TJP1 (tight junction protein 1)

Gene

• Entrez ID: 7082
• Gene name: Tight junction protein 1
• Gene symbol: TJP1
• Synonyms: ZO-1
• Chromosome: 15
• Chromosome location: 15q13.1
• Summary: This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family of proteins, and acts as a tight junction adaptor protein that also regulates adherens junctions. Tight junctions regulate the movement of ions and macromolecules betwee

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT004341	hsa-miR-212-3p	Western blot	18162065
MIRT004341	hsa-miR-212-3p	Luciferase reporter assay	18162065
MIRT020884	hsa-miR-155-5p	Proteomics	18668040
MIRT051942	hsa-let-7b-5p	CLASH	23622248
MIRT050793	hsa-miR-17-5p	CLASH	23622248
MIRT042969	hsa-miR-324-3p	CLASH	23622248
MIRT039699	hsa-miR-615-3p	CLASH	23622248
MIRT438931	hsa-miR-105-5p	In situ hybridization, qRT-PCR, Luciferase reporter assay, Western blot, Microarray	24735924
MIRT0004379	hsa-miR-105-5p	In situ hybridization, qRT-PCR, Luciferase reporter assay, Western blot, Microarray	24735924
MIRT698475	hsa-miR-548ac	HITS-CLIP	23313552
MIRT698474	hsa-miR-548bb-3p	HITS-CLIP	23313552
MIRT698473	hsa-miR-548d-3p	HITS-CLIP	23313552
MIRT698472	hsa-miR-548h-3p	HITS-CLIP	23313552
MIRT698471	hsa-miR-548z	HITS-CLIP	23313552
MIRT698470	hsa-miR-548ae-3p	HITS-CLIP	23313552
MIRT698469	hsa-miR-548ah-3p	HITS-CLIP	23313552
MIRT698468	hsa-miR-548aj-3p	HITS-CLIP	23313552
MIRT698467	hsa-miR-548am-3p	HITS-CLIP	23313552
MIRT698466	hsa-miR-548aq-3p	HITS-CLIP	23313552
MIRT698465	hsa-miR-548j-3p	HITS-CLIP	23313552
MIRT698464	hsa-miR-548x-3p	HITS-CLIP	23313552
MIRT698463	hsa-miR-5582-3p	HITS-CLIP	23313552
MIRT698461	hsa-miR-5700	HITS-CLIP	23313552
MIRT698462	hsa-miR-4731-3p	HITS-CLIP	23313552
MIRT698460	hsa-miR-4801	HITS-CLIP	23313552
MIRT698459	hsa-miR-802	HITS-CLIP	23313552
MIRT553632	hsa-miR-411-3p	PAR-CLIP	21572407
MIRT553631	hsa-miR-379-3p	PAR-CLIP	21572407
MIRT553630	hsa-miR-107	PAR-CLIP	21572407
MIRT553629	hsa-miR-103a-3p	PAR-CLIP	21572407
MIRT553628	hsa-miR-548c-3p	PAR-CLIP	21572407
MIRT553627	hsa-miR-383-3p	PAR-CLIP	21572407
MIRT553626	hsa-miR-194-5p	PAR-CLIP	21572407
MIRT553625	hsa-miR-4799-5p	PAR-CLIP	21572407
MIRT732222	hsa-miR-212-5p	Luciferase reporter assay, Western blot	26692142
MIRT732222	hsa-miR-212-5p	Luciferase reporter assay, Western blot	26692142
MIRT735353	hsa-miR-4720-3p	Luciferase reporter assay, Western blotting, In situ hybridization	32314520
MIRT698475	hsa-miR-548ac	HITS-CLIP	23313552
MIRT698474	hsa-miR-548bb-3p	HITS-CLIP	23313552
MIRT698473	hsa-miR-548d-3p	HITS-CLIP	23313552
MIRT698472	hsa-miR-548h-3p	HITS-CLIP	23313552
MIRT698471	hsa-miR-548z	HITS-CLIP	23313552
MIRT698470	hsa-miR-548ae-3p	HITS-CLIP	23313552
MIRT698469	hsa-miR-548ah-3p	HITS-CLIP	23313552
MIRT698468	hsa-miR-548aj-3p	HITS-CLIP	23313552
MIRT698467	hsa-miR-548am-3p	HITS-CLIP	23313552
MIRT698466	hsa-miR-548aq-3p	HITS-CLIP	23313552
