Gene
|
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
6776 |
Gene nameGene Name - the full gene name approved by the HGNC.
|
Signal transducer and activator of transcription 5A |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
|
STAT5A |
SynonymsGene synonyms aliases
|
MGF, STAT5 |
ChromosomeChromosome number
|
17 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
17q21.2 |
SummarySummary of gene provided in NCBI Entrez Gene.
|
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that tran |
miRNAmiRNA information provided by mirtarbase database.
|
|
Transcription factors
|
Transcription factor |
Regulation |
Reference |
PPARA |
Unknown |
21542777 |
|
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
|
|
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
|
|
Protein
|
UniProt ID |
P42229 |
Protein name |
Signal transducer and activator of transcription 5A |
Protein function |
Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated F |
PDB |
7TVA
,
7TVB
,
7UBT
,
7UC6
,
7UC7
|
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF02865 |
STAT_int |
2 → 124 |
STAT protein, protein interaction domain |
Domain |
PF01017 |
STAT_alpha |
141 → 324 |
STAT protein, all-alpha domain |
Family |
PF02864 |
STAT_bind |
336 → 469 |
STAT protein, DNA binding domain |
Domain |
PF00017 |
SH2 |
589 → 670 |
SH2 domain |
Domain |
|
Sequence |
|
Sequence length |
794 |
Interactions |
View interactions |