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TAB2 (TGF-beta activated kinase 1 (MAP3K7) binding protein 2)

Gene

23118

TGF-beta activated kinase 1 (MAP3K7) binding protein 2

TAB2

CHTD2, MAP3K7IP2, TAB-2

6q25.1

The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, and it thus serves as an adapto

Show/Hide all(13)

SNP ID	Visualize variation	Clinical significance	Consequence
rs143213478	A>G	Conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, coding sequence variant, synonymous variant
rs267607100	C>A	Pathogenic	Coding sequence variant, missense variant, genic downstream transcript variant
rs267607101	C>T	Pathogenic	Coding sequence variant, missense variant, genic downstream transcript variant
rs886041646	C>-	Pathogenic	Genic downstream transcript variant, coding sequence variant, stop gained
rs1057517934	C>T	Likely-pathogenic	Genic downstream transcript variant, stop gained, coding sequence variant
rs1057518015	C>T	Likely-pathogenic	Genic downstream transcript variant, stop gained, coding sequence variant
rs1057518422	C>T	Likely-pathogenic	Genic downstream transcript variant, stop gained, coding sequence variant
rs1057518437	C>A	Pathogenic	Genic downstream transcript variant, stop gained, coding sequence variant
rs1064795547	CA>-	Pathogenic	Genic downstream transcript variant, coding sequence variant, frameshift variant
rs1479104927	C>G,T	Pathogenic-likely-pathogenic	Genic downstream transcript variant, stop gained, missense variant, coding sequence variant
rs1554263268	C>-	Likely-pathogenic	Genic downstream transcript variant, coding sequence variant, frameshift variant
rs1554263321	C>T	Pathogenic	Genic downstream transcript variant, coding sequence variant, stop gained
rs1562443558	T>A	Pathogenic	Genic downstream transcript variant, coding sequence variant, stop gained

Show/Hide all(401)

