CAMKK2 (calcium/calmodulin dependent protein kinase kinase 2)

Gene

• Entrez ID: 10645
• Gene name: Calcium/calmodulin dependent protein kinase kinase 2
• Gene symbol: CAMKK2
• Synonyms (NCBI Gene): CAMKK, CAMKKB
• Chromosome: 12
• Chromosome location: 12q24.31
• Summary: The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosph

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT027179	hsa-miR-103a-3p	Sequencing	20371350
MIRT031851	hsa-miR-16-5p	Sequencing	20371350
MIRT048541	hsa-miR-100-5p	CLASH	23622248
MIRT045326	hsa-miR-185-5p	CLASH	23622248
MIRT688870	hsa-miR-6854-5p	HITS-CLIP	23313552
MIRT688869	hsa-miR-5584-5p	HITS-CLIP	23313552
MIRT688868	hsa-miR-6750-5p	HITS-CLIP	23313552
MIRT688867	hsa-miR-6822-5p	HITS-CLIP	23313552
MIRT688866	hsa-miR-9500	HITS-CLIP	23313552
MIRT688865	hsa-miR-1288-5p	HITS-CLIP	23313552
MIRT688864	hsa-miR-4330	HITS-CLIP	23313552
MIRT688863	hsa-miR-3664-3p	HITS-CLIP	23313552
MIRT688862	hsa-miR-1289	HITS-CLIP	23313552
MIRT688861	hsa-miR-4294	HITS-CLIP	23313552
MIRT688860	hsa-miR-8078	HITS-CLIP	23313552
MIRT688859	hsa-miR-7847-3p	HITS-CLIP	23313552
MIRT688858	hsa-miR-3911	HITS-CLIP	23313552
MIRT688857	hsa-miR-644a	HITS-CLIP	23313552
MIRT688856	hsa-miR-5100	HITS-CLIP	23313552
MIRT688855	hsa-miR-579-3p	HITS-CLIP	23313552
MIRT688854	hsa-miR-664b-3p	HITS-CLIP	23313552
MIRT688853	hsa-miR-3198	HITS-CLIP	23313552
MIRT688852	hsa-miR-4309	HITS-CLIP	23313552
MIRT688851	hsa-miR-6818-5p	HITS-CLIP	23313552
MIRT688850	hsa-miR-147a	HITS-CLIP	23313552
MIRT688870	hsa-miR-6854-5p	HITS-CLIP	23313552
MIRT688869	hsa-miR-5584-5p	HITS-CLIP	23313552
MIRT688868	hsa-miR-6750-5p	HITS-CLIP	23313552
MIRT688867	hsa-miR-6822-5p	HITS-CLIP	23313552
MIRT688866	hsa-miR-9500	HITS-CLIP	23313552
MIRT688865	hsa-miR-1288-5p	HITS-CLIP	23313552
MIRT688864	hsa-miR-4330	HITS-CLIP	23313552
MIRT688863	hsa-miR-3664-3p	HITS-CLIP	23313552
MIRT688862	hsa-miR-1289	HITS-CLIP	23313552
MIRT688861	hsa-miR-4294	HITS-CLIP	23313552
MIRT688860	hsa-miR-8078	HITS-CLIP	23313552
MIRT688859	hsa-miR-7847-3p	HITS-CLIP	23313552
MIRT688858	hsa-miR-3911	HITS-CLIP	23313552
MIRT688857	hsa-miR-644a	HITS-CLIP	23313552
MIRT688856	hsa-miR-5100	HITS-CLIP	23313552
MIRT688855	hsa-miR-579-3p	HITS-CLIP	23313552
MIRT688854	hsa-miR-664b-3p	HITS-CLIP	23313552
MIRT688853	hsa-miR-3198	HITS-CLIP	23313552
