Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs Other IDs Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	11160
Gene name Gene Name - the full gene name approved by the HGNC.	ER lipid raft associated 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	ERLIN2
Synonyms (NCBI Gene) Gene synonyms aliases	C8orf2, Erlin-2, NET32, SPFH2, SPG18, SPG18A, SPG18B
Chromosome Chromosome number	8
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	8p11.23
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a member of the SPFH domain-containing family of lipid raft-associated proteins. The encoded protein is localized to lipid rafts of the endoplasmic reticulum and plays a critical role in inositol 1,4,5-trisphosphate (IP3) signaling by me

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SNP ID	Visualize variation	Clinical significance	Consequence
rs587776893	->AC	Pathogenic	Genic downstream transcript variant, frameshift variant, coding sequence variant
rs763958615	A>G,T	Likely-pathogenic	Coding sequence variant, missense variant, genic downstream transcript variant
rs1057519172	G>A	Likely-pathogenic	Splice acceptor variant
rs1585907153	A>-	Pathogenic	Coding sequence variant, frameshift variant
rs1585919102	->GGCCATTGCTTCCA	Likely-pathogenic	Coding sequence variant, frameshift variant, genic downstream transcript variant

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miRTarBase ID	miRNA	Experiments	Reference
MIRT004154	hsa-miR-192-5p	Microarray	16822819
MIRT025281	hsa-miR-34a-5p	Proteomics	21566225
MIRT025281	hsa-miR-34a-5p	Proteomics	21566225
MIRT025281	hsa-miR-34a-5p	Proteomics	21566225
MIRT031903	hsa-miR-16-5p	Proteomics	18668040
MIRT048896	hsa-miR-93-5p	CLASH	23622248
MIRT047981	hsa-miR-30c-5p	CLASH	23622248
MIRT043639	hsa-miR-326	CLASH	23622248
MIRT739790	hsa-miR-2355-5p	CLIP-seq
MIRT739791	hsa-miR-3679-3p	CLIP-seq
MIRT739789	hsa-miR-4267	CLIP-seq
MIRT739788	hsa-miR-4268	CLIP-seq
MIRT739787	hsa-miR-4691-5p	CLIP-seq
MIRT969352	hsa-miR-105	CLIP-seq
MIRT969353	hsa-miR-1184	CLIP-seq
MIRT969354	hsa-miR-1205	CLIP-seq
MIRT969355	hsa-miR-1208	CLIP-seq
MIRT969356	hsa-miR-1246	CLIP-seq
MIRT969357	hsa-miR-1253	CLIP-seq
MIRT969358	hsa-miR-125a-3p	CLIP-seq
MIRT969359	hsa-miR-1271	CLIP-seq
MIRT969360	hsa-miR-1278	CLIP-seq
MIRT969361	hsa-miR-1283	CLIP-seq
MIRT969362	hsa-miR-1290	CLIP-seq
MIRT969363	hsa-miR-15a	CLIP-seq
MIRT969364	hsa-miR-15b	CLIP-seq
MIRT969365	hsa-miR-16	CLIP-seq
MIRT969366	hsa-miR-181a	CLIP-seq
MIRT969367	hsa-miR-181b	CLIP-seq
MIRT969368	hsa-miR-181c	CLIP-seq
MIRT969369	hsa-miR-181d	CLIP-seq
MIRT969370	hsa-miR-182	CLIP-seq
MIRT969371	hsa-miR-186	CLIP-seq
MIRT969372	hsa-miR-1908	CLIP-seq
MIRT969373	hsa-miR-195	CLIP-seq
MIRT969374	hsa-miR-196a	CLIP-seq
MIRT969375	hsa-miR-196b	CLIP-seq
MIRT969376	hsa-miR-2117	CLIP-seq
MIRT969377	hsa-miR-216b	CLIP-seq
MIRT969378	hsa-miR-2276	CLIP-seq
MIRT969379	hsa-miR-3121-3p	CLIP-seq
MIRT969380	hsa-miR-3133	CLIP-seq
MIRT969381	hsa-miR-3150a-5p	CLIP-seq
MIRT969382	hsa-miR-3150b-5p	CLIP-seq
MIRT969383	hsa-miR-3158-5p	CLIP-seq
MIRT969384	hsa-miR-3163	CLIP-seq
MIRT969385	hsa-miR-3167	CLIP-seq
MIRT969386	hsa-miR-3194-5p	CLIP-seq
MIRT969387	hsa-miR-340	CLIP-seq
MIRT969388	hsa-miR-34b	CLIP-seq
MIRT969389	hsa-miR-3591-5p	CLIP-seq
MIRT969390	hsa-miR-3662	CLIP-seq
MIRT969391	hsa-miR-3675-3p	CLIP-seq
MIRT969392	hsa-miR-3682-5p	CLIP-seq
MIRT969393	hsa-miR-3688-3p	CLIP-seq
MIRT969394	hsa-miR-3919	CLIP-seq
MIRT969395	hsa-miR-3934	CLIP-seq
MIRT969396	hsa-miR-3974	CLIP-seq
MIRT969397	hsa-miR-412	CLIP-seq
MIRT969398	hsa-miR-424	CLIP-seq
