CTNND1 (catenin delta 1)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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1500 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Catenin delta 1 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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CTNND1 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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BCDS2, CAS, CTNND, P120CAS, P120CTN, p120, p120(CAS), p120(CTN) |
Disease Acronyms (UniProt)
Disease acronyms from UniProt database
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BCDS2 |
Chromosome
Chromosome number
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11 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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11q12.1 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the Armadillo protein family, which function in adhesion between cells and signal transduction. Multiple translation initiation codons and alternative splicing result in many different isoforms being translated. Not all of th |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||||||||||||
UniProt ID | O60716 | ||||||||||||||||||||
Protein name | Catenin delta-1 (Cadherin-associated Src substrate) (CAS) (p120 catenin) (p120(ctn)) (p120(cas)) | ||||||||||||||||||||
Protein function | Key regulator of cell-cell adhesion that associates with and regulates the cell adhesion properties of both C-, E- and N-cadherins, being critical for their surface stability (PubMed:14610055, PubMed:20371349). Promotes localization and retentio | ||||||||||||||||||||
PDB | 3L6X , 3L6Y | ||||||||||||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Expressed in vascular endothelium. Melanocytes and melanoma cells primarily express the long isoform 1A, whereas keratinocytes express shorter isoforms, especially 3A. The shortest isoform 4A, is detected in normal keratinocytes and me | ||||||||||||||||||||
Sequence |
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Sequence length | 968 | ||||||||||||||||||||
Interactions | View interactions |
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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