDEAVKPFGLKVSQLLLS
TDESTFDDIVHSFVSLTAIQIGLIDLLSCMGLRPDGIVGHSLGEVACGYADGCLSQEEAV
LAAYWRGQCIKEAHLPPGAMAAVGLSWEECKQRCPPGVVPACHNSKDTVTISGPQAPVFE
FVEQLRKEGVFAKEVRTGGMAFHSYFMEAIAPPLLQELKKVIREPKPRSARWLSTSIPEA
QWHSSLARTSSAEYNVNNLVSPVLFQEALWHVPEHAVVLEIAPHALLQAVLKRGLKPSCT
IIPLMKKDHRDNLEFFLAGIGRLHLSGIDANPNALFPPVEFPAPRGTPLISPLIKWDHSL
AWDVPAAEDFPNGSGSPSAAIYNIDTSSESPDHYLVDHTLDGRVLFPATGYLSIVWKTLA
RALGLGVEQLPVVFEDVVLHQATILPKTGTVSLEVRLLEASRAFEVSENGNLVVSGKVYQ
WDDPDPRLFDHPESPTPNPTEPLFLAQAEVYKELRLRGYDYGPHFQGILEASLEGDSGRL
LWKDNWVSFMDTMLQMSILGSAKHGLYLPTRVTAIHIDPATHRQKLYTLQDKAQVADVVV
SRWLRVTVAGGVHISGLHTESAPRRQQEQQVPILEKFCFTPHTEEGCLSERAALQEELQL
CKGLVQALQTKVTQQGLKMVVPGLDGAQIPRDPSQQELPRLLSAACRLQLNGNLQLELAQ
VLAQERPKLPEDPLLSGLLDSPALKACLDTAVENMPSLKMKVVEVLAGHGHLYSRIPGLL
SPHPLLQLSYTATDRHPQALEAAQAELQQHDVAQGQWDPADPAPSALGSADLLVCNCAVA
ALGDPASALSNMVAALREGGFLLLHTLLRGHPLGDIVAFLTSTEPQYGQGILSQDAWESL
FSRVSLRLVGLKKSFYGSTLFLCRRPTPQDSPIFLPVDDTSFRWVESLKGILADEDSSRP
VWLKAINCATSGVVGLVNCLRREPGGNRLRCVLLSNLSSTSHVPEVDPGSAELQKVLQGD
LVMNVYRDGAWGAFRHFLLEEDKPEEPTAHAFVSTLTRGDLSSIRWVCSSLRHAQPTCPG
AQLCTVYYASLNFRDIMLATGKLSPDAIPGKWTSQDSLLGMEFSGRDASGKRVMGLVPAK
GLATSVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYYALVVRGRVRPGETLLIHSGSGGV
GQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLDSTSFANSRDTSFEQHVLWHTGGKG
VDLVLNSLAEEKLQASVRCLATHGRFLEIGKFDLSQNHPLGMAIFLKNVTFHGVLLDAFF
NESSADWREVWALVQAGIRDGVVRPLKCTVFHGAQVEDAFRYMAQGKHIGKVVVQVLAEE
PEAVLKGAKPKLMSAISKTFCPAHKSYIIAGGLGGFGLELAQWLIQRGVQKLVLTSRSGI
RTGYQAKQVRRWRRQGVQVQVSTSNISSLEGARGLIAEAAQLGPVGGVFNLAVVLRDGLL
ENQTPEFFQDVCKPKYSGTLNLDRVTREACPELDYFVVFSSVSCGRGNAGQSNYGFANSA
MERICEKRRHEGLPGLAVQWGAIGDVGILVETMSTNDTIVSGTLPQRMASCLEVLDLFLN
QPHMVLSSFVLAEKAAAYRDRDSQRDLVEAVAHILGIRDLAAVNLDSSLADLGLDSLMSV
EVRQTLERELNLVLSVREVRQLTLRKLQELSSKADEASELACPTPKEDGLAQQQTQLNLR
SLLVNPEGPTLMRLNSVQSSERPLFLVHPIEGSTTVFHSLASRLSIPTYGLQCTRAAPLD
SIHSLAAYYIDCIRQVQPEGPYRVAGYSYGACVAFEMCSQLQAQQSPAPTHNSLFLFDGS
PTYVLAYTQSYRAKLTPGCEAEAETEAICFFVQQFTDMEHNRVLEALLPLKGLEERVAAA
VDLIIKSHQGLDRQELSFAARSFYYKLRAAEQYTPKAKYHGNVMLLRAKTGGAYGEDLGA
DYNLSQVCDGKVSVHVIEGDHRTLLEGSGLESIISIIHSSLAEPRVSVREG

