Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs Transcription factors Other IDs Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	1956
Gene name Gene Name - the full gene name approved by the HGNC.	Epidermal growth factor receptor
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	EGFR
Synonyms (NCBI Gene) Gene synonyms aliases	ERBB, ERBB1, ERRP, HER1, NISBD2, NNCIS, PIG61, mENA
Chromosome Chromosome number	7
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	7p11.2
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growt

Show/Hide all(76)

SNP ID	Visualize variation	Clinical significance	Consequence
rs28929495	G>A,C,T	Pathogenic, likely-pathogenic, not-provided, drug-response	Missense variant, genic downstream transcript variant, coding sequence variant
rs121434568	T>A,G	Drug-response, pathogenic, likely-pathogenic	Genic downstream transcript variant, missense variant, coding sequence variant
rs121913229	G>C	Uncertain-significance, likely-pathogenic	Genic downstream transcript variant, missense variant, coding sequence variant
rs121913231	C>T	Likely-pathogenic	Genic downstream transcript variant, missense variant, coding sequence variant
rs121913418	G>A,T	Uncertain-significance, likely-pathogenic	Genic downstream transcript variant, missense variant, coding sequence variant
rs121913420	G>A	Likely-pathogenic	Genic downstream transcript variant, missense variant, coding sequence variant
rs121913421	GGAATTAAGAGAAGC>-	Drug-response	Genic downstream transcript variant, inframe deletion, coding sequence variant
rs121913422	AATTAAGAGAAGCAACAT>-	Drug-response	Genic downstream transcript variant, inframe indel, coding sequence variant
rs121913424	AATTAAGAGAAGCAACATCT>TC	Drug-response	Genic downstream transcript variant, inframe indel, coding sequence variant
rs121913425	AATTAAGAGAAGCAA>-	Drug-response	Genic downstream transcript variant, inframe indel, coding sequence variant
rs121913427	G>A,C	Not-provided, likely-pathogenic	Genic downstream transcript variant, missense variant, coding sequence variant
rs121913428	G>A,C	Pathogenic, likely-pathogenic	Genic downstream transcript variant, missense variant, coding sequence variant
rs121913430	G>A	Likely-pathogenic	Genic downstream transcript variant, missense variant, coding sequence variant
rs121913433	A>G	Likely-pathogenic	Genic downstream transcript variant, missense variant, coding sequence variant
rs121913434	C>G,T	Drug-response	Genic downstream transcript variant, missense variant, coding sequence variant
rs121913435	ATTAAGAGAAG>GC	Drug-response	Genic downstream transcript variant, inframe indel, coding sequence variant
rs121913436	TTAAGAGAA>-	Drug-response	Genic downstream transcript variant, inframe deletion, coding sequence variant
rs121913438	TAAGAGAAGCAACATCTC>-	Drug-response	Genic downstream transcript variant, inframe indel, coding sequence variant
rs121913440	TTAAGAGAAGCAACATCT>-	Drug-response	Genic downstream transcript variant, inframe deletion, coding sequence variant
rs121913442	TAAGAGAAGCAACAT>-	Drug-response	Genic downstream transcript variant, inframe deletion, coding sequence variant
rs121913443	C>A,T	Likely-benign, uncertain-significance, likely-pathogenic	Genic downstream transcript variant, synonymous variant, missense variant, coding sequence variant
rs121913444	T>A,C,G	Uncertain-significance, drug-response, pathogenic, likely-pathogenic	Genic downstream transcript variant, missense variant, coding sequence variant
rs121913446	C>T	Likely-pathogenic	Genic downstream transcript variant, missense variant, coding sequence variant
rs121913463	TCTCCGAAAGCCAACAAGGAAATC>-	Drug-response	Genic downstream transcript variant, inframe deletion, coding sequence variant
rs121913464	C>A	Likely-pathogenic	Genic downstream transcript variant, missense variant, coding sequence variant
rs121913466	T>C	Likely-pathogenic	Genic downstream transcript variant, missense variant, coding sequence variant
rs121913467	G>A	Likely-pathogenic	Genic downstream transcript variant, coding sequence variant, stop gained
rs139236063	G>C,T	Likely-pathogenic	Genic downstream transcript variant, missense variant, coding sequence variant
rs139429793	G>A	Pathogenic	Missense variant, coding sequence variant
rs146795390	G>A	Likely-pathogenic	Genic downstream transcript variant, coding sequence variant, missense variant
rs149840192	C>A,T	Likely-pathogenic	Coding sequence variant, intron variant, missense variant
rs150036236	G>A	Pathogenic	Coding sequence variant, missense variant, genic downstream transcript variant
rs397509368	TTAAGAGAAGCAA>C	Drug-response	Genic downstream transcript variant, coding sequence variant, inframe indel
rs397517085	A>C,G,T	Drug-response, uncertain-significance	Missense variant, genic downstream transcript variant, coding sequence variant
rs397517086	AAC>-	Pathogenic	Genic downstream transcript variant, coding sequence variant, inframe indel
rs397517094	CAAGGAATTAAGAGAAGC>AAA	Likely-pathogenic	Genic downstream transcript variant, inframe deletion, coding sequence variant
rs397517097	T>C	Likely-pathogenic, uncertain-significance	Missense variant, genic downstream transcript variant, coding sequence variant
rs397517098	TAAGAGAAG>-	Likely-pathogenic	Genic downstream transcript variant, coding sequence variant, inframe indel
rs397517127	G>C,T	Pathogenic, uncertain-significance	Missense variant, genic downstream transcript variant, coding sequence variant
rs483352805	G>A	Drug-response	Genic downstream transcript variant, missense variant, coding sequence variant
rs483352808	G>A	Drug-response	Genic downstream transcript variant, missense variant, coding sequence variant
rs606231253	G>A	Pathogenic	Coding sequence variant, missense variant, genic downstream transcript variant
rs727503014	ATCAAGGAATTAAGAGAAGC>GTCAA	Drug-response	Coding sequence variant, inframe indel, genic downstream transcript variant
rs727503015	AATTAAGAGAAG>CAC,CCC	Drug-response	Coding sequence variant, inframe indel, genic downstream transcript variant
rs727503016	AATTAAGAGAAGCAA>TTC	Drug-response	Coding sequence variant, inframe indel, genic downstream transcript variant
rs727504232	ATCTCCGAAAGCCAACAAGGAAAT>-	Drug-response	Coding sequence variant, genic downstream transcript variant, inframe deletion
rs727504233	GAATTAAGAGAAGCA>-	Drug-response	Coding sequence variant, genic downstream transcript variant, inframe deletion
rs727504256	G>A	Drug-response	Coding sequence variant, missense variant, genic downstream transcript variant
rs727504257	ATTAAGAGAAGCAA>GC	Drug-response	Coding sequence variant, inframe indel, genic downstream transcript variant
rs727504258	AATTAAGAGAAGCAACATC>T	Drug-response	Coding sequence variant, inframe indel, genic downstream transcript variant
rs727504266	GGAATTAAG>-	Drug-response	Coding sequence variant, genic downstream transcript variant, inframe deletion
rs727504278	TTAAGAGAAG>C	Drug-response	Coding sequence variant, inframe indel, genic downstream transcript variant
rs727504281	GGAATTAAGAGAAG>AATTC	Drug-response	Coding sequence variant, inframe indel, genic downstream transcript variant
rs727504282	AATTAAGAGAAGCAACATCTC>TCT	Drug-response	Coding sequence variant, inframe indel, genic downstream transcript variant
rs727504316	C>T	Drug-response	Coding sequence variant, missense variant, genic downstream transcript variant
rs727504324	CAAGGAATTAAGAGAAGCA>-	Drug-response	Coding sequence variant, frameshift variant, genic downstream transcript variant
rs727504326	->AAAATTCCCGTCGCTA	Drug-response	Coding sequence variant, frameshift variant, genic downstream transcript variant
rs727504332	GGAATTAAGAGAAGCAA>AATTC	Drug-response	Coding sequence variant, inframe indel, genic downstream transcript variant
rs727504339	TTAAGAGAAGCAACATCTC>A,CAAT	Drug-response	Coding sequence variant, inframe indel, genic downstream transcript variant
rs727504395	ACATCTCCGAAAGCCAACAAGGAAATC>GAT	Drug-response	Coding sequence variant, inframe indel, genic downstream transcript variant
rs727504402	GAATTAAGAGAAGCAAC>AT	Drug-response	Coding sequence variant, inframe indel, genic downstream transcript variant
rs727504414	TTAAGAGAAGCAACATCTCCGAAAGC>ACGAGAGA	Drug-response	Coding sequence variant, inframe indel, genic downstream transcript variant
rs727504428	CAAGGAATTAAGAGAAGCAAC>AAAGTT	Drug-response	Coding sequence variant, inframe indel, genic downstream transcript variant
rs727504444	AATTAAGAGA>C	Drug-response	Coding sequence variant, inframe indel, genic downstream transcript variant
rs769696078	G>A	Likely-pathogenic	Coding sequence variant, intron variant, missense variant
rs886037891	G>T	Pathogenic	Missense variant, coding sequence variant
rs909905659	G>A,T	Likely-pathogenic	Genic downstream transcript variant, missense variant, stop gained, coding sequence variant, intron variant
rs1057519760	A>G	Likely-pathogenic	Missense variant, genic downstream transcript variant, coding sequence variant
rs1057519794	G>A	Likely-pathogenic	Missense variant, genic downstream transcript variant, coding sequence variant
rs1057519828	G>A	Likely-pathogenic	Missense variant, coding sequence variant, intron variant
rs1057519829	A>C,G	Likely-pathogenic	Missense variant, coding sequence variant, intron variant
rs1057519830	C>T	Likely-pathogenic	Missense variant, genic downstream transcript variant, coding sequence variant
rs1057519848	TG>GT	Likely-pathogenic	Missense variant, genic downstream transcript variant, coding sequence variant
rs1057519887	GC>AA,AT	Likely-pathogenic	Missense variant, coding sequence variant, intron variant
rs1057519888	A>G	Likely-pathogenic	Missense variant, coding sequence variant, intron variant
rs1057520037	G>C	Likely-pathogenic	Missense variant, genic downstream transcript variant, coding sequence variant

Show/Hide all(248)

