ABCC5 (ATP binding cassette subfamily C member 5)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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10057 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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ATP binding cassette subfamily C member 5 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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ABCC5 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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ABC33, EST277145, MOAT-C, MOATC, MRP5, SMRP, pABC11 |
Chromosome
Chromosome number
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3 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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3q27.1 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, M |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||||||||||||||||||||||||||
UniProt ID | O15440 | |||||||||||||||||||||||||
Protein name | ATP-binding cassette sub-family C member 5 (EC 7.6.2.-) (EC 7.6.2.2) (Multi-specific organic anion transporter C) (MOAT-C) (Multidrug resistance-associated protein 5) (SMRP) (pABC11) | |||||||||||||||||||||||||
Protein function | ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes physiological compounds, and xenobiotics from cells. Mediates ATP-dependent transport of endogenous metabolites such as cAMP and cGMP, folic acid and N-lac | |||||||||||||||||||||||||
PDB | 8KCI , 8WI2 , 8WI3 , 8WI4 , 8WI5 | |||||||||||||||||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: [Isoform 3]: Predominant isoform in retinal pigment epithelium, bladder, and stomach. {ECO:0000269|PubMed:17521428}.; TISSUE SPECIFICITY: Ubiquitously expressed, but levels in brain and muscle are especially high (PubMed:10438534, PubM | |||||||||||||||||||||||||
Sequence | ||||||||||||||||||||||||||
Sequence length | 1437 | |||||||||||||||||||||||||
Interactions | View interactions |
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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