Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs Transcription factors Other IDs Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	2064
Gene name Gene Name - the full gene name approved by the HGNC.	Erb-b2 receptor tyrosine kinase 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	ERBB2
Synonyms (NCBI Gene) Gene synonyms aliases	CD340, HER-2, HER-2/neu, HER2, MLN 19, MLN-19, NEU, NGL, TKR1, VSCN2, c-ERB-2, c-ERB2, p185(erbB2)
Disease Acronyms (UniProt) Disease acronyms from UniProt database	VSCN2
Chromosome Chromosome number	17
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	17q12
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-boun

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SNP ID	Visualize variation	Clinical significance	Consequence
rs121913468	G>A,C,T	Likely-pathogenic, pathogenic	Coding sequence variant, missense variant, non coding transcript variant, genic downstream transcript variant
rs121913469	TT>CC	Pathogenic, likely-pathogenic	Coding sequence variant, missense variant, non coding transcript variant, genic downstream transcript variant
rs121913470	T>C,G	Likely-pathogenic	Coding sequence variant, missense variant, non coding transcript variant, genic downstream transcript variant
rs1057519787	G>A,C	Likely-pathogenic	Coding sequence variant, non coding transcript variant, missense variant
rs1057519816	C>A,T	Likely-pathogenic	Coding sequence variant, non coding transcript variant, missense variant
rs1057519862	G>A	Likely-pathogenic, not-provided	Coding sequence variant, genic downstream transcript variant, non coding transcript variant, missense variant
rs1057519890	T>A	Likely-pathogenic	Coding sequence variant, genic downstream transcript variant, non coding transcript variant, missense variant
rs1131692241	TGAGGGAAAACACAT>-	Pathogenic	Coding sequence variant, genic downstream transcript variant, non coding transcript variant, inframe deletion

