ACSL3 (acyl-CoA synthetase long chain family member 3)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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2181 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Acyl-CoA synthetase long chain family member 3 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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ACSL3 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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ACS3, FACL3, LACS 3, LACS3, PRO2194 |
Chromosome
Chromosome number
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2 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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2q36.1 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | O95573 | ||||||||||
Protein name | Fatty acid CoA ligase Acsl3 (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain acyl-CoA synthetase 3) (LACS 3) (Long-chain-fatty-acid--CoA ligase 3) (EC 6.2.1.3) (Medium-chain acyl-CoA ligase Acsl3) (EC 6.2.1.2) | ||||||||||
Protein function | Acyl-CoA synthetases (ACSL) activates long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:22633490). Required for the incorporation of fatty acids into phosphatidylcholine, the major phospholi | ||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 720 | ||||||||||
Interactions | View interactions |
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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