ACTB (actin beta)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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60 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Actin beta |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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ACTB |
Synonyms (NCBI Gene)
Gene synonyms aliases
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BKRNS, BNS, BRWS1, CSMH, DDS1, PS1TP5BP1, THC8 |
Disease Acronyms (UniProt)
Disease acronyms from UniProt database
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BNS, BRWS1, CSMH, DDS1, THC8 |
Chromosome
Chromosome number
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7 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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7p22.1 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a major constituent of the contractile apparatus and |
SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | P60709 | ||||||||||
Protein name | Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed] | ||||||||||
Protein function | Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells (PubMed:25255767, PubMed:29581253). Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both | ||||||||||
PDB | 3BYH , 3D2U , 3J82 , 3LUE , 6ANU , 6ICT , 6ICV , 6LTJ , 6MBJ , 6MBK , 6MBL , 6NBW , 6OX0 , 6OX1 , 6OX2 , 6OX3 , 6OX4 , 6OX5 , 6V62 , 6V63 , 6WK1 , 6WK2 , 7AS4 , 7P1H , 7QJ6 , 7QJ9 , 7VDV , 7W28 , 7W29 , 7Y8R , 7ZTC , 7ZTD , 8COG , 8DNH , 8IB8 , 8OI8 , 8OID , 8QR1 , 8RTT , 8RTY , 8RU2 , 8RX1 , 8UAU , 8VRD , 8VRJ , 8VRK , 8X15 , 8X19 , 8X1C , 8XVG , 8XVT | ||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 375 | ||||||||||
Interactions | View interactions |
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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