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miRTarBase ID	miRNA	Experiments	Reference
MIRT004318	hsa-miR-21-5p	qRT-PCR, Western blot	19419954
MIRT002939	hsa-miR-125b-5p	Western blot	19825990
MIRT005118	hsa-miR-125a-5p	Luciferase reporter assay, Northern blot, qRT-PCR, Western blot	17110380
MIRT005118	hsa-miR-125a-5p	Luciferase reporter assay, Northern blot, qRT-PCR, Western blot	17110380
MIRT002939	hsa-miR-125b-5p	Luciferase reporter assay, Northern blot, qRT-PCR, Western blot	17110380
MIRT002939	hsa-miR-125b-5p	Luciferase reporter assay, Northern blot, qRT-PCR, Western blot	17110380
MIRT000037	hsa-miR-548d-3p	Luciferase reporter assay	19486885
MIRT000037	hsa-miR-548d-3p	Luciferase reporter assay	19486885
MIRT000036	hsa-miR-559	Luciferase reporter assay	19486885
MIRT000036	hsa-miR-559	Luciferase reporter assay	19486885
MIRT005805	hsa-miR-331-3p	Luciferase reporter assay, Microarray, Western blot	20864407
MIRT002939	hsa-miR-125b-5p	Luciferase reporter assay, Microarray, Western blot	20864407
MIRT005118	hsa-miR-125a-5p	Luciferase reporter assay	21220473
MIRT005118	hsa-miR-125a-5p	Luciferase reporter assay	21220473
MIRT006982	hsa-miR-205-5p	qRT-PCR, Western blot	21787752
MIRT006982	hsa-miR-205-5p	qRT-PCR, Western blot	21787752
MIRT007152	hsa-miR-199b-5p	Luciferase reporter assay, qRT-PCR, Western blot	23296799
MIRT007152	hsa-miR-199b-5p	Luciferase reporter assay, qRT-PCR, Western blot	23296799
MIRT007265	hsa-miR-199a-5p	Western blot	23437196
MIRT000037	hsa-miR-548d-3p	Reporter assay;Other	19486885
MIRT000036	hsa-miR-559	Reporter assay;Other	19486885
MIRT005118	hsa-miR-125a-5p	Western blot	17110380
MIRT005118	hsa-miR-125a-5p	Northern blot	17110380
MIRT002939	hsa-miR-125b-5p	Western blot	19825990
MIRT023179	hsa-miR-124-3p	Microarray	18668037
MIRT043637	hsa-miR-326	CLASH	23622248
MIRT002939	hsa-miR-125b-5p	Luciferase reporter assay, Western blot	22460089
MIRT007265	hsa-miR-199a-5p	Immunoblot, Immunohistochemistry, Luciferase reporter assay, qRT-PCR	23146892
MIRT053780	hsa-miR-375	Luciferase reporter assay, qRT-PCR, Western blot	24926380
MIRT053780	hsa-miR-375	Luciferase reporter assay, qRT-PCR, Western blot	24926380
MIRT054130	hsa-miR-25-3p	Luciferase reporter assay, qRT-PCR, Western blot	25043310
MIRT054130	hsa-miR-25-3p	Luciferase reporter assay, qRT-PCR, Western blot	25043310
MIRT005118	hsa-miR-125a-5p	Western blot, qRT-PCR	23519125
MIRT005118	hsa-miR-125a-5p	Western blot, qRT-PCR	23519125
MIRT438507	hsa-miR-134-5p	Luciferase reporter assay	24148764
MIRT438506	hsa-miR-193a-3p	Luciferase reporter assay	24148764
MIRT438505	hsa-miR-193a-5p	Luciferase reporter assay	24148764
MIRT005805	hsa-miR-331-3p	Luciferase reporter assay	24148764
MIRT438504	hsa-miR-323b-5p	Luciferase reporter assay	24148764
MIRT438503	hsa-miR-498	Luciferase reporter assay	24148764
MIRT438502	hsa-miR-541-3p	Luciferase reporter assay	24148764
MIRT438501	hsa-miR-552-3p	Luciferase reporter assay	24148764
MIRT005805	hsa-miR-331-3p	Flow, Immunohistochemistry, Luciferase reporter assay, qRT-PCR, Western blot	24775712
MIRT438507	hsa-miR-134-5p	Luciferase reporter assay	24148764
MIRT438506	hsa-miR-193a-3p	Luciferase reporter assay	24148764
MIRT438505	hsa-miR-193a-5p	Luciferase reporter assay	24148764
MIRT005805	hsa-miR-331-3p	Luciferase reporter assay	24148764
MIRT438504	hsa-miR-323b-5p	Luciferase reporter assay	24148764
MIRT438503	hsa-miR-498	Luciferase reporter assay	24148764
MIRT438502	hsa-miR-541-3p	Luciferase reporter assay	24148764
MIRT438501	hsa-miR-552-3p	Luciferase reporter assay	24148764
MIRT005805	hsa-miR-331-3p	Flow, Immunohistochemistry, Luciferase reporter assay, qRT-PCR, Western blot	24775712
MIRT608206	hsa-miR-4506	HITS-CLIP	24906430
MIRT608205	hsa-miR-888-3p	HITS-CLIP	24906430
MIRT608204	hsa-miR-7845-5p	HITS-CLIP	24906430
MIRT608203	hsa-miR-4464	HITS-CLIP	24906430
MIRT608201	hsa-miR-4748	HITS-CLIP	24906430
MIRT608202	hsa-miR-329-5p	HITS-CLIP	24906430
MIRT608200	hsa-miR-211-3p	HITS-CLIP	24906430
MIRT608199	hsa-miR-4270	HITS-CLIP	24906430
MIRT608198	hsa-miR-4441	HITS-CLIP	24906430
MIRT608197	hsa-miR-6754-5p	HITS-CLIP	24906430
MIRT608196	hsa-miR-6072	HITS-CLIP	24906430
MIRT608195	hsa-miR-6891-3p	HITS-CLIP	24906430
MIRT608194	hsa-miR-6734-3p	HITS-CLIP	24906430
MIRT608193	hsa-miR-3667-3p	HITS-CLIP	24906430
MIRT608191	hsa-miR-4315	HITS-CLIP	24906430
MIRT608192	hsa-miR-146a-3p	HITS-CLIP	24906430
MIRT608190	hsa-miR-301a-5p	HITS-CLIP	24906430
MIRT608189	hsa-miR-301b-5p	HITS-CLIP	24906430
MIRT608188	hsa-miR-3921	HITS-CLIP	24906430
MIRT608187	hsa-miR-4653-5p	HITS-CLIP	24906430
MIRT608186	hsa-miR-4427	HITS-CLIP	24906430
MIRT608185	hsa-miR-5187-3p	HITS-CLIP	24906430
MIRT608184	hsa-miR-4680-3p	HITS-CLIP	24906430
MIRT608183	hsa-miR-6730-3p	HITS-CLIP	24906430
MIRT608182	hsa-miR-4790-3p	HITS-CLIP	24906430
MIRT608181	hsa-miR-1254	HITS-CLIP	24906430
MIRT608180	hsa-miR-3116	HITS-CLIP	24906430
MIRT608179	hsa-miR-3140-3p	HITS-CLIP	24906430
MIRT608177	hsa-miR-486-3p	HITS-CLIP	24906430
MIRT608178	hsa-miR-6795-5p	HITS-CLIP	24906430
MIRT608176	hsa-miR-6887-5p	HITS-CLIP	24906430
MIRT608175	hsa-miR-328-5p	HITS-CLIP	24906430
MIRT608174	hsa-miR-6885-5p	HITS-CLIP	24906430
MIRT608173	hsa-miR-593-3p	HITS-CLIP	24906430
MIRT076993	hsa-miR-4326	HITS-CLIP	24906430
MIRT608172	hsa-miR-2116-5p	HITS-CLIP	24906430
MIRT608171	hsa-miR-22-5p	HITS-CLIP	24906430
MIRT608170	hsa-miR-3127-5p	HITS-CLIP	24906430
MIRT608169	hsa-miR-6868-3p	HITS-CLIP	24906430
MIRT608168	hsa-miR-4790-5p	HITS-CLIP	24906430
MIRT608167	hsa-miR-7109-5p	HITS-CLIP	24906430
MIRT608166	hsa-miR-4273	HITS-CLIP	24906430
MIRT608165	hsa-miR-7156-5p	HITS-CLIP	24906430
MIRT608164	hsa-miR-4677-5p	HITS-CLIP	24906430
MIRT076987	hsa-miR-670-3p	HITS-CLIP	24906430
MIRT053780	hsa-miR-375	HITS-CLIP	24906430
MIRT608163	hsa-miR-6739-3p	HITS-CLIP	24906430
MIRT002939	hsa-miR-125b-5p	qRT-PCR, Luciferase reporter assay, Immunoblot, Western blot	25388283
MIRT002939	hsa-miR-125b-5p	qRT-PCR, Luciferase reporter assay, Immunoblot, Western blot	25388283
MIRT002939	hsa-miR-125b-5p	qRT-PCR, Luciferase reporter assay, Immunoblot, Western blot	25388283
MIRT002939	hsa-miR-125b-5p	qRT-PCR, Luciferase reporter assay, Immunoblot, Western blot	25388283
MIRT002939	hsa-miR-125b-5p	qRT-PCR, Luciferase reporter assay, Immunoblot, Western blot	25388283
MIRT002939	hsa-miR-125b-5p	qRT-PCR, Luciferase reporter assay, Immunoblot, Western blot	25388283
MIRT002939	hsa-miR-125b-5p	qRT-PCR, Luciferase reporter assay, Immunoblot, Western blot	25388283
MIRT002939	hsa-miR-125b-5p	qRT-PCR, Luciferase reporter assay, Immunoblot, Western blot	25388283
MIRT002939	hsa-miR-125b-5p	qRT-PCR, Luciferase reporter assay, Immunoblot, Western blot	25388283
MIRT002939	hsa-miR-125b-5p	qRT-PCR, Luciferase reporter assay, Immunoblot, Western blot	25388283
MIRT002939	hsa-miR-125b-5p	qRT-PCR, Luciferase reporter assay, Immunoblot, Western blot	25388283
MIRT053780	hsa-miR-375	Flow, qRT-PCR, Western blot	26893657
MIRT005805	hsa-miR-331-3p	Luciferase reporter assay, Western blot	26718987
MIRT096897	hsa-miR-130b-3p	Luciferase reporter assay	26316103
MIRT006982	hsa-miR-205-5p	Luciferase reporter assay, qRT-PCR, Western blot	26181203
MIRT006982	hsa-miR-205-5p	Luciferase reporter assay, qRT-PCR, Western blot	26181203
MIRT002939	hsa-miR-125b-5p	Luciferase reporter assay, Western blot	26966351
MIRT002939	hsa-miR-125b-5p	Luciferase reporter assay, Western blot	26966351
MIRT002939	hsa-miR-125b-5p	Luciferase reporter assay, Western blot	26966351
MIRT002939	hsa-miR-125b-5p	Luciferase reporter assay, Western blot	26966351
MIRT002939	hsa-miR-125b-5p	Luciferase reporter assay, Western blot	26966351
MIRT002939	hsa-miR-125b-5p	Luciferase reporter assay, Western blot	26966351
MIRT002939	hsa-miR-125b-5p	Luciferase reporter assay, Western blot	26966351
MIRT002939	hsa-miR-125b-5p	Luciferase reporter assay, Western blot	26966351
MIRT002939	hsa-miR-125b-5p	Luciferase reporter assay, Western blot	26966351
MIRT002939	hsa-miR-125b-5p	Luciferase reporter assay, Western blot	26966351
MIRT002939	hsa-miR-125b-5p	Luciferase reporter assay, Western blot	26966351
MIRT002939	hsa-miR-125b-5p	Luciferase reporter assay, Western blot	26966351
MIRT002939	hsa-miR-125b-5p	Luciferase reporter assay, Western blot	26966351
MIRT002939	hsa-miR-125b-5p	Luciferase reporter assay, Western blot	26966351
MIRT002939	hsa-miR-125b-5p	Luciferase reporter assay, Western blot	26966351
MIRT002939	hsa-miR-125b-5p	Luciferase reporter assay	26544868
MIRT002939	hsa-miR-125b-5p	Luciferase reporter assay	26544868
MIRT002939	hsa-miR-125b-5p	Luciferase reporter assay	26544868
MIRT002939	hsa-miR-125b-5p	Luciferase reporter assay	26544868
MIRT002939	hsa-miR-125b-5p	Luciferase reporter assay	26544868
MIRT002939	hsa-miR-125b-5p	Luciferase reporter assay	26544868