miRTarBase ID	miRNA	Experiments	Reference
MIRT002289	hsa-miR-7-5p	real-time RT-PCR, Reporter assay, Western blot	18483236
MIRT002289	hsa-miR-7-5p	Luciferase reporter assay	18483236
MIRT002289	hsa-miR-7-5p	Luciferase reporter assay	18483236
MIRT002289	hsa-miR-7-5p	Luciferase reporter assay	18483236
MIRT002289	hsa-miR-7-5p	Western blot	18483236
MIRT006585	hsa-miR-128-3p	Luciferase reporter assay	18304967
MIRT002289	hsa-miR-7-5p	Luciferase reporter assay	19033458
MIRT002289	hsa-miR-7-5p	Luciferase reporter assay	19029026
MIRT002289	hsa-miR-7-5p	Luciferase reporter assay	18483236
MIRT006585	hsa-miR-128-3p	Review	20130964
MIRT003325	hsa-miR-145-5p	Review	20026422
MIRT004730	hsa-miR-146a-5p	qRT-PCR, Western blot	20124483
MIRT001470	hsa-miR-16-5p	pSILAC	18668040
MIRT001370	hsa-miR-1-3p	pSILAC	18668040
MIRT002289	hsa-miR-7-5p	Luciferase reporter assay, qRT-PCR, Western blot	19073608
MIRT002289	hsa-miR-7-5p	Luciferase reporter assay, qRT-PCR, Western blot	19073608
MIRT002289	hsa-miR-7-5p	Luciferase reporter assay, qRT-PCR, Western blot	19073608
MIRT002289	hsa-miR-7-5p	Luciferase reporter assay, qRT-PCR, Western blot	19073608
MIRT002289	hsa-miR-7-5p	Luciferase reporter assay, qRT-PCR, Western blot	19073608
MIRT002289	hsa-miR-7-5p	Luciferase reporter assay, qRT-PCR, Western blot	19073608
MIRT005807	hsa-miR-21-5p	Luciferase reporter assay, Microarray, Western blot	20864407
MIRT002289	hsa-miR-7-5p	Luciferase reporter assay, Microarray, Western blot	20864407
MIRT006330	hsa-miR-542-5p	Luciferase reporter assay, qRT-PCR, Western blot	22426479
MIRT004730	hsa-miR-146a-5p	Luciferase reporter assay, Western blot	21632853
MIRT004730	hsa-miR-146a-5p	Luciferase reporter assay, Western blot	21632853
MIRT006330	hsa-miR-542-5p	Luciferase reporter assay, qRT-PCR, Western blot	22426479
MIRT004730	hsa-miR-146a-5p	Luciferase reporter assay, qRT-PCR, Western blot	22161865
MIRT004730	hsa-miR-146a-5p	Luciferase reporter assay, Western blot	21632853
MIRT006330	hsa-miR-542-5p	Luciferase reporter assay, qRT-PCR, Western blot	22426479
MIRT004730	hsa-miR-146a-5p	Luciferase reporter assay, qRT-PCR, Western blot	22161865
MIRT003325	hsa-miR-145-5p	Microarray, qRT-PCR, Western blot	21289483
MIRT007032	hsa-miR-133a-3p	Luciferase reporter assay	23069713
MIRT007069	hsa-miR-133b	Flow, In situ hybridization, Luciferase reporter assay, qRT-PCR, Western blot	22883469
MIRT007360	hsa-miR-27a-3p	Luciferase reporter assay	23559009
MIRT018378	hsa-miR-335-5p	Microarray	18185580
MIRT020911	hsa-miR-155-5p	Proteomics	18668040
MIRT004730	hsa-miR-146a-5p	Western blot	19190326
MIRT001370	hsa-miR-1-3p	Proteomics;Other	18668040
MIRT002289	hsa-miR-7-5p	Microarray	17612493
MIRT002289	hsa-miR-7-5p	Reporter assay;Western blot;qRT-PCR;Other	18483236
MIRT002289	hsa-miR-7-5p	Reporter assay;Western blot;qRT-PCR;Microarray;Other	19073608
MIRT028600	hsa-miR-30a-5p	Proteomics	18668040
MIRT005807	hsa-miR-21-5p	Western blot;Other	20048743
MIRT001470	hsa-miR-16-5p	Proteomics;Other	18668040
MIRT002289	hsa-miR-7-5p	Western blot	22853714
MIRT004353	hsa-miR-128-3p	Western blot	22853714
MIRT035541	hsa-let-7a-5p	Luciferase reporter assay	23032975
MIRT036702	hsa-miR-301b-3p	CLASH	23622248
MIRT007069	hsa-miR-133b	Luciferase reporter assay, Western blot	22407299
MIRT007069	hsa-miR-133b	Luciferase reporter assay, Western blot	22407299
MIRT007032	hsa-miR-133a-3p	Luciferase reporter assay, Western blot	22407299
MIRT007032	hsa-miR-133a-3p	Luciferase reporter assay, Western blot	22407299
MIRT002289	hsa-miR-7-5p	Immunohistochemistry, In situ hybridization, qRT-PCR, Western blot	24816687
MIRT007032	hsa-miR-133a-3p	Luciferase reporter assay, qRT-PCR	24816813
MIRT007360	hsa-miR-27a-3p	Luciferase reporter assay, qRT-PCR, Western blot	23650389
MIRT007360	hsa-miR-27a-3p	Luciferase reporter assay, qRT-PCR, Western blot	23650389
MIRT007360	hsa-miR-27a-3p	Luciferase reporter assay, qRT-PCR, Western blot	23650389
MIRT007360	hsa-miR-27a-3p	Luciferase reporter assay, qRT-PCR, Western blot	23650389
MIRT007032	hsa-miR-133a-3p	Flow, Luciferase reporter assay, qRT-PCR, Western blot	23786162
MIRT002289	hsa-miR-7-5p	Luciferase reporter assay, Microarray, qRT-PCR, Western blot	23115635
MIRT002289	hsa-miR-7-5p	Luciferase reporter assay, Microarray, qRT-PCR, Western blot	24573489
MIRT002289	hsa-miR-7-5p	Luciferase reporter assay, Microarray, qRT-PCR, Western blot	24573489
MIRT002289	hsa-miR-7-5p	Luciferase reporter assay, Microarray, qRT-PCR, Western blot	24573489
MIRT054243	hsa-miR-574-3p	Luciferase reporter assay, Microarray, qRT-PCR, Western blot	23554959
MIRT004730	hsa-miR-146a-5p	Western blot, qRT-PCR	23555954
MIRT054487	hsa-miR-219a-5p	Luciferase reporter assay, Microarray, Western blot, qRT-PCR	23690991
MIRT054487	hsa-miR-219a-5p	Luciferase reporter assay, Microarray, Western blot, qRT-PCR	23690991
MIRT054661	hsa-miR-302b-3p	Luciferase reporter assay, qRT-PCR, Western blot	24083596
MIRT054661	hsa-miR-302b-3p	Luciferase reporter assay, qRT-PCR, Western blot	24083596
MIRT004730	hsa-miR-146a-5p	Luciferase reporter assay, QRTPCR, Western blot	24839931
MIRT054888	hsa-miR-125a-5p	qRT-PCR, Western blot	24484870
MIRT002289	hsa-miR-7-5p	Luciferase reporter assay	23319046
MIRT002289	hsa-miR-7-5p	Luciferase reporter assay	23319046
MIRT002289	hsa-miR-7-5p	Flow, qRT-PCR, Western blot	24134702
MIRT002289	hsa-miR-7-5p	Flow, qRT-PCR, Western blot	24134702
MIRT002289	hsa-miR-7-5p	Flow, qRT-PCR, Western blot	24134702
MIRT438024	hsa-miR-218-5p	Luciferase reporter assay	24368849
MIRT002289	hsa-miR-7-5p	Flow, qRT-PCR, Western blot	24134702
MIRT002289	hsa-miR-7-5p	Flow, qRT-PCR, Western blot	24134702
MIRT002289	hsa-miR-7-5p	Flow, qRT-PCR, Western blot	24134702
MIRT438024	hsa-miR-218-5p	Luciferase reporter assay	24368849
MIRT438024	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT438024	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT002289	hsa-miR-7-5p	Luciferase reporter assay, qRT-PCR, Western blot	25475098
MIRT002289	hsa-miR-7-5p	Luciferase reporter assay, qRT-PCR, Western blot	25475098
MIRT002289	hsa-miR-7-5p	Luciferase reporter assay, qRT-PCR, Western blot	25475098
MIRT002289	hsa-miR-7-5p	Luciferase reporter assay, qRT-PCR, Western blot	25475098
MIRT007069	hsa-miR-133b	Luciferase reporter assay, Western blot	26617770
MIRT007069	hsa-miR-133b	Luciferase reporter assay, Western blot	26617770
MIRT731611	hsa-miR-2861	Luciferase reporter assay, Western blot	27364926
MIRT731611	hsa-miR-2861	Luciferase reporter assay, Western blot	27364926
MIRT007032	hsa-miR-133a-3p	Luciferase reporter assay, Western blot	26134491
MIRT007032	hsa-miR-133a-3p	Luciferase reporter assay, Western blot	26134491
MIRT731713	hsa-miR-132-3p	Immunohistochemistry, Luciferase reporter assay, qRT-PCR, Western blot	26452132
MIRT731713	hsa-miR-132-3p	Immunohistochemistry, Luciferase reporter assay, qRT-PCR, Western blot	26452132
MIRT731713	hsa-miR-132-3p	Immunohistochemistry, Luciferase reporter assay, qRT-PCR, Western blot	26452132
MIRT731713	hsa-miR-132-3p	Immunohistochemistry, Luciferase reporter assay, qRT-PCR, Western blot	26452132
MIRT732238	hsa-miR-875-5p	Luciferase reporter assay, Western blot	27302926
MIRT732238	hsa-miR-875-5p	Luciferase reporter assay, Western blot	27302926
MIRT732244	hsa-miR-7-1-3p	Microarray, qRT-PCR, Western blot	27448964
MIRT732244	hsa-miR-7-1-3p	Microarray, qRT-PCR, Western blot	27448964
MIRT004730	hsa-miR-146a-5p	Immunohistochemistry, Luciferase reporter assay, qRT-PCR, Western blot	27818285
MIRT732238	hsa-miR-875-5p	Immunofluorescence, Luciferase reporter assay, qRT-PCR, Western blot	28274892
MIRT737367	hsa-miR-3622b-5p	Luciferase reporter assay	27611943
MIRT737367	hsa-miR-3622b-5p	Luciferase reporter assay	27611943
MIRT737367	hsa-miR-3622b-5p	Luciferase reporter assay	27611943
MIRT737367	hsa-miR-3622b-5p	Luciferase reporter assay	27611943
MIRT737367	hsa-miR-3622b-5p	Luciferase reporter assay	27611943
MIRT737367	hsa-miR-3622b-5p	Luciferase reporter assay	27611943
MIRT438024	hsa-miR-218-5p	Luciferase reporter assay, qRT-PCR, Western blot	27057632
MIRT438024	hsa-miR-218-5p	Luciferase reporter assay, qRT-PCR, Western blot	27057632
MIRT438024	hsa-miR-218-5p	Luciferase reporter assay, qRT-PCR, Western blot	27057632
MIRT734664	hsa-miR-133a-5p	Western blot	27465833
MIRT737349	hsa-miR-137	Luciferase reporter assay, Western blot	28386374
MIRT737349	hsa-miR-137	Luciferase reporter assay, Western blot	28386374
MIRT020911	hsa-miR-155-5p	Immunofluorescence, Luciferase reporter assay, Microarray, qRT-PCR, Western blotting	33474615
MIRT732647	hsa-miR-608	qRT-PCR	33523578
MIRT733293	hsa-miR-128-2-5p	Immunohistochemistry (IHC), qRT-PCR	31638205
MIRT005807	hsa-miR-21-3p	qRT-PCR	34208765
MIRT007360	hsa-miR-27a-3p	qRT-PCR	34208765
MIRT733417	hsa-miR-181a-5p	qRT-PCR	34208765
MIRT733444	hsa-miR-200b-3p	Luciferase reporter assay, qRT-PCR, Western blotting	32708220
MIRT054487	hsa-miR-219a-5p	Immunofluorescence, qRT-PCR, Western blotting	34113391
MIRT733741	hsa-miR-646	Luciferase reporter assay, Microarray, qRT-PCR, Western blotting	33335643
MIRT004730	hsa-miR-146a-5p	Luciferase reporter assay, qRT-PCR, Western blotting	33317606
MIRT734078	hsa-miR-557	Luciferase reporter assay, Microarray, qRT-PCR, Western blotting	31933947
MIRT734109	hsa-miR-138-5p	Luciferase reporter assay, Western blotting, Immunohistochemistry (IHC), qRT-PCR, Flow cytometry	33209893
MIRT007032	hsa-miR-133a-3p	Luciferase reporter assay, qRT-PCR, Western blotting	32764884
MIRT734189	hsa-miR-634	ELISA, Immunofluorescence, Luciferase reporter assay, qRT-PCR, Western blotting	33294587
MIRT734191	hsa-miR-3934-5p	FACS, Microarray, Western blotting	33605506
MIRT004730	hsa-miR-146a-5p	Immunofluorescence, Immunohistochemistry (IHC), Luciferase reporter assay, qRT-PCR, Western blotting	33317606
MIRT734664	hsa-miR-133a-5p	Luciferase reporter assay	31736422
MIRT734684	hsa-miR-21-3p	Microarray, ELISA	31727077
MIRT734685	hsa-miR-146a-3p	Microarray, ELISA	31727077
MIRT734686	hsa-miR-146b-3p	Microarray, ELISA	31727077
MIRT054243	hsa-miR-574-3p	qRT-PCR	33194623
MIRT006330	hsa-miR-542-5p	qRT-PCR, Flow cytometry	33173276
MIRT007069	hsa-miR-133b	Immunohistochemistry (IHC), qRT-PCR, ELISA	33211633
MIRT736365	hsa-miR-486-3p	Luciferase reporter assay, Western blotting, Immunohistochemistry (IHC), qRT-PCR	32313144
MIRT736523	hsa-miR-193a-3p	Luciferase reporter assay, Western blotting	34288281
MIRT002289	hsa-miR-7-5p	Western blotting, qRT-PCR	32592373
MIRT054888	hsa-miR-125a-5p	Western blotting, qRT-PCR	34081797
MIRT736883	hsa-miR-145-3p	Western blotting, qRT-PCR	34081797
MIRT736883	hsa-miR-145-3p	qRT-PCR	31554377
MIRT054888	hsa-miR-125a-5p	qRT-PCR, ELISA	31759360
MIRT736974	hsa-miR-802	Luciferase reporter assay, Western blotting, Immunohistochemistry (IHC), Translational profiling, in vitro cullelar assays, qRT-PCR, in vivo gain/loss-of-function experiments	32210368
MIRT736982	hsa-miR-4328	Microarray, Immunohistochemistry (IHC)	32170146
MIRT736523	hsa-miR-193a-3p	Luciferase reporter assay, Western blotting, Flow cytometry	34288281
MIRT737297	hsa-miR-9-3p	Luciferase reporter assay, Western blotting, qRT-PCR	32772818
MIRT737349	hsa-miR-137	Western blotting, Microarray, qRT-PCR, Flow cytometry, ELISA	32627038
MIRT737365	hsa-miR-200c-3p	Western blotting, RNA-seq, qRT-PCR	32417760
MIRT737367	hsa-miR-3622b-5p	Luciferase reporter assay, Western blotting, RNA-seq	32371581
MIRT007360	hsa-miR-27a-3p	Luciferase reporter assay, Western blotting, qRT-PCR	32039029
MIRT756070	hsa-miR-377-3p	Luciferase reporter assay, qRT-PCR	34668101
MIRT756387	hsa-miR-370-3p	Luciferase reporter assay, Western blotting, qRT-PCR, Immunoprecipitaion (IP)	34618022
MIRT954740	hsa-miR-103a	CLIP-seq
MIRT954741	hsa-miR-107	CLIP-seq
MIRT954742	hsa-miR-1183	CLIP-seq
MIRT954743	hsa-miR-1275	CLIP-seq
MIRT954744	hsa-miR-1323	CLIP-seq
MIRT954745	hsa-miR-2277-3p	CLIP-seq
MIRT954746	hsa-miR-2278	CLIP-seq
MIRT954747	hsa-miR-3120-3p	CLIP-seq
MIRT954748	hsa-miR-3129-3p	CLIP-seq
MIRT954749	hsa-miR-3144-5p	CLIP-seq
MIRT954750	hsa-miR-3150a-3p	CLIP-seq
MIRT954751	hsa-miR-3170	CLIP-seq
MIRT954752	hsa-miR-3175	CLIP-seq
MIRT954753	hsa-miR-3191	CLIP-seq
MIRT954754	hsa-miR-342-5p	CLIP-seq
MIRT954755	hsa-miR-3647-3p	CLIP-seq
MIRT954756	hsa-miR-3929	CLIP-seq
MIRT954757	hsa-miR-3942-3p	CLIP-seq
MIRT954758	hsa-miR-4260	CLIP-seq
MIRT954759	hsa-miR-4261	CLIP-seq
MIRT954760	hsa-miR-433	CLIP-seq
MIRT954761	hsa-miR-4419b	CLIP-seq
MIRT954762	hsa-miR-4428	CLIP-seq
MIRT954763	hsa-miR-4478	CLIP-seq
MIRT954764	hsa-miR-4509	CLIP-seq
MIRT954765	hsa-miR-451b	CLIP-seq
MIRT954766	hsa-miR-4651	CLIP-seq
MIRT954767	hsa-miR-4652-5p	CLIP-seq
MIRT954768	hsa-miR-4664-5p	CLIP-seq
MIRT954769	hsa-miR-4665-5p	CLIP-seq
MIRT954770	hsa-miR-4682	CLIP-seq
MIRT954771	hsa-miR-4688	CLIP-seq
MIRT954772	hsa-miR-4696	CLIP-seq
MIRT954773	hsa-miR-4735-5p	CLIP-seq
MIRT954774	hsa-miR-4775	CLIP-seq
MIRT954775	hsa-miR-4803	CLIP-seq
MIRT954776	hsa-miR-548o	CLIP-seq
MIRT954777	hsa-miR-590-3p	CLIP-seq
MIRT954778	hsa-miR-607	CLIP-seq
MIRT954779	hsa-miR-875-3p	CLIP-seq
MIRT954780	hsa-miR-939	CLIP-seq
MIRT954781	hsa-miR-4436a	CLIP-seq
MIRT1982758	hsa-miR-105	CLIP-seq
MIRT1982759	hsa-miR-128	CLIP-seq
MIRT1982760	hsa-miR-133a	CLIP-seq
MIRT954746	hsa-miR-2278	CLIP-seq
MIRT1982761	hsa-miR-27a	CLIP-seq
MIRT1982762	hsa-miR-27b	CLIP-seq
MIRT1982763	hsa-miR-3136-5p	CLIP-seq
MIRT1982764	hsa-miR-3674	CLIP-seq
MIRT954757	hsa-miR-3942-3p	CLIP-seq
MIRT954762	hsa-miR-4428	CLIP-seq
MIRT1982765	hsa-miR-4439	CLIP-seq
MIRT1982766	hsa-miR-4502	CLIP-seq
MIRT1982767	hsa-miR-4513	CLIP-seq
MIRT1982768	hsa-miR-4728-3p	CLIP-seq
MIRT1982769	hsa-miR-579	CLIP-seq
MIRT1982770	hsa-miR-622	CLIP-seq
MIRT1982758	hsa-miR-105	CLIP-seq
MIRT1982759	hsa-miR-128	CLIP-seq
MIRT2217637	hsa-miR-1587	CLIP-seq
MIRT1982761	hsa-miR-27a	CLIP-seq
MIRT1982762	hsa-miR-27b	CLIP-seq
MIRT2217638	hsa-miR-299-3p	CLIP-seq
MIRT2217639	hsa-miR-3147	CLIP-seq
MIRT2217640	hsa-miR-3652	CLIP-seq
MIRT2217641	hsa-miR-3977	CLIP-seq
MIRT2217642	hsa-miR-4253	CLIP-seq
MIRT2217643	hsa-miR-4265	CLIP-seq
MIRT2217644	hsa-miR-4296	CLIP-seq
MIRT2217645	hsa-miR-4322	CLIP-seq
MIRT2217646	hsa-miR-4417	CLIP-seq
MIRT2217647	hsa-miR-4425	CLIP-seq
MIRT2217648	hsa-miR-4430	CLIP-seq
MIRT2217649	hsa-miR-4492	CLIP-seq
MIRT2217650	hsa-miR-4498	CLIP-seq
MIRT2217651	hsa-miR-450b-3p	CLIP-seq
MIRT2217652	hsa-miR-4656	CLIP-seq
MIRT2217653	hsa-miR-4675	CLIP-seq
MIRT2217654	hsa-miR-4687-3p	CLIP-seq
MIRT2217655	hsa-miR-4709-3p	CLIP-seq
MIRT2217656	hsa-miR-4741	CLIP-seq
MIRT2217657	hsa-miR-4767	CLIP-seq
MIRT2217658	hsa-miR-502-5p	CLIP-seq
MIRT2217659	hsa-miR-513a-5p	CLIP-seq
MIRT2217660	hsa-miR-762	CLIP-seq
MIRT2217661	hsa-miR-769-3p	CLIP-seq
MIRT2387248	hsa-miR-1269	CLIP-seq
MIRT2387249	hsa-miR-1269b	CLIP-seq
MIRT2387250	hsa-miR-1288	CLIP-seq
MIRT2387251	hsa-miR-4515	CLIP-seq
MIRT2387252	hsa-miR-4740-5p	CLIP-seq
MIRT2387253	hsa-miR-4788	CLIP-seq

