ADH1A (alcohol dehydrogenase 1A (class I), alpha polypeptide)

Gene
Gene SNPs Transcription factors Other IDs
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
124
Gene name Gene Name - the full gene name approved by the HGNC.
Alcohol dehydrogenase 1A (class I), alpha polypeptide
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
ADH1A
Synonyms (NCBI Gene) Gene synonyms aliases
ADH1
Chromosome Chromosome number
4
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
4q23
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a member of the alcohol dehydrogenase family. The encoded protein is the alpha subunit of class I alcohol dehydrogenase, which consists of several homo- and heterodimers of alpha, beta and gamma subunits. Alcohol dehydrogenases catalyze
miRNA miRNA information provided by mirtarbase database.
Gene SNPs Transcription factors Other IDs
Show/Hide all(4)
miRTarBase ID miRNA Experiments Reference
MIRT021722 hsa-miR-132-3p Microarray 17612493
MIRT768615 hsa-miR-4468 CLIP-seq
MIRT768616 hsa-miR-4677-3p CLIP-seq
MIRT768617 hsa-miR-4679 CLIP-seq
Transcription factors
Gene SNPs Transcription factors Other IDs
Show/Hide all(1)
Transcription factor Regulation Reference
GATA2 Activation 16153155
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene SNPs Transcription factors Other IDs
Show/Hide all(16)
GO ID Ontology Definition Evidence Reference
GO:0004024 Function Alcohol dehydrogenase activity, zinc-dependent IBA 21873635
GO:0004024 Function Alcohol dehydrogenase activity, zinc-dependent IDA 9982
GO:0004745 Function Retinol dehydrogenase activity IBA 21873635
GO:0005515 Function Protein binding IPI 16153155
GO:0005654 Component Nucleoplasm IDA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene SNPs Transcription factors Other IDs
MIM HGNC e!Ensembl
103700 249 ENSG00000187758
Protein
Gene SNPs Transcription factors Other IDs
UniProt ID P07327
Protein name Alcohol dehydrogenase 1A (EC 1.1.1.1) (Alcohol dehydrogenase subunit alpha)
Protein function Alcohol dehydrogenase (PubMed:2738060). Oxidizes primary as well as secondary alcohols. Ethanol is a very poor substrate (PubMed:2738060).
PDB 1HSO , 1U3T
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF08240 ADH_N 34 → 161 Alcohol dehydrogenase GroES-like domain Domain
PF00107 ADH_zinc_N 203 → 339 Zinc-binding dehydrogenase Family
Sequence
Sequence length 375
Interactions View interactions