MIRT969399	hsa-miR-4262	CLIP-seq
MIRT969400	hsa-miR-4264	CLIP-seq
MIRT969401	hsa-miR-4272	CLIP-seq
MIRT969402	hsa-miR-4273	CLIP-seq
MIRT969403	hsa-miR-4282	CLIP-seq
MIRT969404	hsa-miR-4326	CLIP-seq
MIRT969405	hsa-miR-4420	CLIP-seq
MIRT969406	hsa-miR-4447	CLIP-seq
MIRT969407	hsa-miR-4454	CLIP-seq
MIRT969408	hsa-miR-4472	CLIP-seq
MIRT969409	hsa-miR-4476	CLIP-seq
MIRT969410	hsa-miR-4481	CLIP-seq
MIRT969411	hsa-miR-4517	CLIP-seq
MIRT969412	hsa-miR-4524	CLIP-seq
MIRT969413	hsa-miR-4641	CLIP-seq
MIRT969414	hsa-miR-4643	CLIP-seq
MIRT969415	hsa-miR-4651	CLIP-seq
MIRT969416	hsa-miR-4684-5p	CLIP-seq
MIRT739787	hsa-miR-4691-5p	CLIP-seq
MIRT969417	hsa-miR-4698	CLIP-seq
MIRT969418	hsa-miR-4717-3p	CLIP-seq
MIRT969419	hsa-miR-4729	CLIP-seq
MIRT969420	hsa-miR-4730	CLIP-seq
MIRT969421	hsa-miR-4745-5p	CLIP-seq
MIRT969422	hsa-miR-4756-3p	CLIP-seq
MIRT969423	hsa-miR-4758-5p	CLIP-seq
MIRT969424	hsa-miR-4762-5p	CLIP-seq
MIRT969425	hsa-miR-4763-5p	CLIP-seq
MIRT969426	hsa-miR-4765	CLIP-seq
MIRT969427	hsa-miR-4772-3p	CLIP-seq
MIRT969428	hsa-miR-4790-3p	CLIP-seq
MIRT969429	hsa-miR-4797-3p	CLIP-seq
MIRT969430	hsa-miR-493	CLIP-seq
MIRT969431	hsa-miR-494	CLIP-seq
MIRT969432	hsa-miR-497	CLIP-seq
MIRT969433	hsa-miR-503	CLIP-seq
MIRT969434	hsa-miR-518a-5p	CLIP-seq
MIRT969435	hsa-miR-518d-5p	CLIP-seq
MIRT969436	hsa-miR-519b-5p	CLIP-seq
MIRT969437	hsa-miR-519c-5p	CLIP-seq
MIRT969438	hsa-miR-520c-5p	CLIP-seq
MIRT969439	hsa-miR-520d-5p	CLIP-seq
MIRT969440	hsa-miR-524-5p	CLIP-seq
MIRT969441	hsa-miR-526a	CLIP-seq
MIRT969442	hsa-miR-527	CLIP-seq
MIRT969443	hsa-miR-539	CLIP-seq
MIRT969444	hsa-miR-543	CLIP-seq
MIRT969445	hsa-miR-544	CLIP-seq
MIRT969446	hsa-miR-561	CLIP-seq
MIRT969447	hsa-miR-576-3p	CLIP-seq
MIRT969448	hsa-miR-580	CLIP-seq
MIRT969449	hsa-miR-582-3p	CLIP-seq
MIRT969450	hsa-miR-595	CLIP-seq
MIRT969451	hsa-miR-608	CLIP-seq
MIRT969452	hsa-miR-646	CLIP-seq
MIRT969453	hsa-miR-648	CLIP-seq
MIRT969454	hsa-miR-663	CLIP-seq
MIRT969455	hsa-miR-7	CLIP-seq
MIRT969456	hsa-miR-764	CLIP-seq
MIRT969457	hsa-miR-876-5p	CLIP-seq
MIRT969458	hsa-miR-885-5p	CLIP-seq
MIRT969459	hsa-miR-935	CLIP-seq
MIRT969460	hsa-miR-96	CLIP-seq
MIRT969355	hsa-miR-1208	CLIP-seq
MIRT969363	hsa-miR-15a	CLIP-seq
MIRT969364	hsa-miR-15b	CLIP-seq
MIRT969365	hsa-miR-16	CLIP-seq
MIRT969373	hsa-miR-195	CLIP-seq
MIRT969379	hsa-miR-3121-3p	CLIP-seq
MIRT969392	hsa-miR-3682-5p	CLIP-seq
MIRT969398	hsa-miR-424	CLIP-seq
MIRT969405	hsa-miR-4420	CLIP-seq
MIRT969412	hsa-miR-4524	CLIP-seq
MIRT969432	hsa-miR-497	CLIP-seq
MIRT969433	hsa-miR-503	CLIP-seq
MIRT969452	hsa-miR-646	CLIP-seq
MIRT969458	hsa-miR-885-5p	CLIP-seq
MIRT1987254	hsa-miR-106a	CLIP-seq
MIRT1987255	hsa-miR-106b	CLIP-seq
MIRT969358	hsa-miR-125a-3p	CLIP-seq
MIRT1987256	hsa-miR-1273d	CLIP-seq
MIRT1987257	hsa-miR-1284	CLIP-seq
MIRT1987258	hsa-miR-1293	CLIP-seq
MIRT1987259	hsa-miR-129-3p	CLIP-seq
MIRT1987260	hsa-miR-137	CLIP-seq
MIRT1987261	hsa-miR-142-5p	CLIP-seq
MIRT1987262	hsa-miR-150	CLIP-seq
MIRT969363	hsa-miR-15a	CLIP-seq
MIRT969364	hsa-miR-15b	CLIP-seq
MIRT969365	hsa-miR-16	CLIP-seq
MIRT1987263	hsa-miR-17	CLIP-seq
MIRT969373	hsa-miR-195	CLIP-seq
MIRT1987264	hsa-miR-208a	CLIP-seq
MIRT1987265	hsa-miR-208b	CLIP-seq
MIRT1987266	hsa-miR-20a	CLIP-seq
MIRT1987267	hsa-miR-20b	CLIP-seq
MIRT1987268	hsa-miR-22	CLIP-seq
MIRT1987269	hsa-miR-2277-3p	CLIP-seq
MIRT1987270	hsa-miR-27a	CLIP-seq
MIRT1987271	hsa-miR-27b	CLIP-seq
MIRT1987272	hsa-miR-302a	CLIP-seq
MIRT1987273	hsa-miR-302b	CLIP-seq
MIRT1987274	hsa-miR-302c	CLIP-seq
MIRT1987275	hsa-miR-302d	CLIP-seq
MIRT1987276	hsa-miR-302e	CLIP-seq
MIRT1987277	hsa-miR-3117-5p	CLIP-seq