MIRT005118	hsa-miR-125a-5p	Luciferase reporter assay, qRT-PCR, Western blot	25833836
MIRT005118	hsa-miR-125a-5p	Luciferase reporter assay, qRT-PCR, Western blot	25833836
MIRT005118	hsa-miR-125a-5p	Luciferase reporter assay, qRT-PCR, Western blot	25833836
MIRT005118	hsa-miR-125a-5p	Luciferase reporter assay, qRT-PCR, Western blot	25833836
MIRT005118	hsa-miR-125a-5p	Luciferase reporter assay, qRT-PCR, Western blot	25833836
MIRT005118	hsa-miR-125a-5p	Luciferase reporter assay, qRT-PCR, Western blot	25833836
MIRT005118	hsa-miR-125a-5p	Luciferase reporter assay, qRT-PCR, Western blot	25833836
MIRT005118	hsa-miR-125a-5p	Luciferase reporter assay, qRT-PCR, Western blot	25833836
MIRT005118	hsa-miR-125a-5p	Luciferase reporter assay, qRT-PCR, Western blot	25833836
MIRT005118	hsa-miR-125a-5p	Luciferase reporter assay, qRT-PCR, Western blot	25833836
MIRT005118	hsa-miR-125a-5p	Luciferase reporter assay, qRT-PCR, Western blot	25833836
MIRT005118	hsa-miR-125a-5p	Luciferase reporter assay, qRT-PCR, Western blot	25833836
MIRT002939	hsa-miR-125b-5p	Luciferase reporter assay, qRT-PCR, Western blot	25833836
MIRT002939	hsa-miR-125b-5p	Luciferase reporter assay, qRT-PCR, Western blot	25833836
MIRT005118	hsa-miR-125a-5p	Luciferase reporter assay, qRT-PCR, Western blot	25833836
MIRT005118	hsa-miR-125a-5p	Luciferase reporter assay, qRT-PCR, Western blot	25833836
MIRT002939	hsa-miR-125b-5p	Luciferase reporter assay, qRT-PCR, Western blot	25833836
MIRT002939	hsa-miR-125b-5p	Luciferase reporter assay, qRT-PCR, Western blot	25833836
MIRT002939	hsa-miR-125b-5p	Luciferase reporter assay, qRT-PCR, Western blot	25833836
MIRT002939	hsa-miR-125b-5p	Luciferase reporter assay, qRT-PCR, Western blot	25833836
MIRT005118	hsa-miR-125a-5p	Luciferase reporter assay, qRT-PCR, Western blot	25833836
MIRT005118	hsa-miR-125a-5p	Luciferase reporter assay, qRT-PCR, Western blot	25833836
MIRT438505	hsa-miR-193a-5p	Luciferase reporter assay	27203740
MIRT438505	hsa-miR-193a-5p	Luciferase reporter assay	27203740
MIRT608192	hsa-miR-146a-3p	Western blotting, Immunofluorescence, qRT-PCR, Flow cytometry, ELISA	33447879
MIRT608184	hsa-miR-4680-3p	Western blotting, qRT-PCR	38191190
MIRT053780	hsa-miR-375	Luciferase reporter assay, Western blotting, qRT-PCR	34729115
MIRT755900	hsa-miR-449c-5p	Luciferase reporter assay, Western blotting, qRT-PCR	38351535
MIRT967800	hsa-miR-1197	CLIP-seq
MIRT967801	hsa-miR-1207-5p	CLIP-seq
MIRT967802	hsa-miR-1343	CLIP-seq
MIRT967803	hsa-miR-3117-3p	CLIP-seq
MIRT967804	hsa-miR-4292	CLIP-seq
MIRT967805	hsa-miR-4432	CLIP-seq
MIRT967806	hsa-miR-4713-5p	CLIP-seq
MIRT967807	hsa-miR-4720-5p	CLIP-seq
MIRT967808	hsa-miR-4736	CLIP-seq
MIRT967809	hsa-miR-4763-3p	CLIP-seq
MIRT967810	hsa-miR-4799-3p	CLIP-seq
MIRT967811	hsa-miR-548u	CLIP-seq
MIRT967812	hsa-miR-3152-5p	CLIP-seq
MIRT967813	hsa-miR-3911	CLIP-seq
MIRT967804	hsa-miR-4292	CLIP-seq
MIRT967814	hsa-miR-4434	CLIP-seq
MIRT967815	hsa-miR-4455	CLIP-seq
MIRT967816	hsa-miR-4516	CLIP-seq
MIRT967817	hsa-miR-4531	CLIP-seq
MIRT967806	hsa-miR-4713-5p	CLIP-seq
MIRT967818	hsa-miR-4796-3p	CLIP-seq
MIRT967819	hsa-miR-520g	CLIP-seq
MIRT967820	hsa-miR-520h	CLIP-seq
MIRT967821	hsa-miR-609	CLIP-seq
MIRT967822	hsa-miR-660	CLIP-seq
MIRT967813	hsa-miR-3911	CLIP-seq
MIRT967814	hsa-miR-4434	CLIP-seq
MIRT967815	hsa-miR-4455	CLIP-seq
MIRT967816	hsa-miR-4516	CLIP-seq
MIRT967817	hsa-miR-4531	CLIP-seq
MIRT967818	hsa-miR-4796-3p	CLIP-seq
MIRT967819	hsa-miR-520g	CLIP-seq
MIRT967820	hsa-miR-520h	CLIP-seq
MIRT967821	hsa-miR-609	CLIP-seq
MIRT1921591	hsa-miR-1296	CLIP-seq
MIRT1921592	hsa-miR-2116	CLIP-seq
MIRT1921593	hsa-miR-2909	CLIP-seq
MIRT1921594	hsa-miR-4287	CLIP-seq
MIRT1921595	hsa-miR-4512	CLIP-seq
MIRT1921596	hsa-miR-4685-3p	CLIP-seq
MIRT1921597	hsa-miR-593	CLIP-seq
MIRT1921597	hsa-miR-593	CLIP-seq
MIRT1921591	hsa-miR-1296	CLIP-seq
MIRT1921592	hsa-miR-2116	CLIP-seq
MIRT1921593	hsa-miR-2909	CLIP-seq
MIRT1921594	hsa-miR-4287	CLIP-seq
MIRT1921595	hsa-miR-4512	CLIP-seq
MIRT1921596	hsa-miR-4685-3p	CLIP-seq
MIRT1921597	hsa-miR-593	CLIP-seq
MIRT967801	hsa-miR-1207-5p	CLIP-seq
MIRT967809	hsa-miR-4763-3p	CLIP-seq
MIRT1986718	hsa-miR-1266	CLIP-seq
MIRT1921591	hsa-miR-1296	CLIP-seq
MIRT1986719	hsa-miR-1972	CLIP-seq
MIRT1921592	hsa-miR-2116	CLIP-seq
MIRT1921593	hsa-miR-2909	CLIP-seq
MIRT1986720	hsa-miR-3664-3p	CLIP-seq
MIRT1921594	hsa-miR-4287	CLIP-seq
MIRT967804	hsa-miR-4292	CLIP-seq
MIRT1921595	hsa-miR-4512	CLIP-seq
MIRT1986721	hsa-miR-4518	CLIP-seq
MIRT1986722	hsa-miR-4650-5p	CLIP-seq
MIRT1921596	hsa-miR-4685-3p	CLIP-seq
MIRT967806	hsa-miR-4713-5p	CLIP-seq
MIRT1921597	hsa-miR-593	CLIP-seq
MIRT967822	hsa-miR-660	CLIP-seq
MIRT967800	hsa-miR-1197	CLIP-seq
MIRT2221240	hsa-miR-1202	CLIP-seq
MIRT967801	hsa-miR-1207-5p	CLIP-seq
MIRT2221241	hsa-miR-1224-3p	CLIP-seq
MIRT2221242	hsa-miR-1224-5p	CLIP-seq
MIRT2221243	hsa-miR-1236	CLIP-seq
MIRT2221244	hsa-miR-1237	CLIP-seq
MIRT2221245	hsa-miR-1245b-5p	CLIP-seq
MIRT2221246	hsa-miR-1252	CLIP-seq
MIRT2221247	hsa-miR-125b	CLIP-seq
MIRT2221248	hsa-miR-1260	CLIP-seq
MIRT2221249	hsa-miR-1260b	CLIP-seq
MIRT1986718	hsa-miR-1266	CLIP-seq
MIRT2221250	hsa-miR-1280	CLIP-seq
MIRT2221251	hsa-miR-1292	CLIP-seq
MIRT1921591	hsa-miR-1296	CLIP-seq
MIRT2221252	hsa-miR-1299	CLIP-seq
MIRT967802	hsa-miR-1343	CLIP-seq
MIRT2221253	hsa-miR-1587	CLIP-seq
MIRT2221254	hsa-miR-1825	CLIP-seq
MIRT2221255	hsa-miR-1912	CLIP-seq
MIRT1986719	hsa-miR-1972	CLIP-seq
MIRT1921592	hsa-miR-2116	CLIP-seq
MIRT2221256	hsa-miR-2355-5p	CLIP-seq
MIRT1921593	hsa-miR-2909	CLIP-seq
MIRT2221257	hsa-miR-298	CLIP-seq
MIRT967803	hsa-miR-3117-3p	CLIP-seq
MIRT2221258	hsa-miR-3127-3p	CLIP-seq
MIRT2221259	hsa-miR-3130-5p	CLIP-seq
MIRT2221260	hsa-miR-3142	CLIP-seq
MIRT967812	hsa-miR-3152-5p	CLIP-seq
MIRT2221261	hsa-miR-3158-3p	CLIP-seq
MIRT2221262	hsa-miR-3192	CLIP-seq
MIRT2221263	hsa-miR-3194-5p	CLIP-seq
MIRT2221264	hsa-miR-3202	CLIP-seq
MIRT2221265	hsa-miR-320e	CLIP-seq
MIRT2221266	hsa-miR-3545-5p	CLIP-seq
MIRT2221267	hsa-miR-3652	CLIP-seq
MIRT2221268	hsa-miR-3654	CLIP-seq
MIRT1986720	hsa-miR-3664-3p	CLIP-seq
MIRT2221269	hsa-miR-3664-5p	CLIP-seq
MIRT2221270	hsa-miR-3688-5p	CLIP-seq
MIRT2221271	hsa-miR-378g	CLIP-seq
MIRT967813	hsa-miR-3911	CLIP-seq
MIRT2221272	hsa-miR-3918	CLIP-seq
MIRT2221273	hsa-miR-3972	CLIP-seq
MIRT1921594	hsa-miR-4287	CLIP-seq
MIRT2221274	hsa-miR-4290	CLIP-seq
MIRT967804	hsa-miR-4292	CLIP-seq
MIRT2221275	hsa-miR-4297	CLIP-seq
MIRT2221276	hsa-miR-4308	CLIP-seq
MIRT2221277	hsa-miR-4314	CLIP-seq
MIRT2221278	hsa-miR-4319	CLIP-seq
MIRT2221279	hsa-miR-4430	CLIP-seq
MIRT967805	hsa-miR-4432	CLIP-seq
MIRT967814	hsa-miR-4434	CLIP-seq
MIRT967815	hsa-miR-4455	CLIP-seq
MIRT2221280	hsa-miR-4471	CLIP-seq
MIRT2221281	hsa-miR-4476	CLIP-seq
MIRT2221282	hsa-miR-4482	CLIP-seq
MIRT2221283	hsa-miR-4492	CLIP-seq
MIRT2221284	hsa-miR-4498	CLIP-seq
MIRT1921595	hsa-miR-4512	CLIP-seq
MIRT967816	hsa-miR-4516	CLIP-seq
MIRT1986721	hsa-miR-4518	CLIP-seq
MIRT2221285	hsa-miR-4530	CLIP-seq
MIRT967817	hsa-miR-4531	CLIP-seq
MIRT2221286	hsa-miR-4533	CLIP-seq
MIRT2221287	hsa-miR-4642	CLIP-seq
MIRT2221288	hsa-miR-4646-5p	CLIP-seq
MIRT1986722	hsa-miR-4650-5p	CLIP-seq
MIRT2221289	hsa-miR-4656	CLIP-seq
MIRT2221290	hsa-miR-4675	CLIP-seq
MIRT1921596	hsa-miR-4685-3p	CLIP-seq
MIRT2221291	hsa-miR-4694-3p	CLIP-seq
MIRT967806	hsa-miR-4713-5p	CLIP-seq
MIRT967807	hsa-miR-4720-5p	CLIP-seq
MIRT2221292	hsa-miR-4732-3p	CLIP-seq
MIRT2221293	hsa-miR-4734	CLIP-seq
MIRT967808	hsa-miR-4736	CLIP-seq
MIRT2221294	hsa-miR-4741	CLIP-seq
MIRT2221295	hsa-miR-4751	CLIP-seq
MIRT2221296	hsa-miR-4754	CLIP-seq
MIRT967809	hsa-miR-4763-3p	CLIP-seq
MIRT2221297	hsa-miR-4795-5p	CLIP-seq
MIRT967818	hsa-miR-4796-3p	CLIP-seq
MIRT967810	hsa-miR-4799-3p	CLIP-seq
MIRT2221298	hsa-miR-485-5p	CLIP-seq
MIRT2221299	hsa-miR-512-3p	CLIP-seq
MIRT2221300	hsa-miR-518a-5p	CLIP-seq
MIRT2221301	hsa-miR-520d-5p	CLIP-seq
MIRT967819	hsa-miR-520g	CLIP-seq
MIRT967820	hsa-miR-520h	CLIP-seq
MIRT2221302	hsa-miR-524-5p	CLIP-seq
MIRT2221303	hsa-miR-527	CLIP-seq
MIRT2221304	hsa-miR-532-3p	CLIP-seq
MIRT2221305	hsa-miR-544b	CLIP-seq
MIRT967811	hsa-miR-548u	CLIP-seq
MIRT1921597	hsa-miR-593	CLIP-seq
MIRT967821	hsa-miR-609	CLIP-seq
MIRT2221306	hsa-miR-642b	CLIP-seq
MIRT2221307	hsa-miR-657	CLIP-seq
MIRT967822	hsa-miR-660	CLIP-seq
MIRT2221308	hsa-miR-670	CLIP-seq
MIRT2221309	hsa-miR-711	CLIP-seq
MIRT2221310	hsa-miR-762	CLIP-seq
MIRT2221311	hsa-miR-875-3p	CLIP-seq
MIRT2221312	hsa-miR-922	CLIP-seq
MIRT1921592	hsa-miR-2116	CLIP-seq
MIRT967813	hsa-miR-3911	CLIP-seq
MIRT967814	hsa-miR-4434	CLIP-seq
MIRT967815	hsa-miR-4455	CLIP-seq
MIRT967816	hsa-miR-4516	CLIP-seq
MIRT967817	hsa-miR-4531	CLIP-seq
MIRT967818	hsa-miR-4796-3p	CLIP-seq
MIRT967819	hsa-miR-520g	CLIP-seq
MIRT967820	hsa-miR-520h	CLIP-seq
MIRT1921597	hsa-miR-593	CLIP-seq
MIRT967821	hsa-miR-609	CLIP-seq