Transcription factors

Show/Hide all(33)

Transcription factor	Regulation	Reference
AR	Activation	11556855;21613411
BCL3	Activation	17881446
BRCA1	Repression	21396117
CREBBP	Unknown	21464950
EGR1	Activation	11830539
ESR1	Unknown	12421825
HDAC1	Repression	22025675
HDAC3	Unknown	21464950
HOXB7	Activation	21690342
JUN	Activation	10803405
JUNB	Activation	10803405
KLF10	Repression	22025675
LRRFIP1	Repression	14522076
MTA1	Activation	11948399
NFKB1	Activation	17881446
NFKB1	Unknown	14678988
NR3C2	Activation	17692454
PGR	Unknown	22542550
PML	Repression	12673202;9819401
PPARG	Repression	15486348
RELA	Activation	17881446
SP1	Repression	18202149
SP1	Unknown	10830317;18575762;19538880;21464950
STAT1	Unknown	10558875;22693070
STAT3	Activation	21590492;23504318
TFAP2A	Unknown	8621697
TP53	Activation	10029407
TSG101	Repression	19154774
VDR	Repression	16087726
VDR	Unknown	15218361
WT1	Repression	9291179
YBX1	Activation	17875215;19648825
YY1	Activation	22580610

Show/Hide all(156)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IEA
GO:0000165	Process	MAPK cascade	IEA
GO:0000166	Function	Nucleotide binding	IEA
GO:0000902	Process	Cell morphogenesis	IEA
GO:0001503	Process	Ossification	NAS	12925580
GO:0001618	Function	Virus receptor activity	IEA
GO:0001892	Process	Embryonic placenta development	IEA
GO:0001934	Process	Positive regulation of protein phosphorylation	IDA	20551055
GO:0001942	Process	Hair follicle development	IEA
GO:0003682	Function	Chromatin binding	IDA	20551055
GO:0003690	Function	Double-stranded DNA binding	NAS	6325948
GO:0004672	Function	Protein kinase activity	IEA
GO:0004709	Function	MAP kinase kinase kinase activity	NAS	15542601
GO:0004713	Function	Protein tyrosine kinase activity	IDA	2472218, 9890893, 17115032, 17599051
GO:0004713	Function	Protein tyrosine kinase activity	IEA
GO:0004713	Function	Protein tyrosine kinase activity	IMP	14702346, 20878056
GO:0004713	Function	Protein tyrosine kinase activity	TAS	16076471
GO:0004714	Function	Transmembrane receptor protein tyrosine kinase activity	IBA
GO:0004714	Function	Transmembrane receptor protein tyrosine kinase activity	IEA
GO:0004714	Function	Transmembrane receptor protein tyrosine kinase activity	TAS
GO:0004888	Function	Transmembrane signaling receptor activity	IDA	7736574
GO:0005006	Function	Epidermal growth factor receptor activity	IDA	12828935
GO:0005006	Function	Epidermal growth factor receptor activity	IDA	2176151, 11336639, 12435727, 17115032
GO:0005006	Function	Epidermal growth factor receptor activity	IEA
GO:0005006	Function	Epidermal growth factor receptor activity	IMP	22732145
GO:0005006	Function	Epidermal growth factor receptor activity	NAS	2790960, 6325948
GO:0005515	Function	Protein binding	IPI	2176151, 2790960, 7518560, 7542744, 7657591, 7685104, 7693694, 7797556, 7993895, 8034616, 8305738, 8621392, 8887653, 8940013, 9020117, 9050838, 9135143, 9355745, 9419975, 9506989, 9544989, 9852145, 10026169, 10229072, 10572067, 10805725, 11279102, 11896612, 12070153, 12297049, 1229705
GO:0005524	Function	ATP binding	IEA
GO:0005576	Component	Extracellular region	IEA
GO:0005615	Component	Extracellular space	NAS	9103388
GO:0005634	Component	Nucleus	IDA	12828935, 17115032, 20551055
GO:0005634	Component	Nucleus	IEA
GO:0005737	Component	Cytoplasm	IDA	7588596, 12435727, 22298428
GO:0005768	Component	Endosome	IDA	16554368
GO:0005768	Component	Endosome	IDA	14702346, 17182860, 22732145
GO:0005768	Component	Endosome	IEA
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0005794	Component	Golgi apparatus	IDA
GO:0005794	Component	Golgi apparatus	IEA
GO:0005829	Component	Cytosol	IDA
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IDA	11331309, 11336639, 15611079
GO:0005886	Component	Plasma membrane	IDA	15465819, 20462955, 22298428, 22732145
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0005925	Component	Focal adhesion	HDA	21423176
GO:0005929	Component	Cilium	IDA
GO:0007165	Process	Signal transduction	IDA	10572067
GO:0007165	Process	Signal transduction	IEA
GO:0007165	Process	Signal transduction	TAS
GO:0007166	Process	Cell surface receptor signaling pathway	IDA	7736574
GO:0007169	Process	Cell surface receptor protein tyrosine kinase signaling pathway	IEA
GO:0007173	Process	Epidermal growth factor receptor signaling pathway	IBA
GO:0007173	Process	Epidermal growth factor receptor signaling pathway	IDA	7736574, 8663461
GO:0007173	Process	Epidermal growth factor receptor signaling pathway	IDA	9890893, 12435727, 12828935, 24854121
GO:0007173	Process	Epidermal growth factor receptor signaling pathway	IEA
GO:0007173	Process	Epidermal growth factor receptor signaling pathway	IMP	8253073
GO:0007173	Process	Epidermal growth factor receptor signaling pathway	IMP	17655843, 18483258, 20878056
GO:0007173	Process	Epidermal growth factor receptor signaling pathway	TAS
GO:0007435	Process	Salivary gland morphogenesis	IEA
GO:0007611	Process	Learning or memory	ISS
GO:0008283	Process	Cell population proliferation	IEA
GO:0008284	Process	Positive regulation of cell population proliferation	IDA	7736574
GO:0008284	Process	Positive regulation of cell population proliferation	IEA
GO:0008284	Process	Positive regulation of cell population proliferation	IMP	27057632
GO:0008544	Process	Epidermis development	IEA
GO:0009925	Component	Basal plasma membrane	IBA
GO:0009986	Component	Cell surface	IDA	25666625
GO:0009986	Component	Cell surface	IEA
GO:0010008	Component	Endosome membrane	IDA	22719997
GO:0010008	Component	Endosome membrane	IEA
GO:0010008	Component	Endosome membrane	TAS
GO:0016020	Component	Membrane	IDA	12435727
GO:0016020	Component	Membrane	IEA
GO:0016301	Function	Kinase activity	IEA
GO:0016323	Component	Basolateral plasma membrane	IDA	12646923
GO:0016323	Component	Basolateral plasma membrane	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0019899	Function	Enzyme binding	IPI	12009895
GO:0019900	Function	Kinase binding	IPI	18722344, 22732145
GO:0019903	Function	Protein phosphatase binding	IPI	15899872, 28759036
GO:0021795	Process	Cerebral cortex cell migration	IEA
GO:0030054	Component	Cell junction	IDA
GO:0030139	Component	Endocytic vesicle	IEA
GO:0030182	Process	Neuron differentiation	IBA
GO:0030296	Function	Protein tyrosine kinase activator activity	IDA	2176151, 11336639
GO:0030307	Process	Positive regulation of cell growth	IDA	15467833
GO:0030335	Process	Positive regulation of cell migration	IMP	12435727, 25678558
GO:0030669	Component	Clathrin-coated endocytic vesicle membrane	TAS
GO:0031625	Function	Ubiquitin protein ligase binding	IPI	23418353
GO:0031901	Component	Early endosome membrane	IDA	17714434
GO:0031965	Component	Nuclear membrane	IEA
GO:0032587	Component	Ruffle membrane	IDA	11331309
GO:0032991	Component	Protein-containing complex	IDA	20878056
GO:0033138	Process	Positive regulation of peptidyl-serine phosphorylation	IMP	20878056
GO:0036064	Component	Ciliary basal body	IDA
GO:0038134	Process	ERBB2-EGFR signaling pathway	IDA	11336639
GO:0038134	Process	ERBB2-EGFR signaling pathway	IEA
GO:0042059	Process	Negative regulation of epidermal growth factor receptor signaling pathway	IEA
GO:0042059	Process	Negative regulation of epidermal growth factor receptor signaling pathway	TAS
GO:0042127	Process	Regulation of cell population proliferation	IEA
GO:0042177	Process	Negative regulation of protein catabolic process	IDA	17115032
GO:0042327	Process	Positive regulation of phosphorylation	IDA	15082764
GO:0042802	Function	Identical protein binding	IPI	16777603, 17148612, 18042729, 19563760, 19650109, 20007378, 20029029, 20359299, 21278786, 21480528, 21482778, 22232519, 22579287, 23273428, 23374349, 23436906, 23636329, 24135280, 28988771, 31980649, 35512704, 38572507
GO:0043066	Process	Negative regulation of apoptotic process	IBA
GO:0043066	Process	Negative regulation of apoptotic process	IMP	18070883
GO:0043235	Component	Receptor complex	IBA
GO:0043235	Component	Receptor complex	IDA	23382219
GO:0043235	Component	Receptor complex	IEA
GO:0043410	Process	Positive regulation of MAPK cascade	IBA
GO:0043410	Process	Positive regulation of MAPK cascade	IDA	24854121
GO:0043491	Process	Phosphatidylinositol 3-kinase/protein kinase B signal transduction	IMP	18483258
GO:0045121	Component	Membrane raft	IDA	12009895
GO:0045121	Component	Membrane raft	ISS
GO:0045296	Function	Cadherin binding	HDA	25468996
GO:0045739	Process	Positive regulation of DNA repair	IDA	17115032
GO:0045740	Process	Positive regulation of DNA replication	IDA	17115032
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IDA	20551055
GO:0046718	Process	Symbiont entry into host cell	IEA
GO:0048146	Process	Positive regulation of fibroblast proliferation	IEA
GO:0048408	Function	Epidermal growth factor binding	IBA
GO:0048408	Function	Epidermal growth factor binding	IEA
GO:0048471	Component	Perinuclear region of cytoplasm	IEA
GO:0048471	Component	Perinuclear region of cytoplasm	IMP	24854121
GO:0048546	Process	Digestive tract morphogenesis	IEA
GO:0050673	Process	Epithelial cell proliferation	IEA
GO:0050679	Process	Positive regulation of epithelial cell proliferation	IBA
GO:0050679	Process	Positive regulation of epithelial cell proliferation	IDA	10572067
GO:0050679	Process	Positive regulation of epithelial cell proliferation	IEA
GO:0050679	Process	Positive regulation of epithelial cell proliferation	IEA
GO:0050730	Process	Regulation of peptidyl-tyrosine phosphorylation	IMP	12435727
GO:0051015	Function	Actin filament binding	IDA	14702346
GO:0051117	Function	ATPase binding	ISS
GO:0051205	Process	Protein insertion into membrane	TAS	12435727
GO:0051897	Process	Positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	IMP	17655843
GO:0060571	Process	Morphogenesis of an epithelial fold	IEA
GO:0061029	Process	Eyelid development in camera-type eye	IEA
GO:0070141	Process	Response to UV-A	IDA	18483258
GO:0070374	Process	Positive regulation of ERK1 and ERK2 cascade	IDA	20551055
GO:0070374	Process	Positive regulation of ERK1 and ERK2 cascade	IEA
GO:0070374	Process	Positive regulation of ERK1 and ERK2 cascade	IMP	21673316
GO:0070435	Component	Shc-EGFR complex	ISS
GO:0071230	Process	Cellular response to amino acid stimulus	IEA
GO:0071363	Process	Cellular response to growth factor stimulus	IEA
GO:0071364	Process	Cellular response to epidermal growth factor stimulus	ISS
GO:0071392	Process	Cellular response to estradiol stimulus	IDA	20551055
GO:0090037	Process	Positive regulation of protein kinase C signaling	IDA	22732145
GO:0090263	Process	Positive regulation of canonical Wnt signaling pathway	IMP	20302655
GO:0097489	Component	Multivesicular body, internal vesicle lumen	IDA	17714434
GO:0097708	Component	Intracellular vesicle	IDA	11331309
GO:0098609	Process	Cell-cell adhesion	IMP	12435727
GO:1900087	Process	Positive regulation of G1/S transition of mitotic cell cycle	IMP	18483258
GO:1902895	Process	Positive regulation of miRNA transcription	IMP	21673316
GO:1903078	Process	Positive regulation of protein localization to plasma membrane	IDA	22732145
GO:1905208	Process	Negative regulation of cardiocyte differentiation	IMP	23069713