MIRT688852	hsa-miR-4309	HITS-CLIP	23313552
MIRT688851	hsa-miR-6818-5p	HITS-CLIP	23313552
MIRT688850	hsa-miR-147a	HITS-CLIP	23313552
MIRT860471	hsa-miR-1275	CLIP-seq
MIRT860472	hsa-miR-140-5p	CLIP-seq
MIRT860473	hsa-miR-198	CLIP-seq
MIRT860474	hsa-miR-342-5p	CLIP-seq
MIRT860475	hsa-miR-409-5p	CLIP-seq
MIRT860476	hsa-miR-4447	CLIP-seq
MIRT860477	hsa-miR-4472	CLIP-seq
MIRT860478	hsa-miR-4481	CLIP-seq
MIRT860479	hsa-miR-4525	CLIP-seq
MIRT860480	hsa-miR-4651	CLIP-seq
MIRT860481	hsa-miR-4664-5p	CLIP-seq
MIRT860482	hsa-miR-4665-5p	CLIP-seq
MIRT860483	hsa-miR-4723-5p	CLIP-seq
MIRT860484	hsa-miR-4729	CLIP-seq
MIRT860485	hsa-miR-4745-5p	CLIP-seq
MIRT860486	hsa-miR-4757-3p	CLIP-seq
MIRT860487	hsa-miR-4758-5p	CLIP-seq
MIRT860488	hsa-miR-608	CLIP-seq
MIRT860489	hsa-miR-625	CLIP-seq
MIRT860490	hsa-miR-122	CLIP-seq
MIRT860491	hsa-miR-1587	CLIP-seq
MIRT860492	hsa-miR-4280	CLIP-seq
MIRT860493	hsa-miR-4492	CLIP-seq
MIRT860494	hsa-miR-4498	CLIP-seq
MIRT860495	hsa-miR-4656	CLIP-seq
MIRT860496	hsa-miR-4674	CLIP-seq
MIRT860497	hsa-miR-4675	CLIP-seq
MIRT860498	hsa-miR-4711-3p	CLIP-seq
MIRT860499	hsa-miR-4741	CLIP-seq
MIRT860500	hsa-miR-4778-3p	CLIP-seq
MIRT860501	hsa-miR-635	CLIP-seq
MIRT860502	hsa-miR-762	CLIP-seq
MIRT860503	hsa-miR-1200	CLIP-seq
MIRT860504	hsa-miR-127-5p	CLIP-seq
MIRT860505	hsa-miR-1305	CLIP-seq
MIRT860506	hsa-miR-132	CLIP-seq
MIRT860507	hsa-miR-153	CLIP-seq
MIRT860508	hsa-miR-154	CLIP-seq
MIRT860509	hsa-miR-1913	CLIP-seq
MIRT860510	hsa-miR-1972	CLIP-seq
MIRT860511	hsa-miR-212	CLIP-seq
MIRT860512	hsa-miR-3074-5p	CLIP-seq
MIRT860513	hsa-miR-3159	CLIP-seq
MIRT860514	hsa-miR-3189-5p	CLIP-seq
MIRT860515	hsa-miR-3194-5p	CLIP-seq
MIRT860516	hsa-miR-324-3p	CLIP-seq
MIRT860517	hsa-miR-331-3p	CLIP-seq
MIRT860518	hsa-miR-3690	CLIP-seq
MIRT860519	hsa-miR-380	CLIP-seq
MIRT860520	hsa-miR-411	CLIP-seq
MIRT860521	hsa-miR-421	CLIP-seq
MIRT860522	hsa-miR-4254	CLIP-seq
MIRT860523	hsa-miR-4292	CLIP-seq
MIRT860524	hsa-miR-4313	CLIP-seq
MIRT860525	hsa-miR-4640-5p	CLIP-seq
MIRT860526	hsa-miR-4652-3p	CLIP-seq
MIRT860527	hsa-miR-4684-5p	CLIP-seq
MIRT860528	hsa-miR-4691-3p	CLIP-seq
MIRT860529	hsa-miR-4709-5p	CLIP-seq
MIRT860530	hsa-miR-4717-3p	CLIP-seq
MIRT860531	hsa-miR-4726-5p	CLIP-seq
MIRT860532	hsa-miR-4731-3p	CLIP-seq
MIRT860533	hsa-miR-4733-3p	CLIP-seq
MIRT860534	hsa-miR-4738-3p	CLIP-seq
MIRT860535	hsa-miR-4755-3p	CLIP-seq
