GO ID |
Ontology |
Definition |
Evidence |
Reference |
GO:0000139 |
Component |
Golgi membrane |
TAS |
|
GO:0002224 |
Process |
Toll-like receptor signaling pathway |
IBA |
21873635 |
GO:0002224 |
Process |
Toll-like receptor signaling pathway |
TAS |
|
GO:0002237 |
Process |
Response to molecule of bacterial origin |
TAS |
15356140 |
GO:0002639 |
Process |
Positive regulation of immunoglobulin production |
IDA |
23857366 |
GO:0002755 |
Process |
MyD88-dependent toll-like receptor signaling pathway |
IEA |
|
GO:0004888 |
Function |
Transmembrane signaling receptor activity |
IEA |
|
GO:0005149 |
Function |
Interleukin-1 receptor binding |
IPI |
12925853 |
GO:0005576 |
Component |
Extracellular region |
NAS |
11130078 |
GO:0005737 |
Component |
Cytoplasm |
IDA |
19740627 |
GO:0005764 |
Component |
Lysosome |
ISS |
|
GO:0005768 |
Component |
Endosome |
ISS |
|
GO:0005783 |
Component |
Endoplasmic reticulum |
ISS |
|
GO:0005789 |
Component |
Endoplasmic reticulum membrane |
TAS |
|
GO:0005886 |
Component |
Plasma membrane |
IBA |
21873635 |
GO:0005886 |
Component |
Plasma membrane |
IDA |
19740627 |
GO:0006954 |
Process |
Inflammatory response |
IEA |
|
GO:0006955 |
Process |
Immune response |
IBA |
21873635 |
GO:0007249 |
Process |
I-kappaB kinase/NF-kappaB signaling |
IBA |
21873635 |
GO:0007252 |
Process |
I-kappaB phosphorylation |
IDA |
19740627 |
GO:0010008 |
Component |
Endosome membrane |
TAS |
|
GO:0010628 |
Process |
Positive regulation of gene expression |
IDA |
24409285 |
GO:0016021 |
Component |
Integral component of membrane |
IEA |
|
GO:0016323 |
Component |
Basolateral plasma membrane |
IDA |
17128265 |
GO:0016324 |
Component |
Apical plasma membrane |
IDA |
17128265 |
GO:0030277 |
Process |
Maintenance of gastrointestinal epithelium |
ISS |
|
GO:0030890 |
Process |
Positive regulation of B cell proliferation |
IDA |
23857366 |
GO:0032009 |
Component |
Early phagosome |
ISS |
|
GO:0032088 |
Process |
Negative regulation of NF-kappaB transcription factor activity |
IDA |
17128265 |
GO:0032640 |
Process |
Tumor necrosis factor production |
IBA |
21873635 |
GO:0032640 |
Process |
Tumor necrosis factor production |
IDA |
23826189 |
GO:0032715 |
Process |
Negative regulation of interleukin-6 production |
ISS |
|
GO:0032717 |
Process |
Negative regulation of interleukin-8 production |
IDA |
17128265 |
GO:0032722 |
Process |
Positive regulation of chemokine production |
IDA |
19740627 |
GO:0032725 |
Process |
Positive regulation of granulocyte macrophage colony-stimulating factor production |
IDA |
24409285 |
GO:0032727 |
Process |
Positive regulation of interferon-alpha production |
IDA |
16286015 |
GO:0032728 |
Process |
Positive regulation of interferon-beta production |
IDA |
16286015 |
GO:0032728 |
Process |
Positive regulation of interferon-beta production |
ISS |
|
GO:0032729 |
Process |
Positive regulation of interferon-gamma production |
IDA |
16286015 |
GO:0032733 |
Process |
Positive regulation of interleukin-10 production |
ISS |
|
GO:0032735 |
Process |
Positive regulation of interleukin-12 production |
ISS |
|
GO:0032741 |
Process |
Positive regulation of interleukin-18 production |
ISS |
|
GO:0032755 |
Process |
Positive regulation of interleukin-6 production |
IBA |
21873635 |
GO:0032755 |
Process |
Positive regulation of interleukin-6 production |
IDA |
19740627, 24409285 |
GO:0032757 |
Process |
Positive regulation of interleukin-8 production |
IDA |
17128265, 19740627, 24409285 |
GO:0032760 |
Process |
Positive regulation of tumor necrosis factor production |
ISS |
|
GO:0034122 |
Process |
Negative regulation of toll-like receptor signaling pathway |
IDA |
17128265 |
GO:0034123 |
Process |
Positive regulation of toll-like receptor signaling pathway |
IDA |
17128265 |
GO:0034162 |
Process |
Toll-like receptor 9 signaling pathway |
TAS |
|
GO:0034163 |
Process |
Regulation of toll-like receptor 9 signaling pathway |
IDA |
23857366 |
GO:0035197 |
Function |
SiRNA binding |
IMP |
15723075 |
GO:0036019 |
Component |
Endolysosome |
ISS |
|
GO:0036020 |
Component |
Endolysosome membrane |
TAS |
|
GO:0038187 |
Function |
Pattern recognition receptor activity |
IBA |
21873635 |
GO:0042742 |
Process |
Defense response to bacterium |
NAS |
11130078 |
GO:0042803 |
Function |
Protein homodimerization activity |
ISS |
|
GO:0043123 |
Process |
Positive regulation of I-kappaB kinase/NF-kappaB signaling |
IDA |
17128265 |
GO:0043410 |
Process |
Positive regulation of MAPK cascade |
IDA |
23857366 |
GO:0043507 |
Process |
Positive regulation of JUN kinase activity |
IDA |
17128265 |
GO:0045087 |
Process |
Innate immune response |
TAS |
15356140 |
GO:0045322 |
Function |
Unmethylated CpG binding |
ISS |
|
GO:0045577 |
Process |
Regulation of B cell differentiation |
IDA |
23857366 |
GO:0045944 |
Process |
Positive regulation of transcription by RNA polymerase II |
ISS |
|
GO:0046330 |
Process |
Positive regulation of JNK cascade |
IC |
17128265 |
GO:0050729 |
Process |
Positive regulation of inflammatory response |
IC |
19740627 |
GO:0050829 |
Process |
Defense response to Gram-negative bacterium |
IMP |
22427638 |
GO:0050871 |
Process |
Positive regulation of B cell activation |
IDA |
23857366 |
GO:0051092 |
Process |
Positive regulation of NF-kappaB transcription factor activity |
IBA |
21873635 |
GO:0051092 |
Process |
Positive regulation of NF-kappaB transcription factor activity |
IDA |
17128265 |
GO:0051607 |
Process |
Defense response to virus |
IBA |
21873635 |
GO:0051770 |
Process |
Positive regulation of nitric-oxide synthase biosynthetic process |
ISS |
|
GO:1901224 |
Process |
Positive regulation of NIK/NF-kappaB signaling |
IDA |
19740627 |
GO:1901895 |
Process |
Negative regulation of ATPase-coupled calcium transmembrane transporter activity |
IDA |
24610369 |