miRTarBase ID	miRNA	Experiments	Reference
MIRT000289	hsa-miR-155-5p	Review	20029422
MIRT000289	hsa-miR-155-5p	Luciferase reporter assay, Microarray, qRT-PCR, Western blot	19193853
MIRT005057	hsa-let-7b-5p	Microarray	17699775
MIRT000289	hsa-miR-155-5p	Luciferase reporter assay, Microarray, qRT-PCR, Western blot	20852130
MIRT007040	hsa-miR-23b-3p	Luciferase reporter assay	22660635
MIRT000289	hsa-miR-155-5p	Luciferase reporter assay	23449975
MIRT000289	hsa-miR-155-5p	Luciferase reporter assay	23449975
MIRT000289	hsa-miR-155-5p	Reporter assay	20680360
MIRT000289	hsa-miR-155-5p	Reporter assay;Other	20584899
MIRT025198	hsa-miR-181a-5p	Sequencing	20371350
MIRT027769	hsa-miR-98-5p	Microarray	19088304
MIRT052592	hsa-let-7a-5p	CLASH	23622248
MIRT052592	hsa-let-7a-5p	CLASH	23622248
MIRT005057	hsa-let-7b-5p	CLASH	23622248
MIRT051388	hsa-let-7f-5p	CLASH	23622248
MIRT048189	hsa-miR-196a-5p	CLASH	23622248
MIRT046408	hsa-miR-15b-5p	CLASH	23622248
MIRT052996	hsa-miR-142-3p	Luciferase reporter assay, Western blot	22493297
MIRT052996	hsa-miR-142-3p	Luciferase reporter assay, Western blot	22493297
MIRT544320	hsa-miR-495-3p	PAR-CLIP	21572407
MIRT544319	hsa-miR-5688	PAR-CLIP	21572407
MIRT544318	hsa-miR-7-1-3p	PAR-CLIP	21572407
MIRT544317	hsa-miR-7-2-3p	PAR-CLIP	21572407
MIRT544316	hsa-miR-651-3p	PAR-CLIP	21572407
MIRT492110	hsa-miR-3148	PAR-CLIP	21572407
MIRT492122	hsa-miR-199a-3p	PAR-CLIP	23592263
MIRT492121	hsa-miR-3129-5p	PAR-CLIP	23592263
MIRT492120	hsa-miR-199b-3p	PAR-CLIP	23592263
MIRT492119	hsa-miR-548m	PAR-CLIP	23592263
MIRT492118	hsa-miR-6783-5p	PAR-CLIP	23592263
MIRT492117	hsa-miR-4678	PAR-CLIP	23592263
MIRT492116	hsa-miR-936	PAR-CLIP	23592263
MIRT492115	hsa-miR-3184-5p	PAR-CLIP	23592263
MIRT492114	hsa-miR-423-5p	PAR-CLIP	23592263
MIRT492113	hsa-miR-1914-3p	PAR-CLIP	23592263
MIRT492112	hsa-miR-5194	PAR-CLIP	23592263
MIRT492111	hsa-miR-6738-5p	PAR-CLIP	23592263
MIRT492110	hsa-miR-3148	PAR-CLIP	23592263
MIRT492108	hsa-miR-4668-5p	PAR-CLIP	23592263
MIRT492109	hsa-miR-1292-5p	PAR-CLIP	23592263
MIRT492106	hsa-miR-4471	PAR-CLIP	23592263
MIRT492107	hsa-miR-8059	PAR-CLIP	23592263
MIRT492105	hsa-miR-5681b	PAR-CLIP	23592263
MIRT492104	hsa-miR-6073	PAR-CLIP	23592263
MIRT492103	hsa-miR-222-5p	PAR-CLIP	23592263
MIRT492102	hsa-miR-6734-5p	PAR-CLIP	23592263
MIRT492101	hsa-miR-450a-1-3p	PAR-CLIP	23592263
MIRT449742	hsa-miR-4311	PAR-CLIP	22100165
MIRT449743	hsa-miR-1276	PAR-CLIP	22100165
MIRT449741	hsa-miR-583	PAR-CLIP	22100165
MIRT449740	hsa-miR-8063	PAR-CLIP	22100165
MIRT449739	hsa-miR-4698	PAR-CLIP	22100165
MIRT449738	hsa-miR-4708-5p	PAR-CLIP	22100165
MIRT449737	hsa-miR-655-5p	PAR-CLIP	22100165
MIRT449736	hsa-miR-377-5p	PAR-CLIP	22100165
MIRT449735	hsa-miR-6086	PAR-CLIP	22100165
MIRT449734	hsa-miR-1273e	PAR-CLIP	22100165
MIRT052996	hsa-miR-142-3p	HITS-CLIP	22473208
MIRT000289	hsa-miR-155-5p	HITS-CLIP	22473208
MIRT052996	hsa-miR-142-3p	HITS-CLIP	22473208
MIRT000289	hsa-miR-155-5p	HITS-CLIP	22473208
MIRT735169	hsa-miR-27b-5p	Luciferase reporter assay, Western blotting, qRT-PCR, ELISA	33174006