Transcription factors

Show/Hide all(33)

Transcription factor	Regulation	Reference
AR	Activation	21613411
AR	Unknown	21741601
ATF1	Unknown	10698518
ATF7	Unknown	10698518
CREB1	Unknown	10698518
DENND4A	Repression	23421821
ELF1	Unknown	7914192
ELK1	Unknown	7914192
EP300	Unknown	9045619
ETV4	Repression	10655108;15235125;16632435;17168666
ETV4	Unknown	7914192
FOXP3	Unknown	17570480
GABPA	Unknown	7914192
GATA4	Repression	19276186
JUND	Unknown	10698518
MYB	Unknown	2577338
NCOA3	Unknown	10991938
PAX2	Unknown	10991938
PGR	Repression	18483177
PURA	Unknown	22899247
SP1	Activation	12802284;22553354
SP3	Activation	22553354
SP4	Activation	22553354
TFAP2A	Unknown	10698518;15870067;18218085;22577344
TFAP2B	Unknown	10645007
TFAP2C	Unknown	10645007
VDR	Unknown	10765127
XRCC5	Unknown	22899247
XRCC6	Unknown	22899247
YBX1	Activation	19648825
YBX1	Unknown	20838384
YY1	Activation	19435870
YY1	Unknown	15870067;18218085