MIM	HGNC	e!Ensembl
131550	3236	ENSG00000146648

Protein

UniProt ID

P00533

Protein name

Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)

Protein function

Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:10805725, PubMed:27153536, PubMed:2790960, PubMed:35538033). Known lig

PDB

1IVO , 1M14 , 1M17 , 1MOX , 1NQL , 1XKK , 1YY9 , 1Z9I , 2EB2 , 2EB3 , 2GS2 , 2GS6 , 2GS7 , 2ITN , 2ITO , 2ITP , 2ITQ , 2ITT , 2ITU , 2ITV , 2ITW , 2ITX , 2ITY , 2ITZ , 2J5E , 2J5F , 2J6M , 2JIT , 2JIU , 2JIV , 2KS1 , 2M0B , 2M20 , 2N5S , 2RF9 , 2RFD , 2RFE , 2RGP , 3B2U , 3B2V , 3BEL , 3BUO , 3C09 , 3G5V , 3G5Y , 3GOP , 3GT8 , 3IKA , 3LZB , 3NJP , 3OB2

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01030	Recep_L_domain	57 → 168	Receptor L domain	Repeat
PF00757	Furin-like	177 → 338	Furin-like cysteine rich region	Domain
PF01030	Recep_L_domain	361 → 481	Receptor L domain	Repeat
PF14843	GF_recep_IV	505 → 637	Growth factor receptor domain IV	Domain
PF07714	PK_Tyr_Ser-Thr	712 → 968	Protein tyrosine and serine/threonine kinase	Domain

Tissue specificity

TISSUE SPECIFICITY: Ubiquitously expressed. Isoform 2 is also expressed in ovarian cancers. {ECO:0000269|PubMed:17671655}.

Sequence

MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEV
VLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALA
VLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDF
QNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGC
TGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYV
VTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFK
NCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAF
ENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKL
FGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCN
LLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVM
GENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVV
ALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGS
GAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGI
CLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAA
RNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSY
GVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPK
FRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQ
QGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTED
SIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLN
TVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRV
APQSSEFIGA

Sequence length

1210

Interactions

View interactions

Show/Hide Causal Diseases (4)

Disease merge term	Disease name	dbSNP ID	References
Causal Diseases caused by PATHOGENIC or LIKELY PATHOGENIC variants from ClinVar only
lung adenocarcinoma	Lung adenocarcinoma	rs397517127, rs727504233, rs1554350382	N/A
Lung carcinoma	non-small cell lung carcinoma	rs121913428, rs397517116, rs1554350366, rs397517094, rs397517127, rs397517098, rs397517106, rs121913465, rs397517108, rs1584238193, rs397517111, rs397517112, rs397517086, rs397517114	N/A
neoplasm	Neoplasm	rs121913428, rs121913465	N/A
Cowden Syndrome	Cowden syndrome 1	rs886037891	N/A

Show/Hide Unknown Diseases (10)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Breast Cancer	Breast cancer	N/A	N/A	GWAS
Carcinoma Of The Head And Neck	squamous cell carcinoma of the head and neck	N/A	N/A	ClinVar
cerebral arteriovenous malformation	Cerebral arteriovenous malformation	N/A	N/A	ClinVar
Cholangiocarcinoma	cholangiocarcinoma	N/A	N/A	ClinVar
Endometrial carcinoma	endometrial carcinoma	N/A	N/A	ClinVar
Glioblastoma	Glioblastoma, Glioblastoma multiforme, somatic	N/A	N/A	GWAS, ClinVar
Glioma	Glioma	N/A	N/A	GWAS
hereditary cancer	Hereditary cancer	N/A	N/A	ClinVar
lung cancer	Lung cancer	N/A	N/A	ClinVar
ovarian cancer	Ovarian cancer	N/A	N/A	ClinVar