MIRT735381	hsa-miR-146a-5p	qRT-PCR	31739406
MIRT544320	hsa-miR-495-3p	PAR-CLIP	21572407
MIRT544319	hsa-miR-5688	PAR-CLIP	21572407
MIRT544318	hsa-miR-7-1-3p	PAR-CLIP	21572407
MIRT544317	hsa-miR-7-2-3p	PAR-CLIP	21572407
MIRT544316	hsa-miR-651-3p	PAR-CLIP	21572407
MIRT492110	hsa-miR-3148	PAR-CLIP	21572407
MIRT492122	hsa-miR-199a-3p	PAR-CLIP	23592263
MIRT492121	hsa-miR-3129-5p	PAR-CLIP	23592263
MIRT492120	hsa-miR-199b-3p	PAR-CLIP	23592263
MIRT492119	hsa-miR-548m	PAR-CLIP	23592263
MIRT492118	hsa-miR-6783-5p	PAR-CLIP	23592263
MIRT492117	hsa-miR-4678	PAR-CLIP	23592263
MIRT492116	hsa-miR-936	PAR-CLIP	23592263
MIRT492115	hsa-miR-3184-5p	PAR-CLIP	23592263
MIRT492114	hsa-miR-423-5p	PAR-CLIP	23592263
MIRT492113	hsa-miR-1914-3p	PAR-CLIP	23592263
MIRT492112	hsa-miR-5194	PAR-CLIP	23592263
MIRT492111	hsa-miR-6738-5p	PAR-CLIP	23592263
MIRT492110	hsa-miR-3148	PAR-CLIP	23592263
MIRT492108	hsa-miR-4668-5p	PAR-CLIP	23592263
MIRT492109	hsa-miR-1292-5p	PAR-CLIP	23592263
MIRT492106	hsa-miR-4471	PAR-CLIP	23592263
MIRT492107	hsa-miR-8059	PAR-CLIP	23592263
MIRT492105	hsa-miR-5681b	PAR-CLIP	23592263
MIRT492104	hsa-miR-6073	PAR-CLIP	23592263
MIRT492103	hsa-miR-222-5p	PAR-CLIP	23592263
MIRT492102	hsa-miR-6734-5p	PAR-CLIP	23592263
MIRT492101	hsa-miR-450a-1-3p	PAR-CLIP	23592263
MIRT449742	hsa-miR-4311	PAR-CLIP	22100165
MIRT449743	hsa-miR-1276	PAR-CLIP	22100165
MIRT449741	hsa-miR-583	PAR-CLIP	22100165
MIRT449740	hsa-miR-8063	PAR-CLIP	22100165
MIRT449739	hsa-miR-4698	PAR-CLIP	22100165
MIRT449738	hsa-miR-4708-5p	PAR-CLIP	22100165
MIRT449737	hsa-miR-655-5p	PAR-CLIP	22100165
MIRT449736	hsa-miR-377-5p	PAR-CLIP	22100165
MIRT449735	hsa-miR-6086	PAR-CLIP	22100165
MIRT449734	hsa-miR-1273e	PAR-CLIP	22100165
MIRT1408143	hsa-miR-1200	CLIP-seq
MIRT1408144	hsa-miR-1273g	CLIP-seq
MIRT1408145	hsa-miR-1302	CLIP-seq
MIRT1408146	hsa-miR-1303	CLIP-seq
MIRT1408147	hsa-miR-141	CLIP-seq
MIRT1408148	hsa-miR-181a	CLIP-seq
MIRT1408149	hsa-miR-181b	CLIP-seq
MIRT1408150	hsa-miR-181c	CLIP-seq
MIRT1408151	hsa-miR-181d	CLIP-seq
MIRT1408152	hsa-miR-1912	CLIP-seq
MIRT1408153	hsa-miR-200a	CLIP-seq
MIRT1408154	hsa-miR-204	CLIP-seq
MIRT1408155	hsa-miR-211	CLIP-seq
MIRT1408156	hsa-miR-3065-3p	CLIP-seq
MIRT1408157	hsa-miR-3121-5p	CLIP-seq
MIRT1408158	hsa-miR-3123	CLIP-seq
MIRT1408159	hsa-miR-3127-5p	CLIP-seq
MIRT1408160	hsa-miR-3130-5p	CLIP-seq
MIRT1408161	hsa-miR-3184	CLIP-seq
MIRT1408162	hsa-miR-3189-5p	CLIP-seq
MIRT1408163	hsa-miR-339-5p	CLIP-seq
MIRT1408164	hsa-miR-3545-3p	CLIP-seq
MIRT1408165	hsa-miR-3613-3p	CLIP-seq
MIRT1408166	hsa-miR-3925-5p	CLIP-seq
MIRT1408167	hsa-miR-3943	CLIP-seq
MIRT1408168	hsa-miR-4262	CLIP-seq
MIRT1408169	hsa-miR-4263	CLIP-seq
MIRT1408170	hsa-miR-4270	CLIP-seq
MIRT1408171	hsa-miR-4291	CLIP-seq
MIRT1408172	hsa-miR-4298	CLIP-seq
MIRT1408173	hsa-miR-4323	CLIP-seq
MIRT1408174	hsa-miR-4441	CLIP-seq
MIRT1408175	hsa-miR-4446-3p	CLIP-seq
MIRT1408176	hsa-miR-4482	CLIP-seq
MIRT1408177	hsa-miR-4490	CLIP-seq
MIRT1408178	hsa-miR-4503	CLIP-seq
MIRT1408179	hsa-miR-4506	CLIP-seq
MIRT1408180	hsa-miR-4635	CLIP-seq
MIRT1408181	hsa-miR-4662a-3p	CLIP-seq