MIRT860536	hsa-miR-4758-3p	CLIP-seq
MIRT860537	hsa-miR-4801	CLIP-seq
MIRT860538	hsa-miR-4802-3p	CLIP-seq
MIRT860539	hsa-miR-671-5p	CLIP-seq
MIRT860540	hsa-miR-942	CLIP-seq
MIRT1922654	hsa-miR-299-3p	CLIP-seq
MIRT1922655	hsa-miR-3151	CLIP-seq
MIRT1922656	hsa-miR-3607-5p	CLIP-seq
MIRT1922657	hsa-miR-3692	CLIP-seq
MIRT860476	hsa-miR-4447	CLIP-seq
MIRT860477	hsa-miR-4472	CLIP-seq
MIRT1922658	hsa-miR-4736	CLIP-seq
MIRT1922659	hsa-miR-486-3p	CLIP-seq
MIRT1922660	hsa-miR-491-5p	CLIP-seq
MIRT1955332	hsa-miR-1245b-3p	CLIP-seq
MIRT860504	hsa-miR-127-5p	CLIP-seq
MIRT1955333	hsa-miR-129-5p	CLIP-seq
MIRT1955334	hsa-miR-2355-3p	CLIP-seq
MIRT1955335	hsa-miR-3127-3p	CLIP-seq
MIRT1955336	hsa-miR-3202	CLIP-seq
MIRT1955337	hsa-miR-362-5p	CLIP-seq
MIRT1955338	hsa-miR-4533	CLIP-seq
MIRT1955339	hsa-miR-4646-3p	CLIP-seq
MIRT860530	hsa-miR-4717-3p	CLIP-seq
MIRT1955340	hsa-miR-500b	CLIP-seq
MIRT1955341	hsa-miR-501-5p	CLIP-seq
MIRT1955342	hsa-miR-1184	CLIP-seq
MIRT1955343	hsa-miR-1301	CLIP-seq
MIRT1955335	hsa-miR-3127-3p	CLIP-seq
MIRT1955344	hsa-miR-3148	CLIP-seq
MIRT1955345	hsa-miR-3160-5p	CLIP-seq
MIRT1955346	hsa-miR-3179	CLIP-seq
MIRT860515	hsa-miR-3194-5p	CLIP-seq
MIRT1922657	hsa-miR-3692	CLIP-seq
MIRT1955347	hsa-miR-4461	CLIP-seq
MIRT860534	hsa-miR-4738-3p	CLIP-seq
MIRT1955348	hsa-miR-4797-5p	CLIP-seq
MIRT1955349	hsa-miR-5047	CLIP-seq
MIRT1955350	hsa-miR-627	CLIP-seq
MIRT860539	hsa-miR-671-5p	CLIP-seq
MIRT2193089	hsa-miR-1179	CLIP-seq
MIRT1955342	hsa-miR-1184	CLIP-seq
MIRT2193090	hsa-miR-1207-3p	CLIP-seq
MIRT2193091	hsa-miR-1234	CLIP-seq
MIRT860504	hsa-miR-127-5p	CLIP-seq
MIRT2193092	hsa-miR-1283	CLIP-seq
MIRT2193093	hsa-miR-1299	CLIP-seq
MIRT860505	hsa-miR-1305	CLIP-seq
MIRT2193094	hsa-miR-1323	CLIP-seq
MIRT2193095	hsa-miR-185	CLIP-seq
MIRT860473	hsa-miR-198	CLIP-seq
MIRT2193096	hsa-miR-2355-5p	CLIP-seq
MIRT2193097	hsa-miR-3135b	CLIP-seq
MIRT860513	hsa-miR-3159	CLIP-seq
MIRT2193098	hsa-miR-3190	CLIP-seq
MIRT860515	hsa-miR-3194-5p	CLIP-seq
MIRT2193099	hsa-miR-338-3p	CLIP-seq
MIRT2193100	hsa-miR-3646	CLIP-seq
MIRT2193101	hsa-miR-3662	CLIP-seq
MIRT2193102	hsa-miR-3667-5p	CLIP-seq
MIRT2193103	hsa-miR-378	CLIP-seq
MIRT2193104	hsa-miR-378b	CLIP-seq
MIRT2193105	hsa-miR-378c	CLIP-seq
MIRT2193106	hsa-miR-378d	CLIP-seq
MIRT2193107	hsa-miR-378e	CLIP-seq
MIRT2193108	hsa-miR-378f	CLIP-seq