MIRT698465	hsa-miR-548j-3p	HITS-CLIP	23313552
MIRT698464	hsa-miR-548x-3p	HITS-CLIP	23313552
MIRT698463	hsa-miR-5582-3p	HITS-CLIP	23313552
MIRT698461	hsa-miR-5700	HITS-CLIP	23313552
MIRT698462	hsa-miR-4731-3p	HITS-CLIP	23313552
MIRT698460	hsa-miR-4801	HITS-CLIP	23313552
MIRT698459	hsa-miR-802	HITS-CLIP	23313552
MIRT553632	hsa-miR-411-3p	PAR-CLIP	21572407
MIRT553631	hsa-miR-379-3p	PAR-CLIP	21572407
MIRT553630	hsa-miR-107	PAR-CLIP	21572407
MIRT553629	hsa-miR-103a-3p	PAR-CLIP	21572407
MIRT553628	hsa-miR-548c-3p	PAR-CLIP	21572407
MIRT553627	hsa-miR-383-3p	PAR-CLIP	21572407
MIRT553626	hsa-miR-194-5p	PAR-CLIP	21572407
MIRT553625	hsa-miR-4799-5p	PAR-CLIP	21572407
MIRT755766	hsa-miR-23a-3p	Luciferase reporter assay, Western blotting, Microarray, qRT-PCR, Immunohistochemistry (IHC), in vitro cullelar assays, Immunofluorescence, ELISA	37904170
MIRT1425746	hsa-miR-101	CLIP-seq
MIRT1425747	hsa-miR-103b	CLIP-seq
MIRT1425748	hsa-miR-105	CLIP-seq
MIRT1425749	hsa-miR-1305	CLIP-seq
MIRT1425750	hsa-miR-137	CLIP-seq
MIRT1425751	hsa-miR-140-5p	CLIP-seq
MIRT1425752	hsa-miR-144	CLIP-seq
MIRT1425753	hsa-miR-145	CLIP-seq
MIRT1425754	hsa-miR-153	CLIP-seq
MIRT1425755	hsa-miR-191	CLIP-seq
MIRT1425756	hsa-miR-193a-3p	CLIP-seq
MIRT1425757	hsa-miR-193b	CLIP-seq
MIRT1425758	hsa-miR-200b	CLIP-seq
MIRT1425759	hsa-miR-200c	CLIP-seq
MIRT1425760	hsa-miR-23a	CLIP-seq
MIRT1425761	hsa-miR-23b	CLIP-seq
MIRT1425762	hsa-miR-23c	CLIP-seq
MIRT1425763	hsa-miR-3064-5p	CLIP-seq
MIRT1425764	hsa-miR-3133	CLIP-seq
MIRT1425765	hsa-miR-3200-3p	CLIP-seq
MIRT1425766	hsa-miR-337-3p	CLIP-seq
MIRT1425767	hsa-miR-3611	CLIP-seq
MIRT1425768	hsa-miR-361-5p	CLIP-seq
MIRT1425769	hsa-miR-3652	CLIP-seq
MIRT1425770	hsa-miR-3671	CLIP-seq
MIRT1425771	hsa-miR-369-3p	CLIP-seq
MIRT1425772	hsa-miR-374a	CLIP-seq
MIRT1425773	hsa-miR-374b	CLIP-seq
MIRT1425774	hsa-miR-376a	CLIP-seq
MIRT1425775	hsa-miR-376b	CLIP-seq
MIRT1425776	hsa-miR-3978	CLIP-seq
MIRT1425777	hsa-miR-4264	CLIP-seq
MIRT1425778	hsa-miR-4277	CLIP-seq
MIRT1425779	hsa-miR-429	CLIP-seq
MIRT1425780	hsa-miR-433	CLIP-seq
MIRT1425781	hsa-miR-4430	CLIP-seq
MIRT1425782	hsa-miR-4501	CLIP-seq
MIRT1425783	hsa-miR-4503	CLIP-seq
MIRT1425784	hsa-miR-4505	CLIP-seq
MIRT1425785	hsa-miR-4519	CLIP-seq
MIRT1425786	hsa-miR-4637	CLIP-seq
MIRT1425787	hsa-miR-4670-3p	CLIP-seq
MIRT1425788	hsa-miR-4676-5p	CLIP-seq
MIRT1425789	hsa-miR-4699-3p	CLIP-seq
MIRT1425790	hsa-miR-4760-5p	CLIP-seq
MIRT1425791	hsa-miR-4773	CLIP-seq
MIRT1425792	hsa-miR-4774-5p	CLIP-seq
MIRT1425793	hsa-miR-4777-5p	CLIP-seq
MIRT1425794	hsa-miR-495	CLIP-seq
MIRT1425795	hsa-miR-498	CLIP-seq
MIRT1425796	hsa-miR-501-3p	CLIP-seq
MIRT1425797	hsa-miR-502-3p	CLIP-seq
MIRT1425798	hsa-miR-510	CLIP-seq
MIRT1425799	hsa-miR-512-5p	CLIP-seq
MIRT1425800	hsa-miR-548aa	CLIP-seq
MIRT1425801	hsa-miR-548m	CLIP-seq
MIRT1425802	hsa-miR-575	CLIP-seq
MIRT1425803	hsa-miR-577	CLIP-seq
MIRT1425804	hsa-miR-592	CLIP-seq
MIRT1425805	hsa-miR-597	CLIP-seq