MIRT969379	hsa-miR-3121-3p	CLIP-seq
MIRT969381	hsa-miR-3150a-5p	CLIP-seq
MIRT969382	hsa-miR-3150b-5p	CLIP-seq
MIRT1987278	hsa-miR-3189-3p	CLIP-seq
MIRT1987279	hsa-miR-323-5p	CLIP-seq
MIRT1987280	hsa-miR-324-5p	CLIP-seq
MIRT969387	hsa-miR-340	CLIP-seq
MIRT1987281	hsa-miR-3619-3p	CLIP-seq
MIRT969392	hsa-miR-3682-5p	CLIP-seq
MIRT1987282	hsa-miR-3691-3p	CLIP-seq
MIRT1987283	hsa-miR-372	CLIP-seq
MIRT1987284	hsa-miR-373	CLIP-seq
MIRT1987285	hsa-miR-3918	CLIP-seq
MIRT969394	hsa-miR-3919	CLIP-seq
MIRT1987286	hsa-miR-3920	CLIP-seq
MIRT969395	hsa-miR-3934	CLIP-seq
MIRT1987287	hsa-miR-3945	CLIP-seq
MIRT969398	hsa-miR-424	CLIP-seq
MIRT1987288	hsa-miR-4253	CLIP-seq
MIRT1987289	hsa-miR-4257	CLIP-seq
MIRT1987290	hsa-miR-4260	CLIP-seq
MIRT1987291	hsa-miR-4283	CLIP-seq
MIRT1987292	hsa-miR-4290	CLIP-seq
MIRT1987293	hsa-miR-4305	CLIP-seq
MIRT1987294	hsa-miR-4312	CLIP-seq
MIRT969405	hsa-miR-4420	CLIP-seq
MIRT1987295	hsa-miR-4436b-3p	CLIP-seq
MIRT1987296	hsa-miR-4436b-5p	CLIP-seq
MIRT969407	hsa-miR-4454	CLIP-seq
MIRT1987297	hsa-miR-4480	CLIP-seq
MIRT1987298	hsa-miR-4483	CLIP-seq
MIRT1987299	hsa-miR-4489	CLIP-seq
MIRT1987300	hsa-miR-4522	CLIP-seq
MIRT969412	hsa-miR-4524	CLIP-seq
MIRT1987301	hsa-miR-4639-5p	CLIP-seq
MIRT969415	hsa-miR-4651	CLIP-seq
MIRT1987302	hsa-miR-4659a-3p	CLIP-seq
MIRT1987303	hsa-miR-4659b-3p	CLIP-seq
MIRT1987304	hsa-miR-4680-5p	CLIP-seq
MIRT1987305	hsa-miR-4714-5p	CLIP-seq
MIRT969419	hsa-miR-4729	CLIP-seq
MIRT1987306	hsa-miR-4731-5p	CLIP-seq
MIRT1987307	hsa-miR-4740-3p	CLIP-seq
MIRT1987308	hsa-miR-4757-5p	CLIP-seq
MIRT1987309	hsa-miR-4761-3p	CLIP-seq
MIRT969425	hsa-miR-4763-5p	CLIP-seq
MIRT1987310	hsa-miR-4764-3p	CLIP-seq
MIRT969427	hsa-miR-4772-3p	CLIP-seq
MIRT1987311	hsa-miR-4777-5p	CLIP-seq
MIRT1987312	hsa-miR-4789-3p	CLIP-seq
MIRT1987313	hsa-miR-4795-5p	CLIP-seq
MIRT1987314	hsa-miR-488	CLIP-seq
MIRT969432	hsa-miR-497	CLIP-seq
MIRT1987315	hsa-miR-498	CLIP-seq
MIRT1987316	hsa-miR-499-5p	CLIP-seq
MIRT969433	hsa-miR-503	CLIP-seq
MIRT1987317	hsa-miR-508-5p	CLIP-seq
MIRT1987318	hsa-miR-5095	CLIP-seq
MIRT1987319	hsa-miR-512-3p	CLIP-seq
MIRT1987320	hsa-miR-513a-3p	CLIP-seq
MIRT1987321	hsa-miR-513a-5p	CLIP-seq
MIRT1987322	hsa-miR-516a-5p	CLIP-seq
MIRT969435	hsa-miR-518d-5p	CLIP-seq
MIRT969436	hsa-miR-519b-5p	CLIP-seq
MIRT969437	hsa-miR-519c-5p	CLIP-seq
MIRT1987323	hsa-miR-519d	CLIP-seq
MIRT1987324	hsa-miR-520a-3p	CLIP-seq
MIRT1987325	hsa-miR-520b	CLIP-seq
MIRT1987326	hsa-miR-520c-3p	CLIP-seq
MIRT969438	hsa-miR-520c-5p	CLIP-seq
MIRT1987327	hsa-miR-520d-3p	CLIP-seq
MIRT1987328	hsa-miR-520e	CLIP-seq
MIRT1987329	hsa-miR-520g	CLIP-seq
MIRT1987330	hsa-miR-520h	CLIP-seq
MIRT969441	hsa-miR-526a	CLIP-seq
MIRT1987331	hsa-miR-552	CLIP-seq
MIRT969447	hsa-miR-576-3p	CLIP-seq
MIRT1987332	hsa-miR-577	CLIP-seq
MIRT969449	hsa-miR-582-3p	CLIP-seq
MIRT969451	hsa-miR-608	CLIP-seq
MIRT1987333	hsa-miR-635	CLIP-seq
MIRT969452	hsa-miR-646	CLIP-seq
MIRT969456	hsa-miR-764	CLIP-seq
MIRT969458	hsa-miR-885-5p	CLIP-seq
MIRT1987334	hsa-miR-93	CLIP-seq
MIRT969352	hsa-miR-105	CLIP-seq
MIRT1987254	hsa-miR-106a	CLIP-seq
MIRT1987255	hsa-miR-106b	CLIP-seq
MIRT969358	hsa-miR-125a-3p	CLIP-seq
MIRT969359	hsa-miR-1271	CLIP-seq
MIRT1987256	hsa-miR-1273d	CLIP-seq
MIRT2221735	hsa-miR-1273f	CLIP-seq
MIRT1987258	hsa-miR-1293	CLIP-seq
MIRT1987259	hsa-miR-129-3p	CLIP-seq
MIRT2221736	hsa-miR-129-5p	CLIP-seq
MIRT2221737	hsa-miR-1302	CLIP-seq
MIRT1987262	hsa-miR-150	CLIP-seq
MIRT969363	hsa-miR-15a	CLIP-seq
MIRT969364	hsa-miR-15b	CLIP-seq
MIRT969365	hsa-miR-16	CLIP-seq
MIRT1987263	hsa-miR-17	CLIP-seq
MIRT2221738	hsa-miR-193a-3p	CLIP-seq