MIRT2193109	hsa-miR-378h	CLIP-seq
MIRT2193110	hsa-miR-378i	CLIP-seq
MIRT2193111	hsa-miR-3919	CLIP-seq
MIRT2193112	hsa-miR-3938	CLIP-seq
MIRT2193113	hsa-miR-3943	CLIP-seq
MIRT2193114	hsa-miR-422a	CLIP-seq
MIRT2193115	hsa-miR-4267	CLIP-seq
MIRT2193116	hsa-miR-4306	CLIP-seq
MIRT2193117	hsa-miR-4310	CLIP-seq
MIRT860524	hsa-miR-4313	CLIP-seq
MIRT2193118	hsa-miR-4323	CLIP-seq
MIRT2193119	hsa-miR-4638-3p	CLIP-seq
MIRT2193120	hsa-miR-4644	CLIP-seq
MIRT860530	hsa-miR-4717-3p	CLIP-seq
MIRT2193121	hsa-miR-4782-5p	CLIP-seq
MIRT1955348	hsa-miR-4797-5p	CLIP-seq
MIRT2193122	hsa-miR-490-5p	CLIP-seq
MIRT2193123	hsa-miR-494	CLIP-seq
MIRT2193124	hsa-miR-512-3p	CLIP-seq
MIRT2193125	hsa-miR-516b	CLIP-seq
MIRT2193126	hsa-miR-520d-5p	CLIP-seq
MIRT2193127	hsa-miR-524-5p	CLIP-seq
MIRT2193128	hsa-miR-548aa	CLIP-seq
MIRT2193129	hsa-miR-548o	CLIP-seq
MIRT2193130	hsa-miR-598	CLIP-seq
MIRT2193131	hsa-miR-634	CLIP-seq
MIRT2193132	hsa-miR-7	CLIP-seq
MIRT2193133	hsa-miR-766	CLIP-seq
MIRT860518	hsa-miR-3690	CLIP-seq
MIRT860522	hsa-miR-4254	CLIP-seq
MIRT860539	hsa-miR-671-5p	CLIP-seq
MIRT2446145	hsa-miR-1228	CLIP-seq
MIRT2446146	hsa-miR-1253	CLIP-seq
MIRT2446147	hsa-miR-140-3p	CLIP-seq
MIRT2446148	hsa-miR-342-3p	CLIP-seq
MIRT2446149	hsa-miR-4251	CLIP-seq
MIRT2446150	hsa-miR-4329	CLIP-seq
MIRT2496170	hsa-miR-105	CLIP-seq
MIRT2496171	hsa-miR-1256	CLIP-seq
MIRT2496172	hsa-miR-1266	CLIP-seq
MIRT2496173	hsa-miR-29a	CLIP-seq
MIRT2496174	hsa-miR-29b	CLIP-seq
MIRT2496175	hsa-miR-29c	CLIP-seq
MIRT2496176	hsa-miR-3119	CLIP-seq
MIRT2496177	hsa-miR-3140-3p	CLIP-seq
MIRT2496178	hsa-miR-3194-3p	CLIP-seq
MIRT2496179	hsa-miR-3689d	CLIP-seq
MIRT2496180	hsa-miR-4436b-5p	CLIP-seq
MIRT2496181	hsa-miR-4487	CLIP-seq
MIRT2496182	hsa-miR-4518	CLIP-seq
MIRT2496183	hsa-miR-4660	CLIP-seq
MIRT860534	hsa-miR-4738-3p	CLIP-seq
MIRT2496184	hsa-miR-4753-5p	CLIP-seq
MIRT2193123	hsa-miR-494	CLIP-seq
MIRT2496185	hsa-miR-548c-3p	CLIP-seq
MIRT860539	hsa-miR-671-5p	CLIP-seq
MIRT2496186	hsa-miR-873	CLIP-seq
MIRT2496187	hsa-miR-885-3p	CLIP-seq
MIRT1955332	hsa-miR-1245b-3p	CLIP-seq
MIRT2496172	hsa-miR-1266	CLIP-seq
MIRT2677340	hsa-miR-1268	CLIP-seq
MIRT2677341	hsa-miR-1268b	CLIP-seq
MIRT2677342	hsa-miR-133a	CLIP-seq
MIRT2677343	hsa-miR-133b	CLIP-seq
MIRT2677344	hsa-miR-188-3p	CLIP-seq
MIRT2496173	hsa-miR-29a	CLIP-seq
MIRT2496174	hsa-miR-29b	CLIP-seq