MIRT1425806	hsa-miR-607	CLIP-seq
MIRT1425807	hsa-miR-622	CLIP-seq
MIRT1425808	hsa-miR-892b	CLIP-seq
MIRT1425748	hsa-miR-105	CLIP-seq
MIRT1425809	hsa-miR-1178	CLIP-seq
MIRT1425810	hsa-miR-1183	CLIP-seq
MIRT1425811	hsa-miR-1227	CLIP-seq
MIRT1425812	hsa-miR-1251	CLIP-seq
MIRT1425751	hsa-miR-140-5p	CLIP-seq
MIRT1425813	hsa-miR-142-3p	CLIP-seq
MIRT1425814	hsa-miR-323b-3p	CLIP-seq
MIRT1425815	hsa-miR-330-3p	CLIP-seq
MIRT1425816	hsa-miR-3545-5p	CLIP-seq
MIRT1425768	hsa-miR-361-5p	CLIP-seq
MIRT1425778	hsa-miR-4277	CLIP-seq
MIRT1425817	hsa-miR-4428	CLIP-seq
MIRT1425818	hsa-miR-4457	CLIP-seq
MIRT1425819	hsa-miR-4460	CLIP-seq
MIRT1425820	hsa-miR-455-5p	CLIP-seq
MIRT1425786	hsa-miR-4637	CLIP-seq
MIRT1425821	hsa-miR-4662a-5p	CLIP-seq
MIRT1425822	hsa-miR-4719	CLIP-seq
MIRT1425823	hsa-miR-4796-5p	CLIP-seq
MIRT1425794	hsa-miR-495	CLIP-seq
MIRT1425824	hsa-miR-520d-5p	CLIP-seq
MIRT1425825	hsa-miR-524-5p	CLIP-seq
MIRT1425826	hsa-miR-548g	CLIP-seq
MIRT1425827	hsa-miR-548p	CLIP-seq
MIRT1425828	hsa-miR-556-5p	CLIP-seq
MIRT1425829	hsa-miR-610	CLIP-seq
MIRT1425746	hsa-miR-101	CLIP-seq
MIRT1425748	hsa-miR-105	CLIP-seq
MIRT1425809	hsa-miR-1178	CLIP-seq
MIRT1425810	hsa-miR-1183	CLIP-seq
MIRT1425811	hsa-miR-1227	CLIP-seq
MIRT2127555	hsa-miR-1228	CLIP-seq
MIRT2127556	hsa-miR-124	CLIP-seq
MIRT2127557	hsa-miR-1247	CLIP-seq
MIRT2127558	hsa-miR-1303	CLIP-seq
MIRT2127559	hsa-miR-132	CLIP-seq
MIRT2127560	hsa-miR-138	CLIP-seq
MIRT1425751	hsa-miR-140-5p	CLIP-seq
MIRT2127561	hsa-miR-141	CLIP-seq
MIRT1425813	hsa-miR-142-3p	CLIP-seq
MIRT1425752	hsa-miR-144	CLIP-seq
MIRT1425753	hsa-miR-145	CLIP-seq
MIRT1425755	hsa-miR-191	CLIP-seq
MIRT1425756	hsa-miR-193a-3p	CLIP-seq
MIRT1425757	hsa-miR-193b	CLIP-seq
MIRT2127562	hsa-miR-200a	CLIP-seq
MIRT2127563	hsa-miR-212	CLIP-seq
MIRT2127564	hsa-miR-224	CLIP-seq
MIRT1425760	hsa-miR-23a	CLIP-seq
MIRT1425761	hsa-miR-23b	CLIP-seq
MIRT1425762	hsa-miR-23c	CLIP-seq
MIRT1425763	hsa-miR-3064-5p	CLIP-seq
MIRT2127565	hsa-miR-3123	CLIP-seq
MIRT2127566	hsa-miR-3140-3p	CLIP-seq
MIRT2127567	hsa-miR-3149	CLIP-seq
MIRT2127568	hsa-miR-335	CLIP-seq
MIRT2127569	hsa-miR-342-3p	CLIP-seq
MIRT1425816	hsa-miR-3545-5p	CLIP-seq
MIRT1425767	hsa-miR-3611	CLIP-seq
MIRT1425768	hsa-miR-361-5p	CLIP-seq
MIRT2127570	hsa-miR-3620	CLIP-seq
MIRT2127571	hsa-miR-362-5p	CLIP-seq
MIRT1425769	hsa-miR-3652	CLIP-seq
MIRT2127572	hsa-miR-3653	CLIP-seq
MIRT2127573	hsa-miR-3658	CLIP-seq
MIRT2127574	hsa-miR-3662	CLIP-seq
MIRT2127575	hsa-miR-3667-3p	CLIP-seq
MIRT1425771	hsa-miR-369-3p	CLIP-seq
MIRT2127576	hsa-miR-3713	CLIP-seq
MIRT2127577	hsa-miR-3714	CLIP-seq
MIRT1425772	hsa-miR-374a	CLIP-seq
MIRT1425773	hsa-miR-374b	CLIP-seq
MIRT2127578	hsa-miR-3910	CLIP-seq
MIRT2127579	hsa-miR-3922-5p	CLIP-seq
MIRT2127580	hsa-miR-3973	CLIP-seq
MIRT2127581	hsa-miR-412	CLIP-seq
MIRT1425778	hsa-miR-4277	CLIP-seq
MIRT2127582	hsa-miR-4289	CLIP-seq
MIRT1425781	hsa-miR-4430	CLIP-seq
MIRT1425819	hsa-miR-4460	CLIP-seq