MIRT1408182	hsa-miR-4672	CLIP-seq
MIRT1408183	hsa-miR-4675	CLIP-seq
MIRT1408184	hsa-miR-4719	CLIP-seq
MIRT1408185	hsa-miR-4741	CLIP-seq
MIRT1408186	hsa-miR-4755-5p	CLIP-seq
MIRT1408187	hsa-miR-4760-5p	CLIP-seq
MIRT1408188	hsa-miR-4768-5p	CLIP-seq
MIRT1408189	hsa-miR-501-5p	CLIP-seq
MIRT1408190	hsa-miR-515-5p	CLIP-seq
MIRT1408191	hsa-miR-520d-5p	CLIP-seq
MIRT1408192	hsa-miR-524-5p	CLIP-seq
MIRT1408193	hsa-miR-526b	CLIP-seq
MIRT1408194	hsa-miR-548a-3p	CLIP-seq
MIRT1408195	hsa-miR-548aa	CLIP-seq
MIRT1408196	hsa-miR-548ac	CLIP-seq
MIRT1408197	hsa-miR-548ae	CLIP-seq
MIRT1408198	hsa-miR-548aj	CLIP-seq
MIRT1408199	hsa-miR-548am	CLIP-seq
MIRT1408200	hsa-miR-548d-3p	CLIP-seq
MIRT1408201	hsa-miR-548e	CLIP-seq
MIRT1408202	hsa-miR-548f	CLIP-seq
MIRT1408203	hsa-miR-548x	CLIP-seq
MIRT1408204	hsa-miR-548z	CLIP-seq
MIRT1408205	hsa-miR-576-3p	CLIP-seq
MIRT1408206	hsa-miR-578	CLIP-seq
MIRT1408207	hsa-miR-623	CLIP-seq
MIRT1408208	hsa-miR-670	CLIP-seq
MIRT1408209	hsa-miR-7	CLIP-seq
MIRT1408210	hsa-miR-935	CLIP-seq
MIRT1408211	hsa-miR-942	CLIP-seq
MIRT2122406	hsa-miR-1228	CLIP-seq
MIRT2122407	hsa-miR-1245b-3p	CLIP-seq
MIRT2122408	hsa-miR-1269	CLIP-seq
MIRT2122409	hsa-miR-1269b	CLIP-seq
MIRT2122410	hsa-miR-127-5p	CLIP-seq
MIRT2122411	hsa-miR-1288	CLIP-seq
MIRT2122412	hsa-miR-1297	CLIP-seq
MIRT2122413	hsa-miR-140-3p	CLIP-seq
MIRT1408147	hsa-miR-141	CLIP-seq
MIRT2122414	hsa-miR-1911	CLIP-seq
MIRT2122415	hsa-miR-1913	CLIP-seq
MIRT1408153	hsa-miR-200a	CLIP-seq
MIRT2122416	hsa-miR-26a	CLIP-seq
MIRT2122417	hsa-miR-26b	CLIP-seq
MIRT2122418	hsa-miR-27a	CLIP-seq
MIRT2122419	hsa-miR-27b	CLIP-seq
MIRT2122420	hsa-miR-297	CLIP-seq
MIRT1408159	hsa-miR-3127-5p	CLIP-seq
MIRT2122421	hsa-miR-3143	CLIP-seq
MIRT2122422	hsa-miR-3159	CLIP-seq
MIRT1408162	hsa-miR-3189-5p	CLIP-seq
MIRT2122423	hsa-miR-324-3p	CLIP-seq
MIRT2122424	hsa-miR-3591-3p	CLIP-seq
MIRT2122425	hsa-miR-3655	CLIP-seq
MIRT2122426	hsa-miR-3668	CLIP-seq
MIRT2122427	hsa-miR-3691-3p	CLIP-seq
MIRT2122428	hsa-miR-3922-5p	CLIP-seq
MIRT2122429	hsa-miR-3977	CLIP-seq
MIRT2122430	hsa-miR-412	CLIP-seq
MIRT2122431	hsa-miR-4255	CLIP-seq
MIRT1408170	hsa-miR-4270	CLIP-seq
MIRT2122432	hsa-miR-4276	CLIP-seq
MIRT2122433	hsa-miR-4302	CLIP-seq
MIRT2122434	hsa-miR-4326	CLIP-seq
MIRT1408174	hsa-miR-4441	CLIP-seq
MIRT2122435	hsa-miR-4465	CLIP-seq
MIRT2122436	hsa-miR-4515	CLIP-seq
MIRT2122437	hsa-miR-4659a-3p	CLIP-seq
MIRT2122438	hsa-miR-4659b-3p	CLIP-seq
MIRT2122439	hsa-miR-4670-3p	CLIP-seq
MIRT2122440	hsa-miR-4677-5p	CLIP-seq
MIRT2122441	hsa-miR-4694-3p	CLIP-seq
MIRT2122442	hsa-miR-4740-5p	CLIP-seq
MIRT2122443	hsa-miR-4753-5p	CLIP-seq
MIRT2122444	hsa-miR-4758-3p	CLIP-seq
MIRT2122445	hsa-miR-4762-3p	CLIP-seq
MIRT2122446	hsa-miR-4797-5p	CLIP-seq
MIRT2122447	hsa-miR-513a-5p	CLIP-seq
MIRT1408193	hsa-miR-526b	CLIP-seq
MIRT2122448	hsa-miR-567	CLIP-seq
MIRT1408206	hsa-miR-578	CLIP-seq
MIRT1408209	hsa-miR-7	CLIP-seq
MIRT2122449	hsa-miR-759	CLIP-seq
MIRT1408210	hsa-miR-935	CLIP-seq
MIRT2344694	hsa-miR-101	CLIP-seq
MIRT2344695	hsa-miR-1264	CLIP-seq
MIRT2122408	hsa-miR-1269	CLIP-seq