Show/Hide all(77)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000165	Process	MAPK cascade	TAS
GO:0001042	Function	RNA polymerase I core binding	IDA	21555369
GO:0001934	Process	Positive regulation of protein phosphorylation	ISS
GO:0004713	Function	Protein tyrosine kinase activity	IDA	7556068, 12000754
GO:0004713	Function	Protein tyrosine kinase activity	IGI	7556068
GO:0004713	Function	Protein tyrosine kinase activity	TAS
GO:0004714	Function	Transmembrane receptor protein tyrosine kinase activity	IBA	21873635
GO:0004714	Function	Transmembrane receptor protein tyrosine kinase activity	IDA	7514177
GO:0004888	Function	Transmembrane signaling receptor activity	IDA	7514177
GO:0005515	Function	Protein binding	IPI	7592681, 9079677, 9705354, 10572067, 10805725, 11940572, 12061724, 12122014, 12975581, 15282549, 15345710, 15657067, 16273093, 16314522, 16516204, 16767099, 16843263, 17148612, 17426253, 18719096, 19167335, 19372587, 19411071, 19650109, 19933325, 20010870, 20227043, 20558745, 206500
GO:0005524	Function	ATP binding	IEA
GO:0005634	Component	Nucleus	IDA	16314522, 21555369
GO:0005769	Component	Early endosome	IEA
GO:0005829	Component	Cytosol	IDA
GO:0005886	Component	Plasma membrane	IDA	20010870
GO:0005886	Component	Plasma membrane	NAS	12000754
GO:0005886	Component	Plasma membrane	TAS
GO:0005887	Component	Integral component of plasma membrane	IBA	21873635
GO:0006357	Process	Regulation of transcription by RNA polymerase II	TAS
GO:0006468	Process	Protein phosphorylation	TAS	10851066
GO:0007165	Process	Signal transduction	IDA	10572067
GO:0007166	Process	Cell surface receptor signaling pathway	IDA	9685399
GO:0007167	Process	Enzyme linked receptor protein signaling pathway	TAS	9590694
GO:0007169	Process	Transmembrane receptor protein tyrosine kinase signaling pathway	IBA	21873635
GO:0007169	Process	Transmembrane receptor protein tyrosine kinase signaling pathway	IDA	7514177
GO:0007169	Process	Transmembrane receptor protein tyrosine kinase signaling pathway	TAS	7556068
GO:0007275	Process	Multicellular organism development	IBA	21873635
GO:0007422	Process	Peripheral nervous system development	IEA
GO:0007507	Process	Heart development	IEA
GO:0007528	Process	Neuromuscular junction development	IEA
GO:0008022	Function	Protein C-terminus binding	IPI	15520177
GO:0008045	Process	Motor neuron axon guidance	IEA
GO:0008284	Process	Positive regulation of cell population proliferation	IBA	21873635
GO:0009925	Component	Basal plasma membrane	IBA	21873635
GO:0010008	Component	Endosome membrane	IDA	16314522
GO:0014065	Process	Phosphatidylinositol 3-kinase signaling	IDA	7556068
GO:0016021	Component	Integral component of membrane	NAS	15609325
GO:0016323	Component	Basolateral plasma membrane	IDA	12646923
GO:0016324	Component	Apical plasma membrane	IEA
GO:0018108	Process	Peptidyl-tyrosine phosphorylation	IDA	12000754
GO:0019838	Function	Growth factor binding	IDA	7514177
GO:0019903	Function	Protein phosphatase binding	IPI	15899872
GO:0030182	Process	Neuron differentiation	IBA	21873635
GO:0030307	Process	Positive regulation of cell growth	IMP	21555369
GO:0032886	Process	Regulation of microtubule-based process	IDA	20937854
GO:0033088	Process	Negative regulation of immature T cell proliferation in thymus	IEA
GO:0033674	Process	Positive regulation of kinase activity	IBA	21873635
GO:0035556	Process	Intracellular signal transduction	IDA	19372587
GO:0038128	Process	ERBB2 signaling pathway	TAS
GO:0038143	Component	ERBB3:ERBB2 complex	IDA	12000754
GO:0042060	Process	Wound healing	IDA	12646923
GO:0042552	Process	Myelination	IEA
GO:0042802	Function	Identical protein binding	IPI	12000754, 16843263, 17148612, 19650109, 21203579, 21255571, 21480528, 22733765, 23436906
GO:0043125	Function	ErbB-3 class receptor binding	IPI	12000754
GO:0043209	Component	Myelin sheath	IEA
GO:0043235	Component	Receptor complex	IBA	21873635
GO:0043235	Component	Receptor complex	IDA	7514177, 23382219
GO:0043235	Component	Receptor complex	TAS	7556068
GO:0043406	Process	Positive regulation of MAP kinase activity	IDA	10572067
GO:0043410	Process	Positive regulation of MAPK cascade	IBA	21873635
GO:0043547	Process	Positive regulation of GTPase activity	ISS
GO:0045727	Process	Positive regulation of translation	IMP	21555369
GO:0045765	Process	Regulation of angiogenesis	NAS	15609325
GO:0045785	Process	Positive regulation of cell adhesion	IDA	7556068
GO:0045943	Process	Positive regulation of transcription by RNA polymerase I	IMP	21555369
GO:0046777	Process	Protein autophosphorylation	IDA	7556068
GO:0046982	Function	Protein heterodimerization activity	IPI	7556068
GO:0048471	Component	Perinuclear region of cytoplasm	IEA
GO:0048709	Process	Oligodendrocyte differentiation	IEA
GO:0050679	Process	Positive regulation of epithelial cell proliferation	IDA	10572067
GO:0051897	Process	Positive regulation of protein kinase B signaling	TAS
GO:0070372	Process	Regulation of ERK1 and ERK2 cascade	IMP	16314522
GO:0071363	Process	Cellular response to growth factor stimulus	IDA	20010870
GO:0071364	Process	Cellular response to epidermal growth factor stimulus	IMP	27134172
GO:0090314	Process	Positive regulation of protein targeting to membrane	IDA	20010870
GO:1901185	Process	Negative regulation of ERBB signaling pathway	TAS
GO:2000145	Process	Regulation of cell motility	TAS

MIM	HGNC	e!Ensembl
164870	3430	ENSG00000141736

Protein

UniProt ID

P04626

Protein name

Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)

Protein function

Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone.

PDB

1MFG , 1MFL , 1MW4 , 1N8Z , 1QR1 , 1S78 , 2A91 , 2JWA , 2KS1 , 2L4K , 2N2A , 3BE1 , 3H3B , 3MZW , 3N85 , 3PP0 , 3RCD , 3WLW , 3WSQ , 4GFU , 4HRL , 4HRM , 4HRN , 4NND , 5K33 , 5KWG , 5MY6 , 5O4G , 5OB4 , 5TQS , 6ATT , 6BGT , 6J71 , 6LBX , 6OGE , 7JXH , 7MN5 , 7MN6 , 7MN8 , 7PCD , 7QVK , 8FFJ , 8HGO , 8HGP , 8JYQ , 8JYR , 8PWH , 8Q6J , 8U4K , 8U4L , 8U8X

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01030	Recep_L_domain	52 → 173	Receptor L domain	Repeat
PF00757	Furin-like	183 → 343	Furin-like cysteine rich region	Domain
PF01030	Recep_L_domain	366 → 486	Receptor L domain	Repeat
PF14843	GF_recep_IV	510 → 643	Growth factor receptor domain IV	Domain
PF07714	PK_Tyr_Ser-Thr	720 → 976	Protein tyrosine and serine/threonine kinase	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed in a variety of tumor tissues including primary breast tumors and tumors from small bowel, esophagus, kidney and mouth. {ECO:0000269|PubMed:15380516}.

Sequence

MELAALCRWGLLLALLPPGAASTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNL
ELTYLPTNASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGTQLFEDNYALAVLDNG
DPLNNTTPVTGASPGGLRELQLRSLTEILKGGVLIQRNPQLCYQDTILWKDIFHKNNQLA
LTLIDTNRSRACHPCSPMCKGSRCWGESSEDCQSLTRTVCAGGCARCKGPLPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACP
YNYLSTDVGSCTLVCPLHNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREVRAVTSAN
IQEFAGCKKIFGSLAFLPESFDGDPASNTAPLQPEQLQVFETLEEITGYLYISAWPDSLP
DLSVFQNLQVIRGRILHNGAYSLTLQGLGISWLGLRSLRELGSGLALIHHNTHLCFVHTV
PWDQLFRNPHQALLHTANRPEDECVGEGLACHQLCARGHCWGPGPTQCVNCSQFLRGQEC
VEECRVLQGLPREYVNARHCLPCHPECQPQNGSVTCFGPEADQCVACAHYKDPPFCVARC
PSGVKPDLSYMPIWKFPDEEGACQPCPINCTHSCVDLDDKGCPAEQRASPLTSIISAVVG
ILLVVVLGVVFGILIKRRQQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVRENRGRLGSQDLLNWCMQIAKGMSYLEDVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVSEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDA
EEYLVPQQGFFCPDPAPGAGGMVHHRHRSSSTRSGGGDLTLGLEPSEEEAPRSPLAPSEG
AGSDVFDGDLGMGAAKGLQSLPTHDPSPLQRYSEDPTVPLPSETDGYVAPLTCSPQPEYV
NQPDVRPQPPSPREGPLPAARPAGATLERPKTLSPGKNGVVKDVFAFGGAVENPEYLTPQ
GGAAPQPHPPPAFSPAFDNLYYWDQDPPERGAPPSTFKGTPTAENPEYLGLDVPV

Sequence length

1255

Interactions

View interactions

Show/Hide Unknown Diseases (8)

Disease term	Disease name	Evidence	Source
Unknown
Glioma	glioma susceptibility 1	Knockdown of lncGRS-1, a primate-conserved, nuclear-enriched lncRNA, inhibits the growth and proliferation of primary adult and pediatric glioma cells, but not the viability of normal brain cells.	GenCC, CBGDA
Visceral Neuropathy	visceral neuropathy, familial, 2, autosomal recessive		GenCC
Hirschsprung Disease	Hirschsprung disease		GenCC
Bipolar Disorder	Bipolar Disorder		GWAS
Asthma	Asthma		GWAS
Systemic lupus erythematosus	Systemic lupus erythematosus		GWAS
Inflammatory Bowel Disease	Inflammatory Bowel Disease		GWAS
Atrial Fibrillation	Atrial Fibrillation		GWAS

Show/Hide Text Mining Associations (526)

