ABCC5 (ATP binding cassette subfamily C member 5)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 10057 |
| Gene name | ATP binding cassette subfamily C member 5 |
| Gene symbol | ABCC5 |
| Synonyms (NCBI Gene) |
ABC33EST277145MOAT-CMOATCMRP5SMRPpABC11
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| Chromosome | 3 |
| Chromosome location | 3q27.1 |
| Summary | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, M |
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miRNA
miRNA information provided by mirtarbase database.
679
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
53
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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O15440 | |||||||||||||||||||||||||
| Protein name | ATP-binding cassette sub-family C member 5 (EC 7.6.2.-) (EC 7.6.2.2) (Multi-specific organic anion transporter C) (MOAT-C) (Multidrug resistance-associated protein 5) (SMRP) (pABC11) | |||||||||||||||||||||||||
| Protein function | ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes physiological compounds, and xenobiotics from cells. Mediates ATP-dependent transport of endogenous metabolites such as cAMP and cGMP, folic acid and N-lac | |||||||||||||||||||||||||
| PDB | 8KCI , 8WI2 , 8WI3 , 8WI4 , 8WI5 | |||||||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: [Isoform 3]: Predominant isoform in retinal pigment epithelium, bladder, and stomach. {ECO:0000269|PubMed:17521428}.; TISSUE SPECIFICITY: Ubiquitously expressed, but levels in brain and muscle are especially high (PubMed:10438534, PubM | |||||||||||||||||||||||||
| Sequence | ||||||||||||||||||||||||||
| Sequence length | 1437 | |||||||||||||||||||||||||
| Interactions | View interactions | |||||||||||||||||||||||||
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
3
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