MIRT2122409	hsa-miR-1269b	CLIP-seq
MIRT2344696	hsa-miR-1279	CLIP-seq
MIRT2122411	hsa-miR-1288	CLIP-seq
MIRT2344697	hsa-miR-1293	CLIP-seq
MIRT2344698	hsa-miR-144	CLIP-seq
MIRT2344699	hsa-miR-183	CLIP-seq
MIRT2122415	hsa-miR-1913	CLIP-seq
MIRT2344700	hsa-miR-2116	CLIP-seq
MIRT2344701	hsa-miR-219-5p	CLIP-seq
MIRT2344702	hsa-miR-2682	CLIP-seq
MIRT2122418	hsa-miR-27a	CLIP-seq
MIRT2122419	hsa-miR-27b	CLIP-seq
MIRT1408159	hsa-miR-3127-5p	CLIP-seq
MIRT2122422	hsa-miR-3159	CLIP-seq
MIRT2344703	hsa-miR-3170	CLIP-seq
MIRT1408162	hsa-miR-3189-5p	CLIP-seq
MIRT2122423	hsa-miR-324-3p	CLIP-seq
MIRT2344704	hsa-miR-34a	CLIP-seq
MIRT2344705	hsa-miR-34c-5p	CLIP-seq
MIRT2122427	hsa-miR-3691-3p	CLIP-seq
MIRT2344706	hsa-miR-377	CLIP-seq
MIRT2122428	hsa-miR-3922-5p	CLIP-seq
MIRT2122430	hsa-miR-412	CLIP-seq
MIRT2344707	hsa-miR-4260	CLIP-seq
MIRT1408170	hsa-miR-4270	CLIP-seq
MIRT1408171	hsa-miR-4291	CLIP-seq
MIRT2344708	hsa-miR-4421	CLIP-seq
MIRT2344709	hsa-miR-4423-3p	CLIP-seq
MIRT2344710	hsa-miR-4427	CLIP-seq
MIRT1408174	hsa-miR-4441	CLIP-seq
MIRT2344711	hsa-miR-4483	CLIP-seq
MIRT2344712	hsa-miR-4496	CLIP-seq
MIRT2344713	hsa-miR-449a	CLIP-seq
MIRT2344714	hsa-miR-449b	CLIP-seq
MIRT2344715	hsa-miR-449c	CLIP-seq
MIRT2122436	hsa-miR-4515	CLIP-seq
MIRT2344716	hsa-miR-4536	CLIP-seq
MIRT2122437	hsa-miR-4659a-3p	CLIP-seq
MIRT2122438	hsa-miR-4659b-3p	CLIP-seq
MIRT1408182	hsa-miR-4672	CLIP-seq
MIRT2344717	hsa-miR-4680-3p	CLIP-seq
MIRT2344718	hsa-miR-4691-3p	CLIP-seq
MIRT2122441	hsa-miR-4694-3p	CLIP-seq
MIRT2344719	hsa-miR-4709-5p	CLIP-seq
MIRT2122442	hsa-miR-4740-5p	CLIP-seq
MIRT2122443	hsa-miR-4753-5p	CLIP-seq
MIRT2122444	hsa-miR-4758-3p	CLIP-seq
MIRT2344720	hsa-miR-4782-3p	CLIP-seq
MIRT2344721	hsa-miR-4796-5p	CLIP-seq
MIRT2122446	hsa-miR-4797-5p	CLIP-seq
MIRT2122447	hsa-miR-513a-5p	CLIP-seq
MIRT2344722	hsa-miR-518a-5p	CLIP-seq
MIRT2344723	hsa-miR-522	CLIP-seq
MIRT2344724	hsa-miR-527	CLIP-seq
MIRT2344725	hsa-miR-545	CLIP-seq
MIRT2344726	hsa-miR-582-5p	CLIP-seq
MIRT2344727	hsa-miR-639	CLIP-seq
MIRT2344728	hsa-miR-656	CLIP-seq
MIRT1408209	hsa-miR-7	CLIP-seq
MIRT2122449	hsa-miR-759	CLIP-seq
MIRT2344729	hsa-miR-940	CLIP-seq
MIRT2344702	hsa-miR-2682	CLIP-seq
MIRT2344704	hsa-miR-34a	CLIP-seq
MIRT2344705	hsa-miR-34c-5p	CLIP-seq
MIRT2344709	hsa-miR-4423-3p	CLIP-seq
MIRT2344713	hsa-miR-449a	CLIP-seq
MIRT2344714	hsa-miR-449b	CLIP-seq
MIRT2344715	hsa-miR-449c	CLIP-seq
MIRT1408182	hsa-miR-4672	CLIP-seq
MIRT2122440	hsa-miR-4677-5p	CLIP-seq
MIRT2344729	hsa-miR-940	CLIP-seq
MIRT2122406	hsa-miR-1228	CLIP-seq
MIRT2122408	hsa-miR-1269	CLIP-seq
MIRT2122409	hsa-miR-1269b	CLIP-seq
MIRT2122411	hsa-miR-1288	CLIP-seq
MIRT2344697	hsa-miR-1293	CLIP-seq
MIRT2638003	hsa-miR-138	CLIP-seq
MIRT1408148	hsa-miR-181a	CLIP-seq
MIRT1408149	hsa-miR-181b	CLIP-seq
MIRT1408150	hsa-miR-181c	CLIP-seq
MIRT1408151	hsa-miR-181d	CLIP-seq
MIRT2122415	hsa-miR-1913	CLIP-seq
MIRT2638004	hsa-miR-2054	CLIP-seq
MIRT1408157	hsa-miR-3121-5p	CLIP-seq
MIRT2122421	hsa-miR-3143	CLIP-seq
MIRT2122422	hsa-miR-3159	CLIP-seq
MIRT1408162	hsa-miR-3189-5p	CLIP-seq
MIRT2122423	hsa-miR-324-3p	CLIP-seq