Show/Hide Text Mining Associations (875)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
3 Methylglutaconic Aciduria Type I	Associate	19686285
Achalasia Addisonianism Alacrimia syndrome	Associate	22431556
Acidemia isovaleric	Associate	33533191
Acne Vulgaris	Associate	34025636
Acquired ichthyosis	Associate	24691054, 36303457
Acquired Immunodeficiency Syndrome	Associate	21083371
Acrocephalosyndactylia	Associate	33592873
Acrospiroma	Associate	19252473
ACTH Secreting Pituitary Adenoma	Associate	35563252
Acute Coronary Syndrome	Associate	18664296
Acute Kidney Injury	Associate	33436543
Acute Lung Injury	Associate	36344490
Adenocarcinoma	Associate	10037277, 12377812, 1419612, 1457340, 15329413, 15956035, 16014883, 16052218, 16189154, 16521222, 16533793, 16552419, 16598760, 16731604, 16825506 View all (352 more)
Adenocarcinoma	Stimulate	26230859, 27322143, 28220630, 34234879, 36845145
Adenocarcinoma Bronchiolo Alveolar	Associate	16189154, 17409999, 17410000, 17591931, 17618248, 18161663, 18448997, 18978572, 19179908, 19844187, 20512074, 21422434, 22237264, 23287850, 25684509 View all (4 more)
Adenocarcinoma Follicular	Associate	1699752, 26617848
Adenocarcinoma in Situ	Associate	17618248, 23242438, 30797486, 31446140, 33706781, 36325966, 36578104, 37004157
Adenocarcinoma Mucinous	Associate	19479974, 21057220, 22732796, 24002608, 25813151, 26992209, 28940943, 29698701, 30298562, 30648815, 32747123
Adenocarcinoma Mucinous	Inhibit	25550848
Adenocarcinoma Of Esophagus	Associate	16521222
Adenocarcinoma of Lung	Associate	15696205, 15737014, 15851406, 15920544, 16049312, 16052218, 16189154, 16219624, 16533793, 16552419, 16619582, 16931592, 17045698, 17096850, 17189989 View all (905 more)
Adenocarcinoma of Lung	Inhibit	23709419, 28436422
Adenocarcinoma Papillary	Associate	23242438, 25550848, 28383802, 29090842
Adenoma	Associate	10686540, 21102417, 24287797, 25675982, 26037168, 26617848, 29149105, 34941983, 35260162, 35563252, 37482844
Adenoma	Stimulate	15098012
Adenoma Islet Cell	Inhibit	25277177
Adenoma Oxyphilic	Associate	22161775
Adenoma Pleomorphic	Associate	16552419, 20107421, 21626008, 26682906, 29675860, 35743969, 36115683, 36243681, 37614204
Adenomatous Polyposis Coli	Associate	26198262, 7793821
Adrenal Cortex Neoplasms	Associate	23139256, 23725124
Adrenocortical Adenoma	Associate	24457059
Adrenocortical Carcinoma	Associate	20693985, 24457059, 25078331, 35462410
Aicardi Syndrome	Associate	20824717
AIDS Arteritis Central Nervous System	Associate	35862191
Airway Obstruction	Associate	24126395
Albinism Oculocutaneous	Associate	19826477
Allan Herndon Dudley syndrome	Associate	36429891
Allergic Fungal Sinusitis	Associate	28398769
Alopecia	Associate	24691054
Alveolar Bone Loss	Associate	33917440
Alzheimer Disease	Associate	22801742, 24628925, 30026459, 31989994, 35715361, 37010714, 37819172, 39273172
Ameloblastoma	Associate	22300665, 24374844, 25099616, 25991665, 35484883
Amyloid Neuropathies	Associate	35715361
Amyotrophic Lateral Sclerosis	Associate	37682161
Anal Canal Carcinoma	Associate	20459770
Androgen Insensitivity Syndrome	Associate	28859123, 35641658
Anemia	Associate	35659581, 36253772
Aneuploidy	Associate	17643093, 21102417, 2372483, 24344012, 29335443, 34303217
Aneuploidy	Stimulate	20082448
Aneurysm	Associate	29165337
Angina Stable	Associate	19204206, 23559153, 29328373, 29516969, 35645132, 37723846
Anodontia	Associate	20579378, 28911955
Anophthalmia with pulmonary hypoplasia	Associate	22761868
Anorexia	Associate	34577852
Anus Neoplasms	Associate	24021343, 28126304, 29624161, 29700411
Apical Hypertrophic Cardiomyopathy	Stimulate	35674115
Apparent mineralocorticoid excess	Associate	32355271
Arsenic Poisoning	Associate	31864032
Arteriosclerosis	Associate	19840952
Arthritis	Associate	24385683
Arthritis Experimental	Associate	21107284
Arthritis Psoriatic	Associate	8980296
Arthritis Rheumatoid	Associate	17082220, 28173856, 28700691, 30091955, 32840301, 34918712
Ascites	Associate	22430797
Asthma	Associate	15502346, 15929951, 30478434, 35473352, 38375886
Asthma	Stimulate	15860714
Astrocytoma	Associate	10987838, 12569609, 1503912, 16133418, 17327574, 18507036, 18949739, 19127042, 19224764, 19603027, 19767728, 20639215, 21455841, 23595626, 23737970 View all (7 more)
Ataxia	Associate	36082650
Ataxia Telangiectasia	Associate	29849821
Atelosteogenesis type 2	Associate	34116229
Atherosclerosis	Associate	18664296, 34020127
Atresia of small intestine	Associate	26892442
Atrial Fibrillation	Associate	34938350
Atrophy	Associate	23107432
Atypical Squamous Cells of the Cervix	Associate	32367600
Autism Spectrum Disorder	Associate	27571009, 37108604
Azoospermia	Associate	36969237
Back Pain	Associate	24195468, 35365042
Bacterial Infections	Associate	17220369, 40275124
Barrett Esophagus	Associate	16521222, 16857803, 23273065, 25740071, 29991802, 35437997, 36604181
Basal cell carcinoma infundibulocystic	Stimulate	30864368
Basal Cell Carcinoma Nonsyndromic	Associate	25605142
Basaloid Follicular Hamartoma Syndrome Generalized Autosomal Dominant	Associate	26060045
Behcet Syndrome	Associate	23625463
Beta ketothiolase deficiency	Associate	32790013
Bicuspid Aortic Valve Disease	Associate	29165337
Bile Duct Neoplasms	Associate	36317517
Biliary Atresia	Associate	16739351
Biliary Tract Neoplasms	Associate	19201881, 19777609, 21087480, 22210086, 25217982, 32323774
Bipolar Disorder	Associate	18317468
Blood Coagulation Disorders	Associate	36174772
Bohring syndrome	Associate	28388586
Bone Diseases	Associate	19648884, 32747123, 39245880
Bone Diseases	Stimulate	29858031
Brain Diseases	Associate	24197981, 26469914, 31944608, 35088537, 35365042, 35857126, 36534728, 36596729, 40075375
Brain Injuries Traumatic	Associate	22543850
Brain Neoplasms	Associate	16097449, 1671751, 17867825, 19622585, 20031968, 20595147, 20604919, 20627894, 20730556, 22429330, 23129122, 23134665, 23180004, 24419416, 24679729 View all (71 more)
Brain Neoplasms	Inhibit	29110584
Brain Neoplasms	Stimulate	31882734
Breast Neoplasms	Associate	10903426, 10908152, 11087732, 11238942, 11484962, 11500850, 11692142, 11751923, 11796827, 11825114, 11859072, 11863114, 12031094, 12037031, 12134064 View all (415 more)
Breast Neoplasms	Inhibit	19307053, 25150698, 25826086, 38189813
Breast Neoplasms	Stimulate	19771133, 20385028, 21761335, 23082819, 24124521, 28629477, 30736768, 33340635, 9708917
Breast Neoplasms Male	Associate	19442295, 1949915, 22527098, 23308200, 27765917
Bronchial Diseases	Associate	12762344
Bronchiolitis Obliterans Syndrome	Associate	31665560
Bronchitis	Associate	23551418
Bronchitis Chronic	Associate	14988406
CADASIL	Associate	35641310, 35862191
Calcinosis	Associate	16900093
Calcinosis Cutis	Associate	15220376, 15335267, 15865067, 15920550, 17649779, 18822183, 19702827, 19935791, 23226389, 24285021, 24609222, 25781862, 26850068, 26892442, 27639677 View all (16 more)
Calcinosis Cutis	Inhibit	24653752, 30837448
Calcinosis Cutis	Stimulate	30833579
Cap Myopathy	Associate	18386291, 2478180
Carcinogenesis	Associate	10473632, 10686540, 11351043, 14520458, 15140260, 15365565, 1557402, 15867774, 16112910, 16505275, 16521222, 16619503, 16965395, 17533150, 17909029 View all (92 more)
Carcinogenesis	Stimulate	20424164
Carcinoid Tumor	Associate	15502346, 15920550, 16424381, 16612146, 23139256
Carcinoma	Associate	11786405, 11920518, 15305194, 17663798, 17671194, 17823122, 19224764, 20820870, 22523351, 23917679, 25563452, 26125777, 31776927, 33373269, 7977648, 8538164 View all (1 more)
Carcinoma Acinar Cell	Associate	32727606
Carcinoma Adenoid Cystic	Associate	18542074, 20824717, 21047402, 21320355, 23496982, 23942070, 27461660, 29109770, 29954240, 33172898
Carcinoma Adenoid Cystic	Stimulate	25997612
Carcinoma Adenosquamous	Associate	17186532, 17238183, 19563658, 22228640, 22896669, 22996376, 23037472, 23769878, 24351833, 26068980, 26923333, 27623437, 31221183, 32151507, 32367600 View all (7 more)
Carcinoma Adenosquamous	Stimulate	19270646
Carcinoma Basal Cell	Stimulate	18559090, 36737799
Carcinoma Basal Cell	Associate	18752048, 19434314, 23762360, 23873690, 25605142, 27285994, 28120452, 28388586, 30173251, 32382535, 35564692
Carcinoma Bronchogenic	Associate	25926253
Carcinoma Ductal	Associate	15649255, 16311351
Carcinoma Ductal Breast	Associate	15649255, 29937187
Carcinoma Embryonal	Associate	12783324, 16729016, 18660793
Carcinoma Endometrioid	Associate	19604315, 32994315
Carcinoma Hepatocellular	Associate	11355950, 16936701, 16937526, 17150109, 17583545, 17623837, 19145479, 19835603, 20856226, 21245850, 22210086, 22860012, 23220047, 23285165, 23785399 View all (60 more)
Carcinoma Hepatocellular	Inhibit	24886097, 31465839
Carcinoma Hepatocellular	Stimulate	34592904
Carcinoma in Situ	Associate	12762344, 16158937, 23927961
Carcinoma Intraductal Noninfiltrating	Associate	16528377, 22315424, 28634007, 30962452
Carcinoma Large Cell	Associate	16552419, 17238183, 21272159, 22836289, 23196793, 23518631, 23738762, 24351833, 25700797, 26430808, 26486077, 28768973, 30978501
Carcinoma Lobular	Associate	8254086
Carcinoma Merkel Cell	Associate	18408656, 28359267
Carcinoma Mucoepidermoid	Associate	23361279, 23933559, 24351833, 26575266, 33581505
Carcinoma Neuroendocrine	Associate	25700797, 28538405, 28768973, 30550363, 32762742, 35016432, 38591867
Carcinoma Non Small Cell Lung	Associate	10190311, 10761709, 14679115, 14679116, 14704124, 15015570, 15118073, 15365565, 15378500, 15611511, 15712203, 15728811, 15802268, 15851406, 15897464 View all (2428 more)
Carcinoma Non Small Cell Lung	Stimulate	16705311
Carcinoma Non Small Cell Lung	Inhibit	17409827, 19884854, 27457475, 30034220, 30049184, 30285266, 30704458, 33546082, 36705363, 36997606, 37187027, 37291860, 37907645, 37984347, 38054663
Carcinoma Ovarian Epithelial	Associate	11328410, 15571614, 17330838, 18182111, 18559505, 18628764, 24816687, 25520097, 26261554, 28009971, 28646172, 29996940, 31001917, 32660222, 36580004, 38250760 View all (1 more)
Carcinoma Pancreatic Ductal	Associate	16497872, 17726239, 18254976, 18505086, 20430737, 22045191, 22086503, 24048788, 25121413, 25679210, 26251290, 27187683, 27259358, 27391842, 28352075 View all (4 more)
Carcinoma Pancreatic Ductal	Stimulate	20473902, 26339400
Carcinoma Papillary	Associate	1699752, 23529321, 23917679, 26718882
Carcinoma Papillary	Stimulate	22161775
Carcinoma Renal Cell	Associate	11328410, 11720477, 12944410, 14520458, 15220376, 15956968, 16052341, 16158924, 17465216, 18928570, 19747398, 19884559, 21949687, 22025615, 22161775 View all (34 more)
Carcinoma Renal Cell	Stimulate	14520461
Carcinoma Small Cell	Associate	24422746, 24828667, 24986561, 26424310, 27488410, 28193529, 28723866, 28838401, 29317428, 30217489, 31063862, 31959344, 32179180, 35793695
Carcinoma Squamous Cell	Associate	11275796, 14708611, 14739904, 1503897, 15205458, 15365562, 15466396, 15692721, 15865067, 15920558, 16547470, 16582597, 16648870, 17186532, 17238183 View all (149 more)
Carcinoma Squamous Cell	Stimulate	21598042, 21819702, 7507302, 8679464
Carcinoma Squamous Cell	Inhibit	30837448
Carcinoma Transitional Cell	Associate	1712624, 1713019
Carcinoma Transitional Cell	Stimulate	30296252
Carcinosarcoma	Associate	14611676, 37530323, 37837329
Cardiomegaly	Associate	36046382
Cardiomyopathy Dilated 1l	Associate	36005198
Cardiomyopathy Dilated 1l	Inhibit	36005198
Cardiovascular Diseases	Associate	36146910, 37543587
Cartilage Diseases	Associate	24385683
Celiac Disease	Associate	21364874, 23966426, 24204586, 36611909
Cell Transformation Neoplastic	Associate	11087732
Cell Transformation Viral	Associate	39353908
Cementoma	Associate	20956971
Central Nervous System Diseases	Associate	19692934, 22733536, 24105277, 28376735, 33112047
Central Nervous System Infections	Associate	37678673
Central Nervous System Neoplasms	Associate	26681766
Cerebral Infarction	Associate	35140708, 35862191
Cerebral Small Vessel Diseases	Associate	35862191
Cerebrospinal Fluid Rhinorrhea	Associate	33122107
Cerulean cataract	Stimulate	11494118
Cerulean cataract	Associate	16648870, 8644846
Cheilitis glandularis	Stimulate	28285559
Chemical and Drug Induced Liver Injury	Associate	17106442, 29110841, 30139222
Chest Pain	Associate	24691054, 35343187
Cholangiocarcinoma	Associate	15855163, 16032426, 16846514, 18087285, 19414361, 20565817, 21472131, 21492330, 21673683, 22591401, 23139256, 23704979, 24186137, 24550739, 25815516 View all (13 more)
Cholelithiasis	Associate	17148666
Cholelithiasis	Inhibit	18285671
Cholesteatoma	Associate	14620675, 24311896
Cholesteatoma Middle Ear	Associate	14620675
Chondrosarcoma	Stimulate	24748236
Chondrosarcoma	Associate	26214645
Chordoma	Associate	20164240, 20670138, 23559153, 24621885, 28272674, 28753113, 30322893, 34550531, 35896603, 37024492
Choreoathetosis Hypothyroidism And Neonatal Respiratory Distress	Associate	29037198
Choriocarcinoma	Associate	12124830
Choriocarcinoma	Stimulate	20608935
Choroidal Effusions	Associate	35347923
Choroiditis	Associate	21738104
Chromosome 1q21.1 Deletion Syndrome 1.35 Mb	Associate	24986561
Chromosome 7 monosomy	Associate	21252859, 25611230
Chromosome Aberrations	Associate	17643093, 27578512
Chromosome Deletion	Associate	36622089
Cleft Lip	Associate	30411541
Cleft Palate	Associate	30411541
Cockayne Syndrome	Associate	24743307
Colitis Associated Neoplasms	Associate	39370253
Colitis Ulcerative	Associate	23825635, 33299870, 37960728, 39252247
Colonic Neoplasms	Associate	10686540, 12824187, 14742435, 16886596, 17264401, 18032824, 18700047, 19233916, 19584170, 19795022, 19997103, 23572025, 2365825, 24894453, 25987127 View all (7 more)
Colorectal Neoplasms	Associate	10362109, 12748850, 1419612, 14684586, 14742435, 14966913, 15010475, 15075253, 15143334, 15304500, 15832190, 15888451, 15908435, 15923435, 15980160 View all (469 more)
Colorectal Neoplasms	Stimulate	15598946, 17109495