MIRT1425782	hsa-miR-4501	CLIP-seq
MIRT1425783	hsa-miR-4503	CLIP-seq
MIRT1425784	hsa-miR-4505	CLIP-seq
MIRT2127583	hsa-miR-450b-5p	CLIP-seq
MIRT2127584	hsa-miR-4511	CLIP-seq
MIRT2127585	hsa-miR-4517	CLIP-seq
MIRT2127586	hsa-miR-4536	CLIP-seq
MIRT1425820	hsa-miR-455-5p	CLIP-seq
MIRT1425786	hsa-miR-4637	CLIP-seq
MIRT2127587	hsa-miR-4652-3p	CLIP-seq
MIRT1425787	hsa-miR-4670-3p	CLIP-seq
MIRT2127588	hsa-miR-4696	CLIP-seq
MIRT1425789	hsa-miR-4699-3p	CLIP-seq
MIRT2127589	hsa-miR-4704-3p	CLIP-seq
MIRT2127590	hsa-miR-4705	CLIP-seq
MIRT2127591	hsa-miR-4709-3p	CLIP-seq
MIRT2127592	hsa-miR-4709-5p	CLIP-seq
MIRT2127593	hsa-miR-4717-3p	CLIP-seq
MIRT2127594	hsa-miR-4718	CLIP-seq
MIRT1425822	hsa-miR-4719	CLIP-seq
MIRT1425792	hsa-miR-4774-5p	CLIP-seq
MIRT1425794	hsa-miR-495	CLIP-seq
MIRT2127595	hsa-miR-500b	CLIP-seq
MIRT1425796	hsa-miR-501-3p	CLIP-seq
MIRT2127596	hsa-miR-501-5p	CLIP-seq
MIRT1425797	hsa-miR-502-3p	CLIP-seq
MIRT2127597	hsa-miR-502-5p	CLIP-seq
MIRT2127598	hsa-miR-506	CLIP-seq
MIRT2127599	hsa-miR-511	CLIP-seq
MIRT1425824	hsa-miR-520d-5p	CLIP-seq
MIRT2127600	hsa-miR-520g	CLIP-seq
MIRT2127601	hsa-miR-520h	CLIP-seq
MIRT1425825	hsa-miR-524-5p	CLIP-seq
MIRT2127602	hsa-miR-544	CLIP-seq
MIRT2127603	hsa-miR-548b-3p	CLIP-seq
MIRT1425826	hsa-miR-548g	CLIP-seq
MIRT1425801	hsa-miR-548m	CLIP-seq
MIRT2127604	hsa-miR-555	CLIP-seq
MIRT2127605	hsa-miR-582-5p	CLIP-seq
MIRT2127606	hsa-miR-605	CLIP-seq
MIRT2127607	hsa-miR-616	CLIP-seq
MIRT2127608	hsa-miR-654-3p	CLIP-seq
MIRT1425808	hsa-miR-892b	CLIP-seq
MIRT1425746	hsa-miR-101	CLIP-seq
MIRT1425747	hsa-miR-103b	CLIP-seq
MIRT1425748	hsa-miR-105	CLIP-seq
MIRT1425809	hsa-miR-1178	CLIP-seq
MIRT1425810	hsa-miR-1183	CLIP-seq
MIRT2127555	hsa-miR-1228	CLIP-seq
MIRT2127556	hsa-miR-124	CLIP-seq
MIRT2127557	hsa-miR-1247	CLIP-seq
MIRT1425812	hsa-miR-1251	CLIP-seq
MIRT2349296	hsa-miR-1262	CLIP-seq
MIRT2349297	hsa-miR-1296	CLIP-seq
MIRT2127559	hsa-miR-132	CLIP-seq
MIRT2127560	hsa-miR-138	CLIP-seq
MIRT1425751	hsa-miR-140-5p	CLIP-seq
MIRT2127561	hsa-miR-141	CLIP-seq
MIRT1425813	hsa-miR-142-3p	CLIP-seq
MIRT1425752	hsa-miR-144	CLIP-seq
MIRT1425753	hsa-miR-145	CLIP-seq
MIRT1425754	hsa-miR-153	CLIP-seq
MIRT2349298	hsa-miR-185	CLIP-seq
MIRT1425755	hsa-miR-191	CLIP-seq
MIRT1425756	hsa-miR-193a-3p	CLIP-seq
MIRT1425757	hsa-miR-193b	CLIP-seq
MIRT2127562	hsa-miR-200a	CLIP-seq
MIRT1425758	hsa-miR-200b	CLIP-seq
MIRT1425759	hsa-miR-200c	CLIP-seq
MIRT2127563	hsa-miR-212	CLIP-seq
MIRT2127564	hsa-miR-224	CLIP-seq
MIRT1425760	hsa-miR-23a	CLIP-seq
MIRT1425761	hsa-miR-23b	CLIP-seq
MIRT1425762	hsa-miR-23c	CLIP-seq
MIRT2349299	hsa-miR-2909	CLIP-seq
MIRT1425763	hsa-miR-3064-5p	CLIP-seq
MIRT2127565	hsa-miR-3123	CLIP-seq
MIRT2349300	hsa-miR-3127-5p	CLIP-seq
MIRT1425764	hsa-miR-3133	CLIP-seq
MIRT2127566	hsa-miR-3140-3p	CLIP-seq
MIRT2349301	hsa-miR-3146	CLIP-seq
MIRT2127567	hsa-miR-3149	CLIP-seq
MIRT2349302	hsa-miR-3163	CLIP-seq
