Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs Other IDs
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	63827
Gene name Gene Name - the full gene name approved by the HGNC.	Brevican
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	BCAN
Synonyms (NCBI Gene) Gene synonyms aliases	BEHAB, CSPG7
Chromosome Chromosome number	1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	1q23.1
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a member of the lectican family of chondroitin sulfate proteoglycans that is specifically expressed in the central nervous system. This protein is developmentally regulated and may function in the formation of the brain extracellular mat

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miRTarBase ID	miRNA	Experiments	Reference
MIRT021697	hsa-miR-133a-3p	Microarray	21396852
MIRT489342	hsa-miR-3938	PAR-CLIP	20371350
MIRT489341	hsa-miR-4780	PAR-CLIP	20371350
MIRT489340	hsa-miR-6780b-3p	PAR-CLIP	20371350
MIRT489339	hsa-miR-2276-3p	PAR-CLIP	20371350
MIRT489338	hsa-miR-3148	PAR-CLIP	20371350
MIRT489336	hsa-miR-6124	PAR-CLIP	20371350
MIRT489337	hsa-miR-623	PAR-CLIP	20371350
MIRT489335	hsa-miR-204-5p	PAR-CLIP	20371350
MIRT489334	hsa-miR-211-5p	PAR-CLIP	20371350
MIRT489333	hsa-miR-3978	PAR-CLIP	20371350
MIRT489332	hsa-miR-4755-5p	PAR-CLIP	20371350
MIRT489331	hsa-miR-5006-3p	PAR-CLIP	20371350
MIRT489342	hsa-miR-3938	PAR-CLIP	20371350
MIRT529928	hsa-miR-4793-5p	PAR-CLIP	20371350
MIRT489341	hsa-miR-4780	PAR-CLIP	20371350
MIRT489340	hsa-miR-6780b-3p	PAR-CLIP	20371350
MIRT489339	hsa-miR-2276-3p	PAR-CLIP	20371350
MIRT489338	hsa-miR-3148	PAR-CLIP	20371350
MIRT489336	hsa-miR-6124	PAR-CLIP	20371350
MIRT489337	hsa-miR-623	PAR-CLIP	20371350
MIRT489335	hsa-miR-204-5p	PAR-CLIP	20371350
MIRT489334	hsa-miR-211-5p	PAR-CLIP	20371350
MIRT489333	hsa-miR-3978	PAR-CLIP	20371350
MIRT489332	hsa-miR-4755-5p	PAR-CLIP	20371350
MIRT489331	hsa-miR-5006-3p	PAR-CLIP	20371350
MIRT489342	hsa-miR-3938	PAR-CLIP	21572407
MIRT529928	hsa-miR-4793-5p	PAR-CLIP	21572407
MIRT489341	hsa-miR-4780	PAR-CLIP	21572407
MIRT489340	hsa-miR-6780b-3p	PAR-CLIP	21572407
MIRT489339	hsa-miR-2276-3p	PAR-CLIP	21572407
MIRT489338	hsa-miR-3148	PAR-CLIP	21572407
MIRT489336	hsa-miR-6124	PAR-CLIP	21572407
MIRT489337	hsa-miR-623	PAR-CLIP	21572407
MIRT489335	hsa-miR-204-5p	PAR-CLIP	21572407
MIRT489334	hsa-miR-211-5p	PAR-CLIP	21572407
MIRT489333	hsa-miR-3978	PAR-CLIP	21572407
MIRT489332	hsa-miR-4755-5p	PAR-CLIP	21572407
MIRT489331	hsa-miR-5006-3p	PAR-CLIP	21572407
MIRT489344	hsa-miR-548as-3p	PAR-CLIP	22012620
MIRT489342	hsa-miR-3938	PAR-CLIP	22012620
MIRT529928	hsa-miR-4793-5p	PAR-CLIP	22012620
MIRT489341	hsa-miR-4780	PAR-CLIP	22012620
MIRT489340	hsa-miR-6780b-3p	PAR-CLIP	22012620
MIRT489339	hsa-miR-2276-3p	PAR-CLIP	22012620
MIRT489338	hsa-miR-3148	PAR-CLIP	22012620
MIRT489336	hsa-miR-6124	PAR-CLIP	22012620
MIRT489337	hsa-miR-623	PAR-CLIP	22012620
MIRT489335	hsa-miR-204-5p	PAR-CLIP	22012620
MIRT489334	hsa-miR-211-5p	PAR-CLIP	22012620
MIRT489333	hsa-miR-3978	PAR-CLIP	22012620