Colorectal Neoplasms	Inhibit	20007841, 23173730, 24788807, 25568935, 25823645, 28432610, 28446505, 28593995, 28797274, 29703606, 35915157, 36779536, 36921693, 37628934
Colorectal Neoplasms Hereditary Nonpolyposis	Associate	35638907
Coma	Associate	34766562
Compassion Fatigue	Associate	25135958
Complement Component 7 Deficiency	Associate	24922009, 32384877
Congenital disorder of glycosylation type 1B	Associate	30559455, 32093629
Conjunctival Diseases	Associate	32833992
Conjunctival Neoplasms	Associate	20498858
Corneal Neovascularization	Associate	34587359, 35608132
Coronary Artery Disease	Stimulate	12869389
Coronary Artery Disease	Associate	29328373
Coronary Artery Disease	Inhibit	31886261
Coronary Disease	Associate	33849106
Corticobasal Degeneration	Associate	28271184
Cough	Associate	31779047
COVID 19	Associate	32497778, 32691695, 32805728, 34020127, 34045585, 34322810, 34931923, 35855804, 35938548, 36174772, 37936693
COVID 19	Stimulate	34135558, 35816430
Craniopharyngioma	Associate	25990246
Crazy paving pattern	Associate	17409892, 25361983, 31710020, 36029220
Cryptococcosis	Associate	36450693
Cryptogenic Organizing Pneumonia	Stimulate	23841084
Cystic Fibrosis	Associate	16928707, 18757521, 21193404, 29351448, 35412656
Cystic Fibrosis	Stimulate	32927759
Cysts	Associate	18587325
Cytokine Release Syndrome	Associate	23566546
Cytokine Release Syndrome	Stimulate	35491845
Deafness Autosomal Recessive 53	Stimulate	33925065
Death	Inhibit	15378500, 18453539
Death	Associate	17351259, 23154553, 24064329, 24285021, 25679210, 27160084, 27294665, 28446533, 32912174, 33831609, 34436667, 34706519, 34740925, 35292755, 36188649
Death	Stimulate	23775802
Degloving Injuries	Associate	26988277
Dementia	Associate	35327643, 37920971
Dental Caries	Associate	30352571
Dentigerous Cyst	Associate	23207846
Depressive Disorder	Inhibit	21807767
Depressive Disorder	Associate	31022775, 35870967, 37340599
Depressive Disorder Major	Inhibit	21807767
Dermatitis	Associate	27206134
Dermatitis Atopic	Associate	33289509
Dermatitis Contact	Associate	20981109
Dermatofibrosarcoma	Associate	22523339, 32956651
Desmoid disease hereditary	Associate	19242968
Developmental Disabilities	Associate	18505685
Diabetes Gestational	Associate	20144210, 26302821, 33890634
Diabetes Mellitus	Stimulate	27411924
Diabetes Mellitus	Inhibit	37182870
Diabetes Mellitus Type 1	Associate	33827531, 35650387, 36303457
Diabetes Mellitus Type 2	Associate	33212505, 34402100, 35222283
Diabetic Nephropathies	Associate	37789280
Diabetic Retinopathy	Associate	25997411, 40214234
Diarrhea	Associate	16052341, 17410005, 18309947, 20159991, 20621735, 26988277, 30512189, 32634610, 34577852, 35291829, 35343187, 35659581, 35798241, 36729110, 36813747 View all (4 more)
Diarrhea	Stimulate	38171775
Diarrhea 5 With Tufting Enteropathy Congenital	Associate	24201754
Diffuse Intrinsic Pontine Glioma	Associate	24076776, 33539525
Disease	Stimulate	17888028
Disease	Associate	19204206, 21157973, 23059777, 23407558, 24039221, 26790969, 27061536, 28843359, 29110716, 29516969, 32229189, 32581041, 33247670, 35201951, 35611637, 37096765, 37221352, 37914594, 9062361 View all (4 more)
Disease	Inhibit	30120912
Disease Progression	Stimulate	19850643
Disease Progression	Associate	23059777, 26262682, 26577492, 26790969, 27145431, 29516969, 30444875, 30927306, 32162810, 33203645, 37096765
Disease Progression	Inhibit	27381430, 35614407
Disorders of Sex Development	Associate	27255162
Disseminated Intravascular Coagulation	Associate	28730909
Dizziness	Associate	30851728, 32393286
DNA Virus Infections	Associate	31875360, 8128479
Donohue Syndrome	Associate	2808704
Doyne honeycomb retinal dystrophy	Associate	33909993
Drug Eruptions	Associate	25219648
Drug Hypersensitivity	Associate	20040267, 26186355
Drug Related Side Effects and Adverse Reactions	Associate	1512230, 19305165, 20159991, 20961434, 21740526, 22117530, 22389159, 22486600, 22986230, 22990204, 23036052, 23200832, 23213241, 2420787, 25227813 View all (18 more)
Drug Related Side Effects and Adverse Reactions	Inhibit	19305165, 25247711, 25383627, 27467256, 32577785, 35470756
Drug Related Side Effects and Adverse Reactions	Stimulate	34123574, 34290709
Drug Resistant Epilepsy	Associate	20925915
Duodenal Neoplasms	Associate	28794362
Duodenal Ulcer	Associate	9176072
Dyskinesias	Associate	19623652
Dysplastic Nevus Syndrome	Associate	20332305, 29966661, 31421471, 34402100, 36604181, 37817274
Dysplastic Nevus Syndrome	Stimulate	33274363
Dyspnea	Associate	29178024, 30817606, 35343086, 35343187, 36905787
Ectodermal Dysplasia	Associate	35563746
Edema	Associate	27578512
Embolism	Associate	27261103, 34107910
Emphysema	Associate	35081265
Endocarditis Non Infective	Associate	33752413, 37143409
Endocrine Gland Neoplasms	Associate	31182586
Endocrine System Diseases	Associate	22854050, 23039365, 37460683, 38160230
Endodermal Sinus Tumor	Associate	12783324
Endodermal Sinus Tumor	Stimulate	20608935
Endometrial Hyperplasia	Associate	17618248, 18448997, 19179908, 19844187, 20512074, 30121391, 32599981
Endometrial Neoplasms	Associate	15280405, 16140938, 1687493, 16905765, 18334972, 19088718, 19604315, 19917135, 20218740, 20564127, 20579378, 20664599, 22393970, 22540299, 22885469 View all (5 more)
Endometriosis	Associate	15749523, 25658832, 28187748, 31027056, 32762950, 9086334
Enhanced S Cone Syndrome	Associate	37770427
Enteritis	Associate	28953659, 35901658
Enterocolitis Necrotizing	Inhibit	22675459
Eosinophilic Esophagitis	Associate	35437997, 35839075
Ependymoma	Associate	20713864, 33085768
Epidermolysis Bullosa Dystrophica	Associate	31796084
Epidermolysis Bullosa Simplex	Associate	34643242
Epidermolysis bullosa with pyloric atresia	Inhibit	27164304
Erectile Dysfunction	Associate	30333254
Esophageal Achalasia	Associate	20163722
Esophageal and Gastric Varices	Associate	36264285
Esophageal Neoplasms	Inhibit	10037277
Esophageal Neoplasms	Associate	10908564, 16357520, 16425431, 16857803, 19136271, 20620594, 22555809, 23874846, 2420787, 25550802, 26681028, 27420968, 28777832, 29516969, 32068233 View all (8 more)
Esophageal Squamous Cell Carcinoma	Associate	17622245, 18405350, 20036807, 20534479, 22389159, 22450065, 22845557, 22870241, 23207070, 23232108, 23244191, 23274581, 23426935, 23874846, 24052437 View all (36 more)
Esophageal Squamous Cell Carcinoma	Stimulate	24131756
Esophageal Stenosis	Associate	34263613
Esophagitis	Associate	22870241, 35564692
Esthesioneuroblastoma Olfactory	Associate	29324814
Exanthema	Associate	16052341, 17409827, 20621735, 20961434, 22271877, 24691054, 30512189, 30540703, 30557370, 33153894, 34577852, 34953403, 35291829, 35659581, 35696748, 36813747, 38064607, 39739938 View all (3 more)
Exanthema	Stimulate	32788540, 33087401
Eyelid Neoplasms	Associate	28174788
Familial cylindromatosis	Associate	29884612
Familial paroxysmal dystonia	Associate	25180832
Farber Lipogranulomatosis	Associate	27046167
Fatigue	Associate	23980091, 28758857, 36905787, 38064607
Femoral Fractures Distal	Associate	26045851
Fetal Macrosomia	Associate	26302821
Fever	Inhibit	26654941
Fever of Unknown Origin	Associate	37922692
Fibrolamellar hepatocellular carcinoma	Associate	22872444, 28486549
Fibrosarcoma	Associate	35032896, 39577666
Fibrosis	Associate	15780084, 19535569, 23597419, 26064952, 28336963, 29247171, 34070150, 35176481, 35850069, 36174772, 37418274
Fibrosis	Stimulate	23841084
Fibrous Dysplasia Polyostotic	Associate	35348294
Focal cortical dysplasia of Taylor	Associate	30568293
Focal Nodular Hyperplasia	Stimulate	28947799
Focal Nodular Hyperplasia	Associate	32058355
Folate Malabsorption Hereditary	Associate	34445544
Folliculitis	Associate	30557370
Fractures Spontaneous	Associate	29849818
Gallbladder Neoplasms	Associate	18825277, 20961434, 25004291, 26320430, 27461681, 27644637, 29352306, 34171432, 34798839, 35196196, 38092180
Gallstones	Stimulate	17148666
Gallstones	Inhibit	18285671
Gallstones	Associate	26320430
Gardner Syndrome	Associate	26755002
Gastritis	Inhibit	12641822
Gastritis	Associate	34471638
Gastritis Atrophic	Inhibit	12641822
Gastro enteropancreatic neuroendocrine tumor	Associate	26684240
Gastroesophageal Reflux	Associate	27387915, 36092955
Gastrointestinal Diseases	Stimulate	17330838
Gastrointestinal Diseases	Associate	39739938
Gastrointestinal Neoplasms	Associate	16857803, 19331154, 24960403, 26059438
Gastrointestinal Stromal Tumors	Associate	17359542, 17643098, 19298600, 22654456, 25557174
Genetic Diseases Inborn	Associate	24346091
Gestational Trophoblastic Disease	Associate	9119881
Glaucoma Open Angle	Associate	29452408
Glioblastoma	Associate	10576656, 10645226, 10653004, 10764044, 11087732, 11092616, 11302335, 11302336, 11302337, 11351043, 11511795, 11550311, 11916499, 12754350, 14701753 View all (342 more)
Glioblastoma	Stimulate	15090567, 22794670, 27797218, 33892666
Glioblastoma	Inhibit	25277177, 25787115
Glioma	Associate	10595738, 11092616, 11770895, 15184909, 15197348, 15279711, 1557402, 1563013, 15701286, 16112910, 16212813, 16645215, 1693434, 17189383, 17226962 View all (140 more)
Glioma	Inhibit	33892666
Glioma of Brain Familial	Associate	21455841
Gliosarcoma	Associate	26045851, 26443480, 31073965, 34504233, 35381788
Gliosis	Inhibit	21468591
Glomerulonephritis IGA	Associate	32791747
Glomerulonephritis IGA	Stimulate	40214391
Glomerulonephritis Membranous	Inhibit	32094923
Glucosephosphate Dehydrogenase Deficiency	Associate	26366417
Glycogen Storage Disease IIIA	Associate	39732365
Glycogen Storage Disease IIIB	Associate	26047516, 30045314, 30253083, 33183013, 34116229, 35739536
Glycogen Storage Disease Type IV	Associate	25851627, 28538405, 35477147
Graft vs Host Disease	Associate	30425334
Granulosa cell tumor of the ovary	Associate	12796025
Graves Ophthalmopathy	Associate	40299971
Growth Factors Combined Defect of	Associate	33260345
Guillain Barre Syndrome	Associate	34763483
Hamartoma Syndrome Multiple	Associate	27900366, 28320414
Hamman Rich Syndrome	Associate	28446533
Hand Foot Syndrome	Associate	37723837
Head and Neck Neoplasms	Associate	10206306, 11920518, 11986789, 12915878, 15205458, 15829495, 16510606, 17189989, 17431120, 18316548, 18507008, 18832597, 19074873, 19568408, 20237991 View all (51 more)
Head and Neck Neoplasms	Stimulate	11875748, 39369912
Head and Neck Neoplasms	Inhibit	25563452
Headache	Associate	34766562, 37463768
Hearing Loss Noise Induced	Associate	33242228
Heart Arrest	Associate	35343187
Heart Diseases	Associate	22732799, 24691054, 31315351, 34402100
Heart Failure	Associate	23975515, 31419239, 37092838
Helicobacter Infections	Associate	12641822
Helicobacter Infections	Stimulate	9176072
Hemangioblastoma	Associate	20730556, 26768750, 7639324
Hematologic Neoplasms	Associate	11843246
Hematuria Benign Familial	Stimulate	12915878
Hemoptysis	Associate	35343086
Hemorrhage	Associate	20708924, 22294255
Hepatitis B	Associate	16936701, 19434314, 27472239
Hepatitis B	Stimulate	19442295
Hepatitis C	Associate	27137988, 28507206, 30782931
Hepatitis E	Associate	26369702
Hepatoblastoma	Associate	27910913
Hereditary Angioedema Type III	Inhibit	19423651
Hereditary Breast and Ovarian Cancer Syndrome	Associate	15480434, 16238103, 17164758, 17369752, 17598908, 17663798, 18505086, 18698037, 21574647, 22523339, 26580964, 27488410, 28775148, 28947780, 30139236, 30394935, 35290621, 36916425 View all (3 more)
Hereditary Breast and Ovarian Cancer Syndrome	Stimulate	35865143
Hereditary leiomyomatosis and renal cell cancer	Associate	1936340
Heredodegenerative Disorders Nervous System	Associate	36183486
Herpes Zoster	Associate	34322810
Histiocytoma Malignant Fibrous	Associate	15154665, 15254554, 15274392, 19940402
HIV Infections	Associate	20498858, 34714196
Huntington Disease	Associate	22974559
Hydatidiform Mole	Associate	11737472, 22684234
Hydrothorax	Associate	25635424, 35365042
Hyperandrogenism	Associate	32289280
Hyperglycemia	Associate	35526510
Hyperimmunoglobulin G1(A1) Syndrome	Associate	26247526
Hyperplasia	Associate	14988406, 21505178, 27709733, 3182322, 36867212, 37340599
Hypersensitivity	Associate	20195171
Hypersensitivity Immediate	Associate	20579378, 30872465, 40157900
Hypersensitivity Immediate	Inhibit	29701925
Hypertension	Associate	33410885, 33635564, 35524294, 36862882
Hypertension Pulmonary	Associate	25925667, 29845760, 35674115
Hypertrophy	Associate	14988406, 24554716
Hypesthesia	Associate	28758857, 31088573
Hypogonadism	Associate	30098700
Hypokalemia	Associate	35659581
Hypopharyngeal Neoplasms	Associate	22452803, 30365065
Hypoxia	Stimulate	17425591, 17670948, 20395290, 20861305, 23185433, 28038470, 28330951, 29123322, 29845760, 30487162, 31776131, 35634326, 35674115, 40244269
Hypoxia	Associate	20942457, 21966417, 22411794, 22420963, 22863020, 23589494, 23636329, 23696831, 23867129, 25860915, 26032726, 26207380, 26467103, 27625398, 27802455 View all (11 more)
Hypoxia Brain	Stimulate	17670948, 20395290, 23185433, 37377902
Hypoxia Brain	Associate	22420963, 23636329, 26849233, 28188223, 28330951, 28801308, 29845760, 29866927, 32823915, 34290709, 35674115
Ichthyosis	Associate	1532884
Idiopathic Noncirrhotic Portal Hypertension	Associate	30864368
Idiopathic Pulmonary Fibrosis	Stimulate	23841084
Idiopathic Pulmonary Fibrosis	Associate	27350261, 30810067, 32426915, 34315881
Idiopathic Pulmonary Fibrosis	Inhibit	27575421
Immune dysfunction with T cell inactivation due to calcium entry defect 1	Associate	36154925
Immune System Diseases	Associate	35241046
Immunoglobulin G4 Related Disease	Associate	33775999
Immunologic Deficiency Syndromes	Associate	35839075
Infections	Associate	18276593, 27223085
Infectious Mononucleosis	Associate	36154925
Infertility	Associate	32289280, 36303457
Inflammation	Associate	15929951, 17148666, 17977827, 18276593, 18664296, 20962773, 22693070, 22952984, 23688423, 24082147, 24268047, 24434780, 24691054, 24978309, 25684939 View all (22 more)
