Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
483
Gene name Gene Name - the full gene name approved by the HGNC.
ATPase Na+/K+ transporting subunit beta 3
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
ATP1B3
Synonyms (NCBI Gene) Gene synonyms aliases
ATPB-3, CD298
Chromosome Chromosome number
3
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
3q23
Summary Summary of gene provided in NCBI Entrez Gene.
The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemica
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT025733 hsa-miR-7-5p Microarray 19073608
MIRT048487 hsa-miR-100-5p CLASH 23622248
MIRT045107 hsa-miR-186-5p CLASH 23622248
MIRT036767 hsa-miR-760 CLASH 23622248
MIRT705414 hsa-miR-1197 HITS-CLIP 23313552
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0001671 Function ATPase activator activity IBA 21873635
GO:0001671 Function ATPase activator activity IDA 10636900, 19542013
GO:0005515 Function Protein binding IPI 32296183
GO:0005886 Component Plasma membrane IDA 18522992
GO:0005886 Component Plasma membrane TAS
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
601867 806 ENSG00000069849
Protein
UniProt ID P54709
Protein name Sodium/potassium-transporting ATPase subunit beta-3 (Sodium/potassium-dependent ATPase subunit beta-3) (ATPB-3) (CD antigen CD298)
Protein function This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00287 Na_K-ATPase 6 273 Sodium / potassium ATPase beta chain Family
Sequence
Sequence length 279
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Unknown
Disease term Disease name Evidence References Source
Coronary artery disease Coronary artery disease GWAS
Associations from Text Mining
Disease Name Relationship Type References
Adenocarcinoma of Lung Associate 38608841
Breast Neoplasms Associate 31972357, 36232400
Carcinoma Associate 35265720
Carcinoma Hepatocellular Stimulate 33868261
Colorectal Neoplasms Associate 38608841
Fibrosarcoma Associate 35265720
Neoplasm Metastasis Associate 35265720
Squamous Cell Carcinoma of Head and Neck Associate 35655921