ALDH3A2 (aldehyde dehydrogenase 3 family member A2)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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224 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Aldehyde dehydrogenase 3 family member A2 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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ALDH3A2 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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ALDH10, FALDH, SLS |
Disease Acronyms (UniProt)
Disease acronyms from UniProt database
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SLS |
Chromosome
Chromosome number
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17 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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17p11.2 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This gene product catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acid. Mutation |
SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | P51648 | ||||||||||
Protein name | Aldehyde dehydrogenase family 3 member A2 (EC 1.2.1.3) (EC 1.2.1.94) (Aldehyde dehydrogenase 10) (Fatty aldehyde dehydrogenase) (Microsomal aldehyde dehydrogenase) | ||||||||||
Protein function | Catalyzes the oxidation of medium and long chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length (PubMed:18035827, PubMed:18182499, PubMed:22633490, PubM | ||||||||||
PDB | 4QGK | ||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Detected in liver (at protein level). {ECO:0000269|PubMed:9133646}. | ||||||||||
Sequence | |||||||||||
Sequence length | 485 | ||||||||||
Interactions | View interactions |