Inflammation	Stimulate	16932740, 32927759
Inflammatory Bowel Diseases	Associate	22301110, 26787018
Inflammatory Breast Neoplasms	Associate	17351259, 17700572, 19902352, 20406946, 20503407, 21360074, 21559822, 23280128, 23647160, 26821068, 28270211, 28426875, 29879283, 30086764, 37048158
Influenza Human	Associate	23731466
Insulin Resistance	Associate	32651353, 36411648
Intervertebral Disc Degeneration	Associate	24173697
Intestinal Diseases	Associate	7819044
Intestinal Neoplasms	Associate	37306349
Intestinal Perforation	Associate	22606320
Intracranial Arterial Diseases	Associate	35201951
Intrahepatic Cholestasis of Pregnancy	Associate	35643225
Keratoconus	Associate	31467338
Keratoderma Palmoplantar	Associate	36116508
Keratosis Actinic	Associate	20156290
Keratosis Seborrheic	Associate	1532884, 20064244, 21078999
Kidney Diseases	Associate	15780084, 26064952, 31419239, 34501555
Kidney Failure Chronic	Associate	23468851, 28537806, 29164298, 31906817
Kidney Neoplasms	Inhibit	17465216
Kidney Neoplasms	Associate	19603096, 20359967, 24652385, 25789858, 30770799, 30941984, 31672701, 32413049, 34399807, 36933996, 39780215
Kininogen Deficiency High Molecular Weight and Low Molecular Weight	Associate	15832192
Laryngeal Neoplasms	Associate	10096253, 23775802, 23867129, 25008564, 25736926, 29938470
Laryngeal Web Familial	Associate	19673037
Lead Poisoning	Associate	34501555
Leigh syndrome French Canadian type	Associate	25692143
Leiomyoma	Associate	15749523, 1936340, 31468104
Leiomyoma of vulva and esophagus	Associate	22252115
Leiomyosarcoma	Associate	15772959, 23334251, 29295562
Leukemia	Associate	26633023
Leukemia Lymphocytic Chronic B Cell	Associate	22479527, 26870997, 28346673
Leukemia Myelogenous Chronic BCR ABL Positive	Associate	21501493, 22511990, 23806289, 27196940
Leukemia Myeloid Accelerated Phase	Associate	23867129
Leukemia Myeloid Acute	Associate	23974111, 26744873, 27488458, 29781401, 32587297, 34193978, 37629110
Leukemia Plasma Cell	Associate	35610009
Leukemia Promyelocytic Acute	Associate	32755558
Leukoencephalopathies	Associate	35862191
Leukoencephalopathies	Stimulate	38054663
Leukopenia	Associate	37557185
Leukoplakia	Associate	23492901, 29516925
Leukoplakia Oral	Associate	23492901, 35488777
Li Fraumeni Syndrome	Associate	24835218, 32179180
Lichen Planus Oral	Associate	24880441
Lichenoid Eruptions	Associate	24880441
Lipoma	Associate	37194849
Liposarcoma Myxoid	Associate	20522586
Liver Diseases	Associate	24186137, 27336603, 29807405, 30139222
Liver Failure	Associate	23114924, 30139222, 34235224
Liver Failure	Stimulate	23867504
Liver Neoplasms	Associate	24886097
Long QT Syndrome	Associate	35798241
Long Qt Syndrome 3 6	Associate	28006816
Lown Ganong Levine Syndrome	Associate	18000506, 18191993, 18701186, 32285618, 33548986, 35607295
Lung Diseases	Associate	20975376, 23787800, 23922022, 25219648, 26823294, 27072258, 27580550, 27625398, 28188223, 28387300, 30109777, 30342483, 30872465, 32367600, 33080701 View all (10 more)
Lung Diseases	Inhibit	30837448
Lung Diseases Interstitial	Stimulate	21791074, 23592411, 23841084, 29327061
Lung Diseases Interstitial	Associate	24819665, 25669832, 27350261, 28221867, 28794368, 29936470, 30192383, 30506897, 31584970, 32374485, 32927121, 32999231, 34807270, 35798241, 36049654, 36890493, 37169657, 37991747 View all (3 more)
Lung Injury	Associate	38228746
Lung Neoplasms	Associate	10471051, 10823420, 12077147, 14739904, 15118073, 15258328, 15329413, 15737014, 15841079, 15870831, 16049312, 16052218, 16329133, 16334162, 16357520 View all (823 more)
Lung Neoplasms	Inhibit	24662823, 24908424, 37187027, 37898846
Lung Neoplasms	Stimulate	25640358, 28974261
Lupus Erythematosus Systemic	Associate	37072752
Lupus Nephritis	Associate	36335193
Lymphangioleiomyomatosis	Associate	36231025
Lymphangitis	Associate	30516345
Lymphatic Metastasis	Associate	10096253, 15712203, 16963112, 17211865, 18316548, 18473353, 19331236, 19487967, 20062009, 20181250, 20430737, 21276138, 21414214, 22086503, 22126484 View all (36 more)
Lymphatic Metastasis	Stimulate	15598946, 18087285, 18505086, 18700025, 22537942, 23220854, 23608326, 24052437, 24131756, 26099724, 27488595, 29665129, 35241559
Lymphatic Metastasis	Inhibit	20096104
Lymphedema Hereditary IB	Associate	36085020
Lymphoblastic Transformation Inhibition of	Inhibit	36117171
Lymphoma	Associate	35806064
Lymphoma B Cell	Associate	22231447, 33627783, 35806064
Lymphoma Follicular	Associate	36918771
Lymphoma Large B Cell Diffuse	Associate	32186759
Lymphoma Large Cell Anaplastic	Associate	34654390
Lymphoma Mantle Cell	Associate	16052218, 29973234
Lymphoma Non Hodgkin	Stimulate	18519768, 27559738
Lymphoma Non Hodgkin	Associate	22203921, 24885312, 26755002, 27977780, 28187748, 35332092, 35563452, 36720762, 39684714
Lysosomal Storage Diseases	Associate	22259051
Macular Edema	Stimulate	16311351
malar rash	Associate	39327682
Malignant mesenchymal tumor	Associate	15254554
Mallory Weiss Syndrome	Stimulate	20620594
Mammary Analogue Secretory Carcinoma	Associate	31502214
Mammary Neoplasms Animal	Associate	20424164, 2687875, 27569656, 3034598
MASS syndrome	Associate	26045851
Mastocytosis Systemic	Associate	35491845
Maxillary Sinus Neoplasms	Associate	20961443
Medulloblastoma	Associate	16097449, 17039417, 19417143, 23762360, 24986561, 25052069, 26496080
Melanoma	Associate	11494118, 15580309, 16116595, 19213840, 20216471, 21078678, 21738104, 22249266, 23444215, 24200969, 24709886, 25243790, 25339196, 25742786, 25749811 View all (25 more)
Melanoma Cutaneous Malignant	Associate	25243790, 34087900
Meningeal Carcinomatosis	Associate	1739615, 17917328, 19596957, 23804027, 26334749, 27580550, 30851728, 30943730, 31910497, 31929495, 33112047, 34240806
Meningeal Neoplasms	Associate	21610522, 25247337, 29604399, 31777268, 32616581, 32634610, 32711494, 37591896, 38227738, 40439479
Meningioma	Associate	19940402, 20509969, 22623992, 24608452, 30594554, 31077268
Mental Disorders	Associate	34766562
Mesothelioma	Stimulate	14692808
Mesothelioma	Associate	16077404, 20942962, 2372497, 24762959, 36471440, 7947089
Mesothelioma Malignant	Associate	14692808, 15756029, 15867774, 16077404, 16206294, 19781955, 20122271, 20942962, 21124760, 21774103, 21970874, 23558893, 2372497, 30499112, 31752449, 36683050 View all (1 more)
Metaplasia	Associate	28731047
Microsatellite Instability	Associate	23565769, 32264863, 35474354
Microsatellite Instability	Stimulate	28591715
Microsatellite Instability	Inhibit	31924107
Mitochondrial Diseases	Associate	36999607
Monoclonal Gammopathy of Undetermined Significance	Associate	30134812
Mouth Diseases	Associate	17096152, 18379350, 21990607, 35488777
Mouth Diseases	Stimulate	20332305
Mouth Neoplasms	Associate	12915878, 16007067, 16799709, 18347929, 20302655, 20332305, 20570883, 21304522, 22825335, 23806066, 24412287, 24928086, 25029526, 25799278, 26462152 View all (9 more)
Mucocutaneous Lymph Node Syndrome	Associate	30654760
Mucopolysaccharidosis III	Associate	34750392
Mucopolysaccharidosis IV	Associate	40439479
Multiple Myeloma	Associate	14576062, 15735670, 16732320, 22359328, 25894462, 26496024, 27246973, 28492226, 34592762
Multiple Pulmonary Nodules	Associate	20087229, 29247171
Multiple Trauma	Associate	27246973
Myasthenia Gravis	Stimulate	7629292
Myeloproliferative Disorder Chronic with Eosinophilia	Associate	23018906, 28618947
Myocardial Infarction	Associate	29328373
Myocardial Ischemia	Associate	22732799
Myoepithelioma	Associate	32505185
Myofibrillar Myopathy	Associate	34830320
Myopia	Associate	35586671
Myotonia with Skeletal Abnormalities and Mental Retardation	Associate	26790969
Myotonic Dystrophy	Associate	30130447, 36230978
Myxoma	Associate	26563368
Nasal Polyps	Associate	27285994, 29746583
Nasopharyngeal Carcinoma	Associate	10665644, 15796181, 17881446, 19756373, 21388911, 24499623, 25536598, 25963410, 27671677, 28256603, 28581676, 29582644, 29973197, 33875643, 34268932 View all (6 more)
Nasopharyngeal Carcinoma	Stimulate	7769701
Nausea	Associate	38064607
Necrosis	Associate	23619604
Nemaline myopathy 5	Associate	29849818, 32790013
Neoplasm Invasiveness	Associate	16424897, 18379350, 20473902, 24551297, 32616581, 3426916, 37121213, 7819039
Neoplasm Metastasis	Associate	10556937, 10985391, 14706341, 15073595, 15220376, 15335267, 15802268, 15867774, 16007067, 16619582, 16739351, 16865406, 17541441, 17579627, 18166836 View all (333 more)
Neoplasm Metastasis	Stimulate	11494118, 17607370, 23867504, 24052437, 29858031, 31129149, 36572759, 40604601
Neoplasm Metastasis	Inhibit	17465216, 23558893, 25057166, 30679310, 36284372, 36862005
Neoplasm Recurrence Local	Associate	23174717, 36149029, 37248810
Neoplasm Residual	Associate	34798865
Neoplasms	Associate	10037277, 10096969, 10190311, 10214946, 10329596, 10436007, 10645226, 10888627, 10908564, 10995035, 11000224, 11087732, 11116146, 11226409, 11302336 View all (1997 more)
Neoplasms	Inhibit	11546792, 18304967, 18650488, 22847020, 23633104, 23991224, 25106647, 25158139, 25417703, 25758528, 27761967, 29580950, 29899551, 30075033, 30462160 View all (9 more)
Neoplasms	Stimulate	16082192, 19145479, 19525925, 20151982, 20424164, 20620594, 20693797, 20820870, 21431872, 22493441, 23167414, 23370473, 23785399, 23942070, 24321281 View all (28 more)
Neoplasms Basal Cell	Associate	7819052
Neoplasms by Histologic Type	Associate	35641204
Neoplasms Cystic Mucinous and Serous	Associate	11371228, 12377812, 19272638, 20495538, 26254613
Neoplasms Germ Cell and Embryonal	Associate	12124830, 12796025, 28320414
Neoplasms Glandular and Epithelial	Associate	25219648, 34031426, 38591867
Neoplasms Mesothelial	Associate	14692808
Neoplasms Multiple Primary	Associate	21102417
Neoplasms Nerve Tissue	Associate	30689692
Neoplasms Second Primary	Associate	36717819
Neoplasms Squamous Cell	Associate	15253134, 15986037, 16023108, 17283074, 20635059, 22825335, 2372483, 23827819, 25348872, 25348954, 25886585, 27092882, 28859471, 29143497, 29914238 View all (9 more)
Neoplasms Unknown Primary	Associate	21598042, 29443782, 29973234
Neoplastic Syndromes Hereditary	Associate	24736066
Neovascularization Pathologic	Associate	38087190
Nephritis Interstitial	Stimulate	40214391
Nephroma Mesoblastic	Associate	29915264, 35032896
Nephrosis Lipoid	Associate	27165055
Netherton Syndrome	Stimulate	27353319
Neural crest tumor	Associate	27438149
Neuralgia	Associate	26475804, 33771774, 36116508
Neuroblastoma	Associate	18927293, 19414383, 21225506, 21268077, 22990745, 25756510, 26687764, 27216155, 27353319, 30964607, 31475882, 35008802, 35563171
Neuroectodermal Tumors Primitive	Associate	24986561
Neuroendocrine Tumors	Associate	15920550, 23676460, 28538405, 30896637, 35609408, 36307041, 38086335
Neurofibromatosis 1	Associate	34948100
Neurofibromatosis 2	Stimulate	20511180
Neurofibrosarcoma	Associate	17558420, 18448562, 18650488, 18927496, 19246520, 22222570, 22259051, 24341609, 25189642, 37837931
Neurofibrosarcoma	Stimulate	34948100
Neuroma Acoustic	Associate	18670322, 20511180, 21659924, 22222570
Nevus	Associate	35793695
Nevus Pigmented	Associate	1629628, 7963661
Niemann Pick Disease Type C	Associate	35778755
Non alcoholic Fatty Liver Disease	Associate	26845596
Non functioning pancreatic endocrine tumor	Associate	15920550
Non Muscle Invasive Bladder Neoplasms	Associate	19171060, 21308147, 24631944, 27438149, 27626805, 32978523, 33024200, 36737799
Nonseminomatous germ cell tumor	Associate	12796025
Nonsyndromic Holoprosencephaly	Associate	33428063
Obesity	Associate	35027437
Oculocutaneous albinism type 2	Inhibit	19088718
Oculocutaneous albinism type 2	Associate	32340810
Odontogenic Tumors	Associate	21053110
Oligodendroglioma	Stimulate	18507036
Oligodendroglioma	Associate	18544654, 19934553, 21839716
Oligomenorrhea	Associate	32289280
Oligospermia	Associate	8174734
Oncogene Addiction	Associate	29133945
Optic Nerve Glioma	Associate	18234969, 7917918
Organizing Pneumonia	Associate	32999231
Oropharyngeal Neoplasms	Associate	17121883, 17848274, 18474878, 20647773, 22907805, 26949921, 29232380, 30289952, 30414263, 31187548, 33428063, 37081578
Osteoarthritis	Associate	31886203
Osteoarthropathy Primary Hypertrophic	Associate	38358227
Osteoporosis	Associate	26914116, 32620113, 36755691, 38509680
Osteoporotic Fractures	Stimulate	36755691
Osteosarcoma	Associate	16007579, 17184803, 18704985, 25227664, 25551557, 26526352, 29617357, 29751634, 31960764, 33432347, 33917440, 33960631, 34335109, 40676084
Otitis Media	Inhibit	23576001
Otitis Media	Associate	31882485
Ovarian Diseases	Associate	32762950, 37598177, 37883761, 9701727
Ovarian Neoplasms	Associate	10098742, 1457340, 15571614, 15599381, 16554736, 16983702, 17179151, 17433065, 17475671, 17595771, 18182111, 18191993, 18519753, 18559505, 18628764 View all (78 more)
Ovarian Neoplasms	Stimulate	31129149
Overweight	Associate	34836017
Pachyonychia Congenita	Associate	36116508
Pancreatic Carcinoma	Associate	15920550
Pancreatic Intraductal Neoplasms	Associate	12377812
Pancreatic Neoplasms	Stimulate	10615931, 9665487
Pancreatic Neoplasms	Associate	11286473, 11371228, 11469683, 12910515, 15801978, 15970678, 16082196, 16311341, 16575403, 16857803, 17457047, 18676769, 19034673, 19645012, 20124483 View all (60 more)
Pancreatic Neoplasms	Inhibit	27354262
Pancreatitis	Associate	34257550
Pancreatitis Chronic	Associate	15166955
Papilloma	Stimulate	12865943, 17592548
Papilloma	Associate	20131316, 33203919, 34108636
Papilloma Inverted	Associate	24039221, 25931286, 26077310, 27234382, 29145573, 33048186, 33203919, 36580012, 37891239, 38165205
Papillomavirus Infections	Associate	20498858, 25082736, 27223085, 34218257
Papillomavirus Infections	Inhibit	20938670
Paresis	Associate	31088573
Paresthesia	Associate	38432025
Parkinson Disease	Associate	23254265, 33548986
Parkinson Disease	Stimulate	32576586
Parkinson Disease	Inhibit	40405084
Paronychia	Associate	34577852