MIRT2349303	hsa-miR-3177-5p	CLIP-seq
MIRT2349304	hsa-miR-3182	CLIP-seq
MIRT1425814	hsa-miR-323b-3p	CLIP-seq
MIRT1425815	hsa-miR-330-3p	CLIP-seq
MIRT2127568	hsa-miR-335	CLIP-seq
MIRT1425766	hsa-miR-337-3p	CLIP-seq
MIRT2127569	hsa-miR-342-3p	CLIP-seq
MIRT1425816	hsa-miR-3545-5p	CLIP-seq
MIRT1425767	hsa-miR-3611	CLIP-seq
MIRT1425768	hsa-miR-361-5p	CLIP-seq
MIRT2127570	hsa-miR-3620	CLIP-seq
MIRT2127571	hsa-miR-362-5p	CLIP-seq
MIRT1425769	hsa-miR-3652	CLIP-seq
MIRT2127572	hsa-miR-3653	CLIP-seq
MIRT2127573	hsa-miR-3658	CLIP-seq
MIRT2127574	hsa-miR-3662	CLIP-seq
MIRT2127575	hsa-miR-3667-3p	CLIP-seq
MIRT1425771	hsa-miR-369-3p	CLIP-seq
MIRT2127576	hsa-miR-3713	CLIP-seq
MIRT2127577	hsa-miR-3714	CLIP-seq
MIRT1425772	hsa-miR-374a	CLIP-seq
MIRT1425773	hsa-miR-374b	CLIP-seq
MIRT2127578	hsa-miR-3910	CLIP-seq
MIRT2349305	hsa-miR-3918	CLIP-seq
MIRT2127579	hsa-miR-3922-5p	CLIP-seq
MIRT2127580	hsa-miR-3973	CLIP-seq
MIRT1425776	hsa-miR-3978	CLIP-seq
MIRT2127581	hsa-miR-412	CLIP-seq
MIRT2349306	hsa-miR-4253	CLIP-seq
MIRT1425777	hsa-miR-4264	CLIP-seq
MIRT1425778	hsa-miR-4277	CLIP-seq
MIRT2127582	hsa-miR-4289	CLIP-seq
MIRT1425779	hsa-miR-429	CLIP-seq
MIRT2349307	hsa-miR-4302	CLIP-seq
MIRT2349308	hsa-miR-4306	CLIP-seq
MIRT2349309	hsa-miR-4307	CLIP-seq
MIRT2349310	hsa-miR-4310	CLIP-seq
MIRT2349311	hsa-miR-4314	CLIP-seq
MIRT1425780	hsa-miR-433	CLIP-seq
MIRT1425781	hsa-miR-4430	CLIP-seq
MIRT2349312	hsa-miR-4436b-3p	CLIP-seq
MIRT1425819	hsa-miR-4460	CLIP-seq
MIRT1425782	hsa-miR-4501	CLIP-seq
MIRT1425783	hsa-miR-4503	CLIP-seq
MIRT1425784	hsa-miR-4505	CLIP-seq
MIRT2127584	hsa-miR-4511	CLIP-seq
MIRT1425785	hsa-miR-4519	CLIP-seq
MIRT1425786	hsa-miR-4637	CLIP-seq
MIRT2349313	hsa-miR-4644	CLIP-seq
MIRT2127587	hsa-miR-4652-3p	CLIP-seq
MIRT2349314	hsa-miR-4659a-3p	CLIP-seq
MIRT2349315	hsa-miR-4659b-3p	CLIP-seq
MIRT1425821	hsa-miR-4662a-5p	CLIP-seq
MIRT1425787	hsa-miR-4670-3p	CLIP-seq
MIRT1425788	hsa-miR-4676-5p	CLIP-seq
MIRT2349316	hsa-miR-4685-5p	CLIP-seq
MIRT2349317	hsa-miR-4688	CLIP-seq
MIRT2349318	hsa-miR-4698	CLIP-seq
MIRT1425789	hsa-miR-4699-3p	CLIP-seq
MIRT2349319	hsa-miR-4700-3p	CLIP-seq
MIRT2349320	hsa-miR-4701-3p	CLIP-seq
MIRT2127589	hsa-miR-4704-3p	CLIP-seq
MIRT2127590	hsa-miR-4705	CLIP-seq
MIRT2127592	hsa-miR-4709-5p	CLIP-seq
MIRT2127593	hsa-miR-4717-3p	CLIP-seq
MIRT2349321	hsa-miR-4717-5p	CLIP-seq
MIRT2127594	hsa-miR-4718	CLIP-seq
MIRT1425822	hsa-miR-4719	CLIP-seq
MIRT1425790	hsa-miR-4760-5p	CLIP-seq
MIRT2349322	hsa-miR-4761-3p	CLIP-seq
MIRT2349323	hsa-miR-4762-3p	CLIP-seq
MIRT2349324	hsa-miR-4768-3p	CLIP-seq
MIRT1425791	hsa-miR-4773	CLIP-seq
MIRT1425792	hsa-miR-4774-5p	CLIP-seq
MIRT1425793	hsa-miR-4777-5p	CLIP-seq
MIRT2349325	hsa-miR-494	CLIP-seq
MIRT1425794	hsa-miR-495	CLIP-seq
MIRT1425795	hsa-miR-498	CLIP-seq
MIRT2127595	hsa-miR-500b	CLIP-seq
MIRT1425796	hsa-miR-501-3p	CLIP-seq
MIRT2127596	hsa-miR-501-5p	CLIP-seq
MIRT1425797	hsa-miR-502-3p	CLIP-seq