MIRT2496175	hsa-miR-29c	CLIP-seq
MIRT2677345	hsa-miR-3115	CLIP-seq
MIRT2496179	hsa-miR-3689d	CLIP-seq
MIRT2677346	hsa-miR-3908	CLIP-seq
MIRT2677347	hsa-miR-3942-5p	CLIP-seq
MIRT2677348	hsa-miR-4281	CLIP-seq
MIRT2496180	hsa-miR-4436b-5p	CLIP-seq
MIRT2496182	hsa-miR-4518	CLIP-seq
MIRT2677349	hsa-miR-4703-5p	CLIP-seq
MIRT860534	hsa-miR-4738-3p	CLIP-seq
MIRT2496184	hsa-miR-4753-5p	CLIP-seq
MIRT2677350	hsa-miR-4766-3p	CLIP-seq
MIRT2496185	hsa-miR-548c-3p	CLIP-seq
MIRT2677351	hsa-miR-556-5p	CLIP-seq
MIRT2677352	hsa-miR-585	CLIP-seq
MIRT2677353	hsa-miR-610	CLIP-seq
MIRT2677354	hsa-miR-621	CLIP-seq
MIRT860539	hsa-miR-671-5p	CLIP-seq
MIRT2193132	hsa-miR-7	CLIP-seq
MIRT2496186	hsa-miR-873	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000165	Process	MAPK cascade	TAS	11395482
GO:0000166	Function	Nucleotide binding	IEA
GO:0004672	Function	Protein kinase activity	IEA
GO:0004674	Function	Protein serine/threonine kinase activity	IBA
GO:0004674	Function	Protein serine/threonine kinase activity	IEA
GO:0004683	Function	Calcium/calmodulin-dependent protein kinase activity	IEA
GO:0004713	Function	Protein tyrosine kinase activity	TAS	11395482
GO:0005509	Function	Calcium ion binding	IDA	11395482
GO:0005516	Function	Calmodulin binding	IEA
GO:0005516	Function	Calmodulin binding	TAS	11395482
GO:0005524	Function	ATP binding	IEA
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IEA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	IMP	26103054
GO:0005829	Component	Cytosol	TAS
GO:0006468	Process	Protein phosphorylation	IDA	11395482
GO:0016301	Function	Kinase activity	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0019722	Process	Calcium-mediated signaling	TAS	11395482
GO:0034614	Process	Cellular response to reactive oxygen species	TAS	26103054
GO:0042995	Component	Cell projection	IEA
GO:0043005	Component	Neuron projection	IEA
GO:0045859	Process	Regulation of protein kinase activity	TAS	11395482
GO:0045893	Process	Positive regulation of DNA-templated transcription	TAS	11395482
GO:0046777	Process	Protein autophosphorylation	IDA	11395482
GO:0061762	Process	CAMKK-AMPK signaling cascade	IBA
GO:0061762	Process	CAMKK-AMPK signaling cascade	IMP	26103054
GO:0106310	Function	Protein serine kinase activity	IEA
GO:1903599	Process	Positive regulation of autophagy of mitochondrion	IMP	26103054