Disease Name	Relationship Type	References
Associations from Text Mining
5 alpha Fluorouracil toxicity	Associate	22351696
Aberrant Crypt Foci	Associate	29222172
Acquired ichthyosis	Associate	36303457
Adenocarcinoma	Associate	10686540, 12365012, 1398227, 15167937, 15668283, 15870067, 16189154, 16731604, 16863509, 1687493, 16963452, 17143264, 17575133, 19055823, 19292734 View all (102 more)
Adenocarcinoma	Stimulate	11406641, 14645692, 29725274, 29802704, 29866946, 36617420, 37340403, 8097369
Adenocarcinoma Bronchiolo Alveolar	Associate	15167937, 16189154, 20521350
Adenocarcinoma Mucinous	Associate	15960065, 20003286, 22317764, 23078675, 25120802, 25338994, 25986173
Adenocarcinoma Mucinous	Inhibit	19479974, 23768133, 32781417
Adenocarcinoma Mucinous	Stimulate	24705517, 32813918
Adenocarcinoma Of Esophagus	Associate	17143264, 7794072
Adenocarcinoma of Lung	Associate	16189154, 16825508, 17487277, 19875972, 20855837, 21966491, 22071781, 22140546, 22317764, 22325357, 22761469, 23328547, 24317180, 24835218, 25079552 View all (55 more)
Adenocarcinoma Papillary	Associate	19920829, 20417484, 20700124
Adenoma	Associate	10686540, 16686942, 23413122, 3390372
Adenoma	Stimulate	26048755
Adenoma Pleomorphic	Associate	19061288, 28681314, 30390196, 39384827
Adenomyoma	Associate	40116917
Agnosia	Associate	31723167, 40133809
Agnosia	Stimulate	40148195
Allan Herndon Dudley syndrome	Stimulate	16168103
Alternating hemiplegia of childhood	Associate	19734843
Anaplasia	Associate	15328518
Androgen Insensitivity Syndrome	Associate	28859123, 35641658
Anemia	Associate	37358854
Anemia Aplastic	Associate	25119012
Aneuploidy	Associate	20689761, 22169037, 24344012, 25337277, 7545416, 7553681
Angina Stable	Associate	28859471, 33203645
Anodontia	Associate	28178681, 36351537
Anxiety	Associate	32284770
Aphasia Broca	Associate	18256926
Arrest of spermatogenesis	Associate	21550039
Arthritis Rheumatoid	Associate	11229455, 15743888, 28148290, 35140805
Arthropathy progressive pseudorheumatoid of childhood	Associate	39780157
Ascites	Associate	36933411
Asthma	Associate	30639343, 32512817, 35473352, 37336194
Astrocytoma	Associate	15328518, 20331873, 21804458
Astrocytoma	Inhibit	39794852
Ataxia Telangiectasia	Inhibit	33203854
Auditory Perceptual Disorders	Stimulate	37437231
Barrett Esophagus	Associate	10666385, 11007435, 11406641, 1398227, 14645692, 19292734, 20557373, 22252257, 23180947, 25085335, 30208867, 7907608
Biliary Atresia	Associate	16739351
Biliary Tract Neoplasms	Associate	19777609, 21087480, 26022204, 32353192, 32447492, 35583261, 36089135, 36257294, 37139666, 39793339, 39803868
Bipolar Disorder	Associate	29197740
Blood Coagulation Disorders	Associate	33182810
Bone Diseases	Associate	33307492, 33748269
Bone Marrow Diseases	Associate	17262082, 22014070, 32458584
Brain Diseases	Associate	22898337, 28210910, 29260362, 40640833
Brain Neoplasms	Associate	10861689, 17541441, 17695462, 19937674, 21914172, 21929800, 22233926, 23180004, 23224376, 25292034, 26028092, 26313663, 26410082, 27926948, 28008153 View all (8 more)
Brain Neoplasms	Stimulate	12001113, 30373904, 35905534
Breast Carcinoma In Situ	Associate	19701073, 21264346, 31907376, 31932682
Breast Diseases	Associate	1672254, 2849975
Breast Neoplasms	Associate	10213923, 10233167, 10318905, 10399623, 10408862, 10441522, 10474685, 10480346, 10497265, 10550311, 10569141, 10604729, 10604737, 10638965, 10681513 View all (3154 more)
Breast Neoplasms	Stimulate	10692468, 12888823, 16683887, 16849266, 18710881, 19347621, 21372379, 22901142, 22989461, 23112837, 23341341, 24556625, 24887547, 25803816, 25906114 View all (13 more)
Breast Neoplasms	Inhibit	17885672, 17910759, 26670335, 26679376, 27400969, 27935425, 33027559, 33975551, 38578394, 40597882
Breast Neoplasms Male	Associate	11449307, 23146383, 24080492, 24322022, 25906114, 25948676, 26313461, 33964913, 40302091
Bronchiolitis Viral	Associate	30562046
Calcinosis	Associate	18256879
Calcinosis	Stimulate	28900139, 33927073
Calcinosis Cutis	Associate	12001113, 12209684, 12569382, 14735191, 15324690, 15865067, 16739334, 16998594, 17013794, 17361205, 17963511, 18184439, 18822183, 20023245, 22092393 View all (37 more)
Carcinogenesis	Associate	10036781, 10567533, 15493579, 15550452, 15861214, 16158937, 16445653, 16686942, 17245339, 19055823, 19331129, 20187983, 20522955, 20712882, 22586447 View all (19 more)
Carcinogenesis	Stimulate	12101225, 12947087, 14676809, 16648555, 23279575, 23730206, 31438969
Carcinoma	Associate	13680193, 15305194, 20574155, 27929428, 7667291
Carcinoma Acinar Cell	Associate	37094236
Carcinoma Adenoid Cystic	Associate	17142577, 19309723, 21204718, 27491809
Carcinoma Basal Cell	Associate	18752048, 21672245, 2470827, 25099655, 25197398, 28388586, 30173251, 33161227, 35476550
Carcinoma Ductal	Associate	10861689, 11994759, 1346789, 14567723, 16033090, 16619488, 1672872, 16751301, 16869955, 1701961, 17309600, 19318498, 19596972, 1973597, 20667129 View all (30 more)
Carcinoma Ductal	Stimulate	20071783, 22471961, 28075663, 2849975, 33927073, 35051228
Carcinoma Ductal	Inhibit	40681988
Carcinoma Ductal Breast	Associate	10656732, 11272892, 11882907, 12068329, 15696127, 17189983, 19448591, 20069504, 20126619, 21943250, 22119825, 23421821, 24086515, 25186428, 26062614 View all (8 more)
Carcinoma Ductal Breast	Stimulate	1701961, 27644608, 37246414
Carcinoma Embryonal	Stimulate	20209452
Carcinoma Endometrioid	Associate	11553860, 1325950, 14752523, 17128692
Carcinoma Hepatocellular	Associate	11900227, 16038042, 17150109, 26595522, 27029710, 28713927, 29487225, 31363003, 32515546, 33168027, 36587184, 37914817
Carcinoma Hepatocellular	Stimulate	19610068, 24719890
Carcinoma in Situ	Stimulate	16965395, 22468084
Carcinoma in Situ	Associate	1973597, 19915523, 22392042, 24551292, 29654370, 31734230, 36812689
Carcinoma Intraductal Noninfiltrating	Associate	10604741, 10656732, 10861689, 11304576, 1346789, 15696127, 16033090, 16528377, 17060931, 17069663, 17453296, 18043578, 18681955, 19383888, 19732720 View all (49 more)
Carcinoma Intraductal Noninfiltrating	Stimulate	19915523, 2849975
Carcinoma Intraductal Noninfiltrating	Inhibit	28075663, 30657766
Carcinoma Lobular	Stimulate	1346789, 21326816, 22901443
Carcinoma Lobular	Inhibit	17239264, 20423478, 40681988
Carcinoma Lobular	Associate	17722109, 20550696, 21126378, 22864775, 22961065, 22990544, 25385074, 25804795, 27811364, 27837612, 31229512, 32782013, 33441174, 33923191, 34257600 View all (4 more)
Carcinoma Medullary	Stimulate	1346789
Carcinoma Medullary	Associate	14567723, 7992839
Carcinoma Merkel Cell	Associate	18408656, 28359267
Carcinoma Mucoepidermoid	Associate	23361279, 26575266, 28327999, 37422821
Carcinoma Neuroendocrine	Associate	21633298
Carcinoma Non Small Cell Lung	Associate	10424999, 10761709, 10838527, 10945494, 11986780, 12173335, 12359054, 15751020, 16080566, 16208701, 16598760, 16825508, 16847810, 17094398, 17094416 View all (112 more)
Carcinoma Non Small Cell Lung	Inhibit	18687633
Carcinoma Ovarian Epithelial	Associate	10320143, 12950146, 15571614, 17465257, 18182111, 18567994, 18628764, 19272639, 23791828, 25501060, 25520097, 26566289, 26937910, 33834328, 34839022, 8096121 View all (1 more)
Carcinoma Pancreatic Ductal	Associate	18505086, 20430737, 27187683, 27321183, 29725336, 35684936, 38167622
Carcinoma Papillary	Associate	1352125, 16116605, 17009989, 17451461, 18248390, 20673976, 22329832, 23529321, 3390372
Carcinoma Papillary	Stimulate	15208622, 8617452
Carcinoma Renal Cell	Associate	11849151, 15816631, 20462447, 21461646, 24966967, 28315738, 28718916, 33285627, 33731191, 33901032, 35171661, 36360294, 36857998, 37917812, 39353993
Carcinoma Renal Cell	Stimulate	1686289, 27770810, 28187748
Carcinoma Renal Cell	Inhibit	22554477
Carcinoma Signet Ring Cell	Associate	18224443, 35618879
Carcinoma Small Cell	Associate	30717682, 33901032, 36617420, 36812376
Carcinoma Squamous Cell	Associate	11275796, 15692721, 15865067, 16033092, 16080566, 16264381, 17465227, 20237991, 20881644, 22009799, 24390348, 2470827, 26479420, 27145277, 28423512 View all (10 more)
Carcinoma Squamous Cell	Stimulate	22736332, 36617420, 37340403
Carcinoma Transitional Cell	Associate	14520464, 15816631, 1673627, 1712624, 17987577, 27539085
Carcinoma Transitional Cell	Stimulate	30296252
Carcinosarcoma	Associate	14611676, 16445668, 22498937, 31477811, 32114514, 34972830, 36178283, 37530323, 38262242
Cardiotoxicity	Associate	19800453, 25885598, 28781309, 35110416
Cardiovascular Diseases	Associate	24243566, 32398106
Cardiovascular Diseases	Stimulate	37246414
Celiac Disease	Inhibit	22136669
Cell Transformation Neoplastic	Associate	19661293
Central Nervous System Diseases	Associate	27198655
Cerebral Hemorrhage	Stimulate	36316658
Cerebrospinal Fluid Rhinorrhea	Associate	34920954
Cerebrovascular Disorders	Associate	35609807
Chemical and Drug Induced Liver Injury	Associate	32591879, 37358854
Cholangiocarcinoma	Associate	16311342, 17322545, 18087285, 20731018, 21492330, 23052372, 25536104, 26022204, 29848569, 30971436, 31805897, 32173382, 35897137, 37119523, 37437231, 37814942, 39198311, 39375615 View all (3 more)
Cholangiocarcinoma	Stimulate	25712293
Cholangitis Sclerosing	Associate	35897137, 36252869
Cholecystitis	Associate	36546234
Cholestasis	Associate	32591879
Chondrosarcoma	Associate	26966351
Choriocarcinoma	Stimulate	15330164
Choroidal Effusions	Associate	20217132
Chromosomal Instability	Associate	22830453, 31784614, 32738630, 33299647, 34504292, 37039257
Chromosomal Instability	Stimulate	35722719
Chromosome 17 deletion	Associate	20689761, 20803611, 25337277
Chromosome Aberrations	Associate	25481507, 27417320
Chromosome Disorders	Associate	24098497
Chronic Kidney Disease Mineral and Bone Disorder	Associate	29511113
Classical Lissencephalies and Subcortical Band Heterotopias	Associate	27808478
Clear cell metastatic renal cell carcinoma	Associate	29517810, 39366934
Cleft Lip	Associate	18978678
Cleft Palate	Associate	31262291
Cold Injury	Associate	22460807
Colonic Diseases	Associate	37793085
Colonic Neoplasms	Associate	10686540, 12100028, 1357006, 15493579, 15632176, 15888451, 17164780, 18326857, 24659651, 24733427, 25142811, 26625779, 27821098, 30373904, 33844372
Colonic Neoplasms	Stimulate	11870539, 7915904
Colorectal Neoplasms	Associate	11139320, 11857296, 12196377, 12571082, 15143334, 15757908, 15888451, 16302076, 16681853, 16830272, 16882699, 18931700, 19118499, 19691111, 20970032 View all (111 more)
Colorectal Neoplasms	Stimulate	32856866
Congenital Abnormalities	Associate	18978678
Congenital disorder of glycosylation type 1B	Associate	26062614
Corneal dystrophy Avellino type	Stimulate	1686289
COVID 19	Associate	35855804
Craniopharyngioma	Associate	23344868
Crazy paving pattern	Associate	36029220
Cushing's symphalangism	Stimulate	36006442
Cystic Disease Of Lung	Associate	1686289, 25070172
Cysts	Associate	18587325
Death	Associate	10096969, 10838527, 11205461, 11920494, 1672253, 18236071, 18425397, 18645672, 18767043, 19640195, 20178580, 20338615, 22126548, 22987085, 24403186 View all (5 more)
Death	Stimulate	15274401, 25031741
Diabetes Mellitus	Inhibit	35609807
Diabetes Mellitus	Associate	35609807, 36837510
Diabetes Mellitus Type 1	Associate	36303457
Diabetes Mellitus Type 2	Associate	26148588, 27396353
Diarrhea	Associate	20479410, 29254887, 34843401, 35101045
Diarrhea 5 With Tufting Enteropathy Congenital	Associate	18364263
Disease	Associate	11920466, 15900577, 36730339, 37870536
Disease Progression	Associate	29561699
Down Syndrome	Associate	10757805
Drug Hypersensitivity	Associate	17490486