MIRT2122424	hsa-miR-3591-3p	CLIP-seq
MIRT2122425	hsa-miR-3655	CLIP-seq
MIRT2122426	hsa-miR-3668	CLIP-seq
MIRT2122427	hsa-miR-3691-3p	CLIP-seq
MIRT2638005	hsa-miR-376a	CLIP-seq
MIRT2638006	hsa-miR-376b	CLIP-seq
MIRT2638007	hsa-miR-3976	CLIP-seq
MIRT1408168	hsa-miR-4262	CLIP-seq
MIRT2638008	hsa-miR-4274	CLIP-seq
MIRT2638009	hsa-miR-4446-5p	CLIP-seq
MIRT2344711	hsa-miR-4483	CLIP-seq
MIRT2122436	hsa-miR-4515	CLIP-seq
MIRT2638010	hsa-miR-4519	CLIP-seq
MIRT2638011	hsa-miR-4524	CLIP-seq
MIRT2344716	hsa-miR-4536	CLIP-seq
MIRT2638012	hsa-miR-4668-3p	CLIP-seq
MIRT2344718	hsa-miR-4691-3p	CLIP-seq
MIRT2122441	hsa-miR-4694-3p	CLIP-seq
MIRT2344719	hsa-miR-4709-5p	CLIP-seq
MIRT2638013	hsa-miR-4738-3p	CLIP-seq
MIRT2122442	hsa-miR-4740-5p	CLIP-seq
MIRT2122444	hsa-miR-4758-3p	CLIP-seq
MIRT2344721	hsa-miR-4796-5p	CLIP-seq
MIRT1408189	hsa-miR-501-5p	CLIP-seq
MIRT2638014	hsa-miR-514	CLIP-seq
MIRT2638015	hsa-miR-514b-3p	CLIP-seq
MIRT2344722	hsa-miR-518a-5p	CLIP-seq
MIRT2344724	hsa-miR-527	CLIP-seq
MIRT2638016	hsa-miR-543	CLIP-seq
MIRT2344726	hsa-miR-582-5p	CLIP-seq
MIRT2344728	hsa-miR-656	CLIP-seq
MIRT2122406	hsa-miR-1228	CLIP-seq
MIRT2122408	hsa-miR-1269	CLIP-seq
MIRT2122409	hsa-miR-1269b	CLIP-seq
MIRT2122411	hsa-miR-1288	CLIP-seq
MIRT2344697	hsa-miR-1293	CLIP-seq
MIRT2638003	hsa-miR-138	CLIP-seq
MIRT1408148	hsa-miR-181a	CLIP-seq
MIRT1408149	hsa-miR-181b	CLIP-seq
MIRT1408150	hsa-miR-181c	CLIP-seq
MIRT1408151	hsa-miR-181d	CLIP-seq
MIRT2122415	hsa-miR-1913	CLIP-seq
MIRT2692589	hsa-miR-2052	CLIP-seq
MIRT2638004	hsa-miR-2054	CLIP-seq
MIRT1408157	hsa-miR-3121-5p	CLIP-seq
MIRT2122421	hsa-miR-3143	CLIP-seq
MIRT2122422	hsa-miR-3159	CLIP-seq
MIRT1408162	hsa-miR-3189-5p	CLIP-seq
MIRT2122423	hsa-miR-324-3p	CLIP-seq
MIRT2122424	hsa-miR-3591-3p	CLIP-seq
MIRT1408165	hsa-miR-3613-3p	CLIP-seq
MIRT2122425	hsa-miR-3655	CLIP-seq
MIRT2122426	hsa-miR-3668	CLIP-seq
MIRT2692590	hsa-miR-3672	CLIP-seq
MIRT2122427	hsa-miR-3691-3p	CLIP-seq
MIRT2638005	hsa-miR-376a	CLIP-seq
MIRT2638006	hsa-miR-376b	CLIP-seq
MIRT2638007	hsa-miR-3976	CLIP-seq
MIRT1408168	hsa-miR-4262	CLIP-seq
MIRT2638008	hsa-miR-4274	CLIP-seq
MIRT2692591	hsa-miR-4422	CLIP-seq
MIRT1408175	hsa-miR-4446-3p	CLIP-seq
MIRT2638009	hsa-miR-4446-5p	CLIP-seq
MIRT2344711	hsa-miR-4483	CLIP-seq
MIRT2122436	hsa-miR-4515	CLIP-seq
MIRT2638010	hsa-miR-4519	CLIP-seq
MIRT2638011	hsa-miR-4524	CLIP-seq
MIRT2344716	hsa-miR-4536	CLIP-seq
MIRT2638012	hsa-miR-4668-3p	CLIP-seq
MIRT1408183	hsa-miR-4675	CLIP-seq
MIRT2344718	hsa-miR-4691-3p	CLIP-seq
MIRT2122441	hsa-miR-4694-3p	CLIP-seq
MIRT2344719	hsa-miR-4709-5p	CLIP-seq
MIRT2638013	hsa-miR-4738-3p	CLIP-seq
MIRT2122442	hsa-miR-4740-5p	CLIP-seq
MIRT1408185	hsa-miR-4741	CLIP-seq
MIRT2122444	hsa-miR-4758-3p	CLIP-seq
MIRT1408188	hsa-miR-4768-5p	CLIP-seq
MIRT2638014	hsa-miR-514	CLIP-seq
MIRT2638015	hsa-miR-514b-3p	CLIP-seq
MIRT1408190	hsa-miR-515-5p	CLIP-seq
MIRT2344722	hsa-miR-518a-5p	CLIP-seq
MIRT2344724	hsa-miR-527	CLIP-seq
MIRT2638016	hsa-miR-543	CLIP-seq
MIRT2344726	hsa-miR-582-5p	CLIP-seq
MIRT1408211	hsa-miR-942	CLIP-seq