Other IDs

• MIM: 615002
• HGNC: 1470
• e!Ensembl: ENSG00000110931

Protein

• UniProt ID: Q96RR4
• Protein name: Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) (CaMKK 2) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-KK beta) (CaM-kinase kinase beta) (CaMKK beta)
• Protein function: Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D
• PDB: 2ZV2, 5UY6, 5UYJ, 5VT1, 5YV8, 5YV9, 5YVA, 5YVB, 5YVC, 6BKU, 6BLE, 6BQL, 6BQP, 6BQQ, 6BRC, 6CMJ, 6EF5, 6EWW, 6FEL, 6Y3O, 6Y4K, 6Y6B, 6Y8A, 8TUC
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00069	Pkinase	165 → 446	Protein kinase domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Ubiquitously expressed with higher levels in the brain. Intermediate levels are detected in spleen, prostate, thyroid and leukocytes. The lowest level is in lung. {ECO:0000269|PubMed:9662074}.
• Sequence:

  MSSCVSSQPSSNRAAPQDELGGRGSSSSESQKPCEALRGLSSLSIHLGMESFIVVTECEP
  GCAVDLGLARDRPLEADGQEVPLDTSGSQARPHLSGRKLSLQERSQGGLAAGGSLDMNGR
  CICPSLPYSPVSSPQSSPRLPRRPTVESHHVSITGMQDCVQLNQYTLKDEIGKGSYGVVK
  LAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCIQPRGPIEQVYQEIAIL
  KKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTLKPLSEDQARFYFQDLIKGI
  EYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDALLSNTVGTPAFMAPESLS
  ETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIAEDLK
  DLITRMLDKNPESRIVVPEIKLHPWVTRHGAEPLPSEDENCTLVEVTEEEVENSVKHIPS
  LATVILVKTMIRKRSFGNPFEGSRREERSLSAPGNLLTKKPTRECESLSELKEARQRRQP
  PGHRPAPRGGGGSALVRGSPCVESCWAPAPGSPARMHPLRPEEAMEPE

• Sequence length: 588

Associated diseases

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Clear cell carcinoma of kidney	Benign	rs891780	RCV005903667
Thyroid cancer, nonmedullary, 1	Benign	rs891780	RCV005903668
Uterine corpus endometrial carcinoma	Benign	rs891780	RCV005903669

Associations from Text Mining
Disease Name	Relationship Type	References
Abidi X linked mental retardation syndrome	Associate	28737528
AIDS Associated Nephropathy	Associate	37166584
Alopecia	Associate	35438341
Anxiety	Associate	33082841
Bipolar Disorder	Associate	33082841
Breast Neoplasms	Associate	37661833
Carcinogenesis	Associate	34725334
Cerebral Infarction	Associate	22662160
Cholangiocarcinoma	Associate	38082327
Cystic Fibrosis	Associate	24859760
Diabetes Mellitus Type 2	Associate	29358691
Glioma	Associate	27012733, 40715243
Hearing Loss	Associate	35438341
Hearing Loss Noise Induced	Inhibit	35438341
Hypercalcemia	Associate	18249060
Hypertension	Associate	22662160
Hypoxia	Associate	37661833
Inflammation	Associate	24835252, 40076701
Lead Poisoning Nervous System	Associate	29133590
Leukemia Lymphoma Adult T Cell	Associate	18249060
Leukemia Promyelocytic Acute	Associate	34943872
Mandibular Nerve Injuries	Associate	37166584
Metabolic Diseases	Associate	34563205
Mitochondrial Diseases	Associate	38082327
Nasopharyngeal Carcinoma	Associate	34293937
Neoplasm Metastasis	Inhibit	38082327
Neoplasms	Associate	25394900, 28761044, 29133590, 34725334
Ovarian Neoplasms	Associate	28634229, 35309839
Prostatic Neoplasms	Associate	21098087, 25394900, 29431615
Schizophrenia Spectrum and Other Psychotic Disorders	Associate	28737528
Stomach Neoplasms	Associate	25756516
Tooth Loss	Stimulate	35438341
Uterine Cervical Neoplasms	Associate	31744495
Wounds and Injuries	Stimulate	35438341