Drug Related Side Effects and Adverse Reactions	Associate	11959134, 12419746, 15235125, 17014727, 19467571, 26556305, 26801900, 28031413, 29416334, 29725336, 30870514, 33947960, 34290709, 37728467, 38097342
Drug Related Side Effects and Adverse Reactions	Stimulate	34361688
Duane Retraction Syndrome	Associate	30941651
Dyggve Melchior Clausen syndrome	Associate	40352186
Dysplastic Nevus Syndrome	Associate	23348899
Embolism	Associate	25885256
Encephalitis Herpes Simplex	Associate	36038884
Endocrine Gland Neoplasms	Associate	30205045, 39256703
Endocrine System Diseases	Associate	15452162, 16168139, 21935603, 22854050, 22964581, 29563635, 32684154, 33086721
Endocrine System Diseases	Stimulate	37460683
Endometrial Hyperplasia	Associate	16189154, 37565251
Endometrial Neoplasms	Associate	14663583, 14752523, 1687493, 17695457, 18204294, 18334972, 19088718, 19509570, 19756737, 19840887, 20167054, 20593959, 20664599, 21305022, 21734474 View all (29 more)
Endometriosis	Associate	27323121, 30428062
Enteritis	Associate	35901658
Ependymoma	Associate	20713864, 23836190, 25859842, 33085768, 37870091
Epidermodysplasia Verruciformis	Associate	37084607
Epstein Barr Virus Infections	Associate	17376931
Epstein Barr Virus Infections	Inhibit	25402957
Erosive Adenomatosis of the Nipple	Associate	22006374
Esophageal Neoplasms	Associate	17143264, 20628381, 21481261, 22767218, 27198655, 27741011, 29865880, 32022229, 32728182, 33151397, 34764264, 37437231
Esophageal Squamous Cell Carcinoma	Associate	15785739, 17622245, 19128465, 20628381, 23207070, 23426935, 24052437, 26099724, 26857264, 30373904, 32209107, 35524932
Esophageal Squamous Cell Carcinoma	Stimulate	29866946
Exanthema	Associate	30295016, 34843401, 37358854
Eyelid Neoplasms	Associate	11068992
Familial cylindromatosis	Associate	26336083, 29884612
Fanconi Anemia	Associate	35484593
Farber Lipogranulomatosis	Associate	30373904
Fatty Liver	Associate	32591879
Fatty Liver Alcoholic	Stimulate	32591879
Fever	Associate	21992561
Fibroadenoma	Associate	15646810
Fibrocystic Breast Disease	Associate	27713419, 7560201
Fibrosarcoma	Associate	26269601
Fibrosis	Associate	35980387
Flatfoot	Associate	36812689
Floating harbor syndrome	Associate	29526969
Focal Nodular Hyperplasia	Stimulate	28947799
Fragile X Syndrome	Associate	11432618
Fused Teeth	Associate	29975246
Gallbladder Neoplasms	Associate	16686942, 17595796, 22468084, 24009453, 25416598, 26022204, 26320430, 27644637, 31106632, 31752867, 32024900, 33563892, 34798839, 36546234, 37787296, 38092180, 38554345, 39803868 View all (3 more)
Gallstones	Stimulate	38554345
Gastrinoma	Associate	7911296
Gastro enteropancreatic neuroendocrine tumor	Associate	22558472
Gastroesophageal Reflux	Associate	21323962, 22567741, 23874879, 24114855, 25292034, 26313663, 30745584, 34102137, 37055161
Gastroesophageal Reflux	Stimulate	24576036
Gastrointestinal Diseases	Associate	36370604
Gastrointestinal Neoplasms	Associate	20116405, 24201755, 30373904, 32372174, 33161227
Gastrointestinal Stromal Tumors	Associate	30221743
Genetic Diseases Inborn	Associate	3034598, 7909221
Genital Diseases Female	Associate	12833457
Genital Neoplasms Female	Associate	27770810
Glassy cell carcinoma of the cervix	Associate	28859123
Glioblastoma	Associate	15328518, 18772890, 19288188, 23433400, 27409668, 31320597, 34530675, 37277696, 39394177
Glioblastoma	Stimulate	22794670, 26906551, 33892666
Glioma	Associate	11729374, 15812817, 16097449, 17255279, 20446891, 21804458, 24144028, 26906551, 28161812, 36805678
Glioma	Stimulate	15948146
Glioma	Inhibit	27852048, 33892666
Granulosa Cell Tumor	Associate	24687970
Granulosa cell tumor of the ovary	Associate	24687970
Growth Factors Combined Defect of	Associate	28164408
Growth Hormone Secreting Pituitary Adenoma	Associate	16622555
Hamartoma Syndrome Multiple	Associate	20712882
Harlequin syndrome	Associate	22903686
Head and Neck Neoplasms	Associate	12915878, 20237991, 21986939, 24858640, 33161227, 7519839
Head and Neck Neoplasms	Stimulate	39369912
Heart Diseases	Associate	23975515, 28781309
Heart Failure	Associate	23975515
Hemangiosarcoma	Associate	17214349
Hemorrhagic Fever American	Associate	30520947
Hepatitis B	Associate	18204202, 22169037, 22252842, 22524806, 22830453, 23046482, 23930211, 23936456, 24177593, 25804795, 26173622, 26837394, 26871511, 27756653, 28260828 View all (5 more)
Hepatitis B	Stimulate	19610068, 22961208, 24274821, 27029768, 35778884
Hepatoblastoma	Associate	35311451
Hereditary Angioedema Type III	Associate	22510516
Hereditary Breast and Ovarian Cancer Syndrome	Associate	10220407, 10497265, 11371225, 11821047, 12538688, 14625284, 15235125, 16152586, 18454859, 18505086, 18767043, 20177704, 20217132, 21323863, 21574647 View all (28 more)
Hereditary Breast and Ovarian Cancer Syndrome	Stimulate	10692468
Hereditary pancreatitis	Associate	26287187, 35203384
Hidrocystoma	Associate	14631375
Hyperostosis corticalis deformans juvenilis	Associate	15272283, 1701961, 22901142, 31650976, 32998859, 34624832
Hyperostosis corticalis deformans juvenilis	Stimulate	23620755
Hyperplasia	Associate	22364303
Hyperprolactinemia	Associate	20023245
Hypersensitivity Delayed	Associate	19805669
Hypersensitivity Immediate	Associate	38279318
Hypertension	Associate	24887458
Hypertrophy	Inhibit	24827991
Hypoglycemia	Associate	25854171
Hypomagnesemia primary	Associate	33161227
Hypoxia	Associate	14676809, 21672245, 23696831, 25596742, 27771839, 29603584
Hypoxia	Stimulate	23301758, 30670058, 32945388
Hypoxia Brain	Associate	30670058, 34290709, 35550513
Idiopathic Pulmonary Fibrosis	Associate	35980387
Immunodeficiency without anhidrotic ectodermal dysplasia	Associate	37316414
Immunologic Deficiency Syndromes	Associate	10233167
Impotence Vasculogenic	Associate	23279650
Infections	Stimulate	19610068
Infertility	Associate	36303457
Inflammation	Associate	20932292, 25809292, 26112049, 30082828, 32980776, 35473352, 36899812, 9301551
Inflammation	Stimulate	26114632
Inflammation	Inhibit	26484354, 40613209
Inflammatory Breast Neoplasms	Associate	15039594, 16261404, 16755113, 17351259, 17700572, 17848951, 18230143, 19902352, 20406946, 20626396, 20932292, 21153052, 21559822, 22813402, 23396049 View all (21 more)
Inflammatory Breast Neoplasms	Stimulate	18836277
Insulin Resistance	Associate	11779863, 26945364
Intervertebral Disc Degeneration	Associate	29476072, 37340393
Intestinal Diseases	Associate	20082479, 23874879, 26039836, 35911441
Intestinal Neoplasms	Stimulate	10393360, 11820720
Intestinal Neoplasms	Associate	16718853, 23348899, 23656792, 26625793, 29046940, 32058557
Intraoperative Complications	Associate	39985907
Kidney Diseases Cystic	Associate	1686289
Kidney Failure Chronic	Stimulate	1686289
Kidney Failure Chronic	Associate	20581805, 31030487, 40036771
Kidney Neoplasms	Associate	15699574, 37917812, 38052324
Lactation Disorders	Associate	22797202
Laron Syndrome	Associate	36459284
Laryngeal Neoplasms	Associate	27813589
Laryngitis	Associate	27077364
Leiomyosarcoma	Associate	26287187
Leprosy	Associate	24676663
Leprosy Lepromatous	Associate	24676663
Leprosy Tuberculoid	Associate	24676663
Lesch Nyhan Syndrome	Inhibit	33203854
Lesch Nyhan Syndrome	Associate	35876391
Leukemia	Associate	25395422
Leukemia Biphenotypic Acute	Associate	27623034
Leukemia Lymphocytic Chronic B Cell	Associate	19383911, 26506417, 38280423
Leukemia Promyelocytic Acute	Associate	2430175, 2491776
Leukocyte adhesion deficiency type 1	Associate	37253111, 38097342
Leukopenia	Associate	39969377
Leukoplakia	Associate	23492901
Leukoplakia Oral	Associate	23492901
Li Fraumeni Syndrome	Associate	24835218, 32246378
Liver Cirrhosis Biliary	Associate	25681308
Liver Diseases	Associate	32591879
Liver Failure	Associate	16038042, 28860898
Lown Ganong Levine Syndrome	Associate	39762854
Lung Diseases	Associate	17361205, 26102513, 26285240, 29526969, 29929548, 34487971, 35017776, 38588887, 40665654
Lung Neoplasms	Associate	10534697, 11986780, 1306309, 13680193, 1483946, 15258328, 16158937, 16847810, 17627612, 19055823, 19452548, 19472407, 21847121, 21914172, 22899293 View all (64 more)
Lymphangitis	Associate	34516491
Lymphatic Diseases	Associate	19362044, 35307014
Lymphatic Metastasis	Stimulate	10213923, 10469313, 11692145, 1352125, 15643600, 21914949, 24762542, 26099724, 26985869, 27756653, 28075663, 29489698, 30383658, 32210254, 38374017, 39395300, 40482189 View all (2 more)
Lymphatic Metastasis	Associate	12359054, 12649339, 1350789, 14675323, 14752523, 17322545, 18992636, 19256737, 20430735, 21487407, 21966491, 22407396, 22799305, 22907801, 23026198 View all (45 more)
Lymphatic Metastasis	Inhibit	29873317
Lymphoma Follicular	Associate	12910513, 32436191
Lymphoma Large B Cell Diffuse	Inhibit	29936139
Lymphoma Non Hodgkin	Associate	11406641, 17385213, 27559738, 32445084
Macular Degeneration	Associate	30870514
Macular Edema	Inhibit	16311351
Mallory Weiss Syndrome	Associate	22646266, 36418168
Mammary Neoplasms Animal	Associate	20424164, 20581867, 2153396, 22119832, 28632792, 2901952, 3034598
Medulloblastoma	Associate	12709419, 19017278, 23836190, 7880726
Melanoma	Associate	25684465, 25769001, 26269601, 26967479, 29941010, 30093446, 35915735, 36303457
Melanoma Cutaneous Malignant	Associate	26206558
Meningeal Carcinomatosis	Associate	26313663
Meningeal Neoplasms	Associate	37548547
Meningioma	Associate	18808065, 19431122, 22797202, 30335819, 37870091
Mesothelioma	Associate	12683876
Mesothelioma Malignant	Associate	12683876, 31752449
Metabolic Diseases	Associate	35240786
Microsatellite Instability	Associate	29089060, 32627883, 33726687, 33844372, 36902296, 37814942
Migraine Disorders	Associate	34113003
Mouth Diseases	Associate	21453513, 38548353
Mouth Neoplasms	Associate	12915878, 24399009, 25792810
Mucopolysaccharidosis III	Associate	18086299, 19074216
Mucositis	Associate	37358854
Mullerian aplasia	Associate	27770810
Multiple Myeloma	Associate	25894462, 37373090
Multiple Pulmonary Nodules	Associate	36029220
Muscle Neoplasms	Stimulate	1712624
Muscular dystrophy congenital with central nervous system involvement	Associate	12853349
Myotonic Dystrophy	Associate	30130447
Nausea	Associate	19596945
Necrosis	Stimulate	12627502
Necrosis	Associate	31757056, 37068349
Nemaline myopathy 5	Associate	17189983
Neonatal herpes	Associate	34948316
Neoplasm Invasiveness	Associate	16533770, 1672254, 19383888, 19535820, 20473902, 21453513, 21860549, 22392042, 22524806, 23052372, 23751022, 25720673, 27644608, 28886093, 29493262 View all (9 more)
Neoplasm Invasiveness	Stimulate	22901141, 27559738
Neoplasm Metastasis	Associate	10190316, 11422380, 11682064, 11692145, 11821047, 12001113, 1358163, 14567724, 14631375, 14710234, 15112275, 15480434, 15542424, 15550452, 15771595 View all (189 more)
Neoplasm Metastasis	Stimulate	10469313, 11920494, 14579298, 15692222, 16168103, 19419954, 20071783, 21865043, 22447278, 23464451, 25031741, 25559688, 26553611, 26632727, 27119647 View all (5 more)
Neoplasm Metastasis	Inhibit	33112563
Neoplasm Micrometastasis	Associate	23766685
Neoplasm Recurrence Local	Associate	22147002, 22621334
Neoplasms	Associate	10096969, 10190316, 10220407, 10320143, 10469313, 10474684, 10474685, 10501854, 10534697, 10550311, 10757805, 10761709, 10854209, 11092612, 11139320 View all (1491 more)
Neoplasms	Stimulate	10569141, 10945494, 11398888, 11682064, 11796827, 11826915, 12833457, 12973835, 1346748, 1355662, 16085689, 16417653, 1672597, 1673627, 18224443 View all (53 more)
Neoplasms	Inhibit	10615931, 16686942, 16980602, 18650488, 19372580, 22418568, 23244222, 23625594, 25928431, 27174587, 27935425, 31009269, 35179782, 35307014, 37945655, 39353993 View all (1 more)
Neoplasms Basal Cell	Associate	7819052