Show/Hide all(26)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000187	Process	Activation of MAPK activity	TAS
GO:0002223	Process	Stimulatory C-type lectin receptor signaling pathway	TAS
GO:0002755	Process	MyD88-dependent toll-like receptor signaling pathway	TAS
GO:0005515	Function	Protein binding	IPI	11460167, 11518704, 14743216, 16845370, 17158449, 17449468, 19026643, 19675569, 21512573, 21903422, 21988832, 22081109, 22158122, 22904686, 25260751, 27426733, 32296183
GO:0005654	Component	Nucleoplasm	TAS
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	TAS
GO:0007249	Process	I-kappaB kinase/NF-kappaB signaling	TAS
GO:0007254	Process	JNK cascade	TAS
GO:0007507	Process	Heart development	IMP	20493459
GO:0010008	Component	Endosome membrane	TAS
GO:0010507	Process	Negative regulation of autophagy	TAS	21976705
GO:0032496	Process	Response to lipopolysaccharide	IDA	19193853
GO:0038095	Process	Fc-epsilon receptor signaling pathway	TAS
GO:0043123	Process	Positive regulation of I-kappaB kinase/NF-kappaB signaling	IBA	21873635
GO:0043123	Process	Positive regulation of I-kappaB kinase/NF-kappaB signaling	IEP	12761501
GO:0043130	Function	Ubiquitin binding	IEA
GO:0045860	Process	Positive regulation of protein kinase activity	IBA	21873635
GO:0045860	Process	Positive regulation of protein kinase activity	IDA	11460167
GO:0046872	Function	Metal ion binding	IEA
GO:0050852	Process	T cell receptor signaling pathway	TAS
GO:0051092	Process	Positive regulation of NF-kappaB transcription factor activity	TAS
GO:0070423	Process	Nucleotide-binding oligomerization domain containing signaling pathway	TAS
GO:0070498	Process	Interleukin-1-mediated signaling pathway	TAS
GO:0070530	Function	K63-linked polyubiquitin modification-dependent protein binding	IBA	21873635
GO:0070530	Function	K63-linked polyubiquitin modification-dependent protein binding	IDA	19935683