MIRT2221739	hsa-miR-193b	CLIP-seq
MIRT969373	hsa-miR-195	CLIP-seq
MIRT2221740	hsa-miR-1976	CLIP-seq
MIRT1987264	hsa-miR-208a	CLIP-seq
MIRT1987265	hsa-miR-208b	CLIP-seq
MIRT1987266	hsa-miR-20a	CLIP-seq
MIRT1987267	hsa-miR-20b	CLIP-seq
MIRT2221741	hsa-miR-219-1-3p	CLIP-seq
MIRT1987268	hsa-miR-22	CLIP-seq
MIRT2221742	hsa-miR-24	CLIP-seq
MIRT2221743	hsa-miR-2467-5p	CLIP-seq
MIRT1987270	hsa-miR-27a	CLIP-seq
MIRT1987271	hsa-miR-27b	CLIP-seq
MIRT1987272	hsa-miR-302a	CLIP-seq
MIRT1987273	hsa-miR-302b	CLIP-seq
MIRT1987274	hsa-miR-302c	CLIP-seq
MIRT1987275	hsa-miR-302d	CLIP-seq
MIRT1987276	hsa-miR-302e	CLIP-seq
MIRT1987277	hsa-miR-3117-5p	CLIP-seq
MIRT969379	hsa-miR-3121-3p	CLIP-seq
MIRT2221744	hsa-miR-3128	CLIP-seq
MIRT969381	hsa-miR-3150a-5p	CLIP-seq
MIRT969382	hsa-miR-3150b-5p	CLIP-seq
MIRT2221745	hsa-miR-3166	CLIP-seq
MIRT2221746	hsa-miR-3170	CLIP-seq
MIRT2221747	hsa-miR-3182	CLIP-seq
MIRT2221748	hsa-miR-3188	CLIP-seq
MIRT1987278	hsa-miR-3189-3p	CLIP-seq
MIRT1987279	hsa-miR-323-5p	CLIP-seq
MIRT2221749	hsa-miR-330-5p	CLIP-seq
MIRT969387	hsa-miR-340	CLIP-seq
MIRT2221750	hsa-miR-3617	CLIP-seq
MIRT2221751	hsa-miR-3618	CLIP-seq
MIRT1987281	hsa-miR-3619-3p	CLIP-seq
MIRT969392	hsa-miR-3682-5p	CLIP-seq
MIRT1987283	hsa-miR-372	CLIP-seq
MIRT1987284	hsa-miR-373	CLIP-seq
MIRT2221752	hsa-miR-377	CLIP-seq
MIRT1987286	hsa-miR-3920	CLIP-seq
MIRT969395	hsa-miR-3934	CLIP-seq
MIRT969396	hsa-miR-3974	CLIP-seq
MIRT2221753	hsa-miR-3975	CLIP-seq
MIRT969397	hsa-miR-412	CLIP-seq
MIRT969398	hsa-miR-424	CLIP-seq
MIRT1987290	hsa-miR-4260	CLIP-seq
MIRT2221754	hsa-miR-4269	CLIP-seq
MIRT2221755	hsa-miR-4279	CLIP-seq
MIRT1987291	hsa-miR-4283	CLIP-seq
MIRT2221756	hsa-miR-4284	CLIP-seq
MIRT1987292	hsa-miR-4290	CLIP-seq
MIRT2221757	hsa-miR-4298	CLIP-seq
MIRT1987293	hsa-miR-4305	CLIP-seq
MIRT1987294	hsa-miR-4312	CLIP-seq
MIRT2221758	hsa-miR-4327	CLIP-seq
MIRT969405	hsa-miR-4420	CLIP-seq
MIRT1987296	hsa-miR-4436b-5p	CLIP-seq
MIRT969406	hsa-miR-4447	CLIP-seq
MIRT969407	hsa-miR-4454	CLIP-seq
MIRT2221759	hsa-miR-4470	CLIP-seq
MIRT969408	hsa-miR-4472	CLIP-seq
MIRT969409	hsa-miR-4476	CLIP-seq
MIRT1987298	hsa-miR-4483	CLIP-seq
MIRT1987299	hsa-miR-4489	CLIP-seq
MIRT1987300	hsa-miR-4522	CLIP-seq
MIRT969412	hsa-miR-4524	CLIP-seq
MIRT969414	hsa-miR-4643	CLIP-seq
MIRT2221760	hsa-miR-4649-3p	CLIP-seq
MIRT969415	hsa-miR-4651	CLIP-seq
MIRT1987302	hsa-miR-4659a-3p	CLIP-seq
MIRT1987303	hsa-miR-4659b-3p	CLIP-seq
MIRT2221761	hsa-miR-4662a-5p	CLIP-seq
MIRT2221762	hsa-miR-4663	CLIP-seq
MIRT2221763	hsa-miR-4722-3p	CLIP-seq
MIRT969419	hsa-miR-4729	CLIP-seq
MIRT1987306	hsa-miR-4731-5p	CLIP-seq
MIRT1987307	hsa-miR-4740-3p	CLIP-seq
MIRT2221764	hsa-miR-4755-3p	CLIP-seq
MIRT1987308	hsa-miR-4757-5p	CLIP-seq
MIRT969425	hsa-miR-4763-5p	CLIP-seq
MIRT1987310	hsa-miR-4764-3p	CLIP-seq
MIRT969426	hsa-miR-4765	CLIP-seq
MIRT2221765	hsa-miR-4771	CLIP-seq
MIRT969427	hsa-miR-4772-3p	CLIP-seq
MIRT1987311	hsa-miR-4777-5p	CLIP-seq
MIRT2221766	hsa-miR-4778-3p	CLIP-seq
MIRT2221767	hsa-miR-4781-3p	CLIP-seq
MIRT1987312	hsa-miR-4789-3p	CLIP-seq
MIRT2221768	hsa-miR-4803	CLIP-seq
MIRT2221769	hsa-miR-485-5p	CLIP-seq
MIRT1987314	hsa-miR-488	CLIP-seq
MIRT969430	hsa-miR-493	CLIP-seq
MIRT969432	hsa-miR-497	CLIP-seq
MIRT1987315	hsa-miR-498	CLIP-seq
MIRT1987316	hsa-miR-499-5p	CLIP-seq
MIRT969433	hsa-miR-503	CLIP-seq
MIRT1987317	hsa-miR-508-5p	CLIP-seq
MIRT1987318	hsa-miR-5095	CLIP-seq
MIRT1987319	hsa-miR-512-3p	CLIP-seq
MIRT1987321	hsa-miR-513a-5p	CLIP-seq
MIRT1987322	hsa-miR-516a-5p	CLIP-seq
MIRT969435	hsa-miR-518d-5p	CLIP-seq
MIRT969436	hsa-miR-519b-5p	CLIP-seq