Sequence length

2511

Interactions

View interactions

Show/Hide Unknown Diseases (3)

Disease term	Disease name	Source
Unknown
Neurodevelopmental Disorders	neurodevelopmental disorder	GenCC
Mental Depression	Mental Depression	GWAS
Metabolic Syndrome	Metabolic Syndrome	GWAS

Show/Hide Text Mining Associations (165)

Disease Name	Relationship Type	References
Associations from Text Mining
Aberrant Crypt Foci	Associate	19358283
Acute Coronary Syndrome	Associate	23305094
Adenocarcinoma	Associate	19471962, 36650542
Adenocarcinoma Follicular	Associate	22135723
Adenocarcinoma of Lung	Associate	28400509, 33465697
Adenoma	Stimulate	9006336
Adenomatous Polyposis Coli	Stimulate	9006336
Adrenocortical Carcinoma	Associate	33626208
Agnosia	Associate	40133809
Allan Herndon Dudley syndrome	Associate	32961983
Antiphospholipid Syndrome	Associate	22949932
Barrett Esophagus	Associate	19471962
Breast Neoplasms	Associate	15870086, 16048908, 17352212, 17565694, 17631500, 18253084, 19116881, 21080941, 21643005, 22886728, 25751270, 26334757, 26349913, 26632252, 27270654 View all (17 more)
Breast Neoplasms	Stimulate	18022396, 24894151
Breast Neoplasms Male	Associate	37696831
Cachexia	Associate	25151963
Carcinogenesis	Associate	19358283, 22485149, 23725225, 27713175, 38003694
Carcinoma Acinar Cell	Associate	33843033
Carcinoma Giant Cell	Associate	24676584
Carcinoma Hepatocellular	Associate	16855382, 20173757, 22949843, 23427160, 25826294, 27357947, 30176945, 32536483, 34311471, 34981667, 37673328
Carcinoma Hepatocellular	Inhibit	27758890
Carcinoma in Situ	Associate	20228782
Carcinoma Non Small Cell Lung	Associate	22886728, 25227797, 35806291, 36411628
Carcinoma Pancreatic Ductal	Associate	19723916, 36650542
Carcinoma Renal Cell	Associate	28984208, 37467634, 37626050
Carcinoma Squamous Cell	Associate	19517019, 34879004
Cardiomyopathy Hypertrophic	Associate	30338905
Cardiovascular Diseases	Associate	32231389
Central Nervous System Diseases	Associate	35633176
Cholangiocarcinoma	Associate	36635270, 37821935
Choriocarcinoma	Associate	19893031
Colonic Neoplasms	Associate	28260110
Colorectal Neoplasms	Associate	18253084, 18516290, 19358283, 19790197, 22312135, 23725225, 25970773, 27139420, 28260110, 28268248, 34879004, 36430738, 37202390, 37416772, 9006336
Colorectal Neoplasms	Stimulate	18955444, 32155177
COVID 19	Associate	36293257, 37291167
Cushing Syndrome	Associate	18782871
Developmental Disabilities	Associate	40185395
Diabetes Gestational	Inhibit	24262292
Diabetes Mellitus Type 2	Inhibit	19543203
Diabetes Mellitus Type 2	Associate	29620215, 33788629
Drug Related Side Effects and Adverse Reactions	Associate	15235125, 15533929, 22380770
Drug Related Side Effects and Adverse Reactions	Inhibit	25738895
Dysplastic Nevus Syndrome	Associate	29966661, 34402100
Endocrine System Diseases	Associate	40055794
Endometrial Neoplasms	Associate	15144342, 24105476, 33577023, 35008502, 37305395, 40244177
Endotoxemia	Inhibit	30422702
Esophageal Squamous Cell Carcinoma	Associate	19471962, 36965032
Fatty Liver	Associate	18830996, 24478438, 29786745, 36251517