Paronychia	Inhibit	35291829
Parotid Neoplasms	Associate	18542074
Paroxysmal nonkinesigenic dyskinesia	Associate	36717865
Pelvic Inflammatory Disease	Associate	19252473
Penile Neoplasms	Associate	23819610, 26935231, 28122331, 33917394, 34151841
Peptic Ulcer	Associate	18806258
Periapical Diseases	Associate	39446923
Pericardial Effusion	Associate	17233841, 29719437, 35347923
Periodontal Diseases	Associate	37364780
Periodontitis	Associate	33917440
Peripheral Nervous System Neoplasms	Associate	34948100
Peritoneal Diseases	Associate	14976533
Peritoneal Neoplasms	Associate	14976533
Peritonitis	Associate	22426987, 32483122
Personality Disorders	Associate	17848272, 22194989, 22420963, 26114632, 27461681, 32761886, 34062049, 34665934, 35744950
Phyllodes Tumor	Associate	16258523, 18032821, 25593300, 26832993, 33727697
Phyllodes Tumor of the Prostate	Associate	17192792, 27255162
Pituitary ACTH Hypersecretion	Associate	25930709, 39684597
Pituitary Neoplasms	Associate	15098012, 20644271, 23413122, 25675982, 28660986, 34295309
Plaque Atherosclerotic	Associate	8432873
Pleural Diseases	Associate	26923333, 28253871, 33314737, 33707479, 36161776, 37355521, 37390230, 39596989
Pleural Diseases	Stimulate	28949965
Pleural Effusion	Associate	16827805, 17051834, 17060940, 22528563, 22776705, 24926551, 25635424, 25674250, 26917231, 27173189, 27739449, 30255614, 30526536, 30608413, 30672656 View all (11 more)
Pleural Effusion	Stimulate	25695223
Pleural Effusion Malignant	Associate	18508816, 21719485, 22525557, 22528563, 23018906, 23888061, 24587142, 25239875, 26338423, 27216707, 27352172, 28618947, 28934846, 30565433, 30804147 View all (9 more)
Pneumatosis Cystoides Intestinalis	Associate	30819142
Pneumocephalus	Associate	34488370
Pneumonia	Associate	32374485, 33663064, 34958928, 35181498
Pneumonia Pneumocystis	Associate	26198262
Pneumothorax	Associate	27794396
Poikiloderma of Kindler	Inhibit	30248333
Polycystic Kidney Autosomal Dominant	Associate	16797938, 25180832
Polycystic Kidney Diseases	Associate	21697238
Polycystic liver disease	Associate	18587325
Polycystic Ovary Syndrome	Associate	26416764, 28004769, 32289280
Polycythemia Vera	Associate	28550306
Polypoidal Choroidal Vasculopathy	Associate	36622089
Polyps	Associate	1419612, 20210241
Polyradiculoneuropathy Chronic Inflammatory Demyelinating	Associate	33408168
Popliteal Pterygium Syndrome	Associate	24105277
Poroma	Associate	20208479, 23056620
Postoperative Hemorrhage	Associate	26808114, 34447289
Preauricular Tag Isolated Autosomal Dominant 1	Associate	1532884
Precancerous Conditions	Associate	10576656, 35417043
Precursor Cell Lymphoblastic Leukemia Lymphoma	Associate	23936456
Primary granulocytic sarcoma	Associate	26045851
Primary Progressive Nonfluent Aphasia	Associate	36801605
Prodromal Symptoms	Stimulate	14679115
Prodromal Symptoms	Associate	20208477, 28111430, 29447182, 30872465, 33148621, 33501781, 33539970, 33549984, 33787673, 33892800, 34447289, 35014626, 36180314, 36256645, 36429891, 39275932 View all (1 more)
Prolactinoma	Associate	24287797, 33150390
Prostate Cancer Hereditary 7	Associate	23593148, 28039167
Prostatic Hyperplasia	Associate	8650201
Prostatic Neoplasms	Associate	10360641, 10638988, 11330643, 12616956, 12712332, 12841683, 14735192, 15720812, 16397033, 16741920, 16804520, 16970944, 17436590, 17823122, 18386291 View all (55 more)
Prostatic Neoplasms	Stimulate	22493441
Prostatic Neoplasms Castration Resistant	Associate	14735192, 18645679, 21559022, 27916908, 30620391, 35286517
Prostatic stromal proliferation of uncertain malignant potential	Associate	24880441
Prostatitis	Associate	12616956, 14735192, 16152586, 16741920, 16804520, 17598908, 18350153, 19294521, 27713116, 34321039, 35672281, 8650201, 9528825
Protein Deficiency	Associate	22686199
Proteinuria	Associate	17622313
Pruritus	Associate	27938998, 38432025
Pseudolymphoma	Stimulate	10951287
Pseudomonas Infections	Associate	34573440
Psoriasis	Associate	11173656, 1532884
Psoriasis	Stimulate	40405084
Psychotic Disorders	Associate	24743863
Pulmonary Disease Chronic Obstructive	Associate	24828666, 24978309, 25925667, 26346976, 27561911, 28345955, 28522810, 30280794, 35634326, 35860812, 37442582
Pulmonary Disease Chronic Obstructive	Inhibit	26555338
Pulmonary Disease Chronic Obstructive	Stimulate	27008036
Pyruvate Carboxylase Deficiency Disease	Associate	22087246, 22384099, 26725183
Radiation Injuries	Associate	23341526, 34111559, 36530656
Radiation Pneumonitis	Associate	33501781
Radicular Cyst	Associate	23207846
Rectal Neoplasms	Associate	15967033, 17311026, 18182986, 19050903, 19368728, 20843314, 26799287, 27062700, 30001205, 34188197, 34706519
Recurrence	Associate	15986037, 36720507
Reflex Abnormal	Associate	31088573
Renal Insufficiency	Inhibit	30837448
Renal Insufficiency Chronic	Associate	17622313
Respiratory Distress Syndrome	Associate	39334060
Respiratory Tract Infections	Associate	33663064
Retinal Dysplasia	Associate	12762344, 16158937, 1696918, 17877424, 31421471, 35897137, 37482844
Retinal Dysplasia	Stimulate	27559738
Retinal Neoplasms	Associate	32058355
Retinoblastoma	Stimulate	31173241
Retrograde Degeneration	Associate	40474176
Rhabdoid Tumor	Associate	11267936
Rhabdomyosarcoma	Associate	17896786
Rhabdomyosarcoma Embryonal	Associate	16729016
Rickets Hypophosphatemic	Inhibit	30192383
Rickets Hypophosphatemic	Associate	30192383
Rufous oculocutaneous albinism	Associate	29402243, 40429751
Salivary Duct Calculi	Associate	20371674, 25343854, 30484070
Salivary Gland Neoplasms	Associate	18542074, 19309723, 19547661, 20664595, 22240798, 23361279, 23933559, 25012870, 28377929, 34232601, 35241559
Sarcoma	Associate	15772959, 16461571, 20118913, 26526352, 28556791, 29394136, 29703606, 29881993, 30513863
Sarcoma	Stimulate	19781955
Sarcoma Clear Cell	Associate	16867224
Sarcoma Ewing	Associate	24590121
Sarcoma Synovial	Associate	14507652, 15641030, 16514409, 18448562, 29893303
Schizophrenia	Associate	24743863, 28117656
Schizophrenia	Stimulate	2984254
Scleroderma Diffuse	Inhibit	33131208
Scleroderma Systemic	Associate	35663995
Sebaceous gland hyperplasia familial presenile	Associate	26804118
Sebaceous Gland Neoplasms	Associate	26804118
Secretory breast carcinoma	Associate	31502214
Segawa syndrome autosomal recessive	Inhibit	32292093
Seizures	Associate	25153654, 26808114
Seminoma	Stimulate	20608935
Sepsis	Associate	36344490
Sertoli Cell Only Syndrome	Associate	8174734
Severe Acute Respiratory Syndrome	Associate	12762344, 38375886
Sexual Dysfunction Physiological	Associate	18000506, 33548986
Sick Sinus Syndrome	Associate	15829495
Sigmoid Neoplasms	Associate	25437589
Sinonasal undifferentiated carcinoma	Associate	23633104, 33048186, 33203919, 36946265
Sinus Thrombosis Intracranial	Associate	31929495
Skin Diseases	Associate	1532884, 15865067, 17106442, 17410005, 17878175, 22117530, 25219648, 25707609, 27165055, 27938998, 30557370, 36232814
Skin Diseases	Inhibit	26475804, 27467256
Skin Neoplasms	Associate	23430747
Skull Base Neoplasms	Associate	20670138
Sleep Disorders Circadian Rhythm	Associate	37221352
Small Cell Lung Carcinoma	Associate	17784875, 20683448, 21178714, 21430269, 21718596, 24195468, 24457237, 24828667, 24913109, 24978188, 25355724, 25700797, 25758528, 26400668, 26752677 View all (47 more)
Smoke Inhalation Injury	Stimulate	15563701, 23932486, 40345896
Smoke Inhalation Injury	Associate	27371767, 28345955, 32047821, 36341427
Smoke Inhalation Injury	Inhibit	29489642, 30868748, 31436246
Soft Tissue Neoplasms	Associate	15254554, 19648884, 39577666
Solitary Pulmonary Nodule	Associate	19844187, 33002403, 34393158, 37579253
Spastic paraplegia 15 autosomal recessive	Associate	30081747
Spastic paraplegia 20 autosomal recessive	Associate	17332501
Spinal Cord Compression	Associate	36477376
Spinal Cord Neoplasms	Associate	31229973
Spinal Fractures	Inhibit	30837448
Spinal Muscular Atrophies of Childhood	Associate	35484883
Spinocerebellar Degenerations	Associate	32772458
Squamous Cell Carcinoma of Head and Neck	Associate	10096253, 12771142, 12942316, 15144956, 15205458, 15692721, 15842252, 16158919, 16547470, 16799709, 16984731, 17132224, 17431120, 17486071, 18225538 View all (217 more)
Squamous Cell Carcinoma of Head and Neck	Stimulate	19204206
Squamous Cell Carcinoma of Head and Neck	Inhibit	25563452, 34272446
Squamous Intraepithelial Lesions	Associate	22203921, 24551297, 24966959
Status Asthmaticus	Stimulate	11698473
Status Asthmaticus	Associate	15929951, 26243279, 30639343
Stomach Diseases	Associate	28222666, 29379775, 31034158
Stomach Neoplasms	Associate	10037277, 10480573, 11680933, 12618892, 15073595, 15161014, 15556605, 15647181, 16816379, 17094480, 17431415, 17433039, 17922051, 18199332, 18224443 View all (97 more)
Stomach Neoplasms	Stimulate	25959250
Stomach Ulcer	Inhibit	12641822
Stroke	Associate	34107910, 35862191
Substance Related Disorders	Associate	18711136, 23752247
Superior Vena Cava Syndrome	Associate	29590083
Supranuclear Palsy Progressive	Associate	28271184
Supratentorial Neoplasms	Associate	20708924, 21059755
Sveinsson Chorioretinal Atrophy	Associate	21455841
Syndrome	Associate	20064244, 23144692, 27552105
Tachycardia Atrioventricular Nodal Reentry	Associate	18629779, 20873989
Tarlov Cysts	Associate	38358186
Teratoma	Associate	12783324
Tertiary Lymphoid Structures	Associate	18505086, 20430737, 25154973, 25593477, 26599344, 28854970, 32600105, 34948746
Tertiary Lymphoid Structures	Stimulate	25953424
Tertiary Lymphoid Structures	Inhibit	27761967
Testicular Diseases	Associate	8174734
Testicular Germ Cell Tumor	Associate	12783324, 20608935, 28320414, 34882061
Tetralogy of Fallot	Associate	24479926
Thalamic Diseases	Associate	24285547
Thoracic Injuries	Associate	30817606
Thromboembolism	Associate	33314597, 36493600, 37232831
Thrombosis	Associate	35938548
Thymic epithelial tumor	Associate	11935304, 22700994
Thymoma	Associate	11935304, 15630697, 32388277, 33835620, 35092378, 7629292
Thymus Neoplasms	Associate	11935304, 22700994
Thyroid cancer medullary	Associate	27409604
Thyroid Cancer Papillary	Associate	20877637, 23569038, 23746767, 25031742, 28947799, 29665129, 32685551, 32767330, 33592140, 36510281
Thyroid Carcinoma Anaplastic	Associate	17079354, 28489587, 29849821, 36094870
Thyroid Neoplasms	Associate	12471003, 1699752, 17158762, 20237991, 23746767, 23917679, 26695142, 28757314, 33267781, 33874989, 36094870, 36510281
Thyroid Neoplasms	Stimulate	29849821
Thyroid Nodule	Associate	20087229, 31699841, 32296586, 34749486
Tight skin contracture syndrome lethal	Associate	11173656
Tn Syndrome	Associate	23124476
Tongue Neoplasms	Associate	34201116
Tooth Erosion	Associate	24691054
Trifunctional Protein Deficiency With Myopathy And Neuropathy	Associate	39327682
Triple Negative Breast Neoplasms	Associate	17598908, 18266105, 18950515, 19150933, 19855377, 21120307, 21276138, 21457545, 21656328, 22293080, 22579283, 22638807, 22665533, 22788954, 22957061 View all (86 more)
Triple Negative Breast Neoplasms	Stimulate	21966417, 23082819, 25966200, 32806648, 36853320
Trochlear Nerve Diseases	Associate	27211795
Tuberculosis	Associate	22173705, 25634180, 26927994, 33663064
Tuberculosis	Stimulate	29621876
Tuberculosis Extrapulmonary	Associate	23599147
Tuberculosis Multidrug Resistant	Associate	20942457, 27220321, 29450946, 34065402
Tuberculosis Pulmonary	Associate	22173705, 33663064
Tuberculosis Pulmonary	Stimulate	29621876
Tuberous Sclerosis	Associate	35084981
Tuberous Sclerosis 1	Associate	36231025
Turcot syndrome	Associate	24800948, 28591715, 38066711
Tyrosine Kinase 2 Deficiency	Associate	19949011, 23714228, 27268079, 27821794, 34548309, 37920971
Tyrosine Kinase 2 Deficiency	Inhibit	20635059, 22502680, 31361375, 32634610
Ulcer	Associate	27062700
Unconsciousness	Associate	37143409
Urachal cancer	Associate	27178450, 27283768
Uremia	Associate	37773677
Urethral Neoplasms	Associate	16965395, 18006009, 22406363, 23827819, 24186136, 27044931, 28388586, 39609964
Urinary Bladder Diseases	Associate	1712624, 27870887
Urinary Bladder Neoplasms	Associate	10995035, 15583696, 15611794, 16685269, 17311025, 17394193, 17909029, 18006009, 18234962, 19171060, 19287975, 19372140, 19671845, 19881954, 20407012 View all (42 more)
Urinary Bladder Neoplasms	Stimulate	23251617, 25719831, 28285559, 29456764, 33426060, 7819052
Urologic Neoplasms	Associate	24065479, 27870887
Urticaria	Associate	32461525
Usher syndrome type 2A	Associate	36751700
Uterine Cervical Dysplasia	Associate	11788593, 1696918, 21982220, 26339400
Uterine Cervical Neoplasms	Associate	11275796, 11788593, 12967482, 17316357, 18629779, 18700025, 19654571, 21252859, 21305029, 21424032, 21982220, 23927961, 23936413, 24037752, 24551297 View all (30 more)
Uterine Cervical Neoplasms	Stimulate	31922210
Uterine Cervicitis	Associate	24551297, 24966959, 27223085
Uterine Diseases	Associate	37257767
Uterine Neoplasms	Associate	25981989, 32994315
Uveal melanoma	Associate	30571927
Varicose Veins	Associate	31432124
Vascular Calcification	Associate	36930472
Vascular Diseases	Associate	15734884
Vascular System Injuries	Associate	33549061
Vasculitis	Associate	35457163
Venous Thromboembolism	Associate	29743116
Venous Thrombosis	Associate	22533697, 34180588, 37232831
Virus Diseases	Associate	23255786
Vision Disorders	Associate	33272243
Vitamin K Deficiency	Stimulate	17699110
Vomiting	Associate	32393286
Vulvar Neoplasms	Associate	16963112, 31844270
Weight Loss	Associate	34836017, 36905787
Wilms Tumor	Associate	20944147, 37058032
Winter Shortland Temple syndrome	Associate	21273531
Wiskott Aldrich Syndrome	Stimulate	20018733
Wolf Hirschhorn Syndrome	Associate	29291705
X Linked Combined Immunodeficiency Diseases	Associate	25272957, 34242789
Xanthomatosis	Associate	40275124
Zinc Deficiency Neonatal due to Low Breast Milk Zinc	Stimulate	35216384

EGFR (epidermal growth factor receptor)