MIRT969437	hsa-miR-519c-5p	CLIP-seq
MIRT1987323	hsa-miR-519d	CLIP-seq
MIRT1987324	hsa-miR-520a-3p	CLIP-seq
MIRT1987325	hsa-miR-520b	CLIP-seq
MIRT1987326	hsa-miR-520c-3p	CLIP-seq
MIRT969438	hsa-miR-520c-5p	CLIP-seq
MIRT1987327	hsa-miR-520d-3p	CLIP-seq
MIRT1987328	hsa-miR-520e	CLIP-seq
MIRT1987329	hsa-miR-520g	CLIP-seq
MIRT1987330	hsa-miR-520h	CLIP-seq
MIRT969441	hsa-miR-526a	CLIP-seq
MIRT969443	hsa-miR-539	CLIP-seq
MIRT969444	hsa-miR-543	CLIP-seq
MIRT2221770	hsa-miR-550a	CLIP-seq
MIRT1987331	hsa-miR-552	CLIP-seq
MIRT2221771	hsa-miR-562	CLIP-seq
MIRT2221772	hsa-miR-571	CLIP-seq
MIRT2221773	hsa-miR-579	CLIP-seq
MIRT969451	hsa-miR-608	CLIP-seq
MIRT2221774	hsa-miR-641	CLIP-seq
MIRT969452	hsa-miR-646	CLIP-seq
MIRT969456	hsa-miR-764	CLIP-seq
MIRT969458	hsa-miR-885-5p	CLIP-seq
MIRT2221775	hsa-miR-892b	CLIP-seq
MIRT1987334	hsa-miR-93	CLIP-seq
MIRT969460	hsa-miR-96	CLIP-seq
MIRT969372	hsa-miR-1908	CLIP-seq
MIRT969406	hsa-miR-4447	CLIP-seq
MIRT969408	hsa-miR-4472	CLIP-seq
MIRT969415	hsa-miR-4651	CLIP-seq
MIRT969420	hsa-miR-4730	CLIP-seq
MIRT2221772	hsa-miR-571	CLIP-seq
MIRT969451	hsa-miR-608	CLIP-seq
MIRT969454	hsa-miR-663	CLIP-seq
MIRT969352	hsa-miR-105	CLIP-seq
MIRT2437084	hsa-miR-23a	CLIP-seq
MIRT2437085	hsa-miR-23b	CLIP-seq
MIRT2437086	hsa-miR-23c	CLIP-seq
MIRT2437087	hsa-miR-3671	CLIP-seq
MIRT2437088	hsa-miR-4307	CLIP-seq
MIRT2221761	hsa-miR-4662a-5p	CLIP-seq
MIRT2437089	hsa-miR-4666-5p	CLIP-seq
MIRT2437090	hsa-miR-607	CLIP-seq
MIRT2448945	hsa-miR-3149	CLIP-seq
MIRT2448946	hsa-miR-3713	CLIP-seq
MIRT969401	hsa-miR-4272	CLIP-seq
MIRT2437088	hsa-miR-4307	CLIP-seq
MIRT2448947	hsa-miR-4716-5p	CLIP-seq
MIRT969352	hsa-miR-105	CLIP-seq
MIRT1987254	hsa-miR-106a	CLIP-seq
MIRT1987255	hsa-miR-106b	CLIP-seq
MIRT969358	hsa-miR-125a-3p	CLIP-seq
MIRT2525409	hsa-miR-1265	CLIP-seq
MIRT2221736	hsa-miR-129-5p	CLIP-seq
MIRT2221737	hsa-miR-1302	CLIP-seq
MIRT2525410	hsa-miR-136	CLIP-seq
MIRT1987261	hsa-miR-142-5p	CLIP-seq
MIRT1987262	hsa-miR-150	CLIP-seq
MIRT1987263	hsa-miR-17	CLIP-seq
MIRT2221740	hsa-miR-1976	CLIP-seq
MIRT1987264	hsa-miR-208a	CLIP-seq
MIRT1987265	hsa-miR-208b	CLIP-seq
MIRT1987266	hsa-miR-20a	CLIP-seq
MIRT1987267	hsa-miR-20b	CLIP-seq
MIRT2437084	hsa-miR-23a	CLIP-seq
MIRT2437085	hsa-miR-23b	CLIP-seq
MIRT2437086	hsa-miR-23c	CLIP-seq
MIRT2221743	hsa-miR-2467-5p	CLIP-seq
MIRT1987272	hsa-miR-302a	CLIP-seq
MIRT1987273	hsa-miR-302b	CLIP-seq
MIRT1987274	hsa-miR-302c	CLIP-seq
MIRT1987275	hsa-miR-302d	CLIP-seq
MIRT1987276	hsa-miR-302e	CLIP-seq
MIRT1987277	hsa-miR-3117-5p	CLIP-seq
MIRT969379	hsa-miR-3121-3p	CLIP-seq
MIRT969381	hsa-miR-3150a-5p	CLIP-seq
MIRT969382	hsa-miR-3150b-5p	CLIP-seq
MIRT2221747	hsa-miR-3182	CLIP-seq
MIRT2221748	hsa-miR-3188	CLIP-seq
MIRT2525411	hsa-miR-325	CLIP-seq
MIRT2525412	hsa-miR-3658	CLIP-seq
MIRT2525413	hsa-miR-3667-5p	CLIP-seq
MIRT2437087	hsa-miR-3671	CLIP-seq
MIRT1987283	hsa-miR-372	CLIP-seq
MIRT1987284	hsa-miR-373	CLIP-seq
MIRT969394	hsa-miR-3919	CLIP-seq
MIRT969395	hsa-miR-3934	CLIP-seq
MIRT2221753	hsa-miR-3975	CLIP-seq
MIRT2221755	hsa-miR-4279	CLIP-seq
MIRT2221757	hsa-miR-4298	CLIP-seq
MIRT2437088	hsa-miR-4307	CLIP-seq
MIRT1987294	hsa-miR-4312	CLIP-seq
MIRT969407	hsa-miR-4454	CLIP-seq
MIRT2221761	hsa-miR-4662a-5p	CLIP-seq
MIRT2221762	hsa-miR-4663	CLIP-seq
MIRT2437089	hsa-miR-4666-5p	CLIP-seq
MIRT2525414	hsa-miR-4699-3p	CLIP-seq
MIRT2221763	hsa-miR-4722-3p	CLIP-seq
MIRT1987306	hsa-miR-4731-5p	CLIP-seq
MIRT1987307	hsa-miR-4740-3p	CLIP-seq
MIRT969422	hsa-miR-4756-3p	CLIP-seq
MIRT1987308	hsa-miR-4757-5p	CLIP-seq
MIRT2525415	hsa-miR-4760-5p	CLIP-seq
MIRT969425	hsa-miR-4763-5p	CLIP-seq
