Gene Gene information from NCBI Gene database.
Entrez ID 1431
Gene name Citrate synthase
Gene symbol CS
Synonyms (NCBI Gene)
-
Chromosome 12
Chromosome location 12q13.3
Summary The protein encoded by this gene is a Krebs tricarboxylic acid cycle enzyme that catalyzes the synthesis of citrate from oxaloacetate and acetyl coenzyme A. The enzyme is found in nearly all cells capable of oxidative metablism. This protein is nuclear en
miRNA miRNA information provided by mirtarbase database.
708
miRTarBase ID miRNA Experiments Reference
MIRT032306 hsa-let-7b-5p Proteomics 18668040
MIRT052406 hsa-let-7a-5p CLASH 23622248
MIRT052406 hsa-let-7a-5p CLASH 23622248
MIRT050008 hsa-miR-28-5p CLASH 23622248
MIRT047152 hsa-miR-183-5p CLASH 23622248
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
22
GO ID Ontology Definition Evidence Reference
GO:0003723 Function RNA binding HDA 22681889
GO:0005634 Component Nucleus HDA 21630459
GO:0005739 Component Mitochondrion HDA 20833797
GO:0005739 Component Mitochondrion HTP 34800366
GO:0005739 Component Mitochondrion IDA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
118950 2422 ENSG00000062485
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
O75390
Protein name Citrate synthase, mitochondrial (EC 2.3.3.1) (Citrate (Si)-synthase)
Protein function Key enzyme of the Krebs tricarboxylic acid cycle which catalyzes the synthesis of citrate from acetyl coenzyme A and oxaloacetate.
PDB 5UZP , 5UZQ , 5UZR
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00285 Citrate_synt 71 450 Citrate synthase, C-terminal domain Domain
Sequence
Sequence length 466
Interactions View interactions