MIM	HGNC	e!Ensembl
605101	17075	ENSG00000055208

Protein

UniProt ID

Q9NYJ8

Protein name

TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 2) (TAK1-binding protein 2) (TAB-2) (TGF-beta-activated kinase 1-binding protein 2)

Protein function

Adapter required to activate the JNK and NF-kappa-B signaling pathways through the specific recognition of 'Lys-63'-linked polyubiquitin chains by its RanBP2-type zinc finger (NZF) (PubMed:10882101, PubMed:11460167, PubMed:15327770, PubMed:22158

PDB

2DAE , 2WWZ , 2WX0 , 2WX1 , 9AVT , 9AVW

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF02845	CUE	9 → 50	CUE domain	Domain

Sequence

MAQGSHQIDFQVLHDLRQKFPEVPEVVVSRCMLQNNNNLDACCAVLSQESTRYLYGEGDL
NFSDDSGISGLRNHMTSLNLDLQSQNIYHHGREGSRMNGSRTLTHSISDGQLQGGQSNSE
LFQQEPQTAPAQVPQGFNVFGMSSSSGASNSAPHLGFHLGSKGTSSLSQQTPRFNPIMVT
LAPNIQTGRNTPTSLHIHGVPPPVLNSPQGNSIYIRPYITTPGGTTRQTQQHSGWVSQFN
PMNPQQVYQPSQPGPWTTCPASNPLSHTSSQQPNQQGHQTSHVYMPISSPTTSQPPTIHS
SGSSQSSAHSQYNIQNISTGPRKNQIEIKLEPPQRNNSSKLRSSGPRTSSTSSSVNSQTL
NRNQPTVYIAASPPNTDELMSRSQPKVYISANAATGDEQVMRNQPTLFISTNSGASAASR
NMSGQVSMGPAFIHHHPPKSRAIGNNSATSPRVVVTQPNTKYTFKITVSPNKPPAVSPGV
VSPTFELTNLLNHPDHYVETENIQHLTDPTLAHVDRISETRKLSMGSDDAAYTQALLVHQ
KARMERLQRELEIQKKKLDKLKSEVNEMENNLTRRRLKRSNSISQIPSLEEMQQLRSCNR
QLQIDIDCLTKEIDLFQARGPHFNPSAIHNFYDNIGFVGPVPPKPKDQRSIIKTPKTQDT
EDDEGAQWNCTACTFLNHPALIRCEQCEMPRHF

Sequence length

693

Interactions

View interactions

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