MIRT2221768	hsa-miR-4803	CLIP-seq
MIRT2221769	hsa-miR-485-5p	CLIP-seq
MIRT1987314	hsa-miR-488	CLIP-seq
MIRT1987315	hsa-miR-498	CLIP-seq
MIRT1987316	hsa-miR-499-5p	CLIP-seq
MIRT1987319	hsa-miR-512-3p	CLIP-seq
MIRT1987323	hsa-miR-519d	CLIP-seq
MIRT1987324	hsa-miR-520a-3p	CLIP-seq
MIRT1987325	hsa-miR-520b	CLIP-seq
MIRT1987326	hsa-miR-520c-3p	CLIP-seq
MIRT1987327	hsa-miR-520d-3p	CLIP-seq
MIRT1987328	hsa-miR-520e	CLIP-seq
MIRT1987329	hsa-miR-520g	CLIP-seq
MIRT1987330	hsa-miR-520h	CLIP-seq
MIRT2525416	hsa-miR-548m	CLIP-seq
MIRT2525417	hsa-miR-550b	CLIP-seq
MIRT2221771	hsa-miR-562	CLIP-seq
MIRT2525418	hsa-miR-574-3p	CLIP-seq
MIRT1987332	hsa-miR-577	CLIP-seq
MIRT2525419	hsa-miR-591	CLIP-seq
MIRT969450	hsa-miR-595	CLIP-seq
MIRT2437090	hsa-miR-607	CLIP-seq
MIRT2525420	hsa-miR-610	CLIP-seq
MIRT2525421	hsa-miR-628-3p	CLIP-seq
MIRT969453	hsa-miR-648	CLIP-seq
MIRT969456	hsa-miR-764	CLIP-seq
MIRT1987334	hsa-miR-93	CLIP-seq
MIRT969352	hsa-miR-105	CLIP-seq
MIRT1987254	hsa-miR-106a	CLIP-seq
MIRT1987255	hsa-miR-106b	CLIP-seq
MIRT969358	hsa-miR-125a-3p	CLIP-seq
MIRT2525409	hsa-miR-1265	CLIP-seq
MIRT2221737	hsa-miR-1302	CLIP-seq
MIRT2525410	hsa-miR-136	CLIP-seq
MIRT1987261	hsa-miR-142-5p	CLIP-seq
MIRT1987262	hsa-miR-150	CLIP-seq
MIRT1987263	hsa-miR-17	CLIP-seq
MIRT2680283	hsa-miR-188-5p	CLIP-seq
MIRT2221740	hsa-miR-1976	CLIP-seq
MIRT1987264	hsa-miR-208a	CLIP-seq
MIRT1987265	hsa-miR-208b	CLIP-seq
MIRT1987266	hsa-miR-20a	CLIP-seq
MIRT1987267	hsa-miR-20b	CLIP-seq
MIRT2437084	hsa-miR-23a	CLIP-seq
MIRT2437085	hsa-miR-23b	CLIP-seq
MIRT2437086	hsa-miR-23c	CLIP-seq
MIRT2221743	hsa-miR-2467-5p	CLIP-seq
MIRT1987272	hsa-miR-302a	CLIP-seq
MIRT1987273	hsa-miR-302b	CLIP-seq
MIRT1987274	hsa-miR-302c	CLIP-seq
MIRT1987275	hsa-miR-302d	CLIP-seq
MIRT1987276	hsa-miR-302e	CLIP-seq
MIRT1987277	hsa-miR-3117-5p	CLIP-seq
MIRT969379	hsa-miR-3121-3p	CLIP-seq
MIRT2221747	hsa-miR-3182	CLIP-seq
MIRT2221748	hsa-miR-3188	CLIP-seq
MIRT2525412	hsa-miR-3658	CLIP-seq
MIRT2525413	hsa-miR-3667-5p	CLIP-seq
MIRT2437087	hsa-miR-3671	CLIP-seq
MIRT1987283	hsa-miR-372	CLIP-seq
MIRT1987284	hsa-miR-373	CLIP-seq
MIRT969394	hsa-miR-3919	CLIP-seq
MIRT969395	hsa-miR-3934	CLIP-seq
MIRT2221753	hsa-miR-3975	CLIP-seq
MIRT2221755	hsa-miR-4279	CLIP-seq
MIRT2221757	hsa-miR-4298	CLIP-seq
MIRT2437088	hsa-miR-4307	CLIP-seq
MIRT1987294	hsa-miR-4312	CLIP-seq
MIRT969407	hsa-miR-4454	CLIP-seq
MIRT2221761	hsa-miR-4662a-5p	CLIP-seq
MIRT2221762	hsa-miR-4663	CLIP-seq
MIRT2437089	hsa-miR-4666-5p	CLIP-seq
MIRT2525414	hsa-miR-4699-3p	CLIP-seq
MIRT2221763	hsa-miR-4722-3p	CLIP-seq
MIRT1987306	hsa-miR-4731-5p	CLIP-seq
MIRT1987307	hsa-miR-4740-3p	CLIP-seq
MIRT969422	hsa-miR-4756-3p	CLIP-seq
MIRT1987308	hsa-miR-4757-5p	CLIP-seq
MIRT2525415	hsa-miR-4760-5p	CLIP-seq
MIRT969425	hsa-miR-4763-5p	CLIP-seq
MIRT2221768	hsa-miR-4803	CLIP-seq
MIRT2221769	hsa-miR-485-5p	CLIP-seq
MIRT1987315	hsa-miR-498	CLIP-seq
MIRT1987316	hsa-miR-499-5p	CLIP-seq
MIRT1987319	hsa-miR-512-3p	CLIP-seq
MIRT1987323	hsa-miR-519d	CLIP-seq
MIRT1987324	hsa-miR-520a-3p	CLIP-seq
MIRT1987325	hsa-miR-520b	CLIP-seq
MIRT1987326	hsa-miR-520c-3p	CLIP-seq
MIRT1987327	hsa-miR-520d-3p	CLIP-seq
MIRT1987328	hsa-miR-520e	CLIP-seq
MIRT1987329	hsa-miR-520g	CLIP-seq
MIRT1987330	hsa-miR-520h	CLIP-seq
MIRT2525417	hsa-miR-550b	CLIP-seq
MIRT2525418	hsa-miR-574-3p	CLIP-seq
MIRT1987332	hsa-miR-577	CLIP-seq
MIRT2525419	hsa-miR-591	CLIP-seq
MIRT969450	hsa-miR-595	CLIP-seq
MIRT2437090	hsa-miR-607	CLIP-seq
MIRT2525420	hsa-miR-610	CLIP-seq
MIRT969453	hsa-miR-648	CLIP-seq
MIRT969456	hsa-miR-764	CLIP-seq
MIRT1987334	hsa-miR-93	CLIP-seq