MIRT2127597	hsa-miR-502-5p	CLIP-seq
MIRT2127598	hsa-miR-506	CLIP-seq
MIRT1425798	hsa-miR-510	CLIP-seq
MIRT2127599	hsa-miR-511	CLIP-seq
MIRT1425799	hsa-miR-512-5p	CLIP-seq
MIRT1425824	hsa-miR-520d-5p	CLIP-seq
MIRT2127600	hsa-miR-520g	CLIP-seq
MIRT2127601	hsa-miR-520h	CLIP-seq
MIRT1425825	hsa-miR-524-5p	CLIP-seq
MIRT2127602	hsa-miR-544	CLIP-seq
MIRT2349326	hsa-miR-548ae	CLIP-seq
MIRT2349327	hsa-miR-548aj	CLIP-seq
MIRT2349328	hsa-miR-548am	CLIP-seq
MIRT2127603	hsa-miR-548b-3p	CLIP-seq
MIRT1425826	hsa-miR-548g	CLIP-seq
MIRT1425801	hsa-miR-548m	CLIP-seq
MIRT1425827	hsa-miR-548p	CLIP-seq
MIRT2349329	hsa-miR-548x	CLIP-seq
MIRT2127604	hsa-miR-555	CLIP-seq
MIRT2349330	hsa-miR-561	CLIP-seq
MIRT1425802	hsa-miR-575	CLIP-seq
MIRT1425803	hsa-miR-577	CLIP-seq
MIRT2127605	hsa-miR-582-5p	CLIP-seq
MIRT2349331	hsa-miR-591	CLIP-seq
MIRT2127606	hsa-miR-605	CLIP-seq
MIRT2127607	hsa-miR-616	CLIP-seq
MIRT2349332	hsa-miR-618	CLIP-seq
MIRT1425807	hsa-miR-622	CLIP-seq
MIRT1425808	hsa-miR-892b	CLIP-seq
MIRT1425809	hsa-miR-1178	CLIP-seq
MIRT2127555	hsa-miR-1228	CLIP-seq
MIRT1425753	hsa-miR-145	CLIP-seq
MIRT1425755	hsa-miR-191	CLIP-seq
MIRT1425760	hsa-miR-23a	CLIP-seq
MIRT1425761	hsa-miR-23b	CLIP-seq
MIRT1425762	hsa-miR-23c	CLIP-seq
MIRT2349300	hsa-miR-3127-5p	CLIP-seq
MIRT2349306	hsa-miR-4253	CLIP-seq
MIRT2349309	hsa-miR-4307	CLIP-seq
MIRT2349317	hsa-miR-4688	CLIP-seq
MIRT2127589	hsa-miR-4704-3p	CLIP-seq
MIRT1425790	hsa-miR-4760-5p	CLIP-seq
MIRT1425792	hsa-miR-4774-5p	CLIP-seq
MIRT2349331	hsa-miR-591	CLIP-seq
MIRT1425746	hsa-miR-101	CLIP-seq
MIRT1425748	hsa-miR-105	CLIP-seq
MIRT1425752	hsa-miR-144	CLIP-seq
MIRT1425777	hsa-miR-4264	CLIP-seq
MIRT1425780	hsa-miR-433	CLIP-seq
MIRT1425793	hsa-miR-4777-5p	CLIP-seq
MIRT1425798	hsa-miR-510	CLIP-seq
MIRT1425799	hsa-miR-512-5p	CLIP-seq
MIRT1425801	hsa-miR-548m	CLIP-seq
MIRT1425803	hsa-miR-577	CLIP-seq
MIRT1425807	hsa-miR-622	CLIP-seq
MIRT1425746	hsa-miR-101	CLIP-seq
MIRT1425748	hsa-miR-105	CLIP-seq
MIRT1425752	hsa-miR-144	CLIP-seq
MIRT1425777	hsa-miR-4264	CLIP-seq
MIRT1425780	hsa-miR-433	CLIP-seq
MIRT1425793	hsa-miR-4777-5p	CLIP-seq
MIRT1425798	hsa-miR-510	CLIP-seq
MIRT1425799	hsa-miR-512-5p	CLIP-seq
MIRT2349326	hsa-miR-548ae	CLIP-seq
MIRT2349327	hsa-miR-548aj	CLIP-seq
MIRT2349328	hsa-miR-548am	CLIP-seq
MIRT2349329	hsa-miR-548x	CLIP-seq
MIRT1425803	hsa-miR-577	CLIP-seq
MIRT1425807	hsa-miR-622	CLIP-seq

Transcription factors

Transcription factor	Regulation	Reference
AR	Activation	18535113
HDAC1	Repression	20580679

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0002102	Component	Podosome	IEA
GO:0005515	Function	Protein binding	IPI	9707407, 11042084, 11734628, 12154091, 16944923, 17015620, 17724469, 18823282, 19332538, 20164257, 20850437, 21402783, 22262837, 23885123, 25753039, 28661558, 29366904, 30992345, 31473225
GO:0005516	Function	Calmodulin binding	IEA
GO:0005737	Component	Cytoplasm	IDA	11734628
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	IBA	21873635