Neoplasms Cystic Mucinous and Serous	Associate	11328410, 11371228, 16721043, 1686289, 19010816, 19461510, 21915118, 22531721, 23078675, 25669172, 26506417, 27770810, 32601075, 32709539, 33077919 View all (4 more)
Neoplasms Cystic Mucinous and Serous	Stimulate	17945336, 18567994
Neoplasms Ductal Lobular and Medullary	Associate	19167937, 25009010
Neoplasms Germ Cell and Embryonal	Associate	12194993, 27569093
Neoplasms Germ Cell and Embryonal	Stimulate	20209452
Neoplasms Glandular and Epithelial	Associate	11139320, 12966425
Neoplasms Squamous Cell	Associate	37862796, 40244261
Neoplasms Unknown Primary	Associate	21598042
Neoplastic Syndromes Hereditary	Associate	18405391, 29146616
Nerve Sheath Neoplasms	Associate	32017710
Neuralgia	Associate	26943575
Neurilemmoma	Associate	23354516, 24558021, 32017710
Neuroblastoma	Associate	14696059, 37664946
Neuroectodermal Tumors Primitive	Associate	16097449
Neuroendocrine Tumors	Associate	33144445, 36899368
Neurofibroma	Associate	32017710
Neurofibromatoses	Associate	34841831
Neurofibrosarcoma	Associate	18650488, 18927496, 37837931
Neurologic Manifestations	Associate	29751779
Neuroma Acoustic	Associate	18670322, 21659924, 23776562
Neutropenia	Associate	16332965, 37358854, 39969377
Non alcoholic Fatty Liver Disease	Associate	36587184
Non Muscle Invasive Bladder Neoplasms	Associate	14520464, 19889613, 26240484, 28205537, 28339163, 33050010, 33650041, 35655252, 35900488, 36737799, 37884420, 40086591, 8104920
Nonseminomatous germ cell tumor	Associate	20209452
Obesity	Associate	34174935, 36411648, 36837510
Oncogene Addiction	Associate	8464905
Onycholysis	Associate	14710203
Opitz GBBB Syndrome X Linked	Associate	39394177
Organizing Pneumonia	Associate	28755093
Oropharyngeal Neoplasms	Associate	34743703
Osteoarthritis	Associate	31886203
Osteogenesis imperfecta type 3	Associate	39384801
Osteoporosis	Associate	40660573
Osteosarcoma	Associate	11920494, 12569382, 14631380, 16007579, 16683887, 17998668, 21751203, 25674245, 26242268, 26464710, 26625779, 30610808
Ovarian Diseases	Associate	14676809, 23474221, 28849826
Ovarian Neoplasms	Associate	10497265, 10555747, 11092612, 11158614, 11237673, 11821047, 12461170, 12833457, 12942124, 12950146, 12966425, 1347042, 13680193, 14625284, 14679128 View all (78 more)
Pachyonychia Congenita	Associate	36116508
Paget Disease Extramammary	Associate	10469313, 11005214, 15920545, 1701961, 21914949, 25085898, 26722523, 31023612, 31899853, 32998859, 39358617
Paget Disease Extramammary	Stimulate	9328150
Paget's Disease Mammary	Associate	15920545, 1701961, 31899853, 32114594, 35364707
Pancreatic Diseases	Associate	8617452
Pancreatic Intraductal Neoplasms	Stimulate	23052372
Pancreatic Intraductal Neoplasms	Associate	36056133
Pancreatic Neoplasms	Associate	10615931, 11371228, 14647146, 15461591, 16082196, 16489645, 18381409, 19432892, 21110957, 21447618, 22134789, 22374460, 25416598, 26287187, 27237318 View all (17 more)
Pancreatic Neoplasms	Stimulate	9665487
Pancreatitis Chronic	Associate	7519839
Pancytopenia	Associate	32458584
Papilloma	Stimulate	29851704
Papilloma Inverted	Associate	7576290
Papillomavirus Infections	Stimulate	26138066
Paragangliomas 3	Associate	18310300
Paraneoplastic Cerebellar Degeneration	Stimulate	22351748
Paraneoplastic Syndromes	Associate	16764747
Paraneoplastic Syndromes Nervous System	Associate	22351748
Parkinson Disease	Associate	33552685
Peripheral Nervous System Diseases	Associate	30939096
Peritoneal Diseases	Associate	24668709
Peritonitis	Associate	37348349, 40665654
Personality Disorders	Associate	12950146, 20331873, 26114632, 26739972, 30103233, 31065110, 33950817, 35248133
Personality Disorders	Stimulate	19133120
Peutz Jeghers Syndrome	Associate	33244976
Pheochromocytoma	Associate	18310300
Phyllodes Tumor of the Prostate	Associate	17192792
Pituitary Neoplasms	Associate	16622555, 23413122
Platyspondylic Lethal Skeletal Dysplasia Torrance Type	Inhibit	33203854
Pleural Diseases	Associate	28146588, 36161776
Pleural Effusion	Associate	31534501
Polycystic Kidney Autosomal Dominant	Associate	16797938
Polycystic Kidney Autosomal Dominant	Stimulate	1686289
Polycystic Kidney Diseases	Associate	16797938
Polycystic liver disease	Associate	18587325
Polycystic Ovary Syndrome	Associate	26416764
Poroma	Associate	18516291, 20208479, 21310761, 21423156, 22577344, 23056620
Post Infectious Disorders	Associate	26810418
Postoperative Hemorrhage	Associate	37548547
Precancerous Conditions	Associate	32856866
Precursor Cell Lymphoblastic Leukemia Lymphoma	Stimulate	23936456
Precursor Cell Lymphoblastic Leukemia Lymphoma	Associate	26887048
Primary Ovarian Insufficiency	Stimulate	12942124
Prodromal Symptoms	Associate	16332965, 16718853, 18501066, 27027339, 33539970, 36631725, 36652446
Progesterone Resistance	Associate	30691046
Prolactinoma	Associate	24287797
Prostate cancer familial	Associate	18829572
Prostatic Hyperplasia	Associate	29234244
Prostatic Intraepithelial Neoplasia	Associate	37094236
Prostatic Neoplasms	Associate	10318905, 11786427, 11865006, 13680193, 14735191, 15720812, 17211467, 17701930, 17704139, 18337451, 18350153, 18645672, 18767028, 18767043, 19294521 View all (26 more)
Prostatic Neoplasms Castration Resistant	Associate	12173324, 14735192, 15139054, 17384772, 17998285, 21559022, 38427749
Prostatitis	Associate	11005213, 11920466, 12173324, 12365012, 13680193, 14735191, 15139054, 15448811, 16152586, 18350153, 19294521, 27052161, 8650201
Protein S Deficiency	Associate	32017710
Pulmonary Disease Chronic Obstructive	Associate	33469280
Radiation Injuries	Associate	36530656
Recombinant chromosome 8 syndrome	Associate	30327465, 33098995, 36401316
Rectal Neoplasms	Associate	19368728, 24146218, 26134512, 26632727, 34319852
Recurrence	Associate	21050306, 26632727
Renal cell carcinoma 1	Associate	36038884
Respiratory Tract Infections	Associate	28755093, 38052324
Retinal Diseases	Associate	32945388
Retinal Dysplasia	Associate	11007435, 19292734, 20557373, 24853183, 27559738, 35897137
Rhabdomyosarcoma	Stimulate	34418214
Rhabdomyosarcoma Embryonal	Associate	16729016, 34418214
Rufous oculocutaneous albinism	Stimulate	18583876
Rufous oculocutaneous albinism	Associate	37097008
Salivary Duct Calculi	Associate	14645349, 15900577, 20371674, 23429737, 23583282, 25343854, 27103403, 28681314, 29492965, 30289966, 30390196, 30946933, 31609094, 32310325, 32350809 View all (4 more)
Salivary Duct Calculi	Stimulate	23933559, 37422821
Salivary Gland Adenoma Pleomorphic	Associate	30946933
Salivary Gland Diseases	Associate	37793085
Salivary Gland Neoplasms	Associate	19309723, 22240798, 26247885, 28681314, 32067683, 32310325, 37246414, 37422821, 9443087
Sarcoma	Associate	15015617
Sarcoma Ewing	Associate	17695539
Sarcoma Synovial	Associate	12414507, 15641030, 16195766, 18448562
Sarcopenia	Associate	40660573
Schizophrenia	Associate	18159252
Schwannomatosis	Associate	32017710
Sebaceous Gland Neoplasms	Stimulate	11068992
Seizures	Associate	27061526
Serositis	Associate	26034355
Sexual Dysfunction Physiological	Associate	31196001
Short Bowel Syndrome	Associate	24576036
Sick Sinus Syndrome	Associate	12368191, 16048908, 1672255, 24226713, 27748277, 27812689, 37103916, 40347583, 7798300, 7908410
Sleep Disorders Circadian Rhythm	Associate	29848569, 38622987
Small Cell Lung Carcinoma	Associate	31699089, 35478134
Smith McCort Dysplasia	Associate	29713003
Solitary Fibrous Tumors	Associate	20527023
Space Motion Sickness	Inhibit	31082509
Spinocerebellar Degenerations	Stimulate	16764747
Spinocerebellar Degenerations	Associate	26336987, 32772458
Squamous Cell Carcinoma of Head and Neck	Associate	14748745, 15592685, 15692721, 16547470, 18364263, 19362044, 19430297, 20429940, 20596843, 21986939, 22990553, 23371912, 23468880, 23563900, 24278325 View all (16 more)
Squamous Intraepithelial Lesions	Associate	27559738, 32445084
Status Asthmaticus	Inhibit	30639343
Stomach Diseases	Associate	11680933, 15668283, 24914350, 25631875, 32889387, 33755862, 35911441
Stomach Neoplasms	Associate	10393360, 10679740, 10754464, 11680933, 11820720, 12579211, 1350789, 1379062, 15646832, 15668283, 16718853, 17431415, 18224443, 19061514, 19156142 View all (335 more)
Stomach Neoplasms	Inhibit	26078567, 26970343
Stomach Neoplasms	Stimulate	30351859, 31737131
Stomatitis	Associate	34843401
Substance Related Disorders	Associate	31365168
Sveinsson Chorioretinal Atrophy	Associate	34493366
Synovial Cyst	Associate	11229455
Tachycardia Atrioventricular Nodal Reentry	Associate	18629779, 22524806, 28079792
Tachycardia Atrioventricular Nodal Reentry	Stimulate	25292034, 33923191
Takotsubo Cardiomyopathy	Associate	32591879
Tarlov Cysts	Stimulate	36814374, 38415549
Teratocarcinoma	Stimulate	20209452
Teratoma	Associate	12124830
Tertiary Lymphoid Structures	Stimulate	11826915, 24375039, 26339420, 29409530, 33285627, 38151289
Tertiary Lymphoid Structures	Associate	14745865, 15643600, 18187484, 19271345, 19362044, 19657672, 1976381, 20126619, 21472111, 22430806, 23188440, 25393693, 2572268, 2576425, 26057454 View all (9 more)
Testicular Germ Cell Tumor	Associate	15330164, 16354586
Thrombocytopenia	Associate	37326930
Thymoma	Associate	17154178
Thymoma Familial	Associate	17154178
Thymus Neoplasms	Associate	37749819
Thyroid Cancer Papillary	Associate	1352125, 23857157, 26810418, 27775641, 28730228, 28947799, 3390372, 39222604
Thyroid Cancer Papillary	Stimulate	27929428
Thyroid Carcinoma Anaplastic	Associate	25576899, 28489587
Thyroid Neoplasms	Associate	20237991, 27775641, 27929428, 33903625, 3390372, 34972706
Tn Syndrome	Associate	34217971
Tongue Neoplasms	Associate	17549665
Triple Negative Breast Neoplasms	Inhibit	17146782, 22006997, 22192147, 23039971, 23373898, 24008095, 25356777, 25973113, 26752006, 29875927, 30335837, 33057161, 33112563, 35603379, 35875026, 36188649, 37208678 View all (2 more)
Triple Negative Breast Neoplasms	Associate	18726992, 19372580, 19383352, 20189874, 21152100, 21357651, 21939527, 23135573, 23188436, 23334330, 23555923, 23892410, 24026994, 24086418, 24188694 View all (54 more)
Triple Negative Breast Neoplasms	Stimulate	26892105, 30733547, 34370552, 37824496
Turcot syndrome	Associate	35849120
Ulcer	Associate	32592354
Unilateral Breast Neoplasms	Stimulate	37761848
Uniparental Disomy	Associate	21152100
Urethral Neoplasms	Associate	12209684, 16286979, 16965395, 18006009, 20495743, 21516078, 23593348, 24186136, 24966967, 25720673, 26287187, 26320869, 26651075, 28388586, 28755093 View all (17 more)
Urethritis	Associate	16965395, 37793085
Urinary Bladder Diseases	Stimulate	25178641
Urinary Bladder Diseases	Associate	29941010
Urinary Bladder Neoplasms	Associate	12209684, 15583696, 15790699, 15816639, 16685269, 17361205, 18415713, 19889613, 22102915, 24186136, 24966967, 24971884, 25809292, 26240484, 27034533 View all (34 more)
Urinary Bladder Neoplasms	Stimulate	25712293
Urologic Neoplasms	Associate	20651405, 24065479, 24551292, 39739128
Uterine Cervical Dysplasia	Associate	31805897
Uterine Cervical Neoplasms	Associate	10190316, 11275796, 12366664, 1355495, 14675323, 15341668, 18629779, 20057287, 21633298, 23922932, 24390348, 29941010, 30018982, 31675687, 32107047 View all (5 more)
Uterine Cervical Neoplasms	Stimulate	25712293
Uterine Diseases	Associate	18567994
Uterine Neoplasms	Associate	15785748, 17009989, 33161227
Vascular Diseases	Associate	15734884
Virilism	Associate	11920466
Virus Diseases	Associate	22071781
Vitamin D Deficiency	Associate	29481024
Vulvar Neoplasms	Associate	16033092, 28877932, 31009269
Waardenburg syndrome type 2	Associate	36038884
Waldenstrom Macroglobulinemia	Associate	27034533
Wilms Tumor	Associate	19609744
Xanthomatosis Cerebrotendinous	Stimulate	18196606

ERBB2 (erb-b2 receptor tyrosine kinase 2)