Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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223
|
Gene name
Gene Name - the full gene name approved by the HGNC.
|
Aldehyde dehydrogenase 9 family member A1 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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ALDH9A1 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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ALDH4, ALDH7, ALDH9, E3, TMABA-DH, TMABADH, TMABALDH |
Chromosome
Chromosome number
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1 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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1q24.1 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This protein belongs to the aldehyde dehydrogenase family of proteins. It has a high activity for oxidation of gamma-aminobutyraldehyde and other amino aldehydes. The enzyme catalyzes the dehydrogenation of gamma-aminobutyraldehyde to gamma-aminobutyric a |
UniProt ID |
P49189
|
Protein name |
4-trimethylaminobutyraldehyde dehydrogenase (TMABA-DH) (TMABALDH) (EC 1.2.1.47) (Aldehyde dehydrogenase E3 isozyme) (Aldehyde dehydrogenase family 9 member A1) (EC 1.2.1.3) (Formaldehyde dehydrogenase) (EC 1.2.1.46) (Gamma-aminobutyraldehyde dehydrogenase |
Protein function |
Converts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine with high efficiency (in vitro). Can catalyze the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction, but with low effi |
PDB |
6QAK
,
6QAO
,
6QAP
,
6VR6
,
6VWF
|
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF00171
|
Aldedh |
21 → 483 |
Aldehyde dehydrogenase family |
Family |
|
Tissue specificity |
TISSUE SPECIFICITY: Detected in brain (at protein level) (PubMed:8645224). High expression in adult liver, skeletal muscle, and kidney. Low levels in heart, pancreas, lung and brain (PubMed:8786138). Expressed in all regions of the brain. Expression level |
Sequence |
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Sequence length |
494 |
Interactions |
View interactions
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