Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
1634
Gene name Gene Name - the full gene name approved by the HGNC.
Decorin
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
DCN
Synonyms (NCBI Gene) Gene synonyms aliases
CSCD, DSPG2, PG40, PGII, PGS2, SLRR1B
Disease Acronyms (UniProt) Disease acronyms from UniProt database
CSCD
Chromosome Chromosome number
12
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
12q21.33
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a member of the small leucine-rich proteoglycan family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature prot
SNPs SNP information provided by dbSNP.
SNP ID Visualize variation Clinical significance Consequence
rs80338741 A>- Pathogenic Frameshift variant, coding sequence variant, 3 prime UTR variant
rs80338742 G>- Pathogenic Frameshift variant, coding sequence variant, 3 prime UTR variant
rs397515545 C>- Pathogenic Frameshift variant, coding sequence variant, 3 prime UTR variant
rs587777258 T>- Pathogenic Coding sequence variant, frameshift variant, 3 prime UTR variant
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT926407 hsa-miR-3647-3p CLIP-seq
MIRT926408 hsa-miR-4766-5p CLIP-seq
MIRT926409 hsa-miR-4282 CLIP-seq
MIRT926410 hsa-miR-4698 CLIP-seq
MIRT926411 hsa-miR-548c-3p CLIP-seq
Transcription factors
Transcription factor Regulation Reference
JUN Repression 8798756
NR1H4 Activation 18514055
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0001822 Process Kidney development IEA
GO:0001890 Process Placenta development IEA
GO:0003723 Function RNA binding HDA 22658674
GO:0005515 Function Protein binding IPI 1747115, 11598131, 20026052, 25331875, 25789606
GO:0005518 Function Collagen binding IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
125255 2705 ENSG00000011465
Protein
UniProt ID P07585
Protein name Decorin (Bone proteoglycan II) (PG-S2) (PG40)
Protein function May affect the rate of fibrils formation.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01462 LRRNT 53 80 Leucine rich repeat N-terminal domain Family
PF13855 LRR_8 81 141 Leucine rich repeat Repeat
PF13855 LRR_8 150 218 Leucine rich repeat Repeat
PF13855 LRR_8 221 281 Leucine rich repeat Repeat
Tissue specificity TISSUE SPECIFICITY: Detected in placenta (at protein level) (PubMed:32337544). Detected in cerebrospinal fluid, fibroblasts and urine (at protein level) (PubMed:25326458, PubMed:36213313, PubMed:37453717). {ECO:0000269|PubMed:25326458, ECO:0000269|PubMed:
Sequence
Sequence length 359
Interactions View interactions