ADCY6 (adenylate cyclase 6)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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112 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Adenylate cyclase 6 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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ADCY6 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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AC6, LCCS8 |
Disease Acronyms (UniProt)
Disease acronyms from UniProt database
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LCCS8 |
Chromosome
Chromosome number
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12 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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12q13.12 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the adenylyl cyclase family of proteins, which are required for the synthesis of cyclic AMP. All members of this family have an intracellular N-terminus, a tandem repeat of six transmembrane domains separated by a cytoplasmic |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||||||||||||||||||||||||||
UniProt ID | O43306 | |||||||||||||||||||||||||
Protein name | Adenylate cyclase type 6 (EC 4.6.1.1) (ATP pyrophosphate-lyase 6) (Adenylate cyclase type VI) (Adenylyl cyclase 6) (Ca(2+)-inhibitable adenylyl cyclase) | |||||||||||||||||||||||||
Protein function | Catalyzes the formation of the signaling molecule cAMP downstream of G protein-coupled receptors (PubMed:17110384, PubMed:17916776). Functions in signaling cascades downstream of beta-adrenergic receptors in the heart and in vascular smooth musc | |||||||||||||||||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Detected in peripheral blood mononuclear leukocytes (at protein level) (PubMed:17916776). Detected in thyroid (PubMed:10978539). {ECO:0000269|PubMed:10978539}. | |||||||||||||||||||||||||
Sequence | ||||||||||||||||||||||||||
Sequence length | 1168 | |||||||||||||||||||||||||
Interactions | View interactions |
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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