Show/Hide all(31)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	19240031, 21343306, 22119785, 30021884, 30352685, 33961781
GO:0005783	Component	Endoplasmic reticulum	IDA
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IBA
GO:0005789	Component	Endoplasmic reticulum membrane	IDA	16835267, 19240031
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	TAS
GO:0005829	Component	Cytosol	IDA
GO:0005886	Component	Plasma membrane	IDA
GO:0005886	Component	Plasma membrane	TAS
GO:0006629	Process	Lipid metabolic process	IEA
GO:0008202	Process	Steroid metabolic process	IEA
GO:0008203	Process	Cholesterol metabolic process	IEA
GO:0015485	Function	Cholesterol binding	IBA
GO:0016020	Component	Membrane	IEA
GO:0031625	Function	Ubiquitin protein ligase binding	IEA
GO:0031625	Function	Ubiquitin protein ligase binding	IPI	24019521
GO:0032933	Process	SREBP signaling pathway	IBA
GO:0032933	Process	SREBP signaling pathway	IEA
GO:0032933	Process	SREBP signaling pathway	IMP	24217618
GO:0032991	Component	Protein-containing complex	IDA	18468998
GO:0032991	Component	Protein-containing complex	IEA
GO:0036503	Process	ERAD pathway	IDA	19240031
GO:0036503	Process	ERAD pathway	IEA
GO:0045121	Component	Membrane raft	IDA	25204797
GO:0045121	Component	Membrane raft	NAS	34572057
GO:0045540	Process	Regulation of cholesterol biosynthetic process	IDA	24217618
GO:0045541	Process	Negative regulation of cholesterol biosynthetic process	IEA
GO:0045541	Process	Negative regulation of cholesterol biosynthetic process	IMP	24217618
GO:0045717	Process	Negative regulation of fatty acid biosynthetic process	IEA
GO:0045717	Process	Negative regulation of fatty acid biosynthetic process	IMP	24217618