Fibrosis	Associate	36251517
Gerstmann Syndrome	Associate	17618104, 25227797, 25735330, 25826294, 37774841
Gestational Trophoblastic Disease	Associate	19893031
Glioblastoma	Associate	26808816, 40133683
Glioma	Associate	26808816, 34573317
Glucose Intolerance	Associate	19300427
Granuloma Giant Cell	Associate	24676584
Hearing Loss Bilateral	Associate	31006709
Heart Failure	Associate	30272299
Hepatitis C	Associate	18830996, 23427160
Hepatitis C	Stimulate	24478438, 28883690
Hereditary Breast and Ovarian Cancer Syndrome	Associate	10716717, 15235125
Hereditary Breast and Ovarian Cancer Syndrome	Stimulate	18796435
Hereditary leiomyomatosis and renal cell cancer	Associate	27375065
Histiocytosis Langerhans Cell	Associate	22949932
Hypertension	Associate	27090298
Hypoparathyroidism	Associate	40185395
Hypopituitarism	Associate	40185395
Hypothyroidism	Associate	30272292
Hypoxia	Associate	18355682
Idiopathic Pulmonary Fibrosis	Inhibit	38117249
Infections	Stimulate	24478438
Inflammation	Associate	26718495, 27270654, 36293257
Insulin Resistance	Stimulate	20299470
Insulin Resistance	Associate	37111057
Iron Overload	Associate	21114893
Leiomyosarcoma	Associate	28654693
Leukemia Myeloid Acute	Associate	33742137
Leukemia Promyelocytic Acute	Associate	33742137
Leukoplakia Hairy	Associate	15047835
Lipoma	Associate	8022791
Liposarcoma	Associate	18259941, 20372807
Lung Neoplasms	Associate	15736468, 21768098, 25227797, 28400509, 38069382
Lymphatic Diseases	Associate	19362044
Lymphatic Metastasis	Associate	26936091
Lymphatic Metastasis	Stimulate	27139420, 35597782
Lymphoma Extranodal NK T Cell	Associate	23969921
Lymphoma Mantle Cell	Associate	22485149, 24457957
Lymphoma Non Hodgkin	Associate	20228782
Lymphoma T Cell Peripheral	Associate	25674239
Malformations of Cortical Development Group I	Associate	34620841
Melanoma	Associate	15467715, 37072838, 37801083, 37857525
Melanoma	Stimulate	15920554
Melanoma	Inhibit	37481560
Metabolic Diseases	Associate	27090298, 33978191, 34526523, 35843982
Mitochondrial Diseases	Associate	34620841
Multiple Myeloma	Associate	18543396
Muscle Neoplasms	Associate	29687616
Myotonic Dystrophy	Inhibit	34462518
Nasopharyngeal Carcinoma	Associate	23208675, 29228426, 34546840, 35628510
Neoplasm Invasiveness	Associate	15144342
Neoplasm Metastasis	Associate	15144342, 18519708, 23208675, 25970773, 26334757, 26425687, 26632252, 26936091, 27139420, 27714708, 35468964, 35566090, 37696831
Neoplasms	Associate	10716717, 11082286, 15138278, 15144342, 15235125, 15507492, 15533929, 15920554, 16215233, 17352212, 17565694, 18253084, 18723500, 18796435, 18955444 View all (73 more)
Neoplasms	Stimulate	15736468, 23319743, 23725225, 25177021, 31894270, 32319557, 34402100, 37919060
Neoplasms	Inhibit	27713175, 32685475
Nerve Degeneration	Associate	35872948
Neurodegenerative Diseases	Associate	35633176
Nevus Epithelioid and Spindle Cell	Associate	15467715
Nevus Pigmented	Associate	15920554
Non alcoholic Fatty Liver Disease	Associate	21656912, 29786745, 37729806
Obesity	Associate	15113941, 15138278, 15235125, 18955444, 19300427, 19876008, 19913854, 21840420, 22278432, 24285872, 27758890, 27768648, 28387458, 29620215, 30422702
