Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
79602
|
Gene name
Gene Name - the full gene name approved by the HGNC.
|
Adiponectin receptor 2 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
|
ADIPOR2 |
Synonyms (NCBI Gene)
Gene synonyms aliases
|
ACDCR2, PAQR2 |
Chromosome
Chromosome number
|
12 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
12p13.33 |
Summary
Summary of gene provided in NCBI Entrez Gene.
|
The adiponectin receptors, ADIPOR1 (MIM 607945) and ADIPOR2, serve as receptors for globular and full-length adiponectin (MIM 605441) and mediate increased AMPK (see MIM 602739) and PPAR-alpha (PPARA; MIM 170998) ligand activities, as well as fatty acid o |
UniProt ID |
Q86V24
|
Protein name |
Adiponectin receptor protein 2 (Progestin and adipoQ receptor family member 2) (Progestin and adipoQ receptor family member II) |
Protein function |
Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism (PubMed:12802337, PubMed:25855295). Required for normal body fat and glucose homeostasis. ADIPOQ-binding activates a signaling cascade t |
PDB |
5LWY
,
5LX9
,
5LXA
,
6KS1
,
6YX9
,
6YXD
,
6YXF
,
6YXG
|
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF03006
|
HlyIII |
140 → 363 |
Haemolysin-III related |
Family |
|
Tissue specificity |
TISSUE SPECIFICITY: Ubiquitous (PubMed:16044242). Highly expressed in skeletal muscle, liver and placenta (PubMed:12802337). Weakly expressed in brain, heart, colon, spleen, kidney, thymus, small intestine, peripheral blood leukocytes and lung (PubMed:128 |
Sequence |
|
Sequence length |
386 |
Interactions |
View interactions
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