EIF2S3 (eukaryotic translation initiation factor 2 subunit gamma)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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1968 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Eukaryotic translation initiation factor 2 subunit gamma |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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EIF2S3 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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EIF2, EIF2G, EIF2gamma, MEHMO, MRXSBRK, eIF-2gA, eIF2gX |
Disease Acronyms (UniProt)
Disease acronyms from UniProt database
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MEHMO |
Chromosome
Chromosome number
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X |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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Xp22.11 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene is the largest subunit of a heterotrimeric GTP-binding protein involved in the recruitment of methionyl-tRNA(i) to the 40 S ribosomal subunit. [provided by RefSeq, Jan 2010] |
SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||||||||||||
UniProt ID | P41091 | ||||||||||||||||||||
Protein name | Eukaryotic translation initiation factor 2 subunit 3 (EC 3.6.5.3) (Eukaryotic translation initiation factor 2 subunit gamma X) (eIF2-gamma X) (eIF2gX) | ||||||||||||||||||||
Protein function | Member of the eIF2 complex that functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA (PubMed:31836389). This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form the 43S | ||||||||||||||||||||
PDB | 6FEC , 6K71 , 6K72 , 6O81 , 6O85 , 6YBV , 6ZMW , 6ZP4 , 7A09 , 7D43 , 7F66 , 7F67 , 7QP6 , 7QP7 , 8OZ0 , 8PHD , 8PHV , 8PJ1 , 8PJ2 , 8PJ3 , 8PJ4 , 8PPL , 8QZZ | ||||||||||||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Expressed in testis, brain, liver and muscle. {ECO:0000269|PubMed:9736774}. | ||||||||||||||||||||
Sequence | |||||||||||||||||||||
Sequence length | 472 | ||||||||||||||||||||
Interactions | View interactions |