GO:0005886	Component	Plasma membrane	IDA	11090614
GO:0005886	Component	Plasma membrane	ISS
GO:0005886	Component	Plasma membrane	TAS
GO:0005912	Component	Adherens junction	TAS	8486731
GO:0005921	Component	Gap junction	ISS
GO:0005923	Component	Bicellular tight junction	IBA	21873635
GO:0005923	Component	Bicellular tight junction	IDA	11734628, 14757759, 18823282, 22006950
GO:0007043	Process	Cell-cell junction assembly	TAS	8486731
GO:0008284	Process	Positive regulation of cell population proliferation	IMP	29771433
GO:0016323	Component	Basolateral plasma membrane	IDA	16427635
GO:0030054	Component	Cell junction	IDA	28169360
GO:0030054	Component	Cell junction	TAS
GO:0030335	Process	Positive regulation of cell migration	IMP	25753039
GO:0031032	Process	Actomyosin structure organization	IMP	25753039
GO:0032991	Component	Protein-containing complex	IDA	25753039
GO:0034334	Process	Adherens junction maintenance	IMP	25753039
GO:0035329	Process	Hippo signaling	TAS
GO:0035633	Process	Maintenance of blood-brain barrier	NAS	30280653
GO:0042995	Component	Cell projection	IEA
GO:0043066	Process	Negative regulation of apoptotic process	IMP	29771433
GO:0043296	Component	Apical junction complex	IDA	16427635
GO:0045177	Component	Apical part of cell	IDA	22006950
GO:0045216	Process	Cell-cell junction organization	IBA	21873635
GO:0045216	Process	Cell-cell junction organization	IMP	25753039
GO:0045296	Function	Cadherin binding	HDA	25468996
GO:0050839	Function	Cell adhesion molecule binding	IBA	21873635
GO:0051493	Process	Regulation of cytoskeleton organization	IMP	25753039
GO:0051497	Process	Negative regulation of stress fiber assembly	ISS
GO:0070160	Component	Tight junction	IDA	22855531, 27037668, 30734065
GO:0070160	Component	Tight junction	IMP	24854121
GO:0071896	Process	Protein localization to adherens junction	IMP	25753039
GO:0090557	Process	Establishment of endothelial intestinal barrier	IBA	21873635
GO:0090557	Process	Establishment of endothelial intestinal barrier	IMP	23885123
GO:0098609	Process	Cell-cell adhesion	IBA	21873635
GO:0150105	Process	Protein localization to cell-cell junction	IBA	21873635
GO:0150105	Process	Protein localization to cell-cell junction	IMP	25753039
GO:1901888	Process	Regulation of cell junction assembly	IMP	25753039
GO:1902396	Process	Protein localization to bicellular tight junction	IMP	25753039
GO:1903672	Process	Positive regulation of sprouting angiogenesis	IMP	25753039
GO:1905605	Process	Positive regulation of blood-brain barrier permeability	IBA	21873635
GO:1905605	Process	Positive regulation of blood-brain barrier permeability	IMP	24854121
GO:2000049	Process	Positive regulation of cell-cell adhesion mediated by cadherin	IMP	25753039
GO:2000250	Process	Negative regulation of actin cytoskeleton reorganization	IMP	25753039
GO:2000810	Process	Regulation of bicellular tight junction assembly	IMP	25753039
