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SCD5 (stearoyl-CoA desaturase 5)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
79966
Gene nameGene Name - the full gene name approved by the HGNC.
Stearoyl-CoA desaturase 5
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
SCD5
SynonymsGene synonyms aliases
ACOD4, ACOD4 SCD2 SCD4, DFNA79, FADS4, HSCD5, SCD2, SCD4
ChromosomeChromosome number
4
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
4q21.22
SummarySummary of gene provided in NCBI Entrez Gene.
Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an integral membrane protein of the endoplasmic reticulum that catalyzes the formation of monounsaturated fatty acids from saturated fatty acids. SCD may be a key regulator of energy metabolism with a role in
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT021675 hsa-miR-140-3p Sequencing 20371350
MIRT049021 hsa-miR-92a-3p CLASH 23622248
MIRT047892 hsa-miR-30c-5p CLASH 23622248
MIRT043059 hsa-miR-324-5p CLASH 23622248
MIRT718597 hsa-miR-141-3p HITS-CLIP 19536157
Transcription factors
Transcription factor Regulation Reference
EGR2 Repression 22510410
SREBF1 Activation 22510410
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0004768 Function Stearoyl-CoA 9-desaturase activity IBA 21873635
GO:0004768 Function Stearoyl-CoA 9-desaturase activity IDA 15907797, 22745828
GO:0005506 Function Iron ion binding IBA 21873635
GO:0005789 Component Endoplasmic reticulum membrane IBA 21873635
GO:0005789 Component Endoplasmic reticulum membrane IDA 15907797
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q86SK9
Protein name Stearoyl-CoA desaturase 5 (EC 1.14.19.1) (Acyl-CoA-desaturase 4) (HSCD5) (Stearoyl-CoA 9-desaturase) (Stearoyl-CoA desaturase 2)
Protein function Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00487 FA_desaturase
72 291
Fatty acid desaturase
Domain
Sequence
Sequence length 330
Interactions View interactions

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