Obesity	Inhibit	17618104, 19543203
Obesity	Stimulate	20299470, 34526523
Obesity Maternal	Inhibit	24262292
Opitz GBBB Syndrome X Linked	Associate	33405298
Osteoarthritis	Associate	37291167
Osteosarcoma	Associate	25034529, 25674245, 27813492, 33289496, 33405298, 35566090, 38217543
Ovarian Neoplasms	Stimulate	15920554
Ovarian Neoplasms	Associate	21970855, 22653145, 25151963, 25302649, 25433947, 25947066, 28086243, 32913236, 38003694
Overnutrition	Associate	20299470
Overweight	Associate	18955444, 20679621
Overweight	Inhibit	19543203
Pancreatic Intraductal Neoplasms	Stimulate	19723916
Pancreatic Neoplasms	Associate	17695548, 19723916, 28639885, 37302809
Pancreatitis Chronic	Stimulate	19723916
Peripheral Nervous System Diseases	Associate	36741233
Peritonitis	Stimulate	26514456
Personality Disorders	Associate	25868764
Personality Disorders	Stimulate	33843033
Phyllodes Tumor of the Prostate	Associate	33807257
Polyposis Syndrome Hereditary Mixed 1	Associate	19358283
Precancerous Conditions	Associate	36635270
Precursor Cell Lymphoblastic Leukemia Lymphoma	Associate	32826925
Prostatic malacoplakia associated with prostatic abscess	Associate	32655718
Prostatic Neoplasms	Associate	11384102, 15533929, 15556626, 17146477, 18355682, 18774944, 19362044, 20679621, 22127986, 22343504, 24391718, 24907642, 25177021, 25767870, 25868764 View all (13 more)
Prostatic Neoplasms	Inhibit	15870086
Prostatic Neoplasms	Stimulate	32319557, 36650542
Prostatic Neoplasms Castration Resistant	Stimulate	18519708
Prostatic Neoplasms Castration Resistant	Associate	38593154
Prostatitis	Associate	17146477, 22127986, 32319557, 38112617
Radiation Injuries	Associate	25738895
Renal Insufficiency Chronic	Stimulate	31109090
Reperfusion Injury	Stimulate	20440768
Retinal Dystrophies	Associate	40185395
Salivary Duct Calculi	Associate	33843033
Salivary Gland Neoplasms	Associate	33843033
Secretory breast carcinoma	Associate	33843033
Sezary Syndrome	Associate	27039262
Small Cell Lung Carcinoma	Associate	34564955
Squamous Cell Carcinoma of Head and Neck	Associate	19362044, 29966661, 32961983
Squamous Cell Carcinoma of Head and Neck	Stimulate	34402100
Stomach Neoplasms	Associate	26514456, 26811494, 26936091, 31646566
Systemic Inflammatory Response Syndrome	Associate	35872948
Tertiary Lymphoid Structures	Associate	19362044
Thyroid cancer Hurthle cell	Associate	22135723
Thyroid Cancer Papillary	Stimulate	22135723
Thyroid Carcinoma Anaplastic	Stimulate	22135723
Thyroid Neoplasms	Associate	22135723
Triple Negative Breast Neoplasms	Associate	25213330, 25751270, 29751678, 30875891
Trophoblastic Neoplasms	Associate	19893031
Urinary Bladder Neoplasms	Associate	32792852, 34819038, 35127296, 35392075, 35480865, 37919060, 38186002, 38218866, 39867879
Uterine Cervical Neoplasms	Associate	35507982, 40764609
Uterine Cervical Neoplasms	Stimulate	35597782
Varicocele	Associate	31006709, 34975746
Weight Loss	Associate	19913854
Weight Loss	Inhibit	34526523
Wilms Tumor	Associate	31894270

FASN (fatty acid synthase)