GO:2000810	Process	Regulation of bicellular tight junction assembly	TAS

Other IDs

• MIM: 601009
• HGNC: 11827
• e!Ensembl: ENSG00000104067

Protein

• UniProt ID: Q07157
• Protein name: Tight junction protein 1 (Tight junction protein ZO-1) (Zona occludens protein 1) (Zonula occludens protein 1)
• Protein function: TJP1, TJP2, and TJP3 are closely related scaffolding proteins that link tight junction (TJ) transmembrane proteins such as claudins, junctional adhesion molecules, and occludin to the actin cytoskeleton (PubMed:7798316, PubMed:9792688). Forms a
• PDB: 2H2B, 2H2C, 2H3M, 2JWE, 2KXR, 2KXS, 2RCZ, 3CYY, 3LH5, 3SHU, 3SHW, 3TSV, 3TSW, 3TSZ, 4OEO, 4OEP, 4Q2Q, 4YYX
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00595	PDZ	23 → 107	PDZ domain	Domain
  PF00595	PDZ	186 → 261	PDZ domain	Domain
  PF00595	PDZ	422 → 501	PDZ domain	Domain
  PF07653	SH3_2	520 → 582	Variant SH3 domain	Domain
  PF00625	Guanylate_kin	681 → 793	Guanylate kinase	Domain
  PF00791	ZU5	1635 → 1727	ZU5 domain	Family

• Sequence:

  MSARAAAAKSTAMEETAIWEQHTVTLHRAPGFGFGIAISGGRDNPHFQSGETSIVISDVL
  KGGPAEGQLQENDRVAMVNGVSMDNVEHAFAVQQLRKSGKNAKITIRRKKKVQIPVSRPD
  PEPVSDNEEDSYDEEIHDPRSGRSGVVNRRSEKIWPRDRSASRERSLSPRSDRRSVASSQ
  PAKPTKVTLVKSRKNEEYGLRLASHIFVKEISQDSLAARDGNIQEGDVVLKINGTVTENM
  SLTDAKTLIERSKGKLKMVVQRDERATLLNVPDLSDSIHSANASERDDISEIQSLASDHS
  GRSHDRPPRRSRSRSPDQRSEPSDHSRHSPQQPSNGSLRSRDEERISKPGAVSTPVKHAD
  DHTPKTVEEVTVERNEKQTPSLPEPKPVYAQVGQPDVDLPVSPSDGVLPNSTHEDGILRP
  SMKLVKFRKGDSVGLRLAGGNDVGIFVAGVLEDSPAAKEGLEEGDQILRVNNVDFTNIIR
  EEAVLFLLDLPKGEEVTILAQKKKDVYRRIVESDVGDSFYIRTHFEYEKESPYGLSFNKG
  EVFRVVDTLYNGKLGSWLAIRIGKNHKEVERGIIPNKNRAEQLASVQYTLPKTAGGDRAD
  FWRFRGLRSSKRNLRKSREDLSAQPVQTKFPAYERVVLREAGFLRPVTIFGPIADVAREK
  LAREEPDIYQIAKSEPRDAGTDQRSSGIIRLHTIKQIIDQDKHALLDVTPNAVDRLNYAQ
  WYPIVVFLNPDSKQGVKTMRMRLCPESRKSARKLYERSHKLRKNNHHLFTTTINLNSMND
  GWYGALKEAIQQQQNQLVWVSEGKADGATSDDLDLHDDRLSYLSAPGSEYSMYSTDSRHT
  SDYEDTDTEGGAYTDQELDETLNDEVGTPPESAITRSSEPVREDSSGMHHENQTYPPYSP
  QAQPQPIHRIDSPGFKPASQQKAEASSPVPYLSPETNPASSTSAVNHNVNLTNVRLEEPT
  PAPSTSYSPQADSLRTPSTEAAHIMLRDQEPSLSSHVDPTKVYRKDPYPEEMMRQNHVLK
  QPAVSHPGHRPDKEPNLTYEPQLPYVEKQASRDLEQPTYRYESSSYTDQFSRNYEHRLRY
  EDRVPMYEEQWSYYDDKQPYPSRPPFDNQHSQDLDSRQHPEESSERGYFPRFEEPAPLSY
  DSRPRYEQAPRASALRHEEQPAPGYDTHGRLRPEAQPHPSAGPKPAESKQYFEQYSRSYE
  QVPPQGFTSRAGHFEPLHGAAAVPPLIPSSQHKPEALPSNTKPLPPPPTQTEEEEDPAMK
  PQSVLTRVKMFENKRSASLETKKDVNDTGSFKPPEVASKPSGAPIIGPKPTSQNQFSEHD
  KTLYRIPEPQKPQLKPPEDIVRSNHYDPEEDEEYYRKQLSYFDRRSFENKPPAHIAASHL
  SEPAKPAHSQNQSNFSSYSSKGKPPEADGVDRSFGEKRYEPIQATPPPPPLPSQYAQPSQ
  PVTSASLHIHSKGAHGEGNSVSLDFQNSLVSKPDPPPSQNKPATFRPPNREDTAQAAFYP
  QKSFPDKAPVNGTEQTQKTVTPAYNRFTPKPYTSSARPFERKFESPKFNHNLLPSETAHK
  PDLSSKTPTSPKTLVKSHSLAQPPEFDSGVETFSIHAEKPKYQINNISTVPKAIPVSPSA
  VEEDEDEDGHTVVATARGIFNSNGGVLSSIETGVSIIIPQGAIPEGVEQEIYFKVCRDNS
  ILPPLDKEKGETLLSPLVMCGPHGLKFLKPVELRLPHCDPKTWQNKCLPGDPNYLVGANC
  VSVLIDHF

• Sequence length: 1748