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UBB (ubiquitin B)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
7314
Gene nameGene Name - the full gene name approved by the HGNC.
Ubiquitin B
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
UBB
SynonymsGene synonyms aliases
HEL-S-50
ChromosomeChromosome number
17
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
17p11.2
SummarySummary of gene provided in NCBI Entrez Gene.
This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene e
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT029681 hsa-miR-26b-5p Microarray 19088304
MIRT048633 hsa-miR-99a-5p CLASH 23622248
MIRT048512 hsa-miR-100-5p CLASH 23622248
MIRT047262 hsa-miR-181b-5p CLASH 23622248
MIRT040746 hsa-miR-18a-3p CLASH 23622248
Transcription factors
Transcription factor Regulation Reference
HSF1 Unknown 20692357
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000122 Process Negative regulation of transcription by RNA polymerase II TAS
GO:0000187 Process Activation of MAPK activity TAS
GO:0000209 Process Protein polyubiquitination TAS
GO:0000715 Process Nucleotide-excision repair, DNA damage recognition TAS
GO:0000717 Process Nucleotide-excision repair, DNA duplex unwinding TAS
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID P0CG47
Protein name Polyubiquitin-B [Cleaved into: Ubiquitin]
Protein function [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys re
PDB 2KHW , 2MBB , 2MRO , 2MSG , 2N13 , 4UEL , 4UF6 , 4WHV , 4WLR , 4WUR , 4XOF , 4ZFR , 4ZFT , 4ZPZ , 4ZUX , 5BNB , 5CAW , 5CRA , 5CVM , 5CVN , 5CVO , 5D0K , 5D0M , 5DFL , 5DK8 , 5E6J , 5EDV , 5EMZ , 5EYA , 5GJQ , 5GO7 , 5GO8 , 5GOB , 5GOC , 5GOD , 5GOG , 5GOH , 5GOI , 5GOJ , 5GOK , 5H7S , 5IBK , 5IFR , 5JBY , 5JG6 , 5JP3 , 5JTJ , 5JTV , 5K9P , 5KGF , 5KHY
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00240 ubiquitin
3 74
Ubiquitin family
Domain
PF00240 ubiquitin
79 150
Ubiquitin family
Domain
PF00240 ubiquitin
155 226
Ubiquitin family
Domain
Sequence
Sequence length 229
Interactions View interactions

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