MIM	HGNC	e!Ensembl
611605	1356	ENSG00000147475

Protein

UniProt ID

O94905

Protein name

Erlin-2 (Endoplasmic reticulum lipid raft-associated protein 2) (Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2) (SPFH domain-containing protein 2)

Protein function

Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs) such as ITPR1 (PubMed:17502376, PubMed:19240031). Promotes sterol-accelerated ERAD of

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01145	Band_7	24 → 216	SPFH domain / Band 7 family	Family

Tissue specificity

TISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:10449903}.

Sequence

MAQLGAVVAVASSFFCASLFSAVHKIEEGHIGVYYRGGALLTSTSGPGFHLMLPFITSYK
SVQTTLQTDEVKNVPCGTSGGVMIYFDRIEVVNFLVPNAVYDIVKNYTADYDKALIFNKI
HHELNQFCSVHTLQEVYIELFDQIDENLKLALQQDLTSMAPGLVIQAVRVTKPNIPEAIR
RNYELMESEKTKLLIAAQKQKVVEKEAETERKKALIEAEKVAQVAEITYGQKVMEKETEK
KISEIEDAAFLAREKAKADAECYTAMKIAEANKLKLTPEYLQLMKYKAIASNSKIYFGKD
IPNMFMDSAGSVSKQFEGLADKLSFGLEDEPLETATKEN

Sequence length

339

Interactions

View interactions

Show/Hide Causal Diseases (2)

Disease merge term	Disease name	dbSNP ID	References
Causal Diseases caused by PATHOGENIC or LIKELY PATHOGENIC variants from ClinVar only
Hereditary spastic paraplegia	Hereditary spastic paraplegia, Hereditary spastic paraplegia 18	rs1802811311, rs587776893, rs398123002, rs1554517382	N/A
Spastic Paraplegia	spastic paraplegia, Spastic paraplegia 18a, autosomal dominant	rs1554517327, rs1585896928, rs1802811311, rs1052410160	N/A

Show/Hide Unknown Diseases (3)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disability-Motor Dysfunction-Multiple Joint Contractures Syndrome	recessive intellectual disability-motor dysfunction-multiple joint contractures syndrome	N/A	N/A	GenCC
Lateral Sclerosis	juvenile primary lateral sclerosis	N/A	N/A	GenCC
Oligodendroglioma	Oligodendroglioma	N/A	N/A	GWAS

Show/Hide Text Mining Associations (15)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Adenocarcinoma of Lung	Associate	33424830
Astrocytoma	Associate	32883232
Breast Neoplasms	Associate	22681620, 37831636
Breast Neoplasms	Stimulate	22690709
Carcinogenesis	Associate	22681620
Carcinoma Hepatocellular	Associate	22690709
Carcinoma Squamous Cell	Associate	37575065
Hereditary Breast and Ovarian Cancer Syndrome	Associate	22681620
Liver Neoplasms	Associate	34946825
Lymphatic Metastasis	Stimulate	33424830
Neoplasm Metastasis	Associate	37831636
Neoplasms	Associate	22690709, 33424830
Neurodegenerative Diseases	Associate	31874412
Spastic Paraplegia 18 Autosomal Recessive	Associate	32094424
Spastic Paraplegia Hereditary	Associate	21796390, 32094424, 40225166

ERLIN2 (ER lipid raft associated 2)