ACOX1 (acyl-CoA oxidase 1)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 51 |
| Gene name | Acyl-CoA oxidase 1 |
| Gene symbol | ACOX1 |
| Synonyms (NCBI Gene) |
ACOXAOXMITCHPALMCOXSCOX
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| Chromosome | 17 |
| Chromosome location | 17q25.1 |
| Summary | The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Def |
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SNPs
SNP information provided by dbSNP.
9
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miRNA
miRNA information provided by mirtarbase database.
806
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Transcription factors
Transcription factors information provided by TRRUST V2 database.
1
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
56
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q15067 | ||||||||||||||||||||
| Protein name | Peroxisomal acyl-coenzyme A oxidase 1 (AOX) (EC 1.3.3.6) (Palmitoyl-CoA oxidase) (Peroxisomal fatty acyl-CoA oxidase) (Straight-chain acyl-CoA oxidase) (SCOX) [Cleaved into: Peroxisomal acyl-CoA oxidase 1, A chain; Peroxisomal acyl-CoA oxidase 1, B chain; | ||||||||||||||||||||
| Protein function | Involved in the initial and rate-limiting step of peroxisomal beta-oxidation of straight-chain saturated and unsaturated very-long-chain fatty acids (PubMed:15060085, PubMed:17458872, PubMed:17603022, PubMed:32169171, PubMed:33234382, PubMed:787 | ||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Widely expressed with highest levels of isoform 1 and isoform 2 detected in testis. Isoform 1 is expressed at higher levels than isoform 2 in liver and kidney while isoform 2 levels are higher in brain, lung, muscle, white adipose tiss | ||||||||||||||||||||
| Sequence |
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| Sequence length | 660 | ||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||