MIRT489332	hsa-miR-4755-5p	PAR-CLIP	22012620
MIRT489331	hsa-miR-5006-3p	PAR-CLIP	22012620
MIRT489344	hsa-miR-548as-3p	PAR-CLIP	23592263
MIRT489342	hsa-miR-3938	PAR-CLIP	23592263
MIRT489341	hsa-miR-4780	PAR-CLIP	23592263
MIRT489340	hsa-miR-6780b-3p	PAR-CLIP	23592263
MIRT489339	hsa-miR-2276-3p	PAR-CLIP	23592263
MIRT489338	hsa-miR-3148	PAR-CLIP	23592263
MIRT489336	hsa-miR-6124	PAR-CLIP	23592263
MIRT489337	hsa-miR-623	PAR-CLIP	23592263
MIRT489335	hsa-miR-204-5p	PAR-CLIP	23592263
MIRT489334	hsa-miR-211-5p	PAR-CLIP	23592263
MIRT489333	hsa-miR-3978	PAR-CLIP	23592263
MIRT489332	hsa-miR-4755-5p	PAR-CLIP	23592263
MIRT489331	hsa-miR-5006-3p	PAR-CLIP	23592263
MIRT489335	hsa-miR-204-5p	PAR-CLIP	27292025
MIRT489334	hsa-miR-211-5p	PAR-CLIP	27292025
MIRT489339	hsa-miR-2276-3p	PAR-CLIP	27292025
MIRT489338	hsa-miR-3148	PAR-CLIP	27292025
MIRT489342	hsa-miR-3938	PAR-CLIP	27292025
MIRT489333	hsa-miR-3978	PAR-CLIP	27292025
MIRT489332	hsa-miR-4755-5p	PAR-CLIP	27292025
MIRT489341	hsa-miR-4780	PAR-CLIP	27292025
MIRT529928	hsa-miR-4793-5p	PAR-CLIP	27292025
MIRT489331	hsa-miR-5006-3p	PAR-CLIP	27292025
MIRT489336	hsa-miR-6124	PAR-CLIP	27292025
MIRT489337	hsa-miR-623	PAR-CLIP	27292025
MIRT489340	hsa-miR-6780b-3p	PAR-CLIP	27292025
MIRT489342	hsa-miR-3938	PAR-CLIP	20371350
MIRT489341	hsa-miR-4780	PAR-CLIP	20371350
MIRT489340	hsa-miR-6780b-3p	PAR-CLIP	20371350
MIRT489339	hsa-miR-2276-3p	PAR-CLIP	20371350
MIRT489338	hsa-miR-3148	PAR-CLIP	20371350
MIRT489336	hsa-miR-6124	PAR-CLIP	20371350
MIRT489337	hsa-miR-623	PAR-CLIP	20371350
MIRT489335	hsa-miR-204-5p	PAR-CLIP	20371350
MIRT489334	hsa-miR-211-5p	PAR-CLIP	20371350
MIRT489333	hsa-miR-3978	PAR-CLIP	20371350
MIRT489332	hsa-miR-4755-5p	PAR-CLIP	20371350
MIRT489331	hsa-miR-5006-3p	PAR-CLIP	20371350
MIRT489342	hsa-miR-3938	PAR-CLIP	20371350
MIRT529928	hsa-miR-4793-5p	PAR-CLIP	20371350
MIRT489341	hsa-miR-4780	PAR-CLIP	20371350
MIRT489340	hsa-miR-6780b-3p	PAR-CLIP	20371350
MIRT489339	hsa-miR-2276-3p	PAR-CLIP	20371350
MIRT489338	hsa-miR-3148	PAR-CLIP	20371350
MIRT489336	hsa-miR-6124	PAR-CLIP	20371350
MIRT489337	hsa-miR-623	PAR-CLIP	20371350
MIRT489335	hsa-miR-204-5p	PAR-CLIP	20371350
MIRT489334	hsa-miR-211-5p	PAR-CLIP	20371350
MIRT489333	hsa-miR-3978	PAR-CLIP	20371350
MIRT489332	hsa-miR-4755-5p	PAR-CLIP	20371350
MIRT489331	hsa-miR-5006-3p	PAR-CLIP	20371350
MIRT489342	hsa-miR-3938	PAR-CLIP	21572407
MIRT529928	hsa-miR-4793-5p	PAR-CLIP	21572407
MIRT489341	hsa-miR-4780	PAR-CLIP	21572407
MIRT489340	hsa-miR-6780b-3p	PAR-CLIP	21572407
MIRT489339	hsa-miR-2276-3p	PAR-CLIP	21572407
MIRT489338	hsa-miR-3148	PAR-CLIP	21572407
MIRT489336	hsa-miR-6124	PAR-CLIP	21572407
MIRT489337	hsa-miR-623	PAR-CLIP	21572407
MIRT489335	hsa-miR-204-5p	PAR-CLIP	21572407
MIRT489334	hsa-miR-211-5p	PAR-CLIP	21572407
MIRT489333	hsa-miR-3978	PAR-CLIP	21572407
MIRT489332	hsa-miR-4755-5p	PAR-CLIP	21572407
MIRT489331	hsa-miR-5006-3p	PAR-CLIP	21572407
MIRT489344	hsa-miR-548as-3p	PAR-CLIP	22012620
MIRT489342	hsa-miR-3938	PAR-CLIP	22012620
MIRT529928	hsa-miR-4793-5p	PAR-CLIP	22012620
MIRT489341	hsa-miR-4780	PAR-CLIP	22012620
MIRT489340	hsa-miR-6780b-3p	PAR-CLIP	22012620
MIRT489339	hsa-miR-2276-3p	PAR-CLIP	22012620
MIRT489338	hsa-miR-3148	PAR-CLIP	22012620
MIRT489336	hsa-miR-6124	PAR-CLIP	22012620
MIRT489337	hsa-miR-623	PAR-CLIP	22012620
MIRT489335	hsa-miR-204-5p	PAR-CLIP	22012620
MIRT489334	hsa-miR-211-5p	PAR-CLIP	22012620
MIRT489333	hsa-miR-3978	PAR-CLIP	22012620
MIRT489332	hsa-miR-4755-5p	PAR-CLIP	22012620
MIRT489331	hsa-miR-5006-3p	PAR-CLIP	22012620
MIRT489344	hsa-miR-548as-3p	PAR-CLIP	23592263
MIRT489342	hsa-miR-3938	PAR-CLIP	23592263
MIRT489341	hsa-miR-4780	PAR-CLIP	23592263
MIRT489340	hsa-miR-6780b-3p	PAR-CLIP	23592263
MIRT489339	hsa-miR-2276-3p	PAR-CLIP	23592263
MIRT489338	hsa-miR-3148	PAR-CLIP	23592263
MIRT489336	hsa-miR-6124	PAR-CLIP	23592263
MIRT489337	hsa-miR-623	PAR-CLIP	23592263
MIRT489335	hsa-miR-204-5p	PAR-CLIP	23592263
MIRT489334	hsa-miR-211-5p	PAR-CLIP	23592263
MIRT489333	hsa-miR-3978	PAR-CLIP	23592263
MIRT489332	hsa-miR-4755-5p	PAR-CLIP	23592263
MIRT489331	hsa-miR-5006-3p	PAR-CLIP	23592263
MIRT817304	hsa-miR-3151	CLIP-seq
MIRT817305	hsa-miR-3194-3p	CLIP-seq
MIRT817306	hsa-miR-4283	CLIP-seq
MIRT817307	hsa-miR-4447	CLIP-seq
MIRT817308	hsa-miR-4472	CLIP-seq
MIRT817309	hsa-miR-4489	CLIP-seq
MIRT817310	hsa-miR-4492	CLIP-seq
MIRT817311	hsa-miR-4498	CLIP-seq
MIRT817312	hsa-miR-491-5p	CLIP-seq
MIRT817313	hsa-miR-576-3p	CLIP-seq
MIRT817314	hsa-miR-762	CLIP-seq
MIRT2384745	hsa-miR-4768-3p	CLIP-seq
MIRT2444664	hsa-miR-3622a-3p	CLIP-seq
MIRT2444665	hsa-miR-3622b-3p	CLIP-seq
MIRT2444666	hsa-miR-3690	CLIP-seq
MIRT2444667	hsa-miR-378	CLIP-seq
MIRT2444668	hsa-miR-378b	CLIP-seq
MIRT2444669	hsa-miR-378c	CLIP-seq
MIRT2444670	hsa-miR-378d	CLIP-seq
MIRT2444671	hsa-miR-378e	CLIP-seq
MIRT2444672	hsa-miR-378f	CLIP-seq
MIRT2444673	hsa-miR-378h	CLIP-seq
MIRT2444674	hsa-miR-378i	CLIP-seq
MIRT2444675	hsa-miR-3925-3p	CLIP-seq
MIRT2444676	hsa-miR-422a	CLIP-seq
MIRT2444677	hsa-miR-4712-5p	CLIP-seq
MIRT2444678	hsa-miR-508-5p	CLIP-seq
MIRT2444679	hsa-miR-619	CLIP-seq
MIRT2444680	hsa-miR-770-5p	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0001501	Process	Skeletal system development	IBA	21873635
GO:0005515	Function	Protein binding	IPI	32814053
GO:0005540	Function	Hyaluronic acid binding	IEA
GO:0005576	Component	Extracellular region	TAS
GO:0005796	Component	Golgi lumen	TAS
GO:0007155	Process	Cell adhesion	IEA
GO:0007417	Process	Central nervous system development	IBA	21873635
GO:0021766	Process	Hippocampus development	IEA
GO:0030198	Process	Extracellular matrix organization	TAS
GO:0030206	Process	Chondroitin sulfate biosynthetic process	TAS
GO:0030207	Process	Chondroitin sulfate catabolic process	TAS
GO:0030208	Process	Dermatan sulfate biosynthetic process	TAS
GO:0030246	Function	Carbohydrate binding	IEA
GO:0031012	Component	Extracellular matrix	IBA	21873635
GO:0031225	Component	Anchored component of membrane	IEA
GO:0043202	Component	Lysosomal lumen	TAS
GO:0060074	Process	Synapse maturation	IEA
GO:0098978	Component	Glutamatergic synapse	IEA

MIM	HGNC	e!Ensembl
600347	23059	ENSG00000132692

Protein

UniProt ID

Q96GW7

Protein name

Brevican core protein (Brain-enriched hyaluronan-binding protein) (BEHAB) (Chondroitin sulfate proteoglycan 7)

Protein function

May play a role in the terminally differentiating and the adult nervous system during postnatal development. Could stabilize interactions between hyaluronan (HA) and brain proteoglycans.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF07686	V-set	41 → 155	Immunoglobulin V-set domain	Domain
PF00193	Xlink	157 → 251	Extracellular link domain	Domain
PF00193	Xlink	258 → 353	Extracellular link domain	Domain
PF00008	EGF	650 → 680	EGF-like domain	Domain
PF00059	Lectin_C	705 → 810	Lectin C-type domain	Domain
PF00084	Sushi	815 → 871	Sushi repeat (SCR repeat)	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed in the retina, specifically in the inner nuclear layer, inner plexiform layer and ganglion cell layer (at protein level) (PubMed:29777959). Detected in cerebrospinal fluid (at protein level) (PubMed:25326458). Detected in uri

Sequence

MAQLFLPLLAALVLAQAPAALADVLEGDSSEDRAFRVRIAGDAPLQGVLGGALTIPCHVH
YLRPPPSRRAVLGSPRVKWTFLSRGREAEVLVARGVRVKVNEAYRFRVALPAYPASLTDV
SLALSELRPNDSGIYRCEVQHGIDDSSDAVEVKVKGVVFLYREGSARYAFSFSGAQEACA
RIGAHIATPEQLYAAYLGGYEQCDAGWLSDQTVRYPIQTPREACYGDMDGFPGVRNYGVV
DPDDLYDVYCYAEDLNGELFLGDPPEKLTLEEARAYCQERGAEIATTGQLYAAWDGGLDH
CSPGWLADGSVRYPIVTPSQRCGGGLPGVKTLFLFPNQTGFPNKHSRFNVYCFRDSAQPS
AIPEASNPASNPASDGLEAIVTVTETLEELQLPQEATESESRGAIYSIPIMEDGGGGSST
PEDPAEAPRTLLEFETQSMVPPTGFSEEEGKALEEEEKYEDEEEKEEEEEEEEVEDEALW
AWPSELSSPGPEASLPTEPAAQEESLSQAPARAVLQPGASPLPDGESEASRPPRVHGPPT
ETLPTPRERNLASPSPSTLVEAREVGEATGGPELSGVPRGESEETGSSEGAPSLLPATRA
PEGTRELEAPSEDNSGRTAPAGTSVQAQPVLPTDSASRGGVAVVPASGDCVPSPCHNGGT
CLEEEEGVRCLCLPGYGGDLCDVGLRFCNPGWDAFQGACYKHFSTRRSWEEAETQCRMYG
AHLASISTPEEQDFINNRYREYQWIGLNDRTIEGDFLWSDGVPLLYENWNPGQPDSYFLS
GENCVVMVWHDQGQWSDVPCNYHLSYTCKMGLVSCGPPPELPLAQVFGRPRLRYEVDTVL
RYRCREGLAQRNLPLIRCQENGRWEAPQISCVPRRPARALHPEEDPEGRQGRLLGRWKAL
LIPPSSPMPGP

Sequence length

911

Interactions